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// ==========================================================================
// SeqAn - The Library for Sequence Analysis
// ==========================================================================
// Copyright (c) 2006-2026, Knut Reinert, FU Berlin
// All rights reserved.
//
// Redistribution and use in source and binary forms, with or without
// modification, are permitted provided that the following conditions are met:
//
// * Redistributions of source code must retain the above copyright
// notice, this list of conditions and the following disclaimer.
// * Redistributions in binary form must reproduce the above copyright
// notice, this list of conditions and the following disclaimer in the
// documentation and/or other materials provided with the distribution.
// * Neither the name of Knut Reinert or the FU Berlin nor the names of
// its contributors may be used to endorse or promote products derived
// from this software without specific prior written permission.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
// AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
// IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
// ARE DISCLAIMED. IN NO EVENT SHALL KNUT REINERT OR THE FU BERLIN BE LIABLE
// FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
// DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
// SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
// CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
// LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
// OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH
// DAMAGE.
//
// ==========================================================================
// External / STL
#include <sstream>
// SeqAn Includes
#include <seqan/basic.h>
#ifndef SEQAN_HEADER_TEST_GRAPH_IMPL_ALIGN_H
#define SEQAN_HEADER_TEST_GRAPH_IMPL_ALIGN_H
namespace seqan2 {
//////////////////////////////////////////////////////////////////////////////
// Alignment without edge weights
SEQAN_DEFINE_TEST(Test_Refinement_AlignmentGraphNoEdgeWeights)
{
typedef String<Dna> TString;
typedef StringSet<TString, Dependent<> > TStringSet;
typedef Graph<Alignment<TStringSet, void> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
typedef EdgeDescriptor<TGraph>::Type TEdgeDescriptor;
typedef Id<TStringSet>::Type TId;
TVertexDescriptor nilVertex = getNil<TVertexDescriptor>();
// Difference between Owner and Dependent
typedef StringSet<TString, Owner<> > TOwnerStringSet;
TStringSet str;
TOwnerStringSet ownStr;
TString str0("acaagtaacataaaaaaaaaaaaaaaacccccccccttttttttaaaaa");
TId id0 = assignValueById(str, str0);
appendValue(ownStr, str0);
TString str1("cccaaagggtttttccccccccccccttttttttttaaaaaaagggggggg");
TId id1 = assignValueById(str, str1);
appendValue(ownStr, str1);
TString str2("cacatgtaatcatgggggggggccccccttttaaaaaaaaaaatttt");
TId id2 = assignValueById(str, str2);
appendValue(ownStr, str2);
// Check that the graph makes a dependent StringSet
TGraph alwaysDependStringSet(ownStr);
SEQAN_ASSERT_EQ(length(value(stringSet(alwaysDependStringSet), 0)), length(str0));
clear(alwaysDependStringSet);
SEQAN_ASSERT_EQ(length(value(ownStr, 0)), length(str0));
assignStringSet(alwaysDependStringSet, ownStr);
SEQAN_ASSERT_EQ(length(value(stringSet(alwaysDependStringSet), 0)), length(str0));
clear(ownStr);
SEQAN_ASSERT(empty(ownStr));
TGraph g(str);
SEQAN_ASSERT_EQ(getStringSet(g)[0], str0);
SEQAN_ASSERT_EQ(getStringSet(g)[1], str1);
SEQAN_ASSERT_EQ(stringSet(g)[2], str2);
assignStringSet(g, str);
SEQAN_ASSERT_EQ(getStringSet(g)[0], str0);
SEQAN_ASSERT_EQ(getStringSet(g)[1], str1);
SEQAN_ASSERT_EQ(stringSet(g)[2], str2);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
SEQAN_ASSERT_EQ(numVertices(g), 0u);
SEQAN_ASSERT(empty(g));
TVertexDescriptor v0 = addVertex(g, id1, 0, 2);
SEQAN_ASSERT_EQ(v0, 0u);
SEQAN_ASSERT_EQ(outDegree(g, v0), 0u);
SEQAN_ASSERT_EQ(inDegree(g, 0), 0u);
SEQAN_ASSERT_EQ(degree(g, 0), 0u);
