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// ==========================================================================
// SeqAn - The Library for Sequence Analysis
// ==========================================================================
// Copyright (c) 2006-2018, Knut Reinert, FU Berlin
// All rights reserved.
//
// Redistribution and use in source and binary forms, with or without
// modification, are permitted provided that the following conditions are met:
//
// * Redistributions of source code must retain the above copyright
// notice, this list of conditions and the following disclaimer.
// * Redistributions in binary form must reproduce the above copyright
// notice, this list of conditions and the following disclaimer in the
// documentation and/or other materials provided with the distribution.
// * Neither the name of Knut Reinert or the FU Berlin nor the names of
// its contributors may be used to endorse or promote products derived
// from this software without specific prior written permission.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
// AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
// IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
// ARE DISCLAIMED. IN NO EVENT SHALL KNUT REINERT OR THE FU BERLIN BE LIABLE
// FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
// DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
// SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
// CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
// LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
// OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH
// DAMAGE.
//
// ==========================================================================
// TODO(holtgrew): Move this away?
#ifndef SEQAN_HEADER_GRAPH_ALGORITHM_LIS_HIS_H
#define SEQAN_HEADER_GRAPH_ALGORITHM_LIS_HIS_H
namespace seqan
{
struct Lcs_;
typedef Tag<Lcs_> Lcs;
//////////////////////////////////////////////////////////////////////////////
// LIS: Longest Increasing Subsequence
//////////////////////////////////////////////////////////////////////////////
//////////////////////////////////////////////////////////////////////////////
template<typename TSortedSequence, typename TKey>
inline typename TSortedSequence::const_iterator
_previousInSortedSequence(TSortedSequence const& list, TKey const key) {
typedef typename TSortedSequence::const_iterator TSortedSequenceIter;
TSortedSequenceIter a_k_it = list.lower_bound(key);
// Now we need to move one to the front
if (a_k_it != list.end()) {
// If we are at the beginning, no predecessor
if (a_k_it == list.begin()) a_k_it = list.end();
else --a_k_it;
} else {
// If we are at the end, the predecessor is the last element of the list
TSortedSequenceIter tmp = list.begin();
if (tmp != list.end()) {
do {
a_k_it = tmp;
} while(++tmp != list.end());
}
}
return a_k_it;
}
//////////////////////////////////////////////////////////////////////////////
template<typename TSortedSequence, typename TIterator>
inline typename TSortedSequence::const_iterator
_nextInSortedSequence(TSortedSequence const& list, TIterator const& prev) {
typedef typename TSortedSequence::const_iterator TSortedSequenceIter;
TSortedSequenceIter b_l_it;
if (prev == list.end()) b_l_it = list.begin();
else b_l_it = list.upper_bound(*prev);
return b_l_it;
}
//////////////////////////////////////////////////////////////////////////////
/*!
* @fn longestIncreasingSubsequence
* @headerfile <seqan/graph_algorithms.h>
* @brief Computes the longest increasing subsequence.
*
* @signature void longestIncreasingSubsequence(str, pos);
*
* @param[in] str An arbitrary @link ContainerConcept @endlink object.
* @param[out] pos A String with the positions that belong to the longest increasing subsequence.
*
* @section Remarks
*
* The last position in <tt>pos</tt> indicates the first element in the longets increasing subsequence.
