File: hscore.h

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wise 2.4.1-21
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#ifndef DYNAMITEhscoreHEADERFILE
#define DYNAMITEhscoreHEADERFILE
#ifdef _cplusplus
extern "C" {
#endif
#include "wisebase.h"
#include "histogram.h"

#define HscoreLISTLENGTH 256
#define DATAENTRYSTDPOINTS 8

#define DATASCORESTORAGE_LENGTH 1024

typedef long BytePosition;
/* Object DataEntry
 *
 * Descrip: A lightweight structure to represent the information
 *        a db search algorithm will want to store and *nothing*
 *        more about a single entry
 *
 *        This object will be stored twice (once for the target
 *        and once for the query) for each comparison: they probably
 *        will be on different databases and different objects. 
 *
 *        The data field is just a number (8 at the moment) of int's available
 *        for databases to store useful information (eg, length) of the 
 *        object.
 *
 *        A number of extra fields are provided for convience sake for indexers, 
 *        including byte_position and filename.
 *
 *
 */
struct Wise2_DataEntry {  
    int dynamite_hard_link;  
#ifdef PTHREAD   
    pthread_mutex_t dynamite_mutex;  
#endif   
    char * name;    /*  name of the entry */ 
    int data[DATAENTRYSTDPOINTS];   /*  space for algorithms to use  */ 
    boolean is_reversed;    /*  for sequences. handy */ 
    BytePosition byte_position; /*  useful for indexers - hopefully long enough! */ 
    char * filename;    /*  useful for indexers etc. */ 
    } ;  
/* DataEntry defined */ 
#ifndef DYNAMITE_DEFINED_DataEntry
typedef struct Wise2_DataEntry Wise2_DataEntry;
#define DataEntry Wise2_DataEntry
#define DYNAMITE_DEFINED_DataEntry
#endif


/* Object DataScore
 *
 * Descrip: The basic one entry vs one entry structure. Each
 *        of the DataEntry datastructures actually store the 
 *        information about the indexing etc.
 *
 *
 */
struct Wise2_DataScore {  
    int dynamite_hard_link;  
#ifdef PTHREAD   
    pthread_mutex_t dynamite_mutex;  
#endif   
    DataEntry * query;   
    DataEntry * target;  
    int score;   
    double evalue;   
    int is_stored;   
    } ;  
/* DataScore defined */ 
#ifndef DYNAMITE_DEFINED_DataScore
typedef struct Wise2_DataScore Wise2_DataScore;
#define DataScore Wise2_DataScore
#define DYNAMITE_DEFINED_DataScore
#endif


/* Object DataScoreStorage
 *
 * Descrip: This object was needed because for very large searches
 *        the memory usage of allocation DataScore and DataEntry's
 *        on the heap was becoming prohibative.
 *
 *        This datastructure holds pre-allocated DataScore and DataEntry
 *        objects read for use. A complicated constructor/deconstructor
 *        pair for DataScore objects ensures that these can be used
 *        cleanly.
 *
 *
 */
struct Wise2_DataScoreStorage {  
    int dynamite_hard_link;  
#ifdef PTHREAD   
    pthread_mutex_t dynamite_mutex;  
#endif   
    DataScore score_array[DATASCORESTORAGE_LENGTH];  
    DataEntry query_array[DATASCORESTORAGE_LENGTH];  
    DataEntry target_array[DATASCORESTORAGE_LENGTH];     
    int curr_pos;    
    } ;  
/* DataScoreStorage defined */ 
#ifndef DYNAMITE_DEFINED_DataScoreStorage
typedef struct Wise2_DataScoreStorage Wise2_DataScoreStorage;
#define DataScoreStorage Wise2_DataScoreStorage
#define DYNAMITE_DEFINED_DataScoreStorage
#endif