SEQAN_ASSERT_EQ(numVertices(g), 1u);
SEQAN_ASSERT(!empty(g));
SEQAN_ASSERT_EQ(sequenceId(g, v0), id1);
SEQAN_ASSERT_EQ(label(g, v0), "cc");
SEQAN_ASSERT_EQ(fragmentBegin(g, v0), 0u);
SEQAN_ASSERT_EQ(fragmentLength(g, v0), 2u);
SEQAN_ASSERT_EQ(findVertex(g, id1, 0), v0);
SEQAN_ASSERT_EQ(findVertex(g, id1, 1), v0);
SEQAN_ASSERT_EQ(findVertex(g, id1, 2), nilVertex);
TVertexDescriptor v1 = addVertex(g, id2, 0, 5);
TEdgeDescriptor e = addEdge(g,0,1);
SEQAN_ASSERT_EQ(_getVertexString(g)[0], e);
SEQAN_ASSERT_EQ(getIdUpperBound(_getVertexIdManager(g)), 2u);
SEQAN_ASSERT_EQ(getIdUpperBound(_getEdgeIdManager(g)), 1u);
SEQAN_ASSERT_EQ(v1, 1u);
SEQAN_ASSERT_EQ(numVertices(g), 2u);
SEQAN_ASSERT_EQ(targetVertex(g, e), 1u);
SEQAN_ASSERT_EQ(sourceVertex(g, e), 0u);
SEQAN_ASSERT_EQ(numEdges(g), 1u);
SEQAN_ASSERT_EQ(outDegree(g, v0), 1u);
SEQAN_ASSERT_EQ(inDegree(g, 1), 1u);
SEQAN_ASSERT_EQ(inDegree(g, 0), 1u);
SEQAN_ASSERT_EQ(degree(g, 0), 1u);
SEQAN_ASSERT_EQ(findVertex(g, id2, 0), v1);
SEQAN_ASSERT_EQ(findVertex(g, id2, 1), v1);
SEQAN_ASSERT_EQ(findVertex(g, id2, 4), v1);
SEQAN_ASSERT_EQ(findVertex(g, id2, 5), nilVertex);
// Add more vertices and edges
addVertex(g, id1, 10, 20); // 2
SEQAN_ASSERT_EQ(findVertex(g, id1, 0), v0);
SEQAN_ASSERT_EQ(findVertex(g, id1, 1), v0);
SEQAN_ASSERT_EQ(findVertex(g, id1, 2), nilVertex);
SEQAN_ASSERT_EQ(findVertex(g, id1, 10), 2u);
SEQAN_ASSERT_EQ(findVertex(g, id1, 19), 2u);
SEQAN_ASSERT_EQ(findVertex(g, id1, 30), nilVertex);
TVertexDescriptor v3 = addVertex(g, id2, 5, 2); // 3
addVertex(g, id1, 7, 3); // 4
addEdge(g, 3, 4);
TEdgeDescriptor my_edge = addEdge(g, 3, 1);
addEdge(g, 3, 0);
SEQAN_ASSERT_EQ(v3, 3u);
SEQAN_ASSERT_EQ(numVertices(g), 5u);
SEQAN_ASSERT_EQ(targetVertex(g, my_edge), 3u);
SEQAN_ASSERT_EQ(sourceVertex(g, my_edge), 1u);
SEQAN_ASSERT_EQ(numEdges(g), 4u);
SEQAN_ASSERT_EQ(outDegree(g, v3), 3u);
SEQAN_ASSERT_EQ(inDegree(g, v3), 3u);
SEQAN_ASSERT_EQ(degree(g, v3), 3u);
// Remove edges
removeEdge(g, 3, 1);
removeEdge(g, 0, 1);
SEQAN_ASSERT_EQ(numEdges(g), 2u);
// Remove vertices
addVertex(g, id2, 14, 4); // 5
addEdge(g, 5, 2);
addEdge(g, 2, 3);
addEdge(g, 1, 3);
addEdge(g, 1, 4);
SEQAN_ASSERT_EQ(outDegree(g, 3), 4u);
SEQAN_ASSERT_EQ(outDegree(g, 4), 2u);
removeVertex(g, v3);
SEQAN_ASSERT_EQ(outDegree(g, 4), 1u);
SEQAN_ASSERT_EQ(outDegree(g, 0), 0u);
SEQAN_ASSERT_EQ(numVertices(g), 5u);
SEQAN_ASSERT_EQ(numEdges(g), 2u);
// Clear graph
clearEdges(g);
SEQAN_ASSERT_EQ(numVertices(g), 5u);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
addEdge(g, 2, 0);
addEdge(g, 4, 1);
clearVertices(g);
SEQAN_ASSERT_EQ(numVertices(g), 0u);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
addVertex(g, id1, 0, 1); addVertex(g, id1, 1, 1); addVertex(g, id1, 2, 1);
addVertex(g, id1, 3, 1); addVertex(g, id1, 4, 1);
addEdge(g, 2, 0);
addEdge(g, 4, 1);
clear(g);
assignStringSet(g, str);
SEQAN_ASSERT_EQ(numVertices(g), 0u);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
addVertex(g, id1, 0, 1); addVertex(g, id1, 1, 1); addVertex(g, id1, 2, 1);
addVertex(g, id1, 3, 1); addVertex(g, id1, 4, 1);
addEdge(g, 2, 0);
addEdge(g, 4, 1);
addEdge(g, 4, 2);
removeVertex(g, 3);
SEQAN_ASSERT_EQ(numVertices(g), 4u);
SEQAN_ASSERT_EQ(numEdges(g), 3u);
SEQAN_ASSERT_EQ(outDegree(g, 4), 2u);
SEQAN_ASSERT_EQ(inDegree(g, 4), 2u);
// Transpose
transpose(g);
SEQAN_ASSERT_EQ(numVertices(g), 4u);
SEQAN_ASSERT_EQ(numEdges(g), 3u);
SEQAN_ASSERT_EQ(outDegree(g, 4), 2u);
SEQAN_ASSERT_EQ(inDegree(g, 4), 2u);
TGraph g_copy(g);
SEQAN_ASSERT_EQ(numVertices(g_copy), 4u);
SEQAN_ASSERT_EQ(numEdges(g_copy), 3u);
SEQAN_ASSERT_EQ(outDegree(g_copy, 4), 2u);
SEQAN_ASSERT_EQ(inDegree(g_copy, 4), 2u);
addVertex(g_copy, id0, 0, 3);
addEdge(g_copy, 3, 0);
g_copy = g;
SEQAN_ASSERT_EQ(numVertices(g_copy), 4u);
SEQAN_ASSERT_EQ(numEdges(g_copy), 3u);
SEQAN_ASSERT_EQ(outDegree(g_copy, 4), 2u);
SEQAN_ASSERT_EQ(inDegree(g_copy, 4), 2u);
//Copies the graph and transposes just the copy
transpose(g, g_copy); // g does not change!
