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ENTRY CCHU #type complete
TITLE cytochrome c [validated] - human
ORGANISM #formal_name Homo sapiens #common_name man
DATE 24-Apr-1984 #sequence_revision 30-Sep-1991 #text_change
28-Jul-2000
ACCESSIONS A31764; A05676; I55192; A00001
REFERENCE A31764
#authors Evans, M.J.; Scarpulla, R.C.
#journal Proc. Natl. Acad. Sci. U.S.A. (1988) 85:9625-9629
#title The human somatic cytochrome c gene: two classes of
processed pseudogenes demarcate a period of rapid molecular
evolution.
#cross-references MUID:89071748
#accession A31764
##molecule_type DNA
##residues 1-105 ##label EVA
##cross-references GB:M22877; NID:g181241; PIDN:AAA35732.1;
PID:g181242
REFERENCE A05676
#authors Matsubara, H.; Smith, E.L.
#journal J. Biol. Chem. (1963) 238:2732-2753
#title Human heart cytochrome c. Chymotryptic peptides, tryptic
peptides, and the complete amino acid sequence.
#accession A05676
##molecule_type protein
##residues 2-28;29-46;47-100;101-105 ##label MATS
REFERENCE A00001
#authors Matsubara, H.; Smith, E.L.
#journal J. Biol. Chem. (1962) 237:3575-3576
#title The amino acid sequence of human heart cytochrome c.
#contents annotation
#note 66-Leu is found in 10% of the molecules in pooled protein
REFERENCE I55192
#authors Tanaka, Y.; Ashikari, T.; Shibano, Y.; Amachi, T.;
Yoshizumi, H.; Matsubara, H.
#journal J. Biochem. (1988) 103:954-961
#title Construction of a human cytochrome c gene and its functional
expression in Saccharomyces cerevisiae.
#cross-references MUID:89008207
#accession I55192
##status translated from GB/EMBL/DDBJ
##molecule_type mRNA
##residues 78-105 ##label RES
##cross-references GB:D00265; NID:g2897691; PIDN:BAA00187.1;
PID:g219557
GENETICS
#introns 57/1
CLASSIFICATION #superfamily cytochrome c; cytochrome c homology
KEYWORDS acetylated amino end; chromoprotein; electron transfer;
heme; iron; metalloprotein; mitochondrion; oxidative
phosphorylation; polymorphism; respiratory chain
FEATURE
2-105 #product cytochrome c #status experimental #label
MAT\
5-99 #domain cytochrome c homology #label CYC\
2 #modified_site acetylated amino end (Gly) (in mature
form) #status experimental\
15,18 #binding_site heme (Cys) (covalent) #status
experimental\
19,81 #binding_site heme iron (His, Met) (axial ligands)
#status predicted
SUMMARY #length 105 #molecular-weight 11749 #checksum 3247
SEQUENCE
5 10 15 20 25 30
1 M G D V E K G K K I F I M K C S Q C H T V E K G G K H K T G
31 P N L H G L F G R K T G Q A P G Y S Y T A A N K N K G I I W
61 G E D T L M E Y L E N P K K Y I P G T K M I F V G I K K K E
91 E R A D L I A Y L K K A T N E
///
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