1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
|
#NEXUS
[!Alignment of:]
[Sequence Start End Sequencetype]
[btdDm (30 > 414) PROTEIN]
[TSp1 (27 > 398) PROTEIN]
[DSP1 (14 > 444) PROTEIN]
[ostMm (7 > 374) PROTEIN]
[Gg (190 > 694) PROTEIN]
[Hosim (7 > 401) PROTEIN]
[HsSp1 (1 > 706) PROTEIN]
[Sp3mm (143 > 648) PROTEIN]
[HsSp4 (1 > 730) PROTEIN]
[SP5mm (23 > 379) PROTEIN]
[SP6mm (11 > 413) PROTEIN]
[SP7Hs (7 > 377) PROTEIN]
[TIEG1 (58 > 452) PROTEIN]
[Tieg2 (65 > 477) PROTEIN]
[UKLF (38 > 302) PROTEIN]
[EZF (41 > 470) PROTEIN]
[BTEB2 (1 > 218) PROTEIN]
[rattus8can (113 > 513) PROTEIN]
[Sp2-Hs (1 > 606) PROTEIN]
begin data;
dimensions ntax=19 nchar=929;
format datatype=Protein interleave gap=- missing='.';
matrix
[ 1 60]
btdDm ------------------------------------------------------------
TSp1 ------------------------------------------------------------
DSP1 ------------------------------------------------------------
ostMm ------------------------------------------------------------
Gg ------------------------------------------------------------
Hosim ------------------------------------------------------------
HsSp1 QDHSMDEMTAVVKIEKGVGGNNGGNGNGGGAFSQARSSSTGSSSSTGGGGQESQPSPLAL
Sp3mm ------------------------------------------------------------
HsSp4 -------MSDQKKEEEEEAAAAAAMATEGGKTSEPENNNKKPKT---SGSQDSQPSPLAL
SP5mm ------------------------------------------------------------
SP6mm ------------------------------------------------------------
SP7Hs ------------------------------------------------------------
TIEG1 ------------------------------------------------------------
Tieg2 ------------------------------------------------------------
UKLF ------------------------------------------------------------
EZF ------------------------------------------------------------
BTEB2 ------------------------------------------------------------
rattus8can -------------------------------------------------GKGDQIKVTTQ
Sp2-Hs ------------------------------------------------------------
[ 61 120]
btdDm ------------AQQQQHHLHMQQAQHH----------------LHLSH------QQAQQ
TSp1 -------------------------AEH----------------PSLR--------GTPL
DSP1 -------------------------QDH----------------PSLR--------GTPL
ostMm -------------------------EEE----------------AHYG--------SSPL
Gg --------------QETGQIQIIPGSNQ----------------TIIAS-------GSPS
Hosim -------------------------GEE----------------PRLG--------STPL
HsSp1 LAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSS----GATPT
Sp3mm --------------QENSQIQIIPGSNQ----------------TLLAS-------GTPP
HsSp4 LAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPP
SP5mm --------------------------AS----------------PDLG-------KHSPL
SP6mm -------------------PPAASRRVW----------------LALG--------SCPL
SP7Hs -------------------------EEE----------------VHYG--------SSPL
TIEG1 --------------KYVENRPVTPVS---------------------D--------LSEE
Tieg2 --------------DLLRIRPLTPVSDS------------------GD--------VTTT