SEQAN_ASSERT_EQ(numVertices(g_copy), 4u);
SEQAN_ASSERT_EQ(numEdges(g_copy), 3u);
SEQAN_ASSERT_EQ(outDegree(g_copy, 4), 2u);
SEQAN_ASSERT_EQ(inDegree(g_copy, 4), 2u);
// Adjacency matrix
String<unsigned int> mat;
getAdjacencyMatrix(g, mat);
unsigned int len = (unsigned int) std::sqrt((double) length(mat));
SEQAN_ASSERT_EQ(getValue(mat, 0 * len + 2), 1u);
SEQAN_ASSERT_EQ(getValue(mat, 3 * len + 2), 0u);
SEQAN_ASSERT_EQ(getValue(mat, 0 * len + 2), getValue(mat, 2 * len + 0));
SEQAN_ASSERT_EQ(getValue(mat, 1 * len + 4), getValue(mat, 4 * len + 1));
SEQAN_ASSERT_EQ(getValue(mat, 2 * len + 4), getValue(mat, 4 * len + 2));
// Vertex Adjacency vectors
String<unsigned int> vectIn, vectOut;
getVertexAdjacencyVector(vectIn, vectOut, g, 2u);
SEQAN_ASSERT(length(vectIn) == 2);
SEQAN_ASSERT(length(vectOut) == 2);
SEQAN_ASSERT(vectIn[0] == 4);
SEQAN_ASSERT(vectIn[1] == 0);
SEQAN_ASSERT(vectOut[0] == 4);
SEQAN_ASSERT(vectOut[1] == 0);
}
//////////////////////////////////////////////////////////////////////////////
// Alignments with edge weights
SEQAN_DEFINE_TEST(Test_Refinement_AlignmentGraphEdgeWeights)
{
typedef String<Dna> TString;
typedef StringSet<TString, Dependent<> > TStringSet;
typedef Id<TStringSet>::Type TId;
typedef Graph<Alignment<TStringSet> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
typedef EdgeDescriptor<TGraph>::Type TEdgeDescriptor;
TStringSet str;
TString str0("acaagtaacataaaaaaaaaaaaaaaacccccccccttttttttaaaaa");
appendValue(str, str0);
TString str1("cccaaagggtttttccccccccccccttttttttttaaaaaaagggggggg");
TId id1 = assignValueById(str, str1);
TString str2("cacatgtaatcatgggggggggccccccttttaaaaaaaaaaatttt");
TId id2 = assignValueById(str, str2);
TGraph g(str);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
SEQAN_ASSERT_EQ(numVertices(g), 0u);
SEQAN_ASSERT(empty(g));
TVertexDescriptor v0 = addVertex(g, id1, 0, 2);
TVertexDescriptor v1 = addVertex(g, id2, 0, 5);
SEQAN_ASSERT_EQ(v0, 0u);
SEQAN_ASSERT_EQ(v1, 1u);
TEdgeDescriptor e1 = addEdge(g, 0, 1, 100);
SEQAN_ASSERT_EQ(getCargo(e1), 100u);
SEQAN_ASSERT_EQ(numEdges(g), 1u);
removeEdge(g, e1);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
e1 = addEdge(g, 0, 1, 1005);
SEQAN_ASSERT_EQ(numEdges(g), 1u);
removeOutEdges(g, 0);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
e1 = addEdge(g, 0, 1, 1005);
SEQAN_ASSERT_EQ(findEdge(g, 0, 1), e1);
SEQAN_ASSERT_EQ(numEdges(g), 1u);
removeInEdges(g, 0);
SEQAN_ASSERT_EQ(numEdges(g), 0u);
}
//////////////////////////////////////////////////////////////////////////////
// Alignment Graph Iterators
SEQAN_DEFINE_TEST(Test_Refinement_AlignmentGraphIterators)
{
typedef String<Dna> TString;
typedef StringSet<TString, Dependent<> > TStringSet;
typedef Id<TStringSet>::Type TId;
typedef Graph<Alignment<TStringSet, void> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
TStringSet str;
TString str0("acaagtaacataaaaaaaaaaaaaaaacccccccccttttttttaaaaa");
appendValue(str, str0);
TString str1("cccaaagggtttttccccccccccccttttttttttaaaaaaagggggggg");
TId id1 = assignValueById(str, str1);
TString str2("cacatgtaatcatgggggggggccccccttttaaaaaaaaaaatttt");
appendValue(str, str2);
TGraph g(str);
TVertexDescriptor v0 = addVertex(g, id1, 0, 1);
addVertex(g, id1, 1, 1); addVertex(g, id1, 2, 1);
addVertex(g, id1, 3, 1); addVertex(g, id1, 4, 1);
addEdge(g, 2, 0);
addEdge(g, 4, 1);
addEdge(g, 4, 2);
removeVertex(g, 3);
// Vertex Iterator
typedef Iterator<TGraph, VertexIterator>::Type TVertexIterator;
TVertexIterator itV(g);
SEQAN_ASSERT(atBegin(itV));
SEQAN_ASSERT_EQ(getValue(itV), 0u);
SEQAN_ASSERT_EQ(value(itV), 0u);
SEQAN_ASSERT_EQ(*itV, 0u);
goNext(itV);
SEQAN_ASSERT(!atBegin(itV));
SEQAN_ASSERT_EQ(getValue(itV), 1u);
