File: bigpicturegrid.cpp

package info (click to toggle)
seqtools 4.44.1%2Bdfsg-7
  • links: PTS, VCS
  • area: main
  • in suites: bookworm
  • size: 28,492 kB
  • sloc: cpp: 53,636; sh: 12,232; makefile: 386
file content (878 lines) | stat: -rw-r--r-- 32,107 bytes parent folder | download | duplicates (4)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
/*  File: bigpicturegrid.c
 *  Author: Gemma Barson, 2009-11-23
 *  Copyright (c) 2009 - 2012 Genome Research Ltd
 * ---------------------------------------------------------------------------
 * SeqTools is free software; you can redistribute it and/or
 * modify it under the terms of the GNU General Public License
 * as published by the Free Software Foundation; either version 3
 * of the License, or (at your option) any later version.
 * 
 * This program is distributed in the hope that it will be useful,
 * but WITHOUT ANY WARRANTY; without even the implied warranty of
 * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
 * GNU General Public License for more details.
 * 
 * You should have received a copy of the GNU General Public License
 * along with this program; if not, write to the Free Software
 * Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA  02111-1307, USA.
 * or see the on-line version at http://www.gnu.org/copyleft/gpl.txt
 * ---------------------------------------------------------------------------
 * This file is part of the SeqTools sequence analysis package, 
 * written by
 *      Gemma Barson      (Sanger Institute, UK)  <gb10@sanger.ac.uk>
 * 
 * based on original code by
 *      Erik Sonnhammer   (SBC, Sweden)           <Erik.Sonnhammer@sbc.su.se>
 * 
 * and utilizing code taken from the AceDB and ZMap packages, written by
 *      Richard Durbin    (Sanger Institute, UK)  <rd@sanger.ac.uk>
 *      Jean Thierry-Mieg (CRBM du CNRS, France)  <mieg@kaa.crbm.cnrs-mop.fr>
 *      Ed Griffiths      (Sanger Institute, UK)  <edgrif@sanger.ac.uk>
 *      Roy Storey        (Sanger Institute, UK)  <rds@sanger.ac.uk>
 *      Malcolm Hinsley   (Sanger Institute, UK)  <mh17@sanger.ac.uk>
 *
 * Description: See bigpicturegrid.h
 *----------------------------------------------------------------------------
 */

#include <blixemApp/bigpicturegrid.hpp>
#include <blixemApp/blxcontext.hpp>
#include <blixemApp/bigpicture.hpp>
#include <blixemApp/detailview.hpp>
#include <blixemApp/detailviewtree.hpp>
#include <blixemApp/blxwindow.hpp>
#include <blixemApp/blxpanel.hpp>
#include <seqtoolsUtils/utilities.hpp>
#include <math.h>
#include <string.h>
#include <stdlib.h>
#include <algorithm>

using namespace std;


#define BIG_PICTURE_MSP_LINE_NAME	"BigPictureMspLine"
#define DEFAULT_MSP_LINE_HEIGHT		3	  /* the height of the MSP lines in the grid */
#define DEFAULT_GRID_Y_PADDING		5	  /* this provides space between the grid and the edge of the widget */
#define MIN_MSP_LINE_WIDTH		1	  /* used to make sure that MSP lines never shrink to nothing */

typedef struct _DrawGridData
{
  GtkWidget *grid;
  GdkDrawable *drawable;
  GdkGC *gc;
  GdkColor *color;
  GdkColor *shadowColor;
  gboolean drawColinearityLines;
} DrawGridData;

  

/* Local function declarations */
static BlxContext*	    gridGetContext(GtkWidget *grid);
static IntRange*	    gridGetDisplayRange(GtkWidget *grid);
static GdkColor*	    gridGetMspLineColor(GtkWidget *grid, const gboolean selected);
static GtkWidget*	    gridGetBlxWindow(GtkWidget *grid);
static void                 drawBigPictureGrid(GtkWidget *grid, GdkDrawable *drawable);

/***********************************************************
 *                     Utility functions	           *
 ***********************************************************/