/* Object Hscore
 *
 * Descrip: Holds the information about a db search.
 *        Meant to be very lightweight
 *
 *        The histogram is carried for on-the-fly histogram storage outside
 *        of the database. The idea is that the function should_store will
 *        tell whether the datascore structure should be stored (if it is
 *        NULL, it is always stored). The score_to_his function maps the
 *        score in datascore to the float in Histogram, allowing the scoring
 *        system of the search method to be on a different basis to the 
 *        scoring system of the histogram. For most times, this is going to
 *        be Score2Bits
 *
 *        To prevent too much dependency, the 'standard' way of making a 
 *        histogram that has a bits cut off level is done using functions
 *        in the dynlibcross module (cross code), as it needs both Hscore and
 *        Probability. You should read dynlibcross module for the constructors
 *        for Hscore
 *
 *
 */
struct Wise2_Hscore {  
    int dynamite_hard_link;  
#ifdef PTHREAD   
    pthread_mutex_t dynamite_mutex;  
#endif   
    DataScore ** ds;     
    int len;/* len for above ds  */ 
    int maxlen; /* maxlen for above ds */ 
    DataScoreStorage ** store;   
    int st_len; /* len for above store  */ 
    int st_maxlen;  /* maxlen for above store */ 
    Histogram * his;     
    double score_level; /*  passed into should_store function */ 
    boolean (*should_store)(int given_score,double internal_score_level);    
    float (*score_to_his)(int given_score);  
    int report_level;   /*  number of sequences to report on */ 
    long total; /*  total number of scores (duplicated info in histogram)  */ 
    } ;  
/* Hscore defined */ 
#ifndef DYNAMITE_DEFINED_Hscore
typedef struct Wise2_Hscore Wise2_Hscore;
#define Hscore Wise2_Hscore
#define DYNAMITE_DEFINED_Hscore
#endif




    /***************************************************/
    /* Callable functions                              */
    /* These are the functions you are expected to use */
    /***************************************************/



/* Function:  std_score_Hscore(cut_off,report_stagger)
 *
 * Descrip:    This gives you a standard Hscore
 *             module with a cutoff in score
 *
 *
 * Arg:               cut_off [UNKN ] Undocumented argument [int]
 * Arg:        report_stagger [UNKN ] Undocumented argument [int]
 *
 * Return [UNKN ]  Undocumented return value [Hscore *]
 *
 */
Hscore * Wise2_std_score_Hscore(int cut_off,int report_stagger);
#define std_score_Hscore Wise2_std_score_Hscore


/* Function:  should_store_Hscore(hs,score)
 *
 * Descrip:    Tells whether this score should be stored
 *             or not. Also updates Histogram if needed
 *
 *
 * Arg:           hs [UNKN ] Undocumented argument [Hscore *]
 * Arg:        score [UNKN ] Undocumented argument [int]
 *
 * Return [UNKN ]  Undocumented return value [boolean]
 *
 */
boolean Wise2_should_store_Hscore(Hscore * hs,int score);
#define should_store_Hscore Wise2_should_store_Hscore


/* Function:  length_datascore_Hscore(obj)
 *
 * Descrip:    Returns the number of datascores in the hscore
 *             structure
 *
 *
 * Arg:        obj [READ ] Hscore object [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [int]
 *
 */
int Wise2_length_datascore_Hscore(Hscore * obj);
#define length_datascore_Hscore Wise2_length_datascore_Hscore


/* Function:  get_datascore_Hscore(hs,i)
 *
 * Descrip:    Returns the specific datascore held at this
 *             position.
 *
 *             This requires a considerable amount of memory
 *             duplication, so please dont process all your
 *             results by looping through this.
 *
 *
 * Arg:        hs [READ ] Hscore object [Hscore *]
 * Arg:         i [UNKN ] position to be read [int]
 *
 * Return [OWNER]  New datascore object [DataScore *]
 *
 */
DataScore * Wise2_get_datascore_Hscore(Hscore * hs,int i);
#define get_datascore_Hscore Wise2_get_datascore_Hscore


