File: openslide2vips.c

package info (click to toggle)
vips 8.10.5-2
  • links: PTS
  • area: main
  • in suites: bullseye
  • size: 40,952 kB
  • sloc: ansic: 201,201; cpp: 9,766; sh: 5,031; xml: 4,191; python: 3,869; makefile: 1,033; perl: 40
file content (702 lines) | stat: -rw-r--r-- 18,113 bytes parent folder | download
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
/* Read a virtual microscope slide using OpenSlide.
 *
 * Benjamin Gilbert
 *
 * Copyright (c) 2011-2015 Carnegie Mellon University
 *
 * 26/11/11
 *	- initial version
 * 27/11/11
 *	- fix black background in transparent areas
 *	- no need to set *stop on fill_region() error return
 *	- add OpenSlide properties to image metadata
 *	- consolidate setup into one function
 *	- support reading arbitrary layers
 *	- use VIPS_ARRAY()
 *	- add helper to copy a line of pixels
 *	- support reading associated images
 * 7/12/11
 *	- redirect OpenSlide error logging to vips_error()
 * 8/12/11
 *	- add more exposition to documentation
 * 9/12/11
 * 	- unpack to a tile cache
 * 11/12/11
 * 	- move argb->rgba into conversion
 * 	- turn into a set of read fns ready to be called from a class
 * 28/2/12
 * 	- convert "layer" to "level" where externally visible
 * 9/4/12
 * 	- move argb2rgba back in here, we don't have a use for coded pixels
 * 	- small cleanups
 * 11/4/12
 * 	- fail if both level and associated image are specified
 * 20/9/12
 *	- update openslide_open error handling for 3.3.0 semantics
 *	- switch from deprecated _layer_ functions
 * 11/10/12
 * 	- look for tile-width and tile-height properties
 * 	- use threaded tile cache
 * 6/8/13
 * 	- always output solid (not transparent) pixels
 * 25/1/14
 * 	- use openslide_detect_vendor() on >= 3.4.0
 * 30/7/14
 * 	- add autocrop toggle
 * 9/8/14
 * 	- do argb -> rgba for associated as well 
 * 27/1/15
 * 	- unpremultiplication speedups for fully opaque/transparent pixels
 * 18/1/17
 * 	- reorganise to support invalidate on read error
 * 27/1/18
 * 	- option to attach associated images as metadata
 * 22/6/20 adamu
 * 	- set libvips xres/yres from openslide mpp-x/mpp-y
 */

/*

    This file is part of VIPS.

    VIPS is free software; you can redistribute it and/or modify
    it under the terms of the GNU Lesser General Public License as published by
    the Free Software Foundation; either version 2 of the License, or
    (at your option) any later version.

    This program is distributed in the hope that it will be useful,
    but WITHOUT ANY WARRANTY; without even the implied warranty of
    MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
    GNU Lesser General Public License for more details.

    You should have received a copy of the GNU Lesser General Public License
    along with this program; if not, write to the Free Software
    Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA
    02110-1301  USA

 */

/*
#define VIPS_DEBUG
 */

#ifdef HAVE_CONFIG_H
#include <config.h>
#endif /*HAVE_CONFIG_H*/
#include <vips/intl.h>

#ifdef HAVE_OPENSLIDE

#include <string.h>
#include <stdint.h>
#include <stdlib.h>
#include <limits.h>

#include <vips/vips.h>
#include <vips/debug.h>

#include "pforeign.h"

#include <openslide.h>

typedef struct {
	/* Params.
	 */
	char *filename;
	VipsImage *out;
	int32_t level;
	gboolean autocrop;
	char *associated;
	gboolean attach_associated;

	openslide_t *osr;

	/* Crop to image bounds if @autocrop is set. 
	 */
	VipsRect bounds;

	/* Only valid if associated == NULL.
	 */
	double downsample;
	uint32_t bg;

	/* Try to get these from openslide properties.
	 */
	int tile_width;
	int tile_height;
} ReadSlide;

int
vips__openslide_isslide( const char *filename )
{
#ifdef HAVE_OPENSLIDE_3_4
	const char *vendor;
	int ok;

	vendor = openslide_detect_vendor( filename );

	/* Generic tiled tiff images can be opened by openslide as well.
	 * Only offer to load this file if it's not a generic tiff since
	 * we want vips_tiffload() to handle these.
	 */
	ok = ( vendor &&
		strcmp( vendor, "generic-tiff" ) != 0 );