++itV;
SEQAN_ASSERT_EQ(getValue(itV), 2u);
SEQAN_ASSERT(!atEnd(itV));
goPrevious(itV);
SEQAN_ASSERT_EQ(*itV, 1u);
SEQAN_ASSERT_NOT(atEnd(itV));
itV--;
SEQAN_ASSERT_EQ(getValue(itV), 0u);
SEQAN_ASSERT(atBegin(itV));
// OutEdge Iterator
typedef Iterator<TGraph, OutEdgeIterator>::Type TOutEdgeIterator;
TOutEdgeIterator it(g, v0);
SEQAN_ASSERT_EQ(sourceVertex(g, getValue(it)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, getValue(it)), 2u);
SEQAN_ASSERT_EQ(sourceVertex(g, value(it)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, *it), 2u);
SEQAN_ASSERT_NOT(atEnd(it));
SEQAN_ASSERT(atBegin(it));
goNext(it);
SEQAN_ASSERT(atEnd(it));
SEQAN_ASSERT_NOT(atBegin(it));
goPrevious(it);
SEQAN_ASSERT_EQ(sourceVertex(g, getValue(it)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, getValue(it)), 2u);
--it;
it--;
SEQAN_ASSERT(atBegin(it));
TOutEdgeIterator it2(g, v0);
TOutEdgeIterator it3;
it3 = it;
SEQAN_ASSERT(it == it2);
SEQAN_ASSERT(it2 == it3);
goEnd(it);
SEQAN_ASSERT(it2 != it);
goEnd(it2);
SEQAN_ASSERT(it2 == it);
goBegin(it2);
SEQAN_ASSERT(it2 != it);
SEQAN_ASSERT_EQ(&g, &hostGraph(it));
// EdgeIterator
typedef Iterator<TGraph, EdgeIterator>::Type TEdgeIterator;
TEdgeIterator itEdge(g);
SEQAN_ASSERT_EQ(sourceVertex(g, getValue(itEdge)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, getValue(itEdge)), 2u);
SEQAN_ASSERT_EQ(sourceVertex(g, value(itEdge)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, *itEdge), 2u);
SEQAN_ASSERT_NOT(atEnd(itEdge));
SEQAN_ASSERT(atBegin(itEdge));
goNext(itEdge);
SEQAN_ASSERT_EQ(sourceVertex(g, value(itEdge)), 1u);
SEQAN_ASSERT_EQ(targetVertex(g, *itEdge), 4u);
++itEdge;
--itEdge;
SEQAN_ASSERT_EQ(sourceVertex(g, value(itEdge)), 1u);
SEQAN_ASSERT_EQ(targetVertex(g, *itEdge), 4u);
goEnd(itEdge);
SEQAN_ASSERT(atEnd(itEdge));
SEQAN_ASSERT_NOT(atBegin(itEdge));
goBegin(itEdge);
SEQAN_ASSERT_NOT(atEnd(itEdge));
SEQAN_ASSERT(atBegin(itEdge));
// Adjacency Iterator
typedef Iterator<TGraph, AdjacencyIterator>::Type TAdjacencyIterator;
TAdjacencyIterator itAdj(g, 2);
SEQAN_ASSERT_EQ(getValue(itAdj), 4u);
SEQAN_ASSERT_EQ(&hostGraph(itAdj), &g);
SEQAN_ASSERT_EQ(value(itAdj), 4u);
SEQAN_ASSERT_EQ(*itAdj, 4u);
SEQAN_ASSERT_NOT(atEnd(itAdj));
SEQAN_ASSERT(atBegin(itAdj));
goNext(itAdj);
SEQAN_ASSERT_EQ(*itAdj, 0u);
SEQAN_ASSERT_NOT(atEnd(itAdj));
SEQAN_ASSERT_NOT(atBegin(itAdj));
++itAdj;
SEQAN_ASSERT(atEnd(itAdj));
SEQAN_ASSERT_NOT(atBegin(itAdj));
goPrevious(itAdj);
--itAdj;
SEQAN_ASSERT_EQ(*itAdj, 4u);
goBegin(itAdj);
SEQAN_ASSERT(atBegin(itAdj));
goEnd(itAdj);
SEQAN_ASSERT(atEnd(itAdj));
// Bfs Iterator
typedef Iterator<TGraph, BfsIterator>::Type TBfsIterator;
TBfsIterator bfsIt(g, 2);
SEQAN_ASSERT_NOT(atEnd(bfsIt));
SEQAN_ASSERT(atBegin(bfsIt));
++bfsIt;
SEQAN_ASSERT_EQ(getValue(bfsIt), 4u);
SEQAN_ASSERT_EQ(&hostGraph(bfsIt), &g);
SEQAN_ASSERT_EQ(value(bfsIt), 4u);
SEQAN_ASSERT_EQ(*bfsIt, 4u);
goNext(bfsIt);
SEQAN_ASSERT_EQ(value(bfsIt), 0u);
// Dfs Iterator
typedef Iterator<TGraph, DfsPreorder>::Type TDfsPreorder;
TDfsPreorder dfsIt(g, 2);
SEQAN_ASSERT_NOT(atEnd(dfsIt));
SEQAN_ASSERT(atBegin(dfsIt));
SEQAN_ASSERT_EQ(*dfsIt, 2u);
++dfsIt;
SEQAN_ASSERT_EQ(getValue(dfsIt), 0u);
SEQAN_ASSERT_EQ(&hostGraph(dfsIt), &g);
SEQAN_ASSERT_EQ(value(dfsIt), 0u);
SEQAN_ASSERT_EQ(*dfsIt, 0u);
goNext(dfsIt);
}
//////////////////////////////////////////////////////////////////////////////
// Output Alignments in Alignment Graph
SEQAN_DEFINE_TEST(Test_Refinement_AlignmentGraphOutput)
{
// Alignments
typedef String<char> TString;
typedef StringSet<TString, Dependent<> > TStringSet;
typedef Id<TStringSet>::Type TId;
typedef Graph<Alignment<TStringSet, void> > TAlignmentGraph;
