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// ==========================================================================
// SeqAn - The Library for Sequence Analysis
// ==========================================================================
// Copyright (c) 2006-2018, Knut Reinert, FU Berlin
// All rights reserved.
//
// Redistribution and use in source and binary forms, with or without
// modification, are permitted provided that the following conditions are met:
//
// * Redistributions of source code must retain the above copyright
// notice, this list of conditions and the following disclaimer.
// * Redistributions in binary form must reproduce the above copyright
// notice, this list of conditions and the following disclaimer in the
// documentation and/or other materials provided with the distribution.
// * Neither the name of Knut Reinert or the FU Berlin nor the names of
// its contributors may be used to endorse or promote products derived
// from this software without specific prior written permission.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
// AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
// IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
// ARE DISCLAIMED. IN NO EVENT SHALL KNUT REINERT OR THE FU BERLIN BE LIABLE
// FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
// DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
// SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
// CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
// LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
// OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH
// DAMAGE.
//
// ==========================================================================
// Author: Rene Rahn <rene.rahn@fu-berlin.de>
// ==========================================================================
#ifndef INCLUDE_SEQAN_ALIGN_PARALLEL_WAVEFRONT_TASK_UTIL_H_
#define INCLUDE_SEQAN_ALIGN_PARALLEL_WAVEFRONT_TASK_UTIL_H_
namespace seqan
{
namespace impl
{
// ============================================================================
// Forwards
// ============================================================================
// ============================================================================
// Tags, Classes, Enums
// ============================================================================
// ============================================================================
// Metafunctions
// ============================================================================
// Helper meta-function to extract the correct DP Property.
template <typename TAlgotrithm>
struct AlgorithmProperty
{
template <typename TTask>
inline static bool
isTrackingEnabled(TTask const & tile)
{
return isLastColumn(tile) && isLastRow(tile);
}
};
template <typename TFreeEndGaps>
struct AlgorithmProperty<GlobalAlignment_<TFreeEndGaps>>
{
template <typename TTask>
inline static bool
isTrackingEnabled(TTask const & tile)
{
return (IsFreeEndGap_<TFreeEndGaps, DPLastColumn>::VALUE && inLastColumn(tile)) ||
(IsFreeEndGap_<TFreeEndGaps, DPLastRow>::VALUE && inLastRow(tile)) ||
(inLastColumn(tile) && inLastRow(tile));
}
};
template <typename TSpec>
struct AlgorithmProperty<LocalAlignment_<TSpec>>
{
template <typename TTask>
inline static bool
isTrackingEnabled(TTask const & /*tile*/)
{
return true;
}
};
// ============================================================================
// Functions
// ============================================================================
// ----------------------------------------------------------------------------
// Function computeTile()
// ----------------------------------------------------------------------------
// Wrapper function to call alignment core for the specific block.
template <typename TScoreValue, typename TTraceValue, typename TScoreMatHost, typename TTraceMatHost,
typename TDPScout,
typename TSequenceH,
typename TSequenceV,
typename TScoringScheme,
typename TDPSettings>
inline void
computeTile(DPContext<TScoreValue, TTraceValue, TScoreMatHost, TTraceMatHost> & dpContext,
TDPScout & scout,
TSequenceH const & seqH,
TSequenceV const & seqV,
TScoringScheme const & scoringScheme,
TDPSettings const & /*settings*/)
{
using TDPTraits = typename TDPSettings::TTraits;
using TScoreMatrixSpec = typename DefaultScoreMatrixSpec_<typename TDPTraits::TAlgorithmType>::Type;
using TDPScoreMatrix = DPMatrix_<TScoreValue, TScoreMatrixSpec, TScoreMatHost>;
using TDPTraceMatrix = DPMatrix_<TTraceValue, FullDPMatrix, TTraceMatHost>;
using TDPScoreMatrixNavigator = DPMatrixNavigator_<TDPScoreMatrix, DPScoreMatrix, NavigateColumnWise>;
using TDPTraceMatrixNavigator = DPMatrixNavigator_<TDPTraceMatrix, DPTraceMatrix<typename TDPTraits::TTracebackType>, NavigateColumnWise>;
using TDPProfile = DPProfile_<typename TDPTraits::TAlgorithmType,
typename TDPTraits::TGapType,
typename TDPTraits::TTracebackType,
Parallel>;
// Setup the score and trace matrix.