/* Calls the given function (passed as the data pointer) on the given widget 
 * if it is a grid in the big picture view, or, if it is a container, 
 * calls the function on all children/grandchildren/etc that are grids */
void callFuncOnAllBigPictureGrids(GtkWidget *widget, gpointer data)
{
  const gchar *name = gtk_widget_get_name(widget);
  if (strcmp(name, BIG_PICTURE_GRID_NAME) == 0)
    {
      GtkCallback func = (GtkCallback)data;
      func(widget, NULL);
    }
  else if (GTK_IS_CONTAINER(widget))
    {
      gtk_container_foreach(GTK_CONTAINER(widget), callFuncOnAllBigPictureGrids, data);
    }
}


static int gridGetNumVCells(GtkWidget *grid)
{
  GtkWidget *bigPicture = gridGetBigPicture(grid);
  return bigPictureGetNumVCells(bigPicture);
}


/* Convert an ID% value to the y coord on the given grid */
gint convertValueToGridPos(GtkWidget *grid, const gdouble value)
{
  /* The top line of the grid is drawn one cell height down from the top of the grid border */
  GridProperties *properties = gridGetProperties(grid);
  
  DoubleRange *valRange = bigPictureGetPercentIdRange(properties->bigPicture);
  gdouble percent = (valRange->max - value) / (valRange->max - valRange->min);
  
  /* Make sure we do the multiplication on doubles before rounding to int */
  gint result = properties->gridRect.y + roundNearest((gdouble)properties->gridRect.height * percent);
  return result;
}


/* Calculates the size and position of an MSP line in the given grid. Return
 * args can be null if not required. */
static void calculateMspLineDimensions(GtkWidget *grid, 
                                       const MSP* const msp, 
                                       gboolean clip,
                                       int *x, 
                                       int *y, 
                                       int *width, 
                                       int *height)
{
  BlxContext *bc = gridGetContext(grid);
  GridProperties *gridProperties = gridGetProperties(grid);

  /* Get the display range in dna coords */
  IntRange dnaDispRange;
  convertDisplayRangeToDnaRange(gridGetDisplayRange(grid), bc->seqType, bc->numFrames, bc->displayRev, &bc->refSeqRange, &dnaDispRange);

  /* The grid pos for coords gives the left edge of the coord, so draw to max + 1 to be inclusive */
  const int mspMin = msp->qRange.min(true, bc->displayRev);
  const int mspMax = msp->qRange.max(true, bc->displayRev);
  
  const int x1 = convertBaseIdxToRectPos(mspMin, &gridProperties->gridRect, &dnaDispRange, TRUE, bc->displayRev, TRUE);
  const int x2 = convertBaseIdxToRectPos(mspMax, &gridProperties->gridRect, &dnaDispRange, TRUE, bc->displayRev, TRUE);
  
  const int xMin = min(x1, x2);
  const int xMax = max(x1, x2);
  
  if (x)
    *x = xMin;
    
  if (width)
    *width = max((xMax - xMin), MIN_MSP_LINE_WIDTH);
  
  /* Find where in the y axis we should draw the line, based on the %ID value */
  if (y)
    *y = convertValueToGridPos(grid, msp->id);
    
  if (height)
    *height = gridProperties->mspLineHeight;
}


/* Returns true if the given msp is displayed in the given grid, i.e. is the correct
 * strand, is not an intron or exon, and (if checkRange is true) is not out of range */
static gboolean mspShownInGrid(const MSP* const msp, GtkWidget *grid, gboolean checkRange)
{
  gboolean result = FALSE ; 

  list<const SequenceGroup*> groups ;
  BlxContext *bc = NULL ;

  /* First check strand and type */
  result = (grid && msp && mspIsBlastMatch(msp) && mspGetRefStrand(msp) == gridGetStrand(grid)) ;

  /* If in a group, check that the group is visible */
  if (result)
    {
      bc = gridGetContext(grid) ;
      groups = bc->getSequenceGroups(msp->sSequence) ;
      result = bc->isGroupVisible(groups, msp->sSequence->type) ;
    }
  
  if (result)
    {
      if (checkRange)
        {
          /* See if the msp lies within the grid's display range */
          const IntRange* const displayRange = gridGetDisplayRange(grid);
          const IntRange* const mspRange = mspGetDisplayRange(msp);
          result = rangesOverlap(mspRange, displayRange);
        }
      else
        {
          /* We're just checking the correct type and strand, so return true */
          result = TRUE;
        }
    }
  
  return result;
}


/* Draw a line on the given grid to represent the given match */
static void drawMspLine(const MSP* const msp, DrawGridData *drawData)
{
  /* Ignore introns. */
  if (mspShownInGrid(msp, drawData->grid, TRUE))
    {
      gdk_gc_set_subwindow(drawData->gc, GDK_INCLUDE_INFERIORS);
      gdk_gc_set_foreground(drawData->gc, drawData->color);
      
