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#!/usr/bin/env perl
use strict;
use warnings;
my $usage = "usage: $0 fpkm.matrix pct_of_top_fpkm\n\n";
my $expr_matrix = $ARGV[0] or die $usage;
my $pct_of_top = $ARGV[1] or die $usage;
main: {
open (my $fh, $expr_matrix) or die $!;
my $header = <$fh>;
chomp $header;
$header =~ s/^\s+//;
my @samples = split(/\t/, $header);
while (<$fh>) {
my ($gene, @vals) = split(/\t/);
my $max_val = &get_max(@vals);
my @within_range;
for (my $i = 0; $i <= $#vals; $i++) {
my $val = $vals[$i];
my $pct_top = 100 - ($val/$max_val * 100);
if ($pct_top <= $pct_of_top) {
push (@within_range, $samples[$i]);
}
}
my $sample_spec_type = join("|", sort @within_range);
print "$gene\t$sample_spec_type\n";
}
close $fh;
exit(0);
}
####
sub get_max {
my @vals = @_;
@vals = sort {$a<=>$b} @vals;
my $max = pop @vals;
return($max);
}
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