UKLF --------------ELERYLQTEPRR------------------------------ISET
EZF --------------HMKRLPPVLPGRPY------------------DL--------AAAT
BTEB2 ----------------------MPSS------------------------------TNQT
rattus8can RRRRTLAPYRYPLPIFLFDRNIRKRKEE----------------PRLG--------STPL
Sp2-Hs ----------MAATAAVSPSDYLQPAAS----------------TTQDS------QPSPL
[ 121 180]
btdDm QHMQHLTQQ--------------QQQQQQQQQQQ-----------QQ---------QQQQ
TSp1 AMLAAQCNK------------LSNKSPPP--LAD-----AAVGK-GF---------HPWK
DSP1 AMLAAQCNK------------LSNKSPPP--LAD-----AAVGK-GF---------HPWK
ostMm AMLTAACSK------------FGGSSP----LRDS----TTLGK-GG---------TKKP
Gg ANIQNILSQ------------SGQVQVQGVAIGG-----SSFPG-QA---------QVVA
Hosim AMLAATCNK------------IGSPSPSPSSLSDSS---SSFGK-GF---------HPWK
HsSp1 SKEQSGSSTNGS---------NGSESSKNRTVSGGQYVVAAAPNLQN---------QQVL
Sp3mm ANIQNLIPQ------------TGQVQVQGVAIGG-----SSFPG-QT---------QVVA
HsSp4 ASKENNVSQPASSSSSSSSSNNGSASPTKTKSGN-----SSTPG-QF---------QVIQ
SP5mm ALLAATCSR------------IGQPGAAAAPDFLQ---------------------VPYD
SP6mm PLESSPAHR------------AYERPS----VAHQ----PAVPG-AR---------RSLE
SP7Hs AMLTAACSK------------FGGSSP----LRDS----TTLGK-AG---------TKKP
TIEG1 ENLLPGTP------------DFHTIPAFCLTPPYSP---SDFEP-SQ---------VSNL
Tieg2 VHMDAATPELPK--------DFHSLSTLCITPPQSP---DLVEP-STRTP------VSPQ
UKLF FGEDLDCF-------------LHASPPPC---------------------------IEES
EZF VATDLESG-------------GAGAACGGSNLAPLP---RRETE-EFNDLLDLDFILSNS
BTEB2 AAMDTLNV-------------SMSAAMAG---------------------------LN--
rattus8can AMLAATCNK------------IGSPSPSPSSLSDSS---SSFSK-GF---------HPWK
Sp2-Hs ALLAATCSK------------IGPPAVEAAVTPPAPP--QPTPR-KL---------VPIK
[ 181 240]
btdDm QQQP------------------------------QQQ-QHDFLSAAAL------------
TSp1 KSPQ------------------------------GAPSPSTTPSS--LPTQRTST-----
DSP1 KSPNSPAAGSSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGGQSSRSLSS-----
ostMm Y--------------------------------ADLSAPKTMGDAYPAPFSSTNG-----
Gg N-VP--LG--------------------------LPG-NITFVPINSVDLDSLG------
Hosim RSSSS-----------------------------SSASCNVVGSS--LSSFGVSG-----
HsSp1 TGLPGVMPNIQYQVIPQ--------------FQTVDGQQLQFAATGAQVQQDGSGQIQII
Sp3mm N-VP--LG--------------------------LPG-NITFVPINSVDLDSLG------
HsSp4 VQNP--SGSVQYQVIPQ--------------LQTVEGQQIQINPTSSSSLQDLQGQIKLI
SP5mm PA--------------------------------LGSPSRLFHPWTADMPAHSPG-----
SP6mm VPSE-----------------------------VPLTVPALTPPRIPAMLTAVCG-----
SP7Hs YSVG-----------------------------SDLSASKTMGDAYPAPFTSTNG-----
TIEG1 MAPA------------------------------PSTVHFKSLSDTAKPHIAAPF-----
Tieg2 VTDS------------------------------KACTATDVLQSSAVVARALSG-----
UKLF FRR-------------------------------LDPLLLPVEAAICEKSSAVD------
EZF LTHP------------------------------PESVAATVSSSASASSSSSPS-----
BTEB2 -TH--------------------------------TS---AVPQTAVKQFQGMP------
rattus8can RSSSS-----------------------------SSGSCNVVGSS--LSSFGVSG-----
Sp2-Hs PAPLPLSPGK--NSFG-----------------ILSSKGNILQIQGSQLSASYPGGQLV-
[ 241 300]
btdDm ----------------------------------LSAP----------------------