*
* @section Example
*
* @include demos/dox/graph_algorithms/longest_increasing_subsequence.cpp
*
* @code{.console}
* 5,3,4,9,6,2,1,8,7,10,
* Lis:
* 3,4,6,7,10,
* @endcode
*
* @see heaviestIncreasingSubsequence
* @see longestCommonSubsequence
*/
template<typename TString, typename TPositions>
inline void
longestIncreasingSubsequence(TString const& str, TPositions& pos) {
// The list of decreasing covers, only the smallest number must be remembered
// See Gusfield
typedef std::pair<typename Value<TString>::Type, typename Position<TPositions>::Type> TKey;
typedef std::set<TKey, std::less<TKey> > TSortedSequence;
typedef typename TSortedSequence::const_iterator TSortedSequenceIter;
TSortedSequence list;
// The trace-back graph
typedef Graph<Directed<void, WithoutEdgeId> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
TGraph g;
// Walk through the sequence and build the decreasing covers
typedef typename Iterator<TString const, Rooted>::Type TStringIter;
TStringIter endIt = end(str);
for(TStringIter it = begin(str); it != endIt; ++it) {
// Get previous element
TSortedSequenceIter a_k_it = _previousInSortedSequence(list, std::make_pair(*it, 0));
// Get next element
TSortedSequenceIter b_l_it = _nextInSortedSequence(list, a_k_it);
// Delete from list
if (b_l_it != list.end()) list.erase(*b_l_it);
// Insert new list element
list.insert(std::make_pair(*it, position(it)));
// Create the corresponding node
// Note: The VertexDescriptor == position(it)
addVertex(g);
// Connect to predecessor
if (a_k_it != list.end()) addEdge(g, (TVertexDescriptor) position(it), (TVertexDescriptor) a_k_it->second);
}
// Trace-back
if (list.rbegin() == list.rend()) return;
else {
// Start with the maximal position in the list == Vertex Descriptor
TVertexDescriptor v = list.rbegin()->second;
while (true) {
appendValue(pos, v, Generous());
if (g.data_vertex[v]) v = (*g.data_vertex[v]).data_target;
else break;
}
}
}
//////////////////////////////////////////////////////////////////////////////
// LCS: Longest Common Subsequence
//////////////////////////////////////////////////////////////////////////////
//////////////////////////////////////////////////////////////////////////////
/*!
* @fn longestCommonSubsequence
* @headerfile <seqan/graph_algorithms.h>
* @brief Computes the longest common subsequence.
*
* @signature void longestCommonSubsequence(str1, str2, nSize, pos);
*
* @param[in] str1 An arbitrary @link ContainerConcept @endlink object.
* @param[in] str2 A second arbitrary @link ContainerConcept @endlink object.
* @param[in] nSize The neighbourhood size to use.
* @param[out] pos A String with pairs of positions that indicate the longest common subsequence.
*
* @section Example
*
* @include demos/dox/graph_algorithms/longest_common_subsequence.cpp
*
* @code{.console}
* Score = 3
* Alignment matrix:
* 0 .
* aba--cx-
* || |
* -baabc-a
* @endcode
*
* @see heaviestIncreasingSubsequence
* @see longestIncreasingSubsequence
*/
template<typename TString1, typename TString2, typename TNeighborhoodSize, typename TFinalPos>
inline void
longestCommonSubsequence(TString1 const& str1,
TString2 const& str2,
TNeighborhoodSize nSize,
TFinalPos& pos)
{
typedef typename Value<TString1>::Type TValue;
typedef typename Size<TString1>::Type TSize;
typedef typename Position<TString1>::Type TPos;
TSize alphabet_size = ValueSize<TValue>::VALUE;
// The occurrences of each letter in the second string
typedef String<TPos> TPositions;
String<TPositions> occ;
resize(occ, alphabet_size, TPositions());
typedef typename Iterator<TString2 const, Standard>::Type TStringIter;
TStringIter itStr2 = begin(str2, Standard());
TStringIter endItStr2 = end(str2, Standard());