/* Function:  get_score_Hscore(hs,i)
 *
 * Descrip: No Description
 *
 * Arg:        hs [READ ] Hscore object [Hscore *]
 * Arg:         i [UNKN ] position to be read [int]
 *
 * Return [UNKN ]  score  [int]
 *
 */
int Wise2_get_score_Hscore(Hscore * hs,int i);
#define get_score_Hscore Wise2_get_score_Hscore


/* Function:  get_evalue_Hscore(hs,i)
 *
 * Descrip:    Returns the evalue of the specific datascore held at this position.
 *
 *
 *
 * Arg:        hs [READ ] Hscore object [Hscore *]
 * Arg:         i [UNKN ] position to be read [int]
 *
 * Return [UNKN ]  evalue  [double]
 *
 */
double Wise2_get_evalue_Hscore(Hscore * hs,int i);
#define get_evalue_Hscore Wise2_get_evalue_Hscore


/* Function:  fit_Hscore_to_EVD(hs,guess_of_outliers)
 *
 * Descrip:    If a histogram is present, tries to fit the histogram and
 *             then gives evalues to all the scores in the Hscore model
 *
 *
 * Arg:                       hs [UNKN ] Undocumented argument [Hscore *]
 * Arg:        guess_of_outliers [UNKN ] Undocumented argument [float]
 *
 * Return [UNKN ]  Undocumented return value [boolean]
 *
 */
boolean Wise2_fit_Hscore_to_EVD(Hscore * hs,float guess_of_outliers);
#define fit_Hscore_to_EVD Wise2_fit_Hscore_to_EVD


/* Function:  minimum_score_Hscore(hs)
 *
 * Descrip:    gets the minimum score from Hscore
 *
 *
 * Arg:        hs [UNKN ] Undocumented argument [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [int]
 *
 */
int Wise2_minimum_score_Hscore(Hscore * hs);
#define minimum_score_Hscore Wise2_minimum_score_Hscore


/* Function:  maximum_score_Hscore(hs)
 *
 * Descrip:    gets the maximum score from Hscore
 *
 *
 * Arg:        hs [UNKN ] Undocumented argument [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [int]
 *
 */
int Wise2_maximum_score_Hscore(Hscore * hs);
#define maximum_score_Hscore Wise2_maximum_score_Hscore


/* Function:  basic_show_Hscore(hs,ofp)
 *
 * Descrip:    The most baby-talk showing of Hscore
 *
 *
 * Arg:         hs [UNKN ] Undocumented argument [Hscore *]
 * Arg:        ofp [UNKN ] Undocumented argument [FILE *]
 *
 */
void Wise2_basic_show_Hscore(Hscore * hs,FILE * ofp);
#define basic_show_Hscore Wise2_basic_show_Hscore


/* Function:  sort_Hscore_by_score(hs)
 *
 * Descrip:    As it says, sorts the high score by its score
 *
 *
 * Arg:        hs [UNKN ] Hscore to be sorted [Hscore *]
 *
 */
void Wise2_sort_Hscore_by_score(Hscore * hs);
#define sort_Hscore_by_score Wise2_sort_Hscore_by_score


/* Function:  free_DataScore(obj)
 *
 * Descrip:    Correctly handles destruction of a datascore
 *
 *
 * Arg:        obj [UNKN ] Undocumented argument [DataScore *]
 *
 * Return [UNKN ]  Undocumented return value [DataScore *]
 *
 */
DataScore * Wise2_free_DataScore(DataScore * obj);
#define free_DataScore Wise2_free_DataScore


/* Function:  free_DataScoreStorage(obj)
 *
 * Descrip:    Correctly handles destruction of DataScoreStorage, by
 *             freeing members in data storage
 *
 *
 * Arg:        obj [UNKN ] Undocumented argument [DataScoreStorage *]
 *
 * Return [UNKN ]  Undocumented return value [DataScoreStorage *]
 *
 */
DataScoreStorage * Wise2_free_DataScoreStorage(DataScoreStorage * obj);
#define free_DataScoreStorage Wise2_free_DataScoreStorage


