1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
|
test_KEGG
Testing Bio.KEGG.Enzyme on enzyme.sample
ENTRY EC 1.1.1.1
NAME Alcohol dehydrogenase
Aldehyde reductase
CLASS Oxidoreductases
Acting on the CH-OH group of donors
With NAD+ or NADP+ as acceptor
SYSNAME Alcohol:NAD+ oxidoreductase
REACTION Alcohol + NAD+ = Aldehyde or Ketone + NADH
SUBSTRATE NAD+
Primary alcohol
Secondary alcohol
Cyclic secondary alcohol
Hemiacetal
PRODUCT Aldehyde
Ketone
NADH
COFACTOR Zinc
COMMENT A zinc protein. Acts on primary or secondary alcohols or
hemiacetals; the animal, but not the yeast, enzyme acts also on
cyclic secondary alcohols
The insect enzyme is a member of the nonmetallo-short-chain
alcohol dehydrogenase (ADH) family (Proc.Natl.Acad.Sci.USA(1991)
88, 10064-10068).
PATHWAY PATH: MAP00010 Glycolysis / Gluconeogenesis
PATH: MAP00071 Fatty acid metabolism
PATH: MAP00120 Bile acid biosynthesis
PATH: MAP00350 Tyrosine metabolism
PATH: MAP00561 Glycerolipid metabolism
GENES ECO: b0356 b1241 b1478 b3589
ECE: Z0456 Z2016 Z2232 Z5010
ECS: ECs0411 ECs1741 ECs2082 ECs4466
HIN: HI0185
XFA: XF1746 XF2389
VCH: VC1147 VC2033
PAE: PA2119 PA2158 PA2188 PA3629 PA5427
PMU: PM1453
NME: NMB0546 NMB1304
NMA: NMA0725 NMA1518
MLO: mlr0872 mlr1136 mlr1178
CCR: CC2516 CC3029
BSU: BS2776 BS3211
BHA: BH1829
LLA: L13145 L55758
SPY: SPy0044
MTU: Rv0761c Rv1862 Rv2259
MLE: ML1784 ML2053
SYN: sll0990
AAE: aq_1240 aq_1362
TMA: TM0111 TM0920
AFU: AF0024 AF0339 AF2019 AF2101
HAL: VNG1821G
TAC: Ta0832 Ta0833 Ta0841
TVO: TVG0387048 TVG0995648 TVG1348694
PHO: PH0743
PAB: PAB1511
APE: APE1245 APE1557 APE1963 APE2239
SSO: SSO0472 SSO0764 SSO1220 SSO1300 SSO1646 SSO2334 SSO2441
SSO2494 SSO2501 SSO2536 SSO2717 SSO2800 SSO2878
SCE: YBR145W YDL168W YGL256W YMR083W YMR303C YOL086C
SPO: ADH1 SPAC5H10.06C SPCC13B11.04C
ATH: At1g77120
CEL: K12G11.3 K12G11.4
DME: CG3425 CG3481 CG6598
MMU: 1098256 87921 87926 87929
HSA: 124 125 126 127 128 130 131
DISEASE MIM: 103700 Alcohol dehydrogenase (class I), alpha polypeptide
MIM: 103720 Alcohol dehydrogenase (class I), beta polypeptide
MIM: 103730 Alcohol dehydrogenase (class I), gamma polypeptide
MIM: 103740 Alcohol dehydrogenase (class II), pi polypeptide
MIM: 600086 Alcohol dehydrogenase-7
STRUCTURES PDB: 1A4U 1A71 1A72 1ADB 1ADC 1ADF 1ADG 1AGN 1AXE 1AXG
1B14 1B15 1B16 1B2L 1BTO 1CDO 1D1S 1D1T 1DDA 1DEH
1E3E 1E3I 1E3L 1EE2 1HDX 1HDY 1HDZ 1HET 1HEU 1HF3
1HLD 1HSO 1HSZ 1HT0 1HTB 1LDE 1LDY 1QLH 1QLJ 1TEH
2OHX 2OXI 3BTO 3HUD 5ADH 6ADH 7ADH
DBLINKS IUBMB Enzyme Nomenclature: 1.1.1.1
ExPASy - ENZYME nomenclature database: 1.1.1.1
WIT (What Is There) Metabolic Reconstruction: 1.1.1.1
BRENDA, the Enzyme Database: 1.1.1.1
SCOP (Structural Classification of Proteins): 1.1.1.1
///
ENTRY EC 1.1.1.62
NAME Estradiol 17beta-dehydrogenase
CLASS Oxidoreductases
Acting on the CH-OH group of donors
With NAD+ or NADP+ as acceptor
SYSNAME Estradiol-17beta:NAD(P)+ 17-oxidoreductase
REACTION Estradiol-17beta + NAD+ or NADP+ = Estrone + NADH or NADPH
SUBSTRATE Estradiol-17beta
(S)-20-Hydroxypregn-4-en-3-one
NAD+
NADP+
PRODUCT Estrone
(S)-Pregn-4-en-3,20-dione
NADH
NADPH
COMMENT Also acts on (S)-20-hydroxypregn-4-en-3-one and related
compounds, oxidizing the (S)-20-group. B-specific with respect
to NAD(P)+ (cf. EC 1.1.1.149).
PATHWAY PATH: MAP00150 Androgen and estrogen metabolism
GENES CEL: F11A5.12
DME: CG1444 CG3415
HSA: 3292 3293 3294 3295 3296 51478
DISEASE MIM: 109685 Hydroxysteroid (17-beta) dehydrogenase 2
MIM: 264300 Hydroxysteroid (17-beta) dehydrogenase 3
STRUCTURES PDB: 1FDT 1FDS 1FDV 1FDW 1IOL 3DHE 1EQU 1DHT 1BHS 1A27
1FDU
DBLINKS IUBMB Enzyme Nomenclature: 1.1.1.62
ExPASy - ENZYME nomenclature database: 1.1.1.62
WIT (What Is There) Metabolic Reconstruction: 1.1.1.62
BRENDA, the Enzyme Database: 1.1.1.62
SCOP (Structural Classification of Proteins): 1.1.1.62
///
ENTRY EC 1.1.1.68