typedef VertexDescriptor<TAlignmentGraph>::Type TVD;
//typedef EdgeDescriptor<TAlignmentGraph>::Type TED;
TStringSet str;
TString str0("Garfieldthelastfatcat");
TId i0 = assignValueById(str, str0);
TString str1("Garfieldthefastcat");
TId i1 = assignValueById(str, str1);
TString str2("Garfieldtheveryfastcat");
TId i2 = assignValueById(str, str2);
TString str3("thefatcat");
TId i3 = assignValueById(str, str3);
TAlignmentGraph g(str);
TVD vH = addVertex(g, i1, 8, 3);
SEQAN_ASSERT_EQ(getFirstCoveredPosition(g, i3), 9u); // Not found, length of the sequence
SEQAN_ASSERT_EQ(getLastCoveredPosition(g, i3), 0u); // Not found, 0
SEQAN_ASSERT_EQ(getFirstCoveredPosition(g, i1), 8u);
SEQAN_ASSERT_EQ(getLastCoveredPosition(g, i1), 11u);
TVD vT = addVertex(g, i1, 13, 1); TVD vS = addVertex(g, i3, 6, 3);
TVD vW = addVertex(g, i2, 18, 1); TVD vA = addVertex(g, i0, 0, 8);
SEQAN_ASSERT_EQ(getFirstCoveredPosition(g, i0), 0u);
SEQAN_ASSERT_EQ(getLastCoveredPosition(g, i0), 8u);
TVD vM = addVertex(g, i2, 11, 4); TVD vK = addVertex(g, i2, 0, 8);
TVD vC = addVertex(g, i0, 11, 4); TVD vD = addVertex(g, i0, 15, 2);
TVD vF = addVertex(g, i0, 18, 3); TVD vG = addVertex(g, i1, 0, 8);
addEdge(g, vA, vG);
TVD vI = addVertex(g, i1, 11, 2); TVD vQ = addVertex(g, i3, 3, 2); TVD vB = addVertex(g, i0, 8, 3);
TVD vU = addVertex(g, i1, 14, 1); TVD vE = addVertex(g, i0, 17, 1); TVD vJ = addVertex(g, i1, 15, 3);
TVD vL = addVertex(g, i2, 8, 3);
addEdge(g, vH, vL);
TVD vN = addVertex(g, i2, 15, 2); TVD vV = addVertex(g, i2, 17, 1);
TVD vO = addVertex(g, i2, 19, 3); TVD vP = addVertex(g, i3, 0, 3); TVD vR = addVertex(g, i3, 5, 1);
addEdge(g, vA, vK); addEdge(g, vG, vK); addEdge(g, vB, vH); addEdge(g, vB, vL);
addEdge(g, vB, vP); addEdge(g, vH, vP); addEdge(g, vL, vP); addEdge(g, vC, vM);
addEdge(g, vD, vI); addEdge(g, vD, vQ); addEdge(g, vD, vN); addEdge(g, vI, vQ);
addEdge(g, vI, vN); addEdge(g, vQ, vN); addEdge(g, vT, vV); addEdge(g, vE, vU);
addEdge(g, vE, vW); addEdge(g, vE, vR); addEdge(g, vU, vW); addEdge(g, vU, vR);
addEdge(g, vW, vR); addEdge(g, vF, vJ); addEdge(g, vF, vO); addEdge(g, vF, vS);
addEdge(g, vJ, vO); addEdge(g, vJ, vS); addEdge(g, vO, vS);
SEQAN_ASSERT_EQ(getFirstCoveredPosition(g, i3), 0u);
SEQAN_ASSERT_EQ(getLastCoveredPosition(g, i3), 9u);
// Output of the alignment graph
std::stringstream sstream, expected;
// standard output
sstream << g;
expected << "Alignment matrix:\n"
<< " 0 . : . : \n"
<< " Garfieldthelastfa-tcat\n"
<< " ||||||||||| || ||||\n"
<< " Garfieldthe----fastcat\n"
<< " ||||||||||| |||||||\n"
<< " Garfieldtheveryfastcat\n"
<< " ||| || ||||\n"
<< " --------the----fa-tcat\n\n\n";
SEQAN_ASSERT_EQ(sstream.str(), expected.str());
sstream.str(""); sstream.clear();
expected.str(""); expected.clear();
StringSet<String<char> > seqs;
appendValue(seqs, "seq1");
appendValue(seqs, "seq2");
appendValue(seqs, "seq3");
appendValue(seqs, "seq4");
// fasta output
write(sstream, g, seqs, FastaFormat());
expected << ">seq1\nGarfieldthelastfa-tcat\n"
<< ">seq2\nGarfieldthe----fastcat\n"
<< ">seq3\nGarfieldtheveryfastcat\n"
<< ">seq4\n--------the----fa-tcat\n";
SEQAN_ASSERT_EQ(sstream.str(), expected.str());
sstream.str(""); sstream.clear();
expected.str(""); expected.clear();
// msf output
write(sstream, g, seqs, MsfFormat());
expected << "PileUp\n\n"
<< " MSF: 22 Type: P Check: 0 ..\n\n"
<< " Name: seq1 oo Len: 22 Check: 0 Weight: 1.00\n"
<< " Name: seq2 oo Len: 22 Check: 0 Weight: 1.00\n"
<< " Name: seq3 oo Len: 22 Check: 0 Weight: 1.00\n"
<< " Name: seq4 oo Len: 22 Check: 0 Weight: 1.00\n\n"
<< "//\n\n\n"
<< "seq1 Garfieldth elastfa.tc at\n"
<< "seq2 Garfieldth e....fastc at\n"
<< "seq3 Garfieldth everyfastc at\n"