/* Function:  new_DataScoreStorage(void)
 *
 * Descrip:    Makes a new DataScoreStorage with all the pointers connected correctly
 *
 *
 *
 * Return [UNKN ]  Undocumented return value [DataScoreStorage *]
 *
 */
DataScoreStorage * Wise2_new_DataScoreStorage(void);
#define new_DataScoreStorage Wise2_new_DataScoreStorage


/* Function:  hard_link_DataEntry(obj)
 *
 * Descrip:    Bumps up the reference count of the object
 *             Meaning that multiple pointers can 'own' it
 *
 *
 * Arg:        obj [UNKN ] Object to be hard linked [DataEntry *]
 *
 * Return [UNKN ]  Undocumented return value [DataEntry *]
 *
 */
DataEntry * Wise2_hard_link_DataEntry(DataEntry * obj);
#define hard_link_DataEntry Wise2_hard_link_DataEntry


/* Function:  DataEntry_alloc(void)
 *
 * Descrip:    Allocates structure: assigns defaults if given 
 *
 *
 *
 * Return [UNKN ]  Undocumented return value [DataEntry *]
 *
 */
DataEntry * Wise2_DataEntry_alloc(void);
#define DataEntry_alloc Wise2_DataEntry_alloc


/* Function:  free_DataEntry(obj)
 *
 * Descrip:    Free Function: removes the memory held by obj
 *             Will chain up to owned members and clear all lists
 *
 *
 * Arg:        obj [UNKN ] Object that is free'd [DataEntry *]
 *
 * Return [UNKN ]  Undocumented return value [DataEntry *]
 *
 */
DataEntry * Wise2_free_DataEntry(DataEntry * obj);
#define free_DataEntry Wise2_free_DataEntry


/* Function:  hard_link_DataScore(obj)
 *
 * Descrip:    Bumps up the reference count of the object
 *             Meaning that multiple pointers can 'own' it
 *
 *
 * Arg:        obj [UNKN ] Object to be hard linked [DataScore *]
 *
 * Return [UNKN ]  Undocumented return value [DataScore *]
 *
 */
DataScore * Wise2_hard_link_DataScore(DataScore * obj);
#define hard_link_DataScore Wise2_hard_link_DataScore


/* Function:  DataScore_alloc(void)
 *
 * Descrip:    Allocates structure: assigns defaults if given 
 *
 *
 *
 * Return [UNKN ]  Undocumented return value [DataScore *]
 *
 */
DataScore * Wise2_DataScore_alloc(void);
#define DataScore_alloc Wise2_DataScore_alloc


/* Function:  hard_link_DataScoreStorage(obj)
 *
 * Descrip:    Bumps up the reference count of the object
 *             Meaning that multiple pointers can 'own' it
 *
 *
 * Arg:        obj [UNKN ] Object to be hard linked [DataScoreStorage *]
 *
 * Return [UNKN ]  Undocumented return value [DataScoreStorage *]
 *
 */
DataScoreStorage * Wise2_hard_link_DataScoreStorage(DataScoreStorage * obj);
#define hard_link_DataScoreStorage Wise2_hard_link_DataScoreStorage


/* Function:  DataScoreStorage_alloc(void)
 *
 * Descrip:    Allocates structure: assigns defaults if given 
 *
 *
 *
 * Return [UNKN ]  Undocumented return value [DataScoreStorage *]
 *
 */
DataScoreStorage * Wise2_DataScoreStorage_alloc(void);
#define DataScoreStorage_alloc Wise2_DataScoreStorage_alloc


/* Function:  add_Hscore(obj,add)
 *
 * Descrip:    Adds another object to the list. It will expand the list if necessary
 *
 *
 * Arg:        obj [UNKN ] Object which contains the list [Hscore *]
 * Arg:        add [OWNER] Object to add to the list [DataScore *]
 *
 * Return [UNKN ]  Undocumented return value [boolean]
 *
 */
boolean Wise2_add_Hscore(Hscore * obj,DataScore * add);
#define add_Hscore Wise2_add_Hscore