      /* Calculate where it should go */
      int x, y, width, height;
      calculateMspLineDimensions(drawData->grid, msp, TRUE, &x, &y, &width, &height);
      
      /* Draw a block rectangle */
      gdk_draw_rectangle(drawData->drawable, drawData->gc, TRUE, x, y, width, height);
      
      /* Draw a drop-shadow, to make sure it is always visible even in the paler highlight colors */
      const int shadowHt = 1;
      gdk_gc_set_foreground(drawData->gc, drawData->shadowColor);
      gdk_gc_set_line_attributes(drawData->gc, shadowHt, GDK_LINE_SOLID, GDK_CAP_BUTT, GDK_JOIN_MITER);
      
      int yBottom = y + height - shadowHt;
      gdk_draw_line(drawData->drawable, drawData->gc, x, yBottom, x + width, yBottom);
      
      /* only draw the right-hand-side if the width is great enough to fit it and still be visible */
      if (width > shadowHt + 1)
      {
	int xRight = x + width - shadowHt;
	gdk_draw_line(drawData->drawable, drawData->gc, xRight, y, xRight, y + height);
      }
    }
}


/* Draw colinearity lines between the given MSP list item and the next one (if there is one) */
static void drawColinearityLines(GList *mspListItem, DrawGridData *drawData)
{
  g_return_if_fail(drawData);

  BlxContext *bc = gridGetContext(drawData->grid);
  
  if (drawData->drawColinearityLines && mspListItem && mspListItem->next && bc->flags[BLXFLAG_SHOW_COLINEARITY])
    {
      const IntRange* const displayRange = gridGetDisplayRange(drawData->grid);

      const MSP* msp1 = (const MSP*)mspListItem->data;
      const MSP* msp2 = (const MSP*)mspListItem->next->data;

      /* If the display is reversed we need to swap the order of the msps */
      if (bc->displayRev)
        {
          msp1 = (const MSP*)mspListItem->next->data;
          msp2 = (const MSP*)mspListItem->data;
        }

      /* Check that the line will lie within the visible range */
      if ((msp1->displayRange.max() < displayRange->max() && msp2->displayRange.min() > displayRange->min()) ||
          (msp1->displayRange.max() > displayRange->max() && msp2->displayRange.min() < displayRange->min()))
        {
          ColinearityType colinearityType = COLINEAR_INVALID;

          if ((bc->displayRev && msp1->qStrand == BLXSTRAND_FORWARD) || (!bc->displayRev && msp1->qStrand != BLXSTRAND_FORWARD))
            colinearityType = mspIsColinear(msp2, msp1);
          else
            colinearityType = mspIsColinear(msp1, msp2);

          if (colinearityType != COLINEAR_INVALID)
            {
              /* get the line color */
              GdkColor *color = NULL;

              if (colinearityType == COLINEAR_PERFECT)
                color = getGdkColor(BLXCOLOR_COLINEAR_PERFECT, bc->defaultColors, FALSE, bc->usePrintColors);
              else if (colinearityType == COLINEAR_IMPERFECT)
                color = getGdkColor(BLXCOLOR_COLINEAR_IMPERFECT, bc->defaultColors, FALSE, bc->usePrintColors);
              else
                color = getGdkColor(BLXCOLOR_COLINEAR_NOT, bc->defaultColors, FALSE, bc->usePrintColors);

              gdk_gc_set_foreground(drawData->gc, color);

              /* get coords of the msp lines */
              int x1, y1, width1, height1;
              int x2, y2, width2, height2;
              calculateMspLineDimensions(drawData->grid, msp1, FALSE, &x1, &y1, &width1, &height1);
              calculateMspLineDimensions(drawData->grid, msp2, FALSE, &x2, &y2, &width2, &height2);

              /* get coords of line to draw */
              IntRange lineXRange(x1 + width1, x2);
              IntRange lineYRange(y1 + height1 / 2, y2 + height2 / 2);

              gdk_draw_line(drawData->drawable, drawData->gc, 
                            lineXRange.min(), lineYRange.min(), lineXRange.max(), lineYRange.max());
            }
        }
    }
}


/* Draw the MSPs for the given sequence in the given color. */
static void drawSequenceMspLines(gpointer listItemData, gpointer data)
{
  const BlxSequence *seq = (const BlxSequence*)listItemData;
  