TPos current_pos = 0;
for(; itStr2 != endItStr2; ++itStr2, ++current_pos) appendValue(occ[ordValue(*itStr2)], current_pos, Generous());
// Build the combined string
String<TPos> finalSeq;
String<TPos> mapping;
TStringIter itStr1 = begin(str1, Standard());
TStringIter endItStr1 = end(str1, Standard());
current_pos = 0;
TPos diff = 0;
for(; itStr1 != endItStr1; ++itStr1, ++current_pos) {
TPositions& current_occ = occ[ordValue(*itStr1)];
for(int i = length(current_occ)-1; i>=0; --i) {
// Do we have a neighborhood
diff = (current_pos < current_occ[i]) ? current_occ[i] - current_pos : current_pos - current_occ[i];
if (diff > (TPos) nSize) continue;
appendValue(finalSeq, current_occ[i], Generous());
appendValue(mapping, current_pos, Generous());
}
}
// Call longest increasing subsequence
typedef String<TSize> TResult;
TResult result;
longestIncreasingSubsequence(finalSeq, result);
// Insert the common pairs
typedef typename Iterator<TResult, Standard>::Type TResultIter;
TResultIter itResult = begin(result, Standard());
TResultIter endResult = end(result, Standard());
for(; itResult != endResult; ++itResult)
appendValue(pos, std::make_pair(mapping[*itResult], finalSeq[*itResult]), Generous());
}
//////////////////////////////////////////////////////////////////////////////
template<typename TAlign, typename TStringSet>
inline int
globalAlignment(TAlign& align,
TStringSet const& str,
Lcs)
{
typedef typename Id<TStringSet>::Type TId;
typedef typename Size<TStringSet>::Type TSize;
TId id1 = positionToId(str, 0);
TId id2 = positionToId(str, 1);
// Lcs between first and second string
String<std::pair<TSize, TSize> > pos1;
longestCommonSubsequence(str[0], str[1], 100, pos1);
//longestCommonSubsequence(str[0], str[1], 800, pos1);
// Extend the matches as long as possible
TSize oldI = 0;
TSize oldJ = 0;
TSize totalLen = 0;
if (length(pos1)) {
TSize lenMatch = 1;
int last = length(pos1)-1;
TSize iBegin = pos1[last].first;
TSize jBegin = pos1[last].second;
for(int z = last - 1; z>=0; --z) {
if ((pos1[z].first == pos1[z+1].first + 1) &&
(pos1[z].second == pos1[z+1].second + 1))
{
++lenMatch;
} else {
if (oldI < iBegin) _alignTracePrint(align, str[0], str[1], id1, oldI, id2, (TSize) 0, (TSize) iBegin - oldI, 1);
if (oldJ < jBegin) _alignTracePrint(align, str[0], str[1], id1, (TSize) 0, id2, oldJ, (TSize) jBegin - oldJ, 2);
oldI = iBegin + lenMatch;
oldJ = jBegin + lenMatch;
_alignTracePrint(align, str[0], str[1], id1, iBegin, id2, jBegin, lenMatch, 0);
totalLen += lenMatch;
lenMatch = 1;
iBegin = pos1[z].first;
jBegin = pos1[z].second;
}
}
// Process last match
if (oldI < iBegin) _alignTracePrint(align, str[0], str[1], id1, oldI, id2, (TSize) 0, (TSize) iBegin - oldI, 1);
if (oldJ < jBegin) _alignTracePrint(align, str[0], str[1], id1, (TSize) 0, id2, oldJ, (TSize) jBegin - oldJ, 2);
oldI = iBegin + lenMatch;
oldJ = jBegin + lenMatch;
_alignTracePrint(align, str[0], str[1], id1, iBegin, id2, jBegin, lenMatch, 0);
totalLen += lenMatch;
}
// Process left overs
if (oldI < length(str[0])) _alignTracePrint(align, str[0], str[1], id1, oldI, id2, (TSize) 0, (TSize) length(str[0]) - oldI, 1);
if (oldJ < length(str[1])) _alignTracePrint(align, str[0], str[1], id1, (TSize) 0, id2, oldJ, (TSize) length(str[1]) - oldJ, 2);
return (int) totalLen;
}
//////////////////////////////////////////////////////////////////////////////
// HIS: Heaviest Increasing Subsequence
//////////////////////////////////////////////////////////////////////////////
//////////////////////////////////////////////////////////////////////////////
/*!
* @fn heaviestIncreasingSubsequence
* @headerfile <seqan/graph_algorithms.h>
* @brief Computes the heaviest increasing subseqnece.