TSp1 ---------SNPTYS----------------SRSVMTS-------C--------------
DSP1 ---------SASTMVNIT------------ASRPLASS-------C--------------
ostMm ---------LLS----------------------PAGS-------P--------------
Gg --------LGSGSQT---------------MTAGINAD----------------------
Hosim ---------ASRNGG----------------SSSAAAA-------A--------------
HsSp1 PGAN---QQIITNRG---------------SGGNIIAAMPNLLQQAVPLQG-----LANN
Sp3mm --------LSGSSQT---------------MTAGINAD----------------------
HsSp4 SAGNNQAILTAANRT---------------ASGNILAQNLANQTVPVQIRPGVSIPLQLQ
SP5mm ---------ALPPP-----------------HPSLGLT-PQKTHLQ--------------
SP6mm ---------SLGSQH----------------TEAPHAS-------P--------------
SP7Hs ---------LLS----------------------PAGS-------P--------------
TIEG1 ---------KEEE-------------------KSPVSA----------------------
Tieg2 ---------GAERG-----------------LLGLEPV----------------------
UKLF ---------------------------------ILLSR----------------------
EZF ---------SSGPASA--------------PSTCSFTY----------------------
BTEB2 ------------P--------------------CTYTM----------------------
rattus8can ---------ASRNG----------------------------------------------
Sp2-Hs --------FAIQNPTMINKGTRSNANIQYQAVPQIQASNSQTIQVQ--------------
[ 301 360]
btdDm ------------------------PSLS----------------GSSSGSSSGSS--PLY
TSp1 ------------------------SSVP---------------------TTASYG-----
DSP1 ------------------------AAVGGGSTGSSSSASGSQSSSTASAVAAAYG-----
ostMm ------------------------P-----------------------APASGYA-----
Gg -----------------G------HLIN----------TGQAMDSSDNSERTGEQVSPEI
Hosim ------------------------AAAA--------------------AAAAALV-----
HsSp1 VLSGQTQYVTNVPVALNG--NITLLPVNSVSAATLTP-SSQAVTISSSGSQESGSQPVTS
Sp3mm -----------------G------HLIN----------TGQAMDSSDNSERTGERVSPDV
HsSp4 TLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGGTGQVGQPAATADSGTSNGNQLVSTP
SP5mm ------------------------PSFG---------------AAHELPLTPPAD-----
SP6mm ------------------------PRLD------------LQPLQTYQGHTSPEA-----
SP7Hs ------------------------P-----------------------APTSGYA-----
TIEG1 ------------------------PKLP----------------KAQATSVIRHT----A
Tieg2 ------------------------PSSPC---------------RAKGTSVIRHT----G
UKLF ------------------------DK----------------------------------
EZF ------------------------PIRAGN-----------DPGVAPGGTGGGLL----Y
BTEB2 ------------------------PS----------------------------------
rattus8can ------------------------------------------------------------
Sp2-Hs ------------------------PNLTNQIQ--------IIPGTNQAIITPSPS-----
[ 361 420]
btdDm GKPPMKLELPYPQASS-----------TGTASPNSSIQSAPSSA------SVSPSIFPS-
TSp1 SDLYFPGATS-QPPTD----------NSHVHHHQTSLLGKVEG--------AATHHLGS-
DSP1 GDLYFP-NTS-TSNMD----------N---HHMHQGLLGKVE---------AGAAAFGG-
ostMm NDYP-PFP----HSFP----------GPTGAQDPGLLVPKG---------HSSSDCLPS-
Gg TETATDNDLFVPTSSSSQLPVTID--SSSILEQNANNLTTTSGQ------VHSSDLQGN-
Hosim SDSFSCGGSS-AHSQD----------G----SHQPVFISKVH---------TSVDGLQG-