  /* Only applicable to alignments and transcripts */
  if (!blxSequenceShownInGrid(seq))
    return;
  
  DrawGridData *drawData = (DrawGridData*)data;  
  GList *mspListItem = seq->mspList;

  for ( ; mspListItem; mspListItem = mspListItem->next)
    {
      MSP *msp = (MSP*)(mspListItem->data);

      /* Draw the msp (if it's on this grid and is in the visible range) */
      if (mspShownInGrid(msp, drawData->grid, TRUE))
        drawMspLine(msp, drawData);

      /* Draw colinearity lines between this and the next msp. Note that we need to call this
       * even if this msp is out of range, in case the next msp is in range. */
      if (mspShownInGrid(msp, drawData->grid, FALSE))
        drawColinearityLines(mspListItem, drawData);
    }
}


/* Draw MSP lines that are in groups. Use the highlight color of the group if one is set */
static void drawGroupedMspLines(gpointer listItemData, gpointer data)
{
  SequenceGroup *seqGroup = (SequenceGroup*)listItemData;
  DrawGridData *drawData = (DrawGridData*)data;
  GdkColor *origColor = drawData->color;
  GdkColor *origShadowColor = drawData->shadowColor;

  /* Use the group's highlight color, if this sequence should be highlighted */
  if (seqGroup->highlighted)
    {
      /* Use the group's highlight color */
      drawData->color = &seqGroup->highlightColor;
      GdkColor shadowColor;
      getDropShadowColor(drawData->color, &shadowColor);
      drawData->shadowColor = &shadowColor;
      
      g_list_foreach(seqGroup->seqList, drawSequenceMspLines, drawData);

      /* Set the draw data back to its original values */
      drawData->color = origColor;
      drawData->shadowColor = origShadowColor;
    }
  else
    {
      g_list_foreach(seqGroup->seqList, drawSequenceMspLines, drawData);
    }
  
}


/* Draw a line for each MSP in the given grid */
static void drawMspLines(GtkWidget *grid, GdkDrawable *drawable)
{
  BlxContext *bc = gridGetContext(grid);
  GdkGC *gc = gdk_gc_new(drawable);
  
  DrawGridData drawData = {
    grid, 
    drawable, 
    gc, 
    gridGetMspLineColor(grid, FALSE), 
    gridGetMspLineColor(grid, FALSE),
    FALSE
  };
  
  /* Draw all MSPs for this grid */ 
  g_list_foreach(bc->matchSeqs, drawSequenceMspLines, &drawData);  

  /* Now draw MSPs that are in groups (to do: it would be good to do this in reverse
   * Sort Order, so that those ordered first get drawn last and therefore appear on top) */
  g_list_foreach(bc->sequenceGroups, drawGroupedMspLines, &drawData);
  
  /* Finally, draw selected sequences. These will appear on top of everything else and will have
   * colinearity lines displayed (we only ever display colinearity lines for selected sequences
   * in the grid because it would be too cluttered otherwise). */
  drawData.color = gridGetMspLineColor(grid, TRUE);
  GdkColor shadowColor;
  getDropShadowColor(drawData.color, &shadowColor);
  drawData.shadowColor = &shadowColor;
  drawData.drawColinearityLines = TRUE;
  g_list_foreach(bc->selectedSeqs, drawSequenceMspLines, &drawData);
  
  g_object_unref(gc);
}


/* Main function that does the drawing for the grid. Drawing is done onto a pixmap
 * which is then stored in the grid properties */
static void drawBigPictureGrid(GtkWidget *grid, GdkDrawable *drawable)
{
  GridProperties *properties = gridGetProperties(grid);
  BigPictureProperties *bpProperties = bigPictureGetProperties(properties->bigPicture);
  BlxContext *bc = bigPictureGetContext(properties->bigPicture);

  /* Calculate some factors for scaling */
  const gdouble percentPerCell = bigPictureGetIdPerCell(properties->bigPicture);
  const gint numVCells = gridGetNumVCells(grid);

  /* Highlight any regions that are assembly gaps */
  /* Get the display range in dna coords */
  IntRange bpRange;
  convertDisplayRangeToDnaRange(&bpProperties->displayRange, bc->seqType, bc->numFrames, bc->displayRev, &bc->refSeqRange, &bpRange);
  
  GdkColor *color = getGdkColor(BLXCOLOR_ASSEMBLY_GAP, bc->defaultColors, FALSE, bc->usePrintColors);

  drawAssemblyGaps(grid, drawable, color, bc->displayRev,
                   &properties->gridRect, &bpRange, 
                   bc->featureLists[BLXMSP_GAP]);
  