	VIPS_DEBUG_MSG( "vips__openslide_isslide: %s - %d\n", filename, ok );

	return( ok );
#else
	openslide_t *osr;
	int ok;

	ok = 0;
	osr = openslide_open( filename );

	if( osr ) {
		const char *vendor;

		/* Generic tiled tiff images can be opened by openslide as
		 * well. Only offer to load this file if it's not a generic
		 * tiff since we want vips_tiffload() to handle these.
		 */
		vendor = openslide_get_property_value( osr,
			OPENSLIDE_PROPERTY_NAME_VENDOR );

		/* vendor will be NULL if osr is in error state.
		 */
		if( vendor &&
			strcmp( vendor, "generic-tiff" ) != 0 )
			ok = 1;

		openslide_close( osr );
	} 

	VIPS_DEBUG_MSG( "vips__openslide_isslide: %s - %d\n", filename, ok );

	return( ok );
#endif
}

static void
readslide_destroy_cb( VipsImage *image, ReadSlide *rslide )
{
	VIPS_FREEF( openslide_close, rslide->osr );
	VIPS_FREE( rslide->associated );
	VIPS_FREE( rslide->filename );
	VIPS_FREE( rslide );
}

static int
check_associated_image( openslide_t *osr, const char *name )
{
	const char * const *associated;

	for( associated = openslide_get_associated_image_names( osr );
		*associated != NULL; associated++ )
		if( strcmp( *associated, name ) == 0 )
			return( 0 );

	vips_error( "openslide2vips", 
		"%s", _( "invalid associated image name" ) );

	return( -1 );
}

static gboolean
get_bounds( openslide_t *osr, VipsRect *rect )
{
	static const char *openslide_names[] = {
		"openslide.bounds-x", 
		"openslide.bounds-y", 
		"openslide.bounds-width", 
		"openslide.bounds-height"
	};
	static int vips_offsets[] = {
		G_STRUCT_OFFSET( VipsRect, left ),
		G_STRUCT_OFFSET( VipsRect, top ),
		G_STRUCT_OFFSET( VipsRect, width ),
		G_STRUCT_OFFSET( VipsRect, height )
	};

	const char *value;
	int i;

	for( i = 0; i < 4; i++ ) { 
		if( !(value = openslide_get_property_value( osr, 
			openslide_names[i] )) ) 
			return( FALSE );
		G_STRUCT_MEMBER( int, rect, vips_offsets[i] ) = 
			atoi( value );
	}

	return( TRUE );
}

static ReadSlide *
readslide_new( const char *filename, VipsImage *out, 
	int level, gboolean autocrop, 
	const char *associated, gboolean attach_associated )
{
	ReadSlide *rslide;

	if( level && 
		associated ) {
		vips_error( "openslide2vips",
			"%s", _( "specify only one of level and "
			"associated image" ) );
		return( NULL );
	}

	if( attach_associated && 
		associated ) {
		vips_error( "openslide2vips",
			"%s", _( "specify only one of attach_assicated and "
			"associated image" ) );
		return( NULL );
	}

	rslide = VIPS_NEW( NULL, ReadSlide );
	memset( rslide, 0, sizeof( *rslide ) );
	g_signal_connect( out, "close", G_CALLBACK( readslide_destroy_cb ),
		rslide );

	rslide->filename = g_strdup( filename );
	rslide->out = out;
	rslide->level = level;
	rslide->autocrop = autocrop;
	rslide->associated = g_strdup( associated );
	rslide->attach_associated = attach_associated;

	/* Non-crazy defaults, override in _parse() if we can.
	 */
	rslide->tile_width = 256;
	rslide->tile_height = 256;

	return( rslide );
}

/* Convert from ARGB to RGBA and undo premultiplication. 
 *
 * We throw away transparency. Formats like Mirax use transparent + bg
 * colour for areas with no useful pixels. But if we output
 * transparent pixels and then convert to RGB for jpeg write later, we
 * would have to pass the bg colour down the pipe somehow. The
 * structure of dzsave makes this tricky.
 *
 * We could output plain RGB instead, but that would break
 * compatibility with older vipses.
 */
static void
argb2rgba( uint32_t * restrict buf, int n, uint32_t bg )
{
	const uint32_t pbg = GUINT32_TO_BE( (bg << 8) | 255 );

	int i;

