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## Annotations.
## Conceptually, a single annotation is a quintuple with "slots" id,
## type, start, end and features, and our Annotation objects are
## sequences (to allow positional access) of annotations, i.e., sequence
## of such quintuples.
## The implementation actually uses a "quintuple" (named list of length
## five) with slots giving the respective sequences of slot values.
## The feature slot of a single annotation is a feature map which we
## represent as named lists (at least for now also allowing NULL for an
## empty feature map), hence the sequence of feature values is a list of
## named lists.
## Subscripting via [ extracts subsets of annotations.
## Subscripting via $ extracts one slot value sequence.
## As Annotation objects have all slots of Span objects, we take them to
## have class "Annotation" and also inherit from class "Span".
## We allow for ids to be missing, and Annotation(id = NULL) creates
## missing ids as needed.
Annotation_classes <- c("Annotation", "Span")
Annotation_slot_names <- c("id", "type", "start", "end", "features")
Annotation <-
function(id = NULL, type = NULL, start, end, features = NULL,
meta = list())
{
if(nargs() == 0L) {
## Could also provide default values (e.g., NULL) for all
## arguments ...
return(.Annotation_from_args(integer(),
character(),
integer(),
integer(),
list(),
meta))
}
start <- as.integer(start)
end <- as.integer(end)
n <- length(start)
id <- if(is.null(id))
rep.int(NA_integer_, n)
else
as.integer(id)
type <- if(is.null(type))
rep.int(NA_character_, n)
else
as.character(type)
features <- if(is.null(features))
rep.int(list(list()), n)
else
lapply(features, as.list)
## <TODO>
## Should perhaps check that all elements of 'features' are named or
## empty lists.
## </TODO>
.Annotation_from_args(id, type, start, end, features, meta)
}
.Annotation_from_args <-
function(id, type, start, end, features, meta)
{
x <- list(id, type, start, end, features)
if(any(diff(sapply(x, length)) != 0L))
stop("arguments must have the same length")
names(x) <- Annotation_slot_names
.Annotation_from_list_and_meta(x, meta)
}
.Annotation_from_list_and_meta <-
function(x, meta)
{
class(x) <- Annotation_classes
attr(x, "meta") <- meta
x
}
as.Annotation <-
function(x, ...)
UseMethod("as.Annotation")
as.Annotation.Annotation <-
function(x, ...)
x
as.Annotation.Span <-
function(x, id = NULL, type = NULL, ...)
{
## Call Annotation() so we get coercion and length checking.
Annotation(id, type, x$start, x$end, NULL)
}
is.Annotation <-
function(x)
inherits(x, "Annotation")
`[.Annotation` <-
function(x, i)
.Annotation_from_list_and_meta(lapply(unclass(x), `[`, i),
attr(x, "meta"))
## <TODO>
## Implement eventually ...
`[<-.Annotation` <-
function(x, i, value)
.NotYetImplemented()
## </TODO>
`[[.Annotation` <-
function(x, i)
{
y <- lapply(unclass(x), `[[`, i)
y$features <- list(y$features)
.Annotation_from_list_and_meta(y, attr(x, "meta"))
}
## <TODO>
## Implement eventually ...
`[[<-.Annotation` <-
function(x, i, value)
.NotYetImplemented()
## </TODO>
## $.Annotation is not really necessary.
`$<-.Annotation` <-
function(x, name, value)
{
n <- length(x)
x <- unclass(x)
if(is.na(pos <- pmatch(name, Annotation_slot_names)))
stop("invalid element name")
name <- Annotation_slot_names[pos]
value <- if(name == "type")
as.character(value)
else if(name == "features")
as.list(value)
else
as.integer(value)
## This is not very elegant: we could record the slot modes as
## Annotation_slot_modes <-
## c("integer", "character", "integer", "integer", "list")
## but then coercion via the respective as.MODE functions would need
## some trickery ... maybe do this at a later stage, and modify the
## Annotation() creator accordingly.
if(length(value) != n)
stop("replacement must have the same length as object")
x[[pos]] <- value
.Annotation_from_list_and_meta(x, attr(x, "meta"))
}
as.data.frame.Annotation <-
function(x, row.names = NULL, optional = FALSE, ...)
{
y <- data.frame(id = x$id,
type = x$type,
start = x$start,
end = x$end,
stringsAsFactors = FALSE,
row.names = row.names)
y$features <- x$features
y
}
as.list.Annotation <-
function(x, ...)
lapply(seq_along(x), function(i) x[i])
c.Annotation <-
function(..., recursive = FALSE)
{
args <- lapply(list(...), as.Annotation)
meta <- do.call(c, lapply(args, meta))
args <- lapply(args, unclass)
y <- lapply(Annotation_slot_names,
function(e) unlist(lapply(args, `[[`, e),
recursive = FALSE))
names(y) <- Annotation_slot_names
## Remove *exact* duplicates from metadata:
if(length(meta)) {
meta <- tapply(meta, names(meta), unique, simplify = FALSE)
tags <- rep.int(names(meta), sapply(meta, length))
meta <- unlist(meta, recursive = FALSE, use.names = FALSE)
names(meta) <- tags
}
.Annotation_from_list_and_meta(y, meta)
}
## This is at the mercy of duplicated() working well on lists ...
duplicated.Annotation <-
function(x, incomparables = FALSE, ...)