TDPScoreMatrix dpScoreMatrix;
TDPTraceMatrix dpTraceMatrix;
setLength(dpScoreMatrix, +DPMatrixDimension_::HORIZONTAL, length(seqH) + 1);
setLength(dpScoreMatrix, +DPMatrixDimension_::VERTICAL, length(seqV) + 1);
setLength(dpTraceMatrix, +DPMatrixDimension_::HORIZONTAL, length(seqH) + 1);
setLength(dpTraceMatrix, +DPMatrixDimension_::VERTICAL, length(seqV) + 1);
// Resue the buffer from the cache.
setHost(dpScoreMatrix, getDpScoreMatrix(dpContext));
setHost(dpTraceMatrix, getDpTraceMatrix(dpContext));
resize(dpScoreMatrix);
// We do not need to allocate the memory for the trace matrix if the traceback is disabled.
if /*constexpr*/(IsTracebackEnabled_<typename TDPTraits::TTracebackType>::VALUE)
{
static_assert(std::is_same<typename TDPTraits::TTracebackType, TracebackOff>::value, "Traceback not implemented!");
resize(dpTraceMatrix);
}
// Initialize the navigators.
TDPScoreMatrixNavigator dpScoreMatrixNavigator{dpScoreMatrix, DPBandConfig<BandOff>{}};
TDPTraceMatrixNavigator dpTraceMatrixNavigator{dpTraceMatrix, DPBandConfig<BandOff>{}};
// Execute the alignment.
_computeAlignmentImpl(scout, dpScoreMatrixNavigator, dpTraceMatrixNavigator, seqH, seqV,
scoringScheme, DPBandConfig<BandOff>{}, TDPProfile(), NavigateColumnWise{});
}
#ifdef SEQAN_SIMD_ENABLED
// Some utility functions.
template <typename TTasks,
typename TScoreValueScalar,
typename TScoreValueSimd>
inline auto
doComputeOffset(TTasks const &tasks,
TScoreValueScalar const & /*scalarScore*/,
TScoreValueSimd const & /*simdScore*/)
{
String<TScoreValueScalar> offset;
resize(offset, length(tasks), std::numeric_limits<TScoreValueScalar>::min(), Exact());
size_t pos = 0;
for (auto task : tasks)
{
offset[pos] = front(context(*task).tileBuffer.horizontalBuffer[column(*task)]).i1._score;
++pos;
}
return offset;
}
template <typename TTasks,
typename TScoreValue>
inline auto
doComputeOffset(TTasks const &tasks,
TScoreValue const & /*scalarScore*/,
TScoreValue const & /*simdScore*/)
{
String<TScoreValue> offset;
resize(offset, length(tasks), 0, Exact());
return offset;
}
template <typename TTasks,
typename TTaskTraits>
inline auto
computeOffset(TTasks const &tasks, TTaskTraits const & /*traits*/)
{
using TDPSettings = typename TTaskTraits::TDPSettings;
using TScoreValueScalar = typename Value<typename TDPSettings::TScoringScheme>::Type;
using TScoreValueSimd = typename Value<typename TDPSettings::TSimdScoringScheme>::Type;
using TDPSimdValue = typename Value<TScoreValueSimd>::Type;
return doComputeOffset(tasks, TScoreValueScalar{}, TDPSimdValue{});
}
template <typename TDPCell, typename TTrace,
typename TTasks,
typename TPos,
typename TFunc,
typename TOffset>
inline void
loadIntoSimd(Pair<TDPCell, TTrace> & target,
TTasks const & tasks,
TPos const pos,
TFunc && getBuffer,
TOffset const & offset,
LinearGaps const & /*unsused*/)
{
using TSimdVec = typename Value<TDPCell>::Type;
using TVecVal = typename Value<TSimdVec>::Type;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> traceVec;
auto zipCont = makeZipView(tasks, scoreVec, traceVec, offset);
std::for_each(begin(zipCont), end(zipCont),
[&, getBuffer = std::move(getBuffer)](auto tuple)
{
auto & buffer = *getBuffer(*std::get<0>(tuple));
auto val = (length(buffer) > pos) ? buffer[pos] : typename std::decay<decltype(buffer[0])>::type{};
// We might access values out of bounds here.