HsSp1 GTTISSASLVSSQASSSSFFTNANSYSTTTTTSNMGIMNFTTSG------SSGTNSQGQ-
Sp3mm NETNADTDLFVPTSSSSQLPVTID--STGILQQNTNSLTTTSGQ------VHSSDLQGN-
HsSp4 TNTTTSASTMPESPSSSTTCTTTA--STSLTSSDTLVSSADTGQ------YASTSASSSE
SP5mm PSYPYEFSPVKMLPSSM---------AALPASCAPAYVPYAAQA----------ALPPG-
SP6mm GDYPSPLQPGELQSLPL---------GPEVDFSQGYELPGASSRVTCEDLESDSPLAPG-
SP7Hs NDYP-PFS----HSFP----------GPTGTQDPGLLVPKG---------HSSSDCLPS-
TIEG1 DAQLCNHQTCPMKAAS----------ILNYQNNSFRRRTHLNVE------AARKNIPCA-
Tieg2 ESPAACFPTIQTPDCR----------LSDSREGEEQLLGHFETL------QD-THLTDS-
UKLF ---------------------------------------LLS--------ETCLSLQP--
EZF GRESAPPPTAPFNLAD----------INDVSPSGGFVAELLRPE------LDPVYIPPQ-
BTEB2 --------------------------------------QFLP--------QQATYFPP--
rattus8can -----------AHSQD----------S----SHQPVFISKVH---------TSVDGLQG-
Sp2-Hs SHKPVPIKPAPIQKSST---------TTTPVQSGANVVKLTGGGG-----NVTLTLPVNN
[ 421 480]
btdDm ------------------------------------------------------------
TSp1 ---------------------------------------------------------VYS
DSP1 ---------------------------------------------------------VYS
ostMm ---------------------------------------------------------VYT
Gg ----YIQTSVSDDTQAQN--------IQVSTAQP-------IVQHIQLQESQQP--TSQA
Hosim ---------------------------------------------------------IYP
HsSp1 ---TPQRVSGLQGSDALN--------IQQNQTSGGSLQAGQQKEGEQNQQTQQQQILIQP
Sp3mm ----YIQSPVSEETQAQN--------IQVSTAQP-------VVQHLQLQDSQQP--TSQA
HsSp4 RTIEESQTPAATESEAQSSSQLHANGMQNQQDQSNSLQQVQIVGQPILQQIQIQ--QPQQ
SP5mm ----------------------------------------------------------YS
SP6mm ---------------------------------------------------------PFS
SP7Hs ---------------------------------------------------------VYT
TIEG1 ---------------------------------------------------------AVS
Tieg2 ---------------------------------------------------------LLS
UKLF ------------------------------------------------------------
EZF ---------------------------------------------------------QPQ
BTEB2 ------------------------------------------------------------
rattus8can ---------------------------------------------------------IYP
Sp2-Hs -------------------------------------------------LVNASDTGAPT
[ 481 540]
btdDm -------PAQSFAS------------ISAS----P----------STPTTTLAPPTTAAA
TSp1 R--------HPYES-----------WPFN-----TMSGATHHGG--I-----KSDSV-TS
DSP1 R--------HPYD------------WPFN--------AVTHK----------EAASV-NS
ostMm SL----DMTHPYGS-----------WYKAG----IHAGISPGP----------GNTP-TP
Gg QIVQG-IAQQTIHG---VQAS---QSISPQ----ALQNLQLQ-L-NPGTFLIQAQTVTPS
Hosim RV----GMAHPYES-----------WFKP-----SHPGLGAAG---------EVGSA-GA
HsSp1 QLVQGGQALQALQAAPLSGQTFTTQAISQE----TLQNLQLQAVPNSGPIIIRTPTVGPN
Sp3mm QIVQG-ITPQTIHG---VQASG--QNISQQ----ALQNLQLQ-L-NPGTFLIQAQTVTPS
HsSp4 QIIQA-IPPQSFQLQ--SGQTI--QTIQQQ----PLQNVQLQAV-NPTQVLIRAPTLTPS
SP5mm NLLPP-PPPPPPPP-----------TCRQL----SPAPAPDDLP----------------
SP6mm KLLQP-DMSHHYES-----------WFRP-----THPGAEDG-------------S----
SP7Hs SL----DMTHPYGS-----------WYKAG----IHAGISPGP----------GNTP-TP