/* Function:  flush_Hscore(obj)
 *
 * Descrip:    Frees the list elements, sets length to 0
 *             If you want to save some elements, use hard_link_xxx
 *             to protect them from being actually destroyed in the free
 *
 *
 * Arg:        obj [UNKN ] Object which contains the list  [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [int]
 *
 */
int Wise2_flush_Hscore(Hscore * obj);
#define flush_Hscore Wise2_flush_Hscore


/* Function:  add_st_Hscore(obj,add)
 *
 * Descrip:    Adds another object to the list. It will expand the list if necessary
 *
 *
 * Arg:        obj [UNKN ] Object which contains the list [Hscore *]
 * Arg:        add [OWNER] Object to add to the list [DataScoreStorage *]
 *
 * Return [UNKN ]  Undocumented return value [boolean]
 *
 */
boolean Wise2_add_st_Hscore(Hscore * obj,DataScoreStorage * add);
#define add_st_Hscore Wise2_add_st_Hscore


/* Function:  flush_st_Hscore(obj)
 *
 * Descrip:    Frees the list elements, sets length to 0
 *             If you want to save some elements, use hard_link_xxx
 *             to protect them from being actually destroyed in the free
 *
 *
 * Arg:        obj [UNKN ] Object which contains the list  [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [int]
 *
 */
int Wise2_flush_st_Hscore(Hscore * obj);
#define flush_st_Hscore Wise2_flush_st_Hscore


/* Function:  Hscore_alloc_std(void)
 *
 * Descrip:    Equivalent to Hscore_alloc_len(HscoreLISTLENGTH)
 *
 *
 *
 * Return [UNKN ]  Undocumented return value [Hscore *]
 *
 */
Hscore * Wise2_Hscore_alloc_std(void);
#define Hscore_alloc_std Wise2_Hscore_alloc_std


/* Function:  Hscore_alloc_len(len)
 *
 * Descrip:    Allocates len length to all lists
 *
 *
 * Arg:        len [UNKN ] Length of lists to allocate [int]
 *
 * Return [UNKN ]  Undocumented return value [Hscore *]
 *
 */
Hscore * Wise2_Hscore_alloc_len(int len);
#define Hscore_alloc_len Wise2_Hscore_alloc_len


/* Function:  hard_link_Hscore(obj)
 *
 * Descrip:    Bumps up the reference count of the object
 *             Meaning that multiple pointers can 'own' it
 *
 *
 * Arg:        obj [UNKN ] Object to be hard linked [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [Hscore *]
 *
 */
Hscore * Wise2_hard_link_Hscore(Hscore * obj);
#define hard_link_Hscore Wise2_hard_link_Hscore


/* Function:  Hscore_alloc(void)
 *
 * Descrip:    Allocates structure: assigns defaults if given 
 *
 *
 *
 * Return [UNKN ]  Undocumented return value [Hscore *]
 *
 */
Hscore * Wise2_Hscore_alloc(void);
#define Hscore_alloc Wise2_Hscore_alloc


/* Function:  free_Hscore(obj)
 *
 * Descrip:    Free Function: removes the memory held by obj
 *             Will chain up to owned members and clear all lists
 *
 *
 * Arg:        obj [UNKN ] Object that is free'd [Hscore *]
 *
 * Return [UNKN ]  Undocumented return value [Hscore *]
 *
 */
Hscore * Wise2_free_Hscore(Hscore * obj);
#define free_Hscore Wise2_free_Hscore


  /* Unplaced functions */
  /* There has been no indication of the use of these functions */