std::get<1>(tuple) = static_cast<TVecVal>(val.i1._score - std::get<3>(tuple));
std::get<2>(tuple) = val.i2;
});
target.i1._score = load<TSimdVec>(&scoreVec[0]);
target.i2 = load<TSimdVec>(&traceVec[0]);
}
template <typename TDPCell, typename TTrace,
typename TTasks,
typename TPos,
typename TFunc,
typename TOffset>
inline void
loadIntoSimd(Pair<TDPCell, TTrace> & target,
TTasks const & tasks,
TPos const pos,
TFunc && getBuffer,
TOffset const & offset,
AffineGaps const & /*unsused*/)
{
using TSimdVec = typename Value<TDPCell>::Type;
using TVecVal = typename Value<TSimdVec>::Type;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreHorVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreVerVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> traceVec;
auto zipCont = makeZipView(tasks, scoreVec, scoreHorVec, scoreVerVec, traceVec, offset);
std::for_each(begin(zipCont), end(zipCont),
[&, getBuffer = std::move(getBuffer)](auto tuple)
{
auto & buffer = *getBuffer(*std::get<0>(tuple));
auto val = (length(buffer) > pos) ? buffer[pos] : typename std::decay<decltype(buffer[0])>::type{};
using TDPCellVar = decltype(val.i1);
using TDPCell16 = DPCell_<TVecVal, AffineGaps>;
// We might access values out of bounds here.
std::get<1>(tuple) = static_cast<TVecVal>(val.i1._score - std::get<5>(tuple));
std::get<2>(tuple) =
(val.i1._horizontalScore <= DPCellDefaultInfinity<TDPCellVar>::VALUE) ?
DPCellDefaultInfinity<TDPCell16>::VALUE :
static_cast<TVecVal>(val.i1._horizontalScore - std::get<5>(tuple));
std::get<3>(tuple) =
(val.i1._verticalScore <= DPCellDefaultInfinity<TDPCellVar>::VALUE) ?
DPCellDefaultInfinity<TDPCell16>::VALUE :
static_cast<TVecVal>(val.i1._verticalScore - std::get<5>(tuple));
std::get<4>(tuple) = val.i2;
});
target.i1._score = load<TSimdVec>(&scoreVec[0]);
target.i1._horizontalScore = load<TSimdVec>(&scoreHorVec[0]);
target.i1._verticalScore = load<TSimdVec>(&scoreVerVec[0]);
target.i2 = load<TSimdVec>(&traceVec[0]);
}
template <typename TTasks,
typename TDPCell, typename TTrace,
typename TPos,
typename TFunc,
typename TOffset>
inline void
storeIntoBuffer(TTasks & tasks,
Pair<TDPCell, TTrace> const & source,
TPos const pos,
TFunc && getBuffer,
TOffset const & offset,
LinearGaps const & /*unsused*/)
{
using TSimdVec = typename Value<TDPCell>::Type;
using TVecVal = typename Value<TSimdVec>::Type;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> traceVec;
storeu(&scoreVec[0], source.i1._score);
storeu(&traceVec[0], source.i2);
auto zipCont = makeZipView(tasks, scoreVec, traceVec, offset);
std::for_each(begin(zipCont), end(zipCont),
[&, getBuffer = std::move(getBuffer)] (auto tuple)
{
auto & buffer = *getBuffer(*std::get<0>(tuple));
if (length(buffer) > pos)
{
auto & pair = buffer[pos];
pair.i1._score = std::get<1>(tuple) + std::get<3>(tuple);
pair.i2 = std::get<2>(tuple);
}
});
}
template <typename TTasks,
typename TDPCell, typename TTrace,
typename TPos,
typename TFunc,
typename TOffset>
inline void
storeIntoBuffer(TTasks & tasks,
Pair<TDPCell, TTrace> const & source,
TPos const pos,
TFunc && getBuffer,
TOffset const & offset,
AffineGaps const & /*unsused*/)
{
using TSimdVec = typename Value<TDPCell>::Type;
using TVecVal = typename Value<TSimdVec>::Type;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreHorVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> scoreVerVec;