<< "seq4 ........th e....fa.tc at\n\n\n";
SEQAN_ASSERT_EQ(sstream.str(), expected.str());
sstream.str(""); sstream.clear();
expected.str(""); expected.clear();
// cg viz output
write(sstream, g, seqs, CgVizFormat());
expected << "{DATA Data\n"
<< "\t[__GLOBAL__] tracks=4\n"
<< "\tfasta_id=\"seq1\" sequence=\"Garfieldthelastfatcat\" track=0 type=\"DNA\": 0 20\n"
<< "\tfasta_id=\"seq2\" sequence=\"Garfieldthefastcat\" track=1 type=\"DNA\": 0 17\n"
<< "\tfasta_id=\"seq3\" sequence=\"Garfieldtheveryfastcat\" track=2 type=\"DNA\": 0 21\n"
<< "\tfasta_id=\"seq4\" sequence=\"thefatcat\" track=3 type=\"DNA\": 0 8\n"
<< "}\n"
<< "{DATA 0-seqlen\n"
<< "\t[__GLOBAL__]\n"
<< "\tlength=21:\t0 20\n"
<< "}\n"
<< "{DATA 1-seqlen\n"
<< "\t[__GLOBAL__]\n"
<< "\tlength=18:\t0 17\n"
<< "}\n"
<< "{DATA 2-seqlen\n"
<< "\t[__GLOBAL__]\n"
<< "\tlength=22:\t0 21\n"
<< "}\n"
<< "{DATA 3-seqlen\n"
<< "\t[__GLOBAL__]\n"
<< "\tlength=9:\t0 8\n"
<< "}\n"
<< "{DATA 0-vs-1\n"
<< "\t[__GLOBAL__]\n"
<< "\tsource=0 target=13 edgeId=4 cargo=0 label=the labelOpp=the:\t8 8 11 11\n"
<< "\tsource=4 target=10 edgeId=0 cargo=0 label=Garfield labelOpp=Garfield:\t0 0 8 8\n"
<< "\tsource=8 target=11 edgeId=10 cargo=0 label=fa labelOpp=fa:\t15 11 17 13\n"
<< "\tsource=9 target=16 edgeId=23 cargo=0 label=cat labelOpp=cat:\t18 15 21 18\n"
<< "\tsource=14 target=15 edgeId=17 cargo=0 label=t labelOpp=t:\t14 17 15 18\n"
<< "}\n"
<< "{DATA 0-vs-2\n"
<< "\t[__GLOBAL__]\n"
<< "\tsource=3 target=15 edgeId=18 cargo=0 label=t labelOpp=t:\t18 17 19 18\n"
<< "\tsource=4 target=6 edgeId=2 cargo=0 label=Garfield labelOpp=Garfield:\t0 0 8 8\n"
<< "\tsource=5 target=7 edgeId=9 cargo=0 label=very labelOpp=last:\t11 11 15 15\n"
<< "\tsource=8 target=18 edgeId=12 cargo=0 label=fa labelOpp=fa:\t15 15 17 17\n"
<< "\tsource=9 target=20 edgeId=24 cargo=0 label=cat labelOpp=cat:\t18 19 21 22\n"
<< "\tsource=13 target=17 edgeId=5 cargo=0 label=the labelOpp=the:\t8 8 11 11\n"
<< "}\n"
<< "{DATA 0-vs-3\n"
<< "\t[__GLOBAL__]\n"
<< "\tsource=2 target=9 edgeId=25 cargo=0 label=cat labelOpp=cat:\t6 18 9 21\n"
<< "\tsource=8 target=12 edgeId=11 cargo=0 label=fa labelOpp=fa:\t15 3 17 5\n"
<< "\tsource=13 target=21 edgeId=6 cargo=0 label=the labelOpp=the:\t8 0 11 3\n"
<< "\tsource=15 target=22 edgeId=19 cargo=0 label=t labelOpp=t:\t17 5 18 6\n"
<< "}\n"
<< "{DATA 1-vs-2\n"
<< "\t[__GLOBAL__]\n"
<< "\tsource=0 target=17 edgeId=1 cargo=0 label=the labelOpp=the:\t8 8 11 11\n"
<< "\tsource=1 target=19 edgeId=16 cargo=0 label=s labelOpp=s:\t13 17 14 18\n"
<< "\tsource=3 target=14 edgeId=20 cargo=0 label=t labelOpp=t:\t18 14 19 15\n"
<< "\tsource=6 target=10 edgeId=3 cargo=0 label=Garfield labelOpp=Garfield:\t0 0 8 8\n"
<< "\tsource=11 target=18 edgeId=14 cargo=0 label=fa labelOpp=fa:\t11 15 13 17\n"
<< "\tsource=16 target=20 edgeId=26 cargo=0 label=cat labelOpp=cat:\t15 19 18 22\n"
<< "}\n"
<< "{DATA 1-vs-3\n"
<< "\t[__GLOBAL__]\n"
<< "\tsource=0 target=21 edgeId=7 cargo=0 label=the labelOpp=the:\t8 0 11 3\n"
<< "\tsource=2 target=16 edgeId=27 cargo=0 label=cat labelOpp=cat:\t6 15 9 18\n"
<< "\tsource=11 target=12 edgeId=13 cargo=0 label=fa labelOpp=fa:\t11 3 13 5\n"
<< "\tsource=14 target=22 edgeId=21 cargo=0 label=t labelOpp=t:\t14 5 15 6\n"
<< "}\n"
<< "{DATA 2-vs-3\n"
<< "\t[__GLOBAL__]\n"
<< "\tsource=2 target=20 edgeId=28 cargo=0 label=cat labelOpp=cat:\t6 19 9 22\n"
<< "\tsource=3 target=22 edgeId=22 cargo=0 label=t labelOpp=t:\t18 5 19 6\n"
<< "\tsource=12 target=18 edgeId=15 cargo=0 label=fa labelOpp=fa:\t3 15 5 17\n"
<< "\tsource=17 target=21 edgeId=8 cargo=0 label=the labelOpp=the:\t8 0 11 3\n"
<< "}\n";
SEQAN_ASSERT_EQ(sstream.str(), expected.str());
// GraphViz DOT output.