{
Reduce(`&`, lapply(unclass(x), duplicated))
}
format.Annotation <-
function(x, values = TRUE, ...)
{
if(!length(x)) return(character())
y <- .format_Annotation_without_features(x)
wy <- nchar(y[1L], type = "width")
wf <- max(16L, 0.95 * getOption("width") - wy)
collapse <- format("\n", width = wy + 2L)
features <- lapply(x$features, function(e) {
if(!(l <- length(e))) return("")
s <- if(values) .format_feature_map(e) else names(e)
s <- paste0(s, c(rep_len(",", l - 1L), ""))
w <- nchar(strwrap(paste(gsub(".", "X", s), collapse = " "),
width = wf))
v <- c(0L, head(cumsum(w + 1L), -1L))
f <- v + 1L
t <- v + w
paste(substring(paste(s, collapse = " "), f, t),
collapse = collapse)
})
paste0(y, c("features", features), collapse = "\n")
}
inspect.Annotation <-
function(x)
{
x$features <-
vapply(x$features,
function(e) {
if(length(s <- .format_feature_map(e))) {
paste(sprintf("\n %s", s), collapse = "")
} else NA_character_
},
"")
write.dcf(x, keep.white = "features")
}
length.Annotation <-
function(x)
length(x$start)
merge.Annotation <-
function(x, y, ...)
{
pos <- match(paste(y$id, y$type, y$start, y$end, sep = "\r"),
paste(x$id, x$type, x$start, x$end, sep = "\r"),
nomatch = 0L)
## <NOTE>
## This should really combine the unique tag/value pairs.
## In fact, duplicated tags are a problem, but how should they be
## handled (take the pair from x or from y)?
x$features[pos] <- Map(c, x$features[pos], y$features[pos > 0L])
## </NOTE>
c(x, y[pos == 0L])
}
## meta.Annotation <-
## function(x, tag = NULL, ...)
## {
## m <- attr(x, "meta")
## if(is.null(tag)) m else m[[tag]]
## }
## `meta<-.Annotation` <-
## function(x, tag = NULL, ..., value)
## {
## if(is.null(tag))
## attr(x, "meta") <- value
## else
## attr(x, "meta")[[tag]] <- value
## x
## }
names.Annotation <-
function(x)
NULL
## print.Annotation <-
## function(x, values = TRUE, ...)
## {
## writeLines(format(x, values = values))
## invisible(x)
## }
subset.Annotation <-
function(x, subset, ...)
{
e <- substitute(subset)
i <- eval(e, unclass(x), parent.frame())
if(!is.logical(i))
stop("'subset' must be logical")
i <- i & !is.na(i)
x[i]
}
unique.Annotation <-
function(x, incomparables = FALSE, ...)
x[!duplicated(x)]
.format_Annotation_without_features <-
function(x)
{
sprintf(" %s %s %s %s ",
.format_values_with_header(x$id, "id", "right"),
.format_values_with_header(x$type, "type", "left"),
.format_values_with_header(x$start, "start", "right"),
.format_values_with_header(x$end, "end", "right"))
}
.format_values_with_header <-
function(v, h, justify = c("left", "right"))
{
justify <- match.arg(justify)
width <- max(nchar(h), nchar(v))
len <- length(v)
fmt <- sprintf("%%%s%ds",
c("-", rep.int(if(justify == "left") "-" else "", len)),
rep.int(width, len + 1L))
sprintf(fmt, c(h, v))
}
## Try formatting feature maps nicely.
## Similar to what we do in package 'sets', I guess ...
.format_feature_map <-
function(x, ...)
{
if(!length(x)) return(character())
.fmt <- function(v) {
## Formatter for a single value.
if(is.object(v))
sprintf("<<%s>>", class(v)[1L])
else if(is.array(v))
sprintf("<<array,%s>>", paste(dim(v), collapse = ","))
else if(is.character(v) && (length(v) == 1L)) {
if(nchar(v) <= 32L) v else "<<character,1>>"
} else if(is.atomic(v) && (length(v) == 1L)) {
## <FIXME>
## Should this take ... args?
## Also, might want to ensure this does not get too long.
format(v)
## </FIXME>
} else if(is.vector(v))
sprintf("<<%s,%s>>", typeof(v), length(v))
else if(is.null(v))
"NULL"
else
"<<???>>"
}
sprintf("%s=%s", names(x), vapply(x, .fmt, ""))
}
annotations_in_spans <-
function(x, y)
{
y <- as.Span(y)
## An annotation node is contained in a span if it does not start
## ahead of the span and does not end later than the span.
ind <- outer(x$start, y$start, ">=") & outer(x$end, y$end, "<=")
lapply(seq_len(ncol(ind)), function(j) x[ind[, j]])
}
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