alignas(sizeof(TSimdVec)) std::array<TVecVal, LENGTH<TSimdVec>::VALUE> traceVec;
storeu(&scoreVec[0], source.i1._score);
storeu(&scoreHorVec[0], source.i1._horizontalScore);
storeu(&scoreVerVec[0], source.i1._verticalScore);
storeu(&traceVec[0], source.i2);
auto zipCont = makeZipView(tasks, scoreVec, scoreHorVec, scoreVerVec, traceVec, offset);
std::for_each(begin(zipCont), end(zipCont),
[&, getBuffer = std::move(getBuffer)](auto tuple)
{
auto & buffer = *getBuffer(*std::get<0>(tuple));
if (length(buffer) > pos)
{
auto & pair = buffer[pos];
pair.i1._score = std::get<1>(tuple) + std::get<5>(tuple);
pair.i1._horizontalScore = std::get<2>(tuple) + std::get<5>(tuple);
pair.i1._verticalScore = std::get<3>(tuple) + std::get<5>(tuple);
pair.i2 = std::get<4>(tuple);
}
});
}
template <typename TTasks,
typename TFunc,
typename TOffset,
typename TExecTraits>
inline auto
gatherSimdBuffer(TTasks const & tasks,
TFunc && getBuffer,
TOffset const & offset,
TExecTraits const & /*traits*/)
{
// Check for valid simd length.
SEQAN_ASSERT_EQ(LENGTH<typename TExecTraits::TScoreValue>::VALUE, length(tasks));
String<typename TExecTraits::TBufferValue, Alloc<OverAligned> > simdSet;
auto maxLength = length(*getBuffer(*tasks[0]));
std::for_each(begin(tasks, Standard()) + 1, end(tasks, Standard()),
[&](auto & task)
{
auto len = length(*getBuffer(*task));
maxLength = (len > maxLength) ? len : maxLength;
});
resize(simdSet, maxLength, Exact());
for (unsigned i = 0; i < length(simdSet); ++i)
{
loadIntoSimd(simdSet[i], tasks, i, std::forward<TFunc>(getBuffer), offset, typename TExecTraits::TGapType());
}
return simdSet;
}
template <typename TTasks,
typename TBufferValue, typename TSpec,
typename TFunc,
typename TOffset,
typename TExecTraits>
inline void
scatterSimdBuffer(TTasks & tasks,
String<TBufferValue, TSpec> const & simdSet,
TFunc && getBuffer,
TOffset const & offset,
TExecTraits const & /*traits*/)
{
for (unsigned i = 0; i < length(simdSet); ++i)
{
storeIntoBuffer(tasks, simdSet[i], i, std::forward<TFunc>(getBuffer), offset, typename TExecTraits::TGapType());
}
}
// Compute tasks as simd alignment.
template <typename TDPCell, typename TTraceValue, typename TScoreMat, typename TTraceMat,
typename TTasks,
typename TSimdBufferH,
typename TSimdBufferV,
typename TDPLocal,
typename TOffset,
typename TExecTraits>
inline void
computeSimdBatch(DPContext<TDPCell, TTraceValue, TScoreMat, TTraceMat> & cache,
TSimdBufferH & bufferH,
TSimdBufferV & bufferV,
TTasks & tasks,
TDPLocal & dpLocal,
TOffset & offset,
TExecTraits const & /*traits*/)
{
// Now what?
using TSeqH = typename TExecTraits::TSeqH;
using TSeqV = typename TExecTraits::TSeqV;
using TSimdVec = typename TExecTraits::TScoreValue;
// Prepare sequence set.
StringSet<TSeqH, Dependent<> > depSetH;
StringSet<TSeqV, Dependent<> > depSetV;
bool allSameLength = true;
auto ptrTask = tasks[0];
auto lenH = length(context(*ptrTask).seqHBlocks[column(*ptrTask)]);
auto lenV = length(context(*ptrTask).seqVBlocks[row(*ptrTask)]);
for (auto ptrTask : tasks)
{
appendValue(depSetH, context(*ptrTask).seqHBlocks[column(*ptrTask)]);
appendValue(depSetV, context(*ptrTask).seqVBlocks[row(*ptrTask)]);
if (lenH != length(context(*ptrTask).seqHBlocks[column(*ptrTask)]) ||
lenV != length(context(*ptrTask).seqVBlocks[row(*ptrTask)]))
{
allSameLength = false;
}
}
// Dummy trace set.
