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% Generated by roxygen2: do not edit by hand
% Please edit documentation in R/toenail.R
\docType{data}
\name{toenail}
\alias{toenail}
\title{Toenail data}
\format{
A data frame with 1908 observations on the following 5 variables:
\describe{
\item{\code{ID}}{a numeric vector giving the ID of patient}
\item{\code{outcome}}{a numeric vector giving the response
(0=none or mild seperation, 1=moderate or severe)}
\item{\code{treatment}}{a numeric vector giving the treatment group}
\item{\code{month}}{a numeric vector giving the time of the visit
(not exactly monthly intervals hence not round numbers)}
\item{\code{visit}}{a numeric vector giving the number of the visit}
}
}
\source{
De Backer, M., De Vroey, C., Lesaffre, E., Scheys, I., and De
Keyser, P. (1998). Twelve weeks of continuous oral therapy for
toenail onychomycosis caused by dermatophytes: A double-blind
comparative trial of terbinafine 250 mg/day versus itraconazole 200
mg/day. Journal of the American Academy of Dermatology, 38, 57-63.
}
\description{
The toenail data come from a Multicenter study comparing two oral
treatments for toenail infection. Patients were evaluated for the
degree of separation of the nail. Patients were randomized into two
treatments and were followed over seven visits - four in the first
year and yearly thereafter. The patients have not been treated
prior to the first visit so this should be regarded as the
baseline.
}
\details{
This dataset was copied from the \code{DPpackage}, which is
scheduled to be discontinued from CRAN in August 2019.
}
\references{
Lesaffre, E. and Spiessens, B. (2001). On the effect of the number of
quadrature points in a logistic random-effects model: An example.
Journal of the Royal Statistical Society, Series C, 50, 325-335.
G. Fitzmaurice, N. Laird and J. Ware (2004) Applied Longitudinal Analysis,
Wiley and Sons, New York, USA.
Van Buuren, S. (2018).
\href{https://stefvanbuuren.name/fimd/sec-catoutcome.html#example}{\emph{Flexible
Imputation of Missing Data. Second Edition.}} Chapman & Hall/CRC.
Boca Raton, FL.
}
\seealso{
\code{\link{toenail2}}
}
\keyword{datasets}
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