TIEG1 P------NRSKCER----------NTVAD----VDEKASAAL----------YDFSVPSS
Tieg2 T------NLVSCQP----------CLHKSGGLLLTDKGQQAG----------WPGAVQTC
UKLF ----------------------------------ASSSLD-------------------S
EZF P------PGGGLMG----------KFVLKAS--LSAPGSEYG----------SPSVISVS
BTEB2 ----------------------------------SPPSSE-------------P------
rattus8can RV----GMAHPYES-----------WFKP-----SHPGLGAAA---------DVGSA-GA
Sp2-Hs QLLTE-SPPTPLSK-----------TNKKA----RKKSLPASQP--PVAVAEQVETVLIE
[ 541 600]
btdDm G-------ALAGSP-------------------TSSSPSSS------------AASAAAA
TSp1 N--AWWDVHS------------------T--GSWLDMSG----------------GMH-Q
DSP1 ---GWWDMHS-----------------AA--GSWLDMGG---A------------GMHST
ostMm ----WWDMHPGGNWL---GGGQGQGDGLQ--GTLSTGPAQP--------------PLNPQ
Gg GQITWQTFQVQGVQN--LQNLQIQNA-PG--QQITLTPVQT-----------LTLGQVAA
Hosim S--SWWDVGAGWIDV---QNPNSAA-ALP--GSLHPAAGGLQT------------SLHSP
HsSp1 GQVSWQTLQLQNLQ---VQNPQAQTITLAPMQGVSLGQTSSSN---------TTLTPIAS
Sp3mm GQITWQTFQVQGVQN--LQNLQIQNT-AA--QQITLTPVQT-----------LTLGQVAA
HsSp4 GQISWQTVQVQNIQS--LSNLQVQNAGLS--QQLTITPVSSSGG--------TTLAQIAP
SP5mm ----WWSIPQSG------AGPGSSG-----------VPGTS---------------LSSA
SP6mm ----WWDLHPGTSWM---DLPHTQG-------ALTS-PGHPG-------------ALQAG
SP7Hs ----WWDMHPGGNWL---GGGQGQGDGLQ--GTLPTGPAQP--------------PLNPQ
TIEG1 ------ETVICRSQP---APVSPQQ------KSVLVSPPA---------------VSAGG
Tieg2 ------SPKNYENDL---PRKTTPL------ISVSVPAPP---------------VLCQM
UKLF ------YTAVN------------Q-------------------------------AQLNA
EZF ------KGSPDGSHP---VVVAPYN------GGPPRTCPK---------------IKQEA
BTEB2 -------GSPD------------R--------------------------------QAEM
rattus8can S--SWWDVGAGWIDV---QNPNGAA-ALP--GSLHPAAGGLQT------------SLHSP
Sp2-Hs T--TADNIIQAGNNLLIVQSPGGGQPAVV--QQVQVVPPKAEQQQVVQIPQQALRVVQAA
[ 601 660]
btdDm AAAAAAAAADLGAAAVASA------------------AYGWNTAYSGLGPARSQFP----
TSp1 MANYSTDYSSL--------------------------THSLAASNHLLSSG--QHLL---
DSP1 MANYASEN------------------------------YSSALSHSLLGSG--QHLL---
ostMm LPTYPSDFAPLN-------------------------PAPYPAPHLLQPGP--QHVL---
Gg GGALTSTPVSLSTAQLP---------------------NLQTVTVNSIDSAGIQLH----
Hosim LGGYNSDYSGLSHS-----------------------AFSSGASSHLLSPA--GQHL---
HsSp1 AASIPAGTVTVNAAQLSSM------------------PGLQTINLSALGTSGIQVH----
Sp3mm GGALTSTPVSLSTGQLP---------------------NLQTVTVNSIDSTGIQLH----
HsSp4 -VAVAGAPITLNTAQLASV------------------PNLQTVSVANLGAAGVQVQGVPV
SP5mm CAGPPHAPRFPAS----------------------------AAAAAAAAAALQRGLVL--
SP6mm LGGYVGDHQLCA-------------------------PPPHPHAHHLLPAAGGQHLLG--
SP7Hs LPTYPSDFAPLN-------------------------PAPYPAPHLLQPGP--QHVL---
TIEG1 VPPMPVICQMVPLP--A--------------------NNPVVTTVVPSTPPSQPPAVC--
Tieg2 IP-VTGQSSMLPAF--L--------------------KPPPQLSVGTVRPILAQAAPA--
UKLF VTSLT-----PP------------------------------SS---------PELSR--
EZF VSSCTHLGAGPPLS--N--------------------GHRPAAHNFPLGRQL-PSRST--
BTEB2 LQNLT-----PP------------------------------PS----------------
rattus8can LGGYNSDYSGLSHS-----------------------AFSSGASSHLLSPA--GQHL---