sstream.str("");
expected.str("");
writeRecords(sstream, g, DotDrawing());
expected << "graph G {\n"
<< "\n"
<< "/* Graph Attributes */\n"
<< "graph [rankdir = LR];\n"
<< "\n"
<< "/* Node Attributes */\n"
<< "node [shape = rectangle, fillcolor = white, style = filled, fontname = \"Times-Italic\"];\n"
<< "\n"
<< "/* Edge Attributes */\n"
<< "edge [fontname = \"Times-Italic\", arrowsize = 0.75, fontsize = 16];\n"
<< "\n"
<< "/* Nodes */\n"
<< "0 [label = \"[8,11)\", group = 1];\n"
<< "1 [label = \"[13,14)\", group = 1];\n"
<< "2 [label = \"[6,9)\", group = 3];\n"
<< "3 [label = \"[18,19)\", group = 2];\n"
<< "4 [label = \"[0,8)\", group = 0];\n"
<< "5 [label = \"[11,15)\", group = 2];\n"
<< "6 [label = \"[0,8)\", group = 2];\n"
<< "7 [label = \"[11,15)\", group = 0];\n"
<< "8 [label = \"[15,17)\", group = 0];\n"
<< "9 [label = \"[18,21)\", group = 0];\n"
<< "10 [label = \"[0,8)\", group = 1];\n"
<< "11 [label = \"[11,13)\", group = 1];\n"
<< "12 [label = \"[3,5)\", group = 3];\n"
<< "13 [label = \"[8,11)\", group = 0];\n"
<< "14 [label = \"[14,15)\", group = 1];\n"
<< "15 [label = \"[17,18)\", group = 0];\n"
<< "16 [label = \"[15,18)\", group = 1];\n"
<< "17 [label = \"[8,11)\", group = 2];\n"
<< "18 [label = \"[15,17)\", group = 2];\n"
<< "19 [label = \"[17,18)\", group = 2];\n"
<< "20 [label = \"[19,22)\", group = 2];\n"
<< "21 [label = \"[0,3)\", group = 3];\n"
<< "22 [label = \"[5,6)\", group = 3];\n"
<< "\n"
<< "/* Edges */\n"
<< "0 -- 21 [];\n"
<< "0 -- 13 [];\n"
<< "0 -- 17 [];\n"
<< "1 -- 19 [];\n"
<< "2 -- 20 [];\n"
<< "2 -- 16 [];\n"
<< "2 -- 9 [];\n"
<< "3 -- 22 [];\n"
<< "3 -- 14 [];\n"
<< "3 -- 15 [];\n"
<< "4 -- 6 [];\n"
<< "4 -- 10 [];\n"
<< "5 -- 7 [];\n"
<< "6 -- 10 [];\n"
<< "8 -- 18 [];\n"
<< "8 -- 12 [];\n"
<< "8 -- 11 [];\n"
<< "9 -- 20 [];\n"
<< "9 -- 16 [];\n"
<< "11 -- 18 [];\n"
<< "11 -- 12 [];\n"
<< "12 -- 18 [];\n"
<< "13 -- 21 [];\n"
<< "13 -- 17 [];\n"
<< "14 -- 22 [];\n"
<< "14 -- 15 [];\n"
<< "15 -- 22 [];\n"
<< "16 -- 20 [];\n"
<< "17 -- 21 [];\n"
<< "\n"
<< "4 -- 13 [len=3.0, arrowhead=vee];\n"
<< "13 -- 7 [len=3.0, arrowhead=vee];\n"
<< "7 -- 8 [len=3.0, arrowhead=vee];\n"
<< "8 -- 15 [len=3.0, arrowhead=vee];\n"
<< "15 -- 9 [len=3.0, arrowhead=vee];\n"
<< "10 -- 0 [len=3.0, arrowhead=vee];\n"
<< "0 -- 11 [len=3.0, arrowhead=vee];\n"
<< "11 -- 1 [len=3.0, arrowhead=vee];\n"
<< "1 -- 14 [len=3.0, arrowhead=vee];\n"
<< "14 -- 16 [len=3.0, arrowhead=vee];\n"
<< "6 -- 17 [len=3.0, arrowhead=vee];\n"
<< "17 -- 5 [len=3.0, arrowhead=vee];\n"
<< "5 -- 18 [len=3.0, arrowhead=vee];\n"
<< "18 -- 19 [len=3.0, arrowhead=vee];\n"
<< "19 -- 3 [len=3.0, arrowhead=vee];\n"
<< "3 -- 20 [len=3.0, arrowhead=vee];\n"
<< "21 -- 12 [len=3.0, arrowhead=vee];\n"
<< "12 -- 22 [len=3.0, arrowhead=vee];\n"
<< "22 -- 2 [len=3.0, arrowhead=vee];\n"
<< "\n"
<< "}\n";
SEQAN_ASSERT_EQ(sstream.str(), expected.str());
}
//////////////////////////////////////////////////////////////////////////////
SEQAN_DEFINE_TEST(Test_Refinement_HeaviestCommonSubsequence)
{
typedef String<AminoAcid> TString;
typedef StringSet<TString, Dependent<> > TStringSet;
typedef Graph<Alignment<TStringSet, int> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
TString s1 = "aaa";
TString s2 = "aa";
TStringSet strSet;
assignValueById(strSet, s1);
assignValueById(strSet, s2);
TGraph g(strSet);
TVertexDescriptor v0 = addVertex(g, 0, 0, 1);