	for( i = 0; i < n; i++ ) {
		uint32_t * restrict p = buf + i;
		uint32_t x = *p;
		uint8_t a = x >> 24;
		VipsPel * restrict out = (VipsPel *) p;

		if( a == 255 ) 
			*p = GUINT32_TO_BE( (x << 8) | 255 );
		else if( a == 0 ) 
			/* Use background color.
			 */
			*p = pbg;
		else {
			/* Undo premultiplication.
			 */
			out[0] = 255 * ((x >> 16) & 255) / a;
			out[1] = 255 * ((x >> 8) & 255) / a;
			out[2] = 255 * (x & 255) / a;
			out[3] = 255;
		}
	}
}

static int
readslide_attach_associated( ReadSlide *rslide, VipsImage *image )
{
	const char * const *associated_name;

	for( associated_name = 
		openslide_get_associated_image_names( rslide->osr );
		*associated_name != NULL; associated_name++ ) {
		int64_t w, h;
		VipsImage *associated;
		uint32_t *p;
		const char *error;
		char buf[256];

		associated = vips_image_new_memory();
		openslide_get_associated_image_dimensions( rslide->osr,
			*associated_name, &w, &h );
		vips_image_init_fields( associated, w, h, 4, VIPS_FORMAT_UCHAR,
			VIPS_CODING_NONE, VIPS_INTERPRETATION_sRGB, 1.0, 1.0 );
		vips_image_pipelinev( associated, 
			VIPS_DEMAND_STYLE_THINSTRIP, NULL );

		if( vips_image_write_prepare( associated ) ) {
			g_object_unref( associated );
			return( -1 );
		}
		p = (uint32_t *) VIPS_IMAGE_ADDR( associated, 0, 0 );
		openslide_read_associated_image( rslide->osr, 
			*associated_name, p );
		error = openslide_get_error( rslide->osr );
		if( error ) {
			vips_error( "openslide2vips",
				_( "reading associated image: %s" ), error );
			g_object_unref( associated );
			return( -1 );
		}
		argb2rgba( p, w * h, rslide->bg );

		vips_snprintf( buf, 256, 
			"openslide.associated.%s", *associated_name );
		vips_image_set_image( image, buf, associated );
		g_object_unref( associated );
	}

	return( 0 );
}

/* Read out a resolution field, converting to pixels per mm.
 */
static double
readslice_parse_res( ReadSlide *rslide, const char *name )
{
	const char *value = openslide_get_property_value( rslide->osr, name );
	double mpp = g_ascii_strtod( value, NULL );

	return( mpp == 0 ? 1.0 : 1000.0 / mpp );
}

static int
readslide_parse( ReadSlide *rslide, VipsImage *image )
{
	int64_t w, h;
	const char *error;
	const char *background;
	const char * const *properties;
	char *associated_names;
	double xres;
	double yres;

	rslide->osr = openslide_open( rslide->filename );
	if( rslide->osr == NULL ) {
		vips_error( "openslide2vips", 
			"%s", _( "unsupported slide format" ) );
		return( -1 );
	}

	error = openslide_get_error( rslide->osr );
	if( error ) {
		vips_error( "openslide2vips",
			_( "opening slide: %s" ), error );
		return( -1 );
	}

	if( rslide->level < 0 || 
		rslide->level >= openslide_get_level_count( rslide->osr ) ) {
		vips_error( "openslide2vips",
			"%s", _( "invalid slide level" ) );
		return( -1 );
	}

	if( rslide->associated &&
		check_associated_image( rslide->osr, rslide->associated ) )
		return( -1 );

	if( rslide->associated ) {
		openslide_get_associated_image_dimensions( rslide->osr,
			rslide->associated, &w, &h );
		vips_image_set_string( image, "slide-associated-image",
			rslide->associated );
		vips_image_pipelinev( image, VIPS_DEMAND_STYLE_THINSTRIP, NULL );
	} 
	else {
		char buf[256];
		const char *value;

		openslide_get_level_dimensions( rslide->osr,
			rslide->level, &w, &h );
		rslide->downsample = openslide_get_level_downsample(
			rslide->osr, rslide->level );
		vips_image_set_int( image, "slide-level", rslide->level );
		vips_image_pipelinev( image, VIPS_DEMAND_STYLE_SMALLTILE, NULL );