  /* Draw the grid lines */
  drawVerticalGridLines(&properties->gridRect, &properties->highlightRect, properties->gridYPadding, bc, bpProperties, drawable);
  drawHorizontalGridLines(grid, properties->bigPicture, &properties->gridRect, bc, bpProperties, drawable, numVCells, percentPerCell, bpProperties->percentIdRange.max, FALSE, "%");
  
  /* Draw lines corresponding to the MSPs */
  drawMspLines(grid, drawable);
}


/* Prepare the grid for printing (draws the transient hightlight box
 * onto the cached drawable). */
void gridPrepareForPrinting(GtkWidget *grid)
{
  GdkDrawable *drawable = widgetGetDrawable(grid);
  
  if (drawable)
    {
      GridProperties *properties = gridGetProperties(grid);
      BlxContext *bc = bigPictureGetContext(properties->bigPicture);

      GdkColor *highlightBoxColor = getGdkColor(BLXCOLOR_HIGHLIGHT_BOX, bc->defaultColors, FALSE, bc->usePrintColors);
      drawHighlightBox(drawable, &properties->highlightRect, HIGHLIGHT_BOX_MIN_WIDTH, highlightBoxColor);
    }
}


void calculateGridHighlightBoxBorders(GtkWidget *grid)
{
  GridProperties *properties = gridGetProperties(grid);
  g_return_if_fail(properties);

  BlxContext *bc = gridGetContext(grid);
  GtkWidget *bigPicture = properties->bigPicture;
  GtkWidget *detailView = bigPictureGetDetailView(bigPicture);

  IntRange *bpRange = bigPictureGetDisplayRange(bigPicture);
  IntRange *dvRange = detailViewGetDisplayRange(detailView);

  bc->highlightBoxCalcBorders(&properties->gridRect,
                              &properties->highlightRect, 
                              bpRange,
                              dvRange,
                              properties->mspLineHeight);
}


/* Calculate the borders for the big picture view */
void calculateGridBorders(GtkWidget *grid)
{
  GridProperties *properties = gridGetProperties(grid);
  BigPictureProperties *bigPictureProperties = bigPictureGetProperties(properties->bigPicture);
  int numVCells = gridGetNumVCells(grid);
  
  /* Get some info about the size of the layout and the font used */
  guint layoutWidth, layoutHeight;
  gtk_layout_get_size(GTK_LAYOUT(grid), &layoutWidth, &layoutHeight);
  
  properties->displayRect.x = 0;
  properties->displayRect.y = 0;
  properties->displayRect.width = grid->allocation.width;
  
  /* Get the boundaries of the grid */
  properties->gridRect.x = roundNearest(bigPictureProperties->contentXPos());
  properties->gridRect.y = HIGHLIGHT_BOX_Y_PAD + properties->gridYPadding;
  properties->gridRect.width = bigPictureProperties->contentWidth();
  properties->gridRect.height = bigPictureGetCellHeight(properties->bigPicture) * numVCells;
  
  /* Get the boundaries of the highlight box */
  calculateGridHighlightBoxBorders(grid);
  
  /* Get the total display height required. Set the layout size to fit. */
  const int newHeight = properties->highlightRect.height;
  
  if (newHeight != properties->displayRect.height)
    {
      DEBUG_OUT("Setting new grid height = %d\n", newHeight);
      properties->displayRect.height = newHeight;
      gtk_layout_set_size(GTK_LAYOUT(grid), properties->displayRect.width, properties->displayRect.height);
  
      /* Set the size request to our desired height. We want a fixed heigh but don't set the
       * width, because we want the user to be able to resize that. */
      gtk_widget_set_size_request(grid, 0, properties->displayRect.height);
    }
}


/***********************************************************
 *			    Events			   *
 ***********************************************************/

/* Expose handler for the grid. If the grid has a bitmap cached from the previous
 * call, this function just pushes that back to screen and then (optionally) draws
 * the preview box directly to the window over the top of it. If the cached bitmap
 * is null, this function first calls drawBigPictureGrid to create and cache
 * the bitmap first. */
static gboolean onExposeGrid(GtkWidget *grid, GdkEventExpose *event, gpointer data)
{
  GdkDrawable *window = GTK_LAYOUT(grid)->bin_window;

  if (window)
    {
      GdkDrawable *bitmap = widgetGetDrawable(grid);
      
      if (!bitmap)
        {
          /* There isn't a bitmap yet. Create it now. */
	  bitmap = createBlankPixmap(grid);
          drawBigPictureGrid(grid, bitmap);
        }
      
      if (bitmap)
        {
          /* Push the bitmap onto the window */
          GdkGC *gc = gdk_gc_new(window);
          gdk_draw_drawable(window, gc, bitmap, 0, 0, 0, 0, -1, -1);
          g_object_unref(gc);

