File: PAM250

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#
# This matrix was produced by "pam" Version 1.0.6 [28-Jul-93]
#
# PAM 250 substitution matrix, scale = ln(2)/3 = 0.231049
#
# Expected score = -0.844, Entropy = 0.354 bits
#
# Lowest score = -8, Highest score = 17
#
#
#  added J-Column as (I+L)/2 and U == X
#  reordered to be (alphabetically sorted; X *)
   A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  Y  Z  X  *
A  2  0 -2  0  0 -3  1 -1 -1 -2 -1 -2 -1  0  0  1  0 -2  1  1  0  0 -6 -3  0  0 -8
B  0  3 -4  3  3 -4  0  1 -2 -3  1 -3 -2  2 -1 -1  1 -1  0  0 -1 -2 -5 -3  2 -1 -8
C -2 -4 12 -5 -5 -4 -3 -3 -2 -4 -5 -6 -5 -4 -3 -3 -5 -4  0 -2 -3 -2 -8  0 -5 -3 -8
D  0  3 -5  4  3 -6  1  1 -2 -3  0 -4 -3  2 -1 -1  2 -1  0  0 -1 -2 -7 -4  3 -1 -8
E  0  3 -5  3  4 -5  0  1 -2 -3  0 -3 -2  1 -1 -1  2 -1  0  0 -1 -2 -7 -4  3 -1 -8
F -3 -4 -4 -6 -5  9 -5 -2  1  2 -5  2  0 -3 -2 -5 -5 -4 -3 -3 -2 -1  0  7 -5 -2 -8
G  1  0 -3  1  0 -5  5 -2 -3 -4 -2 -4 -3  0 -1  0 -1 -3  1  0 -1 -1 -7 -5  0 -1 -8
H -1  1 -3  1  1 -2 -2  6 -2 -2  0 -2 -2  2 -1  0  3  2 -1 -1 -1 -2 -3  0  2 -1 -8
I -1 -2 -2 -2 -2  1 -3 -2  5  4 -2  2  2 -2 -1 -2 -2 -2 -1  0 -1  4 -5 -1 -2 -1 -8
J -2 -3 -4 -3 -3  2 -4 -2  4  4 -3  4  3 -3 -1 -3 -2 -3 -2 -1 -1  3 -4 -1 -3 -1 -8
K -1  1 -5  0  0 -5 -2  0 -2 -3  5 -3  0  1 -1 -1  1  3  0  0 -1 -2 -3 -4  0 -1 -8
L -2 -3 -6 -4 -3  2 -4 -2  2  4 -3  6  4 -3 -1 -3 -2 -3 -3 -2 -1  2 -2 -1 -3 -1 -8
M -1 -2 -5 -3 -2  0 -3 -2  2  3  0  4  6 -2 -1 -2 -1  0 -2 -1 -1  2 -4 -2 -2 -1 -8
N  0  2 -4  2  1 -3  0  2 -2 -3  1 -3 -2  2  0  0  1  0  1  0  0 -2 -4 -2  1  0 -8
O  0 -1 -3 -1 -1 -2 -1 -1 -1 -1 -1 -1 -1  0 -1 -1 -1 -1  0  0 -1 -1 -4 -2 -1 -1 -8
P  1 -1 -3 -1 -1 -5  0  0 -2 -3 -1 -3 -2  0 -1  6  0  0  1  0 -1 -1 -6 -5  0 -1 -8
Q  0  1 -5  2  2 -5 -1  3 -2 -2  1 -2 -1  1 -1  0  4  1 -1 -1 -1 -2 -5 -4  3 -1 -8
R -2 -1 -4 -1 -1 -4 -3  2 -2 -3  3 -3  0  0 -1  0  1  6  0 -1 -1 -2  2 -4  0 -1 -8
S  1  0  0  0  0 -3  1 -1 -1 -2  0 -3 -2  1  0  1 -1  0  2  1  0 -1 -2 -3  0  0 -8
T  1  0 -2  0  0 -3  0 -1  0 -1  0 -2 -1  0  0  0 -1 -1  1  3  0  0 -5 -3 -1  0 -8
U  0 -1 -3 -1 -1 -2 -1 -1 -1 -1 -1 -1 -1  0 -1 -1 -1 -1  0  0 -1 -1 -4 -2 -1 -1 -8
V  0 -2 -2 -2 -2 -1 -1 -2  4  3 -2  2  2 -2 -1 -1 -2 -2 -1  0 -1  4 -6 -2 -2 -1 -8
W -6 -5 -8 -7 -7  0 -7 -3 -5 -4 -3 -2 -4 -4 -4 -6 -5  2 -2 -5 -4 -6 17  0 -6 -4 -8
Y -3 -3  0 -4 -4  7 -5  0 -1 -1 -4 -1 -2 -2 -2 -5 -4 -4 -3 -3 -2 -2  0 10 -4 -2 -8
Z  0  2 -5  3  3 -5  0  2 -2 -3  0 -3 -2  1 -1  0  3  0  0 -1 -1 -2 -6 -4  3 -1 -8
X  0 -1 -3 -1 -1 -2 -1 -1 -1 -1 -1 -1 -1  0 -1 -1 -1 -1  0  0 -1 -1 -4 -2 -1 -1 -8
* -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8 -8  1