*
* @signature void heaviestIncreasingSubsequence(str, weights, pos);
*
* @param[in] str An arbitrary @link ContainerConcept @endlink object.
* @param[in] weights A String with a weight for each position in the string.
* @param[out] pos A String with positions that indicate the members of the heaviest increasing subsequence.
*
* @section Remarks
*
* The last position in pos indicates the first member of the heviest increasing subsequence. Note that only members
* that contribute a weight are selected, that is, positions with associated 0 weights are ignored.
*
* @section Example
*
* @include demos/dox/graph_algorithms/heaviest_increasing_subsequence.cpp
*
* @code{.console}
* z(Weight=1),e(Weight=1),i(Weight=10),t(Weight=1),g(Weight=1),e(Weight=1),i(Weight=1),s(Weight=1),t(Weight=1),
* His:
* e,i,s,t,(Weight=13)
* @endcode
*
* @see longestCommonSubsequence
* @see longestIncreasingSubsequence
*/
template<typename TString, typename TWeightMap, typename TPositions>
inline typename Value<TWeightMap>::Type
heaviestIncreasingSubsequence(TString const& str,
TWeightMap const& weights,
TPositions& pos)
{
typedef typename Size<TString>::Type TSize;
typedef typename Value<TString>::Type TValue;
typedef typename Value<TPositions>::Type TPos;
typedef typename Value<TWeightMap>::Type TWeight;
// The list of decreasing covers, only the smallest element of each member must be remembered
typedef std::pair<TValue, std::pair<TWeight, TPos> > TKey;
typedef std::set<TKey, std::less<TKey> > TSortedSequence;
typedef typename TSortedSequence::const_iterator TSortedSequenceIter;
TSortedSequence list;
// The trace-back graph
typedef Graph<Directed<void, WithoutEdgeId> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
TGraph g;
// Walk through the sequence and build the decreasing covers
typedef typename Iterator<TString const, Standard>::Type TStringIter;
TStringIter it = begin(str, Standard());
TStringIter endIt = end(str, Standard());
TSize pos_of_iterator = 0;
TWeight w = 0;
for(; it != endIt; ++it, ++pos_of_iterator) {
w = weights[pos_of_iterator];
// Letters that do not contribute a weight (e.g., w = 0) are excluded!
// Weights must increase!
if (w == 0) {
addVertex(g); // Note: The vertex id corresponds to the position
continue;
}
// Get previous element
TSortedSequenceIter a_k_it = _previousInSortedSequence(list, std::make_pair(*it, std::make_pair(0, 0)));
// Get next element
TSortedSequenceIter b_l_it = _nextInSortedSequence(list, a_k_it);
// Determine new weight
if (a_k_it != list.end()) w += a_k_it->second.first;
// Delete from list
while ((b_l_it != list.end()) &&
(w >= b_l_it->second.first)) {
TSortedSequenceIter tmp = b_l_it;
b_l_it = _nextInSortedSequence(list, b_l_it);
list.erase(*tmp);
}
// Insert new list element
if ((b_l_it == list.end()) ||
(*it < b_l_it->first)) {
list.insert(std::make_pair(*it, std::make_pair(w, pos_of_iterator)));
}
// Create the corresponding node, pos_of_iterator == Vertex Descriptor
addVertex(g);
// Connect to predecessor
if (a_k_it != list.end()) addEdge(g, (TVertexDescriptor) pos_of_iterator, (TVertexDescriptor) a_k_it->second.second);
}
// Trace-back
w = 0;
if (list.rbegin() == list.rend()) return 0;
else {
// Last vertex is end of heaviest increasing subsequence
TVertexDescriptor v = list.rbegin()->second.second;
while (true) {
appendValue(pos, v, Generous());
w+=weights[v];
if (g.data_vertex[v]) v = (*g.data_vertex[v]).data_target;
else break;
}
}
return w;
}
}// namespace seqan
#endif //#ifndef SEQAN_HEADER_...
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