		/* Try to get tile width/height. An undocumented, experimental
		 * feature.
		 */
		vips_snprintf( buf, 256, 
			"openslide.level[%d].tile-width", rslide->level );
		if( (value = openslide_get_property_value( rslide->osr, buf )) )
			rslide->tile_width = atoi( value );
		vips_snprintf( buf, 256, 
			"openslide.level[%d].tile-height", rslide->level );
		if( (value = openslide_get_property_value( rslide->osr, buf )) )
			rslide->tile_height = atoi( value );
		if( value )
			VIPS_DEBUG_MSG( "readslide_new: found tile-size\n" );

		/* Some images have a bounds in the header. Crop to 
		 * that if autocrop is set. 
		 */
		if( rslide->autocrop ) 
			if( !get_bounds( rslide->osr, &rslide->bounds ) )
				rslide->autocrop = FALSE; 
		if( rslide->autocrop ) {
			VipsRect whole;

			rslide->bounds.left /= rslide->downsample;
			rslide->bounds.top /= rslide->downsample;
			rslide->bounds.width /= rslide->downsample;
			rslide->bounds.height /= rslide->downsample;

			/* Clip against image size.
			 */
			whole.left = 0;
			whole.top = 0;
			whole.width = w;
			whole.height = h;
			vips_rect_intersectrect( &rslide->bounds, &whole, 
				&rslide->bounds );

			/* If we've clipped to nothing, ignore bounds.
			 */
			if( vips_rect_isempty( &rslide->bounds ) )
				rslide->autocrop = FALSE;
		}
		if( rslide->autocrop ) {
			w = rslide->bounds.width;
			h = rslide->bounds.height;
		}

		/* Attach all associated images.
		 */
		if( rslide->attach_associated &&
			readslide_attach_associated( rslide, image ) )
			return( -1 ); 
	}

	rslide->bg = 0xffffff;
	if( (background = openslide_get_property_value( rslide->osr,
		OPENSLIDE_PROPERTY_NAME_BACKGROUND_COLOR )) )
		rslide->bg = strtoul( background, NULL, 16 );

	if( w <= 0 || 
		h <= 0 || 
		rslide->downsample < 0 ) {
		vips_error( "openslide2vips", _( "getting dimensions: %s" ),
			openslide_get_error( rslide->osr ) );
		return( -1 );
	}
	if( w > INT_MAX || 
		h > INT_MAX ) {
		vips_error( "openslide2vips",
			"%s", _( "image dimensions overflow int" ) );
		return( -1 );
	}

	if( !rslide->autocrop ) {
		rslide->bounds.left = 0;
		rslide->bounds.top = 0;
		rslide->bounds.width = w;
		rslide->bounds.height = h;
	}

	/* Try to get resolution from openslide properties.
	 */
	xres = 1.0;
	yres = 1.0;

	for( properties = openslide_get_property_names( rslide->osr );
		*properties != NULL; properties++ ) {
		const char *name = *properties;
		const char *value = 
			openslide_get_property_value( rslide->osr, name );

		/* Can be NULL for some openslides with some images.
		 */
		if( value ) { 
			vips_image_set_string( image, name, value ); 

			if( strcmp( *properties, "openslide.mpp-x" ) == 0 ) 
				xres = readslice_parse_res( rslide, name );
			if( strcmp( *properties, "openslide.mpp-y" ) == 0 ) 
				yres = readslice_parse_res( rslide, name );
		}
	}

	associated_names = g_strjoinv( ", ", (char **)
		openslide_get_associated_image_names( rslide->osr ) );
	vips_image_set_string( image, 
		"slide-associated-images", associated_names );
	VIPS_FREE( associated_names );

	vips_image_init_fields( image, w, h, 4, VIPS_FORMAT_UCHAR,
		VIPS_CODING_NONE, VIPS_INTERPRETATION_sRGB, xres, yres );

	return( 0 );
}

int
vips__openslide_read_header( const char *filename, VipsImage *out, 
	int level, gboolean autocrop, 
	char *associated, gboolean attach_associated )
{
	ReadSlide *rslide;

	if( !(rslide = readslide_new( filename, 
		out, level, autocrop, associated, attach_associated )) ||
		readslide_parse( rslide, out ) )
		return( -1 );

	return( 0 );
}

static int
vips__openslide_generate( VipsRegion *out, 
	void *_seq, void *_rslide, void *unused, gboolean *stop )
{
	ReadSlide *rslide = _rslide;
	uint32_t bg = rslide->bg;
	VipsRect *r = &out->valid;
	int n = r->width * r->height;
	uint32_t *buf = (uint32_t *) VIPS_REGION_ADDR( out, r->left, r->top );

	const char *error;

