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|
##################################################################
##
## file: rma.background.correct.R
##
## implements the normal boackground + exponential signal background
## correction traditionally used in RMA computations
##
## for more details see
## Bolstad, BM (2004) Low Level Analysis of High-density Oligonucleotide Array Data: Background, Normalization and Summarization. Dissertation. University of California, Berkeley.
## pages 17-21
##
##
## History
## Mar 22, 2008 - Initial version (in preprocessCore)
##
##
rma.background.correct <- function(x,copy=TRUE){
rows <- dim(x)[1]
cols <- dim(x)[2]
if (!is.matrix(x)){
stop("Matrix expected in normalize.quantiles")
}
if (is.integer(x)){
x <- matrix(as.double(x),rows,cols)
copy <- FALSE
}
.Call("R_rma_bg_correct", x, copy, PACKAGE="preprocessCore");
}
|
