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#include <iostream>
#include <seqan/file.h>
#include <seqan/sequence.h>
#include <seqan/score.h>
using namespace seqan;
template <typename TText>
int computeLocalScore(TText const & subText, String<AminoAcid> const & pattern)
{
int localScore = 0;
for (unsigned i = 0; i < length(pattern); ++i)
localScore += score(Blosum62(), subText[i], pattern[i]);
return localScore;
}
template <typename TText, typename TPattern>
int computeLocalScore(TText const & subText, TPattern const & pattern)
{
int localScore = 0;
for (unsigned i = 0; i < length(pattern); ++i)
if (subText[i] == pattern[i])
++localScore;
return localScore;
}
template <typename TText, typename TPattern>
String<int> computeScore(TText const & text, TPattern const & pattern)
{
String<int> score;
resize(score, length(text) - length(pattern) + 1, 0);
for (unsigned i = 0; i < length(text) - length(pattern) + 1; ++i)
score[i] = computeLocalScore(infix(text, i, i + length(pattern)), pattern);
return score;
}
template <typename TText>
void print(TText const & text)
{
std::cout << text << std::endl;
}
void print(String<int> const & text)
{
for (unsigned i = 0; i < length(text); ++i)
std::cout << text[i] << " ";
std::cout << std::endl;
}
template <typename TText, typename TSpec>
void print(TText const & text, TSpec const & /*tag*/)
{
print(text);
}
struct MaxOnly {};
template <typename TText>
void print(TText const & score, MaxOnly const & /*tag*/)
{
int maxScore = score[0];
String<int> output;
appendValue(output, 0);
for (unsigned i = 1; i < length(score); ++i)
{
if (score[i] > maxScore)
{
maxScore = score[i];
clear(output);
resize(output, 1, i);
}
else if (score[i] == maxScore)
appendValue(output, i);
}
print(output);
}
struct GreaterZero {};
template <typename TText>
void print(TText const & score, GreaterZero const & /*tag*/)
{
String<Pair<int> > output;
for (unsigned i = 1; i < length(score); ++i)
if (score[i] > 0)
appendValue(output, Pair<int>(i, score[i]));
for (unsigned i = 0; i < length(output); ++i)
std::cout << "(" << output[i].i1 << "; " << output[i].i2 << ") ";
std::cout << std::endl;
}
int main()
{
String<char> text = "This is an awesome tutorial to get to know SeqAn!";
String<char> pattern = "tutorial";
String<int> score = computeScore(text, pattern);
print(text);
print(pattern);
print(score);
print(score, MaxOnly());
print(score, GreaterZero());
// And now for a protein pattern
String<AminoAcid> protein = "tutorial";
String<int> proteinScore = computeScore(text, protein);
print(text);
print(protein);
print(proteinScore);
print(proteinScore, MaxOnly());
print(proteinScore, GreaterZero());
return 0;
}
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