          /* Draw the highlight box on top of it */
          GridProperties *properties = gridGetProperties(grid);
          BlxContext *bc = bigPictureGetContext(properties->bigPicture);

          GdkColor *highlightBoxColor = getGdkColor(BLXCOLOR_HIGHLIGHT_BOX, bc->defaultColors, FALSE, bc->usePrintColors);
          drawHighlightBox(window, &properties->highlightRect, HIGHLIGHT_BOX_MIN_WIDTH, highlightBoxColor);
          
          /* Draw the preview box too, if set */
          BigPictureProperties *bpProperties = bigPictureGetProperties(properties->bigPicture);
          bpProperties->drawPreviewBox(window, &properties->gridRect, &properties->highlightRect);
        }
      else
	{
	  g_warning("Failed to draw grid [%p] - could not create bitmap.\n", grid);
	}
    }
  
  return TRUE;
}


/* Re-calculate size info about the given grid following a resize */
static void onSizeAllocateBigPictureGrid(GtkWidget *grid, GtkAllocation *allocation, gpointer data)
{
  DEBUG_ENTER("onSizeAllocateBigPictureGrid");

  /* Recalculate the borders for the grids and the header */
  GridProperties *properties = gridGetProperties(grid);
  BigPictureProperties *bigPictureProperties = bigPictureGetProperties(properties->bigPicture);
  
  calculateGridHeaderBorders(bigPictureProperties->header);
  calculateGridBorders(grid);
  
  DEBUG_EXIT("onSizeAllocateBigPictureGrid returning");
}


/* Mark the given MSP's sequence as selected if this MSP line contains the given coords.
 * Returns true if it was selected. */
static gboolean selectMspIfContainsCoords(GtkWidget *grid, 
					  const MSP *msp,
					  const int x,
					  const int y,
					  gboolean deselectOthers)
{
  gboolean wasSelected = FALSE;
  
  if (mspShownInGrid(msp, grid, TRUE))
    {
      int mspX, mspY, mspWidth, mspHeight;
      calculateMspLineDimensions(grid, msp, TRUE, &mspX, &mspY, &mspWidth, &mspHeight);
      
      if (x >= mspX && x <= mspX + mspWidth && y >= mspY && y <= mspY + mspHeight)
	{
	  /* It's a hit. Select this sequence. */
	  GtkWidget *blxWindow = gridGetBlxWindow(grid);
	  
	  if (deselectOthers)
	    {
	      blxWindowDeselectAllSeqs(blxWindow);
	    }
	  
	  blxWindowSelectSeq(blxWindow, msp->sSequence);
	  
	  /* Update the selected strand */
	  GtkWidget *detailView = blxWindowGetDetailView(blxWindow);
	  detailViewSetSelectedStrand(detailView, gridGetStrand(grid));

	  /* Scroll the detail view trees to bring the new selection into view */
	  callFuncOnAllDetailViewTrees(detailView, treeScrollSelectionIntoView, NULL);

	  wasSelected = TRUE;
	}
    }
  
  return wasSelected;
}


/* Loop through all the msp lines for this grid and mark them as selected
 * if they contain the coords of the mouse press */
static gboolean selectClickedMspLines(GtkWidget *grid, GdkEventButton *event, const gboolean ctrlModifier, const gboolean shiftModifier)
{
  /* Loop through all the MSPs until we find one under the click coords */
  GtkWidget *blxWindow = gridGetBlxWindow(grid);
  const MSP *msp = blxWindowGetMspList(blxWindow);
  const gboolean deselectOthers = !ctrlModifier && !shiftModifier; /* whether to deselect all others first */
  gboolean found = FALSE;

  for ( ; msp && !found; msp = msp->next)
    {
      found = selectMspIfContainsCoords(grid, msp, event->x, event->y, deselectOthers);
    }

  return found;
}


static gboolean onButtonPressGrid(GtkWidget *grid, GdkEventButton *event, gpointer data)
{
  gboolean handled = FALSE;
  
