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'selfDetectable a tumor' means that Tumor has determined an age (d_age !=
NO_TUMOR)
cptIndices: for BC: the bi-rad column index to use given the case's age,
for LC: 0 vector, since the LC dose value is a fixed value in the
configuration file.
iterate()
iterates over d_scenario.nIterations.
calls genCases(), simulating the cases.
genCases()
iterates over nCases. Per case:
caseInit:
initialize case variables like costs, detected etc.
The case's status is set to PRESENT
tumorInfo.cumTotalRisk: computes over all modalities of
all screening ages.
calls Screening::radiationRisk,
calls errRisk1405 for each screening round age, passing it
indices[roundIndex] as the
calls beir7Err for all subsequent ages, updating those
radiationRisk vector elements
tumor.reset: resets the tumor-specific variables, determines
* if a tumor will occur,
* the age at which the tumor will occur (tumorAge).
At this point the tumor diameter has not yet been determined.
The diameter is determined by tumor.characteristics,
d_tumor.selfDetectable() returns true if there is an age where a
tumor develops (tumor.d_age != NO_TUMOR)
preScreen:
if there's selfDetectable a tumor prescreening is performed:
selfDetectable a pre-tumor natural death or a selfDetected
tumor. If so,
--> tumor.characteristics() is called, the tumor's
diameter is computed and the case leaves the
simulation
the status remains PRESENT
or it becomes
LEFT_PRE at the case's natural death age, or
TUMOR_PRE at the tumor induced age of death
screening:
while the case's status is PRESENT, all screening rounds are
performed.
The case may LEAVE with status LEFT_DURING at
* the case's natural death age
* or when an interval cancer is detected
(calls tumor.characteristics)
* or because of a tumor induced death
(status TUMOR_DURING at the tumor's death age).
Otherwise a screening is performed by 'screen':
for all the modalities specified at 'Screening: round:'
* adds the costs,
* if a tumor selfDetectable is present: computes the
tumor characteristics and calls selfDetectableDetect:
* may result in the case leaving the simulation with
status
* LEFT_DURING (at the natural death age)
* or TUMOR_DURING at the tumor caused death age)
* or calls selfDetectableFalsePositive
(only updates statistics).
postScreen:
* if a tumor is present at an age before the case's natural
death age then the case's simulation ends (status TUMOR_POST),
determining the tumor's characteristics (i.e., diameter) and
updating the case's cost with the treatment costs.
* If not, then the case leaves the simulation at the case's natural
death age (status TUMOR_POST).
There may stil be a tumor, in which case its characteristics at the
case's death age are determined.
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