    /***************************************************/
    /* Internal functions                              */
    /* you are not expected to have to call these      */
    /***************************************************/
DataEntry * Wise2_access_query_DataScore(DataScore * obj);
#define access_query_DataScore Wise2_access_query_DataScore
boolean Wise2_replace_target_DataScore(DataScore * obj,DataEntry * target);
#define replace_target_DataScore Wise2_replace_target_DataScore
DataEntry * Wise2_access_target_DataScore(DataScore * obj);
#define access_target_DataScore Wise2_access_target_DataScore
boolean Wise2_replace_is_reversed_DataEntry(DataEntry * obj,boolean is_reversed);
#define replace_is_reversed_DataEntry Wise2_replace_is_reversed_DataEntry
boolean Wise2_replace_score_DataScore(DataScore * obj,int score);
#define replace_score_DataScore Wise2_replace_score_DataScore
boolean Wise2_access_is_reversed_DataEntry(DataEntry * obj);
#define access_is_reversed_DataEntry Wise2_access_is_reversed_DataEntry
int Wise2_access_score_DataScore(DataScore * obj);
#define access_score_DataScore Wise2_access_score_DataScore
boolean Wise2_replace_query_DataScore(DataScore * obj,DataEntry * query);
#define replace_query_DataScore Wise2_replace_query_DataScore
boolean Wise2_replace_evalue_DataScore(DataScore * obj,double evalue);
#define replace_evalue_DataScore Wise2_replace_evalue_DataScore
char * Wise2_access_name_DataEntry(DataEntry * obj);
#define access_name_DataEntry Wise2_access_name_DataEntry
boolean Wise2_replace_name_DataEntry(DataEntry * obj,char * name);
#define replace_name_DataEntry Wise2_replace_name_DataEntry
double Wise2_access_evalue_DataScore(DataScore * obj);
#define access_evalue_DataScore Wise2_access_evalue_DataScore
boolean Wise2_raw_should_store_Hscore(int score,double cutoff);
#define raw_should_store_Hscore Wise2_raw_should_store_Hscore
float Wise2_raw_score_to_his(int score);
#define raw_score_to_his Wise2_raw_score_to_his
void Wise2_copy_DataEntry(DataEntry * from,DataEntry * to);
#define copy_DataEntry Wise2_copy_DataEntry
int Wise2_compare_DataScore_by_score(DataScore * one,DataScore * two);
#define compare_DataScore_by_score Wise2_compare_DataScore_by_score
DataScore * Wise2_new_DataScore(void);
#define new_DataScore Wise2_new_DataScore
DataScore * Wise2_new_DataScore_from_storage(Hscore * hs);
#define new_DataScore_from_storage Wise2_new_DataScore_from_storage
void Wise2_swap_Hscore(DataScore ** list,int i,int j) ;
#define swap_Hscore Wise2_swap_Hscore
void Wise2_qsort_Hscore(DataScore ** list,int left,int right,int (*comp)(DataScore * ,DataScore * ));
#define qsort_Hscore Wise2_qsort_Hscore
void Wise2_sort_Hscore(Hscore * obj,int (*comp)(DataScore *, DataScore *));
#define sort_Hscore Wise2_sort_Hscore
boolean Wise2_expand_Hscore(Hscore * obj,int len);
#define expand_Hscore Wise2_expand_Hscore
void Wise2_swap_st_Hscore(DataScoreStorage ** list,int i,int j) ;
#define swap_st_Hscore Wise2_swap_st_Hscore
void Wise2_qsort_st_Hscore(DataScoreStorage ** list,int left,int right,int (*comp)(DataScoreStorage * ,DataScoreStorage * ));
#define qsort_st_Hscore Wise2_qsort_st_Hscore
void Wise2_sort_st_Hscore(Hscore * obj,int (*comp)(DataScoreStorage *, DataScoreStorage *));
#define sort_st_Hscore Wise2_sort_st_Hscore
boolean Wise2_expand_st_Hscore(Hscore * obj,int len);
#define expand_st_Hscore Wise2_expand_st_Hscore

#ifdef _cplusplus
}
#endif

#endif