	VIPS_DEBUG_MSG( "vips__openslide_generate: %dx%d @ %dx%d\n",
		r->width, r->height, r->left, r->top );

	/* We're inside a cache, so requests should always be
	 * tile_width by tile_height pixels and on a tile boundary.
	 */
	g_assert( (r->left % rslide->tile_width) == 0 );
	g_assert( (r->top % rslide->tile_height) == 0 );
	g_assert( r->width <= rslide->tile_width );
	g_assert( r->height <= rslide->tile_height );

	/* The memory on the region should be contiguous for our ARGB->RGBA
	 * loop below.
	 */
	g_assert( VIPS_REGION_LSKIP( out ) == r->width * 4 );

	openslide_read_region( rslide->osr, 
		buf,
		(r->left + rslide->bounds.left) * rslide->downsample, 
		(r->top + rslide->bounds.top) * rslide->downsample, 
		rslide->level,
		r->width, r->height ); 

	/* openslide errors are terminal. To support
	 * @fail we'd have to close the openslide_t and reopen, perhaps 
	 * somehow marking this tile as unreadable.
	 *
	 * See
	 * https://github.com/libvips/libvips/commit/bb0a6643f94e69294e36d2b253f9bdd60c8c40ed#commitcomment-19838911
	 */
	error = openslide_get_error( rslide->osr );
	if( error ) {
		vips_error( "openslide2vips", 
			_( "reading region: %s" ), error );
		return( -1 );
	}

	/* Since we are inside a cache, we know buf must be continuous.
	 */
	argb2rgba( buf, n, bg );

	return( 0 );
}

int
vips__openslide_read( const char *filename, VipsImage *out, 
	int level, gboolean autocrop, gboolean attach_associated )
{
	ReadSlide *rslide;
	VipsImage *raw;
	VipsImage *t;

	VIPS_DEBUG_MSG( "vips__openslide_read: %s %d\n", 
		filename, level );

	if( !(rslide = readslide_new( filename, out, level, autocrop, 
		NULL, attach_associated )) )
		return( -1 );

	raw = vips_image_new();
	vips_object_local( out, raw );

	if( readslide_parse( rslide, raw ) ||
		vips_image_generate( raw, 
			NULL, vips__openslide_generate, NULL, rslide, NULL ) )
		return( -1 );

	/* Copy to out, adding a cache. Enough tiles for two complete rows, 
	 * plus 50%. We need at least two rows, or we'll constantly reload
	 * tiles if they cross a tile boundary.
	 */
	if( vips_tilecache( raw, &t, 
		"tile_width", rslide->tile_width, 
		"tile_height", rslide->tile_height,
		"max_tiles", 
			(int) (2.5 * (1 + raw->Xsize / rslide->tile_width)),
		"threaded", TRUE,
		NULL ) ) 
		return( -1 );
	if( vips_image_write( t, out ) ) {
		g_object_unref( t );
		return( -1 );
	}
	g_object_unref( t );

	return( 0 );
}

int
vips__openslide_read_associated( const char *filename, VipsImage *out, 
	const char *associated )
{
	ReadSlide *rslide;
	VipsImage *raw;
	uint32_t *buf;
	const char *error;

	VIPS_DEBUG_MSG( "vips__openslide_read_associated: %s %s\n", 
		filename, associated );

	if( !(rslide = readslide_new( filename, out, 0, FALSE, 
		associated, FALSE )) )
		return( -1 );

	/* Memory buffer. Get associated directly to this, then copy to out.
	 */
	raw = vips_image_new_memory();
	vips_object_local( out, raw );

	if( readslide_parse( rslide, raw ) ||
		vips_image_write_prepare( raw ) )
		return( -1 );

	buf = (uint32_t *) VIPS_IMAGE_ADDR( raw, 0, 0 );
	openslide_read_associated_image( rslide->osr, rslide->associated, buf );
	error = openslide_get_error( rslide->osr );
	if( error ) {
		vips_error( "openslide2vips",
			_( "reading associated image: %s" ), error );
		return( -1 );
	}
	argb2rgba( buf, raw->Xsize * raw->Ysize, rslide->bg );

	if( vips_image_write( raw, out ) ) 
		return( -1 );

	return( 0 );
}

#endif /*HAVE_OPENSLIDE*/