  /* left button */
  if (event->button == 1)
    {
      /* If we clicked on top of an msp line, select that msp */
      const gboolean ctrlModifier = (event->state & GDK_CONTROL_MASK) == GDK_CONTROL_MASK;
      const gboolean shiftModifier = (event->state & GDK_SHIFT_MASK) == GDK_SHIFT_MASK;
      
      handled = selectClickedMspLines(grid, event, ctrlModifier, shiftModifier);
    }
  
  /* Middle button: always show the preview box; left button: show
   * preview box if we double-clicked, or if we clicked in the highlight
   * box (i.e. left button selects and drags the highlight box; middle 
   * button or double-click makes the highlight box jump) */
  GridProperties *properties = gridGetProperties(grid);
  
  if (event->button == 2 || 
      (event->button == 1 && !handled && 
       (event->type == GDK_2BUTTON_PRESS || 
        clickedInRect(event, &properties->highlightRect, HIGHLIGHT_BOX_MIN_WIDTH))))
    {
      /* If dragging the highlight box (left button), then centre the preview 
       * box on the existing highlight box centre; otherwise, centre it on the click pos */
      int x = event->x;
      
      if (event->button == 1 && event->type == GDK_BUTTON_PRESS)
        x = properties->highlightRect.x + properties->highlightRect.width / 2;

      BigPictureProperties *bpProperties = bigPictureGetProperties(properties->bigPicture);
      bpProperties->startPreviewBox(event->x, TRUE, x - event->x);
      handled = TRUE;
    }
  
  return handled;
}


static gboolean onButtonReleaseGrid(GtkWidget *grid, GdkEventButton *event, gpointer data)
{
  if (event->button == 1 || event->button == 2) /* left or middle button */
    {
      GridProperties *properties = gridGetProperties(grid);
      BigPictureProperties *bpProperties = bigPictureGetProperties(properties->bigPicture);
      bpProperties->finishPreviewBox(event->x, &properties->gridRect, &properties->highlightRect);
    }
  
  return TRUE;
}


/* Implement custom scrolling for horizontal mouse wheel movements over the grid.
 * This scrolls the position of the highlight box, i.e. it scrolls the display
 * range in the detail view. */
static gboolean onScrollGrid(GtkWidget *grid, GdkEventScroll *event, gpointer data)
{
  gboolean handled = FALSE;
  
  switch (event->direction)
    {
      case GDK_SCROLL_LEFT:
	{
          scrollBigPictureLeftStep(gridGetBigPicture(grid));
	  handled = TRUE;
	  break;
	}
	
      case GDK_SCROLL_RIGHT:
	{
          scrollBigPictureRightStep(gridGetBigPicture(grid));
	  handled = TRUE;
	  break;
	}

      default:
	{
	  handled = FALSE;
	  break;
	}
    };
  
  return handled;
}


static gboolean onMouseMoveGrid(GtkWidget *grid, GdkEventMotion *event, gpointer data)
{
  if ((event->state & GDK_BUTTON1_MASK) || /* left button */
      (event->state & GDK_BUTTON2_MASK))   /* middle button */
    {
      /* Draw a preview box at the mouse pointer location */
      BigPictureProperties *bpProperties = bigPictureGetProperties(gridGetBigPicture(grid));
      bpProperties->startPreviewBox(event->x, FALSE, 0);
    }
  
  return TRUE;
}


/***********************************************************
 *                       Properties                        *
 ***********************************************************/

GridProperties* gridGetProperties(GtkWidget *widget)
{
  return widget ? (GridProperties*)(g_object_get_data(G_OBJECT(widget), "GridProperties")) : NULL;
}

static BlxContext* gridGetContext(GtkWidget *grid)
{
  GtkWidget *blxWindow = gridGetBlxWindow(grid);
  return blxWindowGetContext(blxWindow);
}

static void onDestroyGrid(GtkWidget *widget)
{
  GridProperties *properties = gridGetProperties(widget);
  
  if (properties)
    {
      delete properties;
      properties = NULL;
      g_object_set_data(G_OBJECT(widget), "GridProperties", NULL);
    }
}