StringSet<String<Nothing> > trace; // We need to instantiate it, but it will not be used.
// We can compute with one simd score, but might collect them here.
auto const & scoringScheme = context(*tasks[0]).dpSettings.simdScoringScheme;
// Preapare and run alingment.
String<TSimdVec, Alloc<OverAligned> > stringSimdH;
String<TSimdVec, Alloc<OverAligned> > stringSimdV;
if (allSameLength)
{
using TScoutState = DPScoutState_<DPTiled<TSimdBufferH, Default, SimdAlignEqualLength>>;
TScoutState scoutState(bufferH, bufferV);
_prepareSimdAlignment(stringSimdH, stringSimdV, depSetH, depSetV, scoutState);
using TScoutSpec = typename ScoutSpecForAlignmentAlgorithm_<typename TExecTraits::TAlgorithmType, TScoutState>::Type;
using TDPScout = DPScout_<TDPCell, TScoutSpec>;
TDPScout dpScout(scoutState);
// We rather want to set
computeTile(cache, dpScout, stringSimdH, stringSimdV, scoringScheme, context(*tasks[0]).dpSettings);
// Now we need to run the scout check for all tasks.
// We want to get the state here from the scout.
for (size_t pos = 0; pos < length(tasks); ++pos)
{
auto & task = *tasks[pos];
if (AlgorithmProperty<typename TExecTraits::TAlgorithmType>::isTrackingEnabled(task))
{
// TODO(rrahn): Implement the interface.
// TODO(rrahn): Make it a member function of a policy so that we don't have to implement the specifics here
_setSimdLane(dpScout, pos);
auto & taskContext = context(task);
updateMax(intermediate(dpLocal, taskContext.alignmentId),
{maxScoreAt(dpScout) + offset[pos], 0u},
column(task),
row(task));
}
}
}
else
{
using TDPSettings = std::decay_t<decltype(context(*tasks[0]).dpSettings)>;
using TDPTraits = typename TDPSettings::TTraits;
using TDPProfile = DPProfile_<typename TDPTraits::TAlgorithmType,
typename TDPTraits::TGapType,
typename TDPTraits::TTracebackType,
Parallel>;
using TSimdScoutTrait = SimdAlignVariableLengthTraits<TSimdVec,
decltype(depSetH),
decltype(depSetV),
TDPProfile>;
using TScoutState = DPScoutState_<DPTiled<TSimdBufferH, Default, SimdAlignVariableLength<TSimdScoutTrait>>>;
String<size_t> lengthsH;
String<size_t> lengthsV;
TScoutState scoutState(bufferH, bufferV);
_prepareSimdAlignment(stringSimdH, stringSimdV, depSetH, depSetV, lengthsH, lengthsV, scoutState);
using TScoutSpec = typename ScoutSpecForAlignmentAlgorithm_<typename TExecTraits::TAlgorithmType, TScoutState>::Type;
using TDPScout = DPScout_<TDPCell, TScoutSpec>;
TDPScout dpScout(scoutState);
computeTile(cache, dpScout, stringSimdH, stringSimdV, scoringScheme, context(*tasks[0]).dpSettings);
// We want to get the state here from the scout.
for (size_t pos = 0; pos < length(tasks); ++pos)
{
auto & task = *tasks[pos];
if (AlgorithmProperty<typename TExecTraits::TAlgorithmType>::isTrackingEnabled(task))
{
// TODO(rrahn): Implement the interface.
// TODO(rrahn): Make it a member function of a policy so that we don't have to implement the specifics here
_setSimdLane(dpScout, pos);
auto & taskContext = context(task);
updateMax(intermediate(dpLocal, taskContext.alignmentId),
{maxScoreAt(dpScout) + offset[pos], 0u},
column(task),
row(task));
}
}
}
}
#endif // SEQAN_SIMD_ENABLED
} // namespace impl
} // namespace seqan
#endif // #ifndef INCLUDE_SEQAN_ALIGN_PARALLEL_WAVEFRONT_TASK_UTIL_H_
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