TVertexDescriptor v1 = addVertex(g, 0, 1, 1);
TVertexDescriptor v2 = addVertex(g, 0, 2, 1);
TVertexDescriptor v3 = addVertex(g, 1, 0, 1);
TVertexDescriptor v4 = addVertex(g, 1, 1, 1);
addEdge(g, 0, 3, 10); addEdge(g, 0, 4, 15);
addEdge(g, 1, 3, 10); addEdge(g, 1, 4, 10);
addEdge(g, 2, 3, 15); addEdge(g, 2, 4, 10);
String<String<TVertexDescriptor> > str1;
String<String<TVertexDescriptor> > str2;
String<String<TVertexDescriptor> > align;
String<TVertexDescriptor> tmp;
clear(tmp); appendValue(tmp, v0); appendValue(str1, tmp);
clear(tmp); appendValue(tmp, v1); appendValue(str1, tmp);
clear(tmp); appendValue(tmp, v2); appendValue(str1, tmp);
clear(tmp); appendValue(tmp, v3); appendValue(str2, tmp);
clear(tmp); appendValue(tmp, v4); appendValue(str2, tmp);
SEQAN_ASSERT_EQ(heaviestCommonSubsequence(g, str1, str2, align), 20);
// TODO(bkehr): Add more assertions.
s1 = "aaaaa";
s2 = "aaa";
clear(strSet);
assignValueById(strSet, s1);
assignValueById(strSet, s2);
assignStringSet(g, strSet);
v0 = addVertex(g, 0, 0, 2);
v1 = addVertex(g, 0, 2, 1);
v2 = addVertex(g, 0, 3, 2);
v3 = addVertex(g, 1, 0, 1);
v4 = addVertex(g, 1, 1, 2);
addEdge(g, 0, 4, 10); addEdge(g, 1, 3, 20);
clear(align);
clear(str1);
clear(str2);
clear(tmp); appendValue(tmp, v0); appendValue(str1, tmp);
clear(tmp); appendValue(tmp, v1); appendValue(str1, tmp);
clear(tmp); appendValue(tmp, v2); appendValue(str1, tmp);
clear(tmp); appendValue(tmp, v3); appendValue(str2, tmp);
clear(tmp); appendValue(tmp, v4); appendValue(str2, tmp);
heaviestCommonSubsequence(g, str1, str2, align);
// TODO(bkehr): Add assertions.
}
//////////////////////////////////////////////////////////////////////////////
// Graph AlignmentOutEdgeIterator
SEQAN_DEFINE_TEST(Test_Refinement_OutEdgeIteratorAlignment)
{
typedef String<Dna> TString;
typedef StringSet<TString, Dependent<> > TStringSet;
typedef Graph<Alignment<TStringSet> > TGraph;
typedef VertexDescriptor<TGraph>::Type TVertexDescriptor;
//typedef EdgeDescriptor<TGraph>::Type TEdgeDescriptor;
TString str1 = "aa";
TString str2 = "ac";
TStringSet strSet;
appendValue(strSet, str1);
appendValue(strSet, str2);
TGraph g(strSet);
TVertexDescriptor v0 = addVertex(g,0,0,1);
addVertex(g,0,1,1);
addVertex(g,1,0,1);
addEdge(g,0,2,10);
addVertex(g,1,1,1);
typedef Iterator<TGraph, OutEdgeIterator>::Type TOutEdgeIterator;
TOutEdgeIterator it(g, v0);
// Slow
SEQAN_ASSERT_EQ(sourceVertex(g, getValue(it)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, getValue(it)), 2u);
SEQAN_ASSERT_EQ(sourceVertex(g, value(it)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, *it), 2u);
SEQAN_ASSERT_NOT(atEnd(it));
SEQAN_ASSERT(atBegin(it));
// Fast
SEQAN_ASSERT_EQ(sourceVertex(it), 0u);
SEQAN_ASSERT_EQ(targetVertex(it), 2u);
SEQAN_ASSERT_NOT(atEnd(it));
SEQAN_ASSERT(atBegin(it));
++it;
SEQAN_ASSERT(atEnd(it));
SEQAN_ASSERT_NOT(atBegin(it));
goPrevious(it);
SEQAN_ASSERT_EQ(sourceVertex(g, getValue(it)), 0u);
SEQAN_ASSERT_EQ(targetVertex(g, getValue(it)), 2u);
goNext(it);
--it;
TOutEdgeIterator it2(g, v0);
TOutEdgeIterator it3;
it3 = it;
SEQAN_ASSERT(it == it2);
SEQAN_ASSERT(it2 == it3);
goEnd(it);
SEQAN_ASSERT(it2 != it);
goEnd(it2);
SEQAN_ASSERT(it2 == it);
goBegin(it2);
SEQAN_ASSERT(it2 != it);
SEQAN_ASSERT_EQ(&g, &hostGraph(it));
}
} // namespace seqan2
#endif
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