Sp2-Hs SATLPTVPQKPSQNFQIQAAEPTPTQVYIRTPSGEVQTVLVQDSPPATAAATSNTTCS--
[ 661 720]
btdDm -------YAQYASDYYGNAVGMSSSAAWFSHQER--------LYQPWSSQSYPGFN----
TSp1 ------------QDTYKSMLPGAQT---VGASFG---------LHATGSAPSPTAG----
DSP1 ------------QDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAA----
ostMm -----------PQDVYKPKAVGNSG-----QLEG----------SGAAKPPRGAG-----
Gg -----QGENAGSPADIRIKEEEPDPEEWQLSGDS-----TLNTNDLTHLRVQVVDE----
Hosim ------------MDGFKPVLPGSYPDSAPSPLAG---------AGGSMLSAGPSAP----
HsSp1 -------PIQGLPLAIANAPGDHG-AQLGLHGAG------GDGIHDDTAGGEEGEN----
Sp3mm -----PGENADSPADIRIKEEEPDPEEWQLSGDS-----TLNTNDLTHLRVQVVDE----
HsSp4 TITSVAGQQQGQ-DGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQ----
SP5mm -----------GPSDFAQYQS---------QIAA---------LLQTKAPLAATA-----
SP6mm -----------PPDGAKALEVAAP--------ES----------QGLDSSLDGAAR----
SP7Hs -----------PQDVYKPKAVGNSG-----QLEG----------SGGAKPPRGAS-----
TIEG1 -----------PPVVFMGTQVPKG-AVMFVVPQP--------VVQSSKP---PVVS----
Tieg2 -----------PQPVFVGPAVPQG-AVMLVLPQG--------ALPPPAPCAANVMA----
UKLF -----------HLVKTSQTLSAVDGTVTLKLVAK--------KAALSSVKVGGVAT----
EZF -----------PTLGFEEVLSSRECHPALPLPPG--------FHPHPGPNYPSFLP----
BTEB2 ---------------YAATIASK-----LAIHN---------------PNLPTTLP----
rattus8can ------------MDGFKPVLPGSYPDSAPSPLAG---------AGSSMLSAGPAAP----
Sp2-Hs -----------SPASRAPHLSGTSK----KHSAA---------ILRKERPLPKIAPAGSI
[ 721 780]
btdDm ----------------------------------FDDIA---------------------
TSp1 ----------------------------------AGGLP---------------------
DSP1 ----------------------------------AGGSPQ--------------------
ostMm ----------------------------------TGGSG---------------------
Gg ----------------------------------EGDQP---------------------
Hosim ----------------------------------LGGSP---------------------
HsSp1 ----------------------------------SPDAQ---------------------
Sp3mm ----------------------------------EGDQQ---------------------
HsSp4 ----------------------------------TSDQE---------------------
SP5mm ------------------------------------------------------------
SP6mm ----------------------------------PKGSR---------------------
SP7Hs ----------------------------------TGGSG---------------------
TIEG1 ----------------------------------PNGT----------------------
Tieg2 ----------------------------------AGNT----------------------
UKLF ----------------------------------AAAAV---------------------
EZF ----------------------------------DQMQP---------------------
BTEB2 ----------------------------------VNSQ----------------------
rattus8can ----------------------------------LGGSP---------------------
Sp2-Hs ISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQ
[ 781 840]
btdDm ------------FQTQLQRRSVRCTCPNCTN-EMSGLPPIVGPDE--RGRK--------Q
TSp1 ------PQVPSPRSQRRYTGRATCDCPNCQEAERLGP----AGVH--LRKKN-------I
DSP1 ---GGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGP----AGVH--LRKKN-------I
ostMm ------------GYAGSGAGRSTCDCPNCQELERLGA----AAA--GLRKKP-------I
