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\name{Sachs}
\alias{Sachs}
\title{Protein Expression in Human Immune System Cells}
\description{
Data concerning protein expression levels in human immune system
cells under stimulations.
}
\usage{data(Sachs)}
\format{
A data frame containing 7466 cells, with flow cytometry measurements
of 11 phosphorylated proteins and phospholipids, on the \code{log10}
scale of the original.
\tabular{ll}{
\code{praf} \tab Raf phosphorylated at S259.\cr
\code{pmek} \tab Mek1/mek2 phosphorylated at S217/S221.\cr
\code{plcg} \tab Phosphorylation of phospholipase \eqn{C-\gamma}
on Y783.\cr
\code{pip2} \tab Phophatidylinositol 4,5-biphosphate.\cr
\code{pip3} \tab Phophatidylinositol 3,4,5-triphosphate.\cr
\code{p44.42} \tab Erk1/erk2 phosphorylated at T202/Y204.\cr
\code{pakts473} \tab AKT phosphorylated at S473.\cr
\code{pka} \tab Phosphorylation of of protein kinase A
substrates on 3 sites.\cr
\code{pkc} \tab Phosphorylation of of protein kinase C
substrates on S660.\cr
\code{p38} \tab Erk1/erk2 phosphorylated at T180/Y182.\cr
\code{pjnk} \tab Erk1/erk2 phosphorylated at T183/Y185.\cr
}
}
\source{
Sachs, K., Perez, O., Pe'er, D., Lauffenburger, D. A., and Nolan,
G. P. (2005), Causal protein-signaling networks derived from
multiparameter single-cell data. \emph{Science}, \bold{308 (5732)},
523--529.
}
\keyword{datasets}
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