GridProperties::GridProperties(GtkWidget *widget_in, 
                               GtkWidget *bigPicture_in,
                               gulong exposeHandlerId_in,
                               BlxStrand strand_in)
  : widget(widget_in),
    bigPicture(bigPicture_in),
    strand(strand_in),
    mspLineHeight(DEFAULT_MSP_LINE_HEIGHT),
    gridYPadding(DEFAULT_GRID_Y_PADDING),
    exposeHandlerId(exposeHandlerId_in),
    ignoreSizeAlloc(FALSE)
{
  gridRect.x = 0;
  gridRect.y = 0;
  gridRect.width = 0;
  gridRect.height = 0;
  displayRect.x = 0;
  displayRect.y = 0;
  displayRect.width = 0;
  displayRect.height = 0;
  highlightRect.x = 0;
  highlightRect.y = 0;
  highlightRect.width = 0;
  highlightRect.height = 0;
}


static void gridCreateProperties(GtkWidget *widget, 
				 GtkWidget *bigPicture,
				 gulong exposeHandlerId,
				 BlxStrand strand)
{
  if (widget)
    { 
      /* Work out how many characters we need to display in the left border for
       * the vertical grid axis label.  This is the number of digits in the 
       * largest label value plus one (for a '%' character)
       * Add a fudge factor to give more space to allow for the fact that 
       * the calculated char width is approximate and may not give enough space */
      GridProperties *properties = new GridProperties(widget, 
                                                      bigPicture,
                                                      exposeHandlerId,
                                                      strand);
      
      g_object_set_data(G_OBJECT(widget), "GridProperties", properties);
      g_signal_connect(G_OBJECT(widget), "destroy", G_CALLBACK(onDestroyGrid), NULL); 
    }
}


static GtkWidget* gridGetBlxWindow(GtkWidget *grid)
{
  GridProperties *properties = grid ? gridGetProperties(grid) : NULL;
  return properties ? bigPictureGetBlxWindow(properties->bigPicture) : NULL;
}


BlxStrand gridGetStrand(GtkWidget *grid)
{
  GridProperties *properties = gridGetProperties(grid);
  return properties->strand;
}

GtkWidget* gridGetBigPicture(GtkWidget *grid)
{
  GridProperties *properties = gridGetProperties(grid);
  return properties ? properties->bigPicture : NULL;
}

static IntRange* gridGetDisplayRange(GtkWidget *grid)
{
  GtkWidget *bigPicture = gridGetBigPicture(grid);
  return bigPictureGetDisplayRange(bigPicture);
}

static GdkColor *gridGetMspLineColor(GtkWidget *grid, const gboolean selected)
{
  GtkWidget *bigPicture = gridGetBigPicture(grid);
  BlxContext *bc = bigPictureGetContext(bigPicture);
  return getGdkColor(BLXCOLOR_MSP_LINE, bc->defaultColors, selected, bc->usePrintColors);
}

/***********************************************************
 *                     Initialization                      *
 ***********************************************************/

GtkWidget* createBigPictureGrid(GtkWidget *bigPicture, BlxStrand strand)
{
  /* Create a layout area for the grid */
  GtkWidget *grid = gtk_layout_new(NULL, NULL);
  
  /* Grid style properties */
  gtk_widget_set_redraw_on_allocate(grid, FALSE);
  gtk_widget_set_name(grid, BIG_PICTURE_GRID_NAME);
  
  /* Connect signals */
  gtk_widget_add_events(grid, GDK_BUTTON_PRESS_MASK);
  gtk_widget_add_events(grid, GDK_BUTTON_RELEASE_MASK);
  gtk_widget_add_events(grid, GDK_POINTER_MOTION_MASK);
  
  gulong exposeHandlerId = g_signal_connect(G_OBJECT(grid), "expose-event", G_CALLBACK(onExposeGrid), NULL);  
  g_signal_connect(G_OBJECT(grid), "size-allocate",	    G_CALLBACK(onSizeAllocateBigPictureGrid), NULL);
  g_signal_connect(G_OBJECT(grid), "button-press-event",    G_CALLBACK(onButtonPressGrid),	      NULL);
  g_signal_connect(G_OBJECT(grid), "button-release-event",  G_CALLBACK(onButtonReleaseGrid),	      NULL);
  g_signal_connect(G_OBJECT(grid), "motion-notify-event",   G_CALLBACK(onMouseMoveGrid),	      NULL);
  g_signal_connect(G_OBJECT(grid), "scroll-event",	    G_CALLBACK(onScrollGrid),		      NULL);
  
  /* Set required data in the grid. We can't set the tree yet because it hasn't been created yet. */
  gridCreateProperties(grid, bigPicture, exposeHandlerId, strand);
  
  return grid;
}