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// ==========================================================================
// SeqAn - The Library for Sequence Analysis
// ==========================================================================
// Copyright (c) 2006-2026, Knut Reinert, FU Berlin
// All rights reserved.
//
// Redistribution and use in source and binary forms, with or without
// modification, are permitted provided that the following conditions are met:
//
// * Redistributions of source code must retain the above copyright
// notice, this list of conditions and the following disclaimer.
// * Redistributions in binary form must reproduce the above copyright
// notice, this list of conditions and the following disclaimer in the
// documentation and/or other materials provided with the distribution.
// * Neither the name of Knut Reinert or the FU Berlin nor the names of
// its contributors may be used to endorse or promote products derived
// from this software without specific prior written permission.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
// AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
// IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
// ARE DISCLAIMED. IN NO EVENT SHALL KNUT REINERT OR THE FU BERLIN BE LIABLE
// FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
// DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
// SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
// CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
// LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
// OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH
// DAMAGE.
//
// ==========================================================================
// Author: Manuel Holtgrewe <manuel.holtgrewe@fu-berlin.de>
// ==========================================================================
// Reading of BED from files.
// ==========================================================================
#ifndef INCLUDE_SEQAN_BED_IO_READ_BED_H_
#define INCLUDE_SEQAN_BED_IO_READ_BED_H_
#include <seqan/stream.h>
namespace seqan2 {
// ============================================================================
// Tags, Classes, Enums
// ============================================================================
struct Bed_;
typedef Tag<Bed_> Bed;
// ============================================================================
// Metafunctions
// ============================================================================
// ----------------------------------------------------------------------------
// Class MagicHeader
// ----------------------------------------------------------------------------
template <typename T>
struct MagicHeader<Bed, T> :
public MagicHeader<Nothing, T> {};
// ----------------------------------------------------------------------------
// Class FileExtensions
// ----------------------------------------------------------------------------
template <typename T>
struct FileExtensions<Bed, T>
{
static char const * VALUE[1]; // default is one extension
};
template <typename T>
char const * FileExtensions<Bed, T>::VALUE[1] =
{
".bed" // default output extension
};
// ============================================================================
// Functions
// ============================================================================
// ----------------------------------------------------------------------------
// Function readRecord() [BedRecord]
// ----------------------------------------------------------------------------
// We have a helper function _readBedRecordNoData() that has various
// overloads. The one for Bed$N$ calls the one with Bed$N-1$.
// Helper function that reads first three fields of BED record.
// NoData means the the member data (for the columns not read) is not
// filled.
template <typename TForwardIter>
inline void
_readBedRecordNoData(BedRecord<Bed3> & record,
TForwardIter & iter,
CharString & buffer)
{
// Read CHROM.
readUntil(record.ref, iter, OrFunctor<IsTab, AssertFunctor<NotFunctor<IsNewline>, ParseError, Bed> >());
if (record.ref == "track")
{
skipLine(iter);
return;
}
skipOne(iter);
// Read START.
// TODO(singer): Realy int32_t for a position ???
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, AssertFunctor<NotFunctor<IsNewline>, ParseError, Bed> >());
// NB: in contrast to many other text-based formats, UCSC BED uses 0-based and not 1-based coordinates.
record.beginPos = lexicalCast<int32_t>(buffer);
skipOne(iter);
// Read END.
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, IsNewline>());
record.endPos = lexicalCast<int32_t>(buffer);
// Go over tab if any.
if (!atEnd(iter) && IsTab()(value(iter)))
skipOne(iter);
}
// Read first four fields without data.
template <typename TForwardIter>
inline void
_readBedRecordNoData(BedRecord<Bed4> & record,
TForwardIter & iter,
CharString & buffer)
{
// Read first three fields.
_readBedRecordNoData(static_cast<BedRecord<Bed3> &>(record), iter, buffer);
// Read NAME.
readUntil(record.name, iter, OrFunctor<IsTab, IsNewline>());
// Go over tab if any.
if (!atEnd(iter) && IsTab()(value(iter)))
skipOne(iter);
}
// Read first five fields without data.
template <typename TForwardIter>
inline void
_readBedRecordNoData(BedRecord<Bed5> & record,
TForwardIter & iter,
CharString & buffer)
{
// Read first four fields.