Gg ------------HQEGKRLRRVACTCPNCK--EGGGR----GSN---LGKKK-------Q
Hosim ------R-----SSARRYSGRATCDCPNCQEAERLGP----AGAS--LRRKG-------L
HsSp1 ------------PQAGRRTRREACTCPYCK--DSEGR----GSGD--PGKKK-------Q
Sp3mm ------------HQEGKRLRRVACTCPNCK--EGGGR----GTN---LGKKK-------Q
HsSp4 ------------VQPGKRLRRVACSCPNCR--EGEGR----GSNE--PGKKK-------Q
SP5mm ------------------RRCRRCRCPNCQAAGGAPE----AEP----GKKK-------Q
SP6mm ------------RSVPRSSGQTVCRCPNCLEAERLGA----PCGPDGGKKKH-------L
SP7Hs ------------GYGGSGAGRSSCDCPNCQELERLGA----AAA--GLRKKP-------I
TIEG1 --------------RLSPIAPAPGFSPSAAKVTPQID-----SS----RIR--------S
Tieg2 --------------KLLPLAPAPVFITSSQNCVPQVD-----FS----RRR--------N
UKLF -------------TAAGAVKSGQSDSDQGGLGAEACP-----EN----KKR--------V
EZF --------------QVPPLHYQELMPPGSCMPEEPKP-----KR----GRRSWPRKRTAT
BTEB2 --------------NIQPVRYNRRSNP--DL-EK---------------RR--------I
rattus8can ------R-----SSARRYSGRATCDCPNCQEAERLGP----AGAS--LRRKG-------L
Sp2-Hs IQLQMEQALAGETQPGEKRRRMACTCPNCKD-GEKRS----GEQ----GKKK--------
[ 841 900]
btdDm HICHIPGCERLYGKASHLKTHLRWHTGERPFLC--LTCGKRFSRSDELQRHGRTHTNYRP
TSp1 HSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKR
DSP1 HSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKR
ostMm HSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKK
Gg HICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCNWMFCGKRFTRSDELQRHRRTHTGEKK
Hosim HSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKR
HsSp1 HICHIQGCGKVYGKTSHLRAHLRWHTGERPFMCTWSYCGKRFTRSDELQRHKRTHTGEKK
Sp3mm HICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKK
HsSp4 HICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKR
SP5mm HVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKR
SP6mm HNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKK
SP7Hs HSCHIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKK
TIEG1 HICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKK
Tieg2 YVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKK
UKLF HRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKP
EZF HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRP
BTEB2 HYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKP
rattus8can HSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKR
Sp2-Hs HVCHIPDCGKTFRKTSLLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKR
[ 901 929]
btdDm YACPICSKKFSRSDHLSKHKKTHF-----
TSp1 FACPICNKRFMRSDHLAKHVKTHN-----
DSP1 FACPVCNKRFMRSDHLAKHVKTHN-----
ostMm FTCLLCSKRFTRSDHLSKHQRTHG-----
Gg FVCPECSKRFMRSDHLAKHIKTHQ-----
Hosim FACPVCNKRFMRSDHLSKHVKTHS-----
HsSp1 FACPECPKRFMRSDHLSKHIKTHQ-----
Sp3mm FVCPECSKRFMRSDHLAKHIKTHQ-----
HsSp4 FECPECSKRFMRSDHLSKHVKTHQ-----
SP5mm FACPECGKRFMRSDHLAKHVKTHQ-----
SP6mm FPCAVCSRVFMRSDHLAKHMKTHE-----
SP7Hs FTCLLCSKRFTRSDHLSKHQRTHG-----
TIEG1 FACPMCDRRFMRSDHLTKHARRHL-----
Tieg2 FVCPVCDRRFMRSDHLTKHARRHM-----
UKLF FKCNHCDRCFSRSDHLALHMKRHI-----
EZF FQCQKCDRAFSRSDHLALHMKRHF-----
BTEB2 FQCGVCNRSFSRSDHLALHMKRHQ-----
rattus8can FACPVCNKRFMRSDHLSKHVKTHS-----
Sp2-Hs FECAQCQKRFMRSDHLTKHYKTHLVTKNL
;
endblock;
|