_readBedRecordNoData(static_cast<BedRecord<Bed4 > &>(record), iter, buffer);
// Read SCORE.
readUntil(record.score, iter, OrFunctor<IsTab, IsNewline>());
// Go over tab if any.
if (!atEnd(iter) && IsTab()(value(iter)))
skipOne(iter);
}
// Read first six fields without data.
template <typename TForwardIter>
inline void
_readBedRecordNoData(BedRecord<Bed6> & record,
TForwardIter & iter,
CharString & buffer)
{
// Read first three fields.
_readBedRecordNoData(static_cast<BedRecord<Bed5 > &>(record), iter, buffer);
// Read STRAND.
record.strand = value(iter);
skipOne(iter, OrFunctor<OrFunctor<EqualsChar<'.'>, EqualsChar<'+'> >, EqualsChar<'-'> >());
// Go over tab if any.
if (!atEnd(iter) && !IsNewline()(value(iter)))
skipOne(iter);
}
// Read first twelve fields without data.
template <typename TForwardIter>
inline void
_readBedRecordNoData(BedRecord<Bed12> & record,
TForwardIter & iter,
CharString & buffer)
{
typedef AssertFunctor<NotFunctor<IsNewline>, ParseError, Bed> AssertNoNewline;
// Read first three fields.
_readBedRecordNoData(static_cast<BedRecord<Bed6 > &>(record), iter, buffer);
// Read THICK BEGIN
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, AssertNoNewline>());
record.thickBegin = lexicalCast<int32_t>(buffer);
skipOne(iter);
// Read THICK END
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, AssertNoNewline>());
record.thickEnd = lexicalCast<int32_t>(buffer);
skipOne(iter);
// Read ITEM RGB
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, OrFunctor<EqualsChar<','>, AssertNoNewline> >());
record.itemRgb.red = lexicalCast<int32_t>(buffer);
if (value(iter) == ',')
{
skipOne(iter);
clear(buffer);
readUntil(buffer, iter, OrFunctor<EqualsChar<','>, AssertNoNewline>());
record.itemRgb.green = lexicalCast<int32_t>(buffer);
skipOne(iter);
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, AssertNoNewline>());
record.itemRgb.blue = lexicalCast<int32_t>(buffer);
skipOne(iter);
}
else if (value(iter) == '\t' && record.itemRgb.red == 0) // allow a single '0' value for 0,0,0
{
skipOne(iter);
record.itemRgb.green = 0;
record.itemRgb.blue = 0;
}
else
{
throw ParseError("While parsing field 9 (itemRGB) in BED12 file: "
"value must be either 0 or a list of three integer values r,g,b.");
}
// Read BLOCK COUNT
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, AssertNoNewline>());
record.blockCount = lexicalCast<int32_t>(buffer);
skipOne(iter);
// READ BLOCK SIZES
for (int i = 0; i < record.blockCount - 1; ++i)
{
clear(buffer);
readUntil(buffer, iter, OrFunctor<EqualsChar<','>, AssertNoNewline>());
appendValue(record.blockSizes, lexicalCast<int>(buffer));
skipOne(iter);
}
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, OrFunctor<EqualsChar<','>, AssertNoNewline> >());
appendValue(record.blockSizes, lexicalCast<int>(buffer));
if (value(iter) == ',') // allow trailing comma at the end of the list
skipOne(iter);
skipOne(iter);
// READ BLOCK STARTS
for (int i = 0; i < record.blockCount - 1; ++i)
{
clear(buffer);
readUntil(buffer, iter, OrFunctor<EqualsChar<','>, AssertNoNewline>());
appendValue(record.blockBegins, lexicalCast<int>(buffer));
skipOne(iter);
}
clear(buffer);
readUntil(buffer, iter, OrFunctor<IsTab, OrFunctor<EqualsChar<','>, IsNewline> >());
appendValue(record.blockBegins, lexicalCast<int>(buffer));
if (!atEnd(iter) && value(iter) == ',') // allow trailing comma at the end of the list
skipOne(iter);
if (!atEnd(iter) && value(iter) == '\t')
skipOne(iter);
// DO NOT skip line here, because the rest of the line (empty or not) is written
// into record.data in the readRecord function below.
}
// The front-end function automatically calls the correct overload of
// _readBedRecordNoData through the type of record.
template <typename TSpec, typename TForwardIter>
inline void
readRecord(BedRecord<TSpec> & record,
CharString & buffer,
TForwardIter & iter,
Bed const & /*tag*/)
{
clear(record);
_readBedRecordNoData(record, iter, buffer);
readLine(record.data, iter);
}
} // namespace seqan2
#endif // #ifndef INCLUDE_SEQAN_BED_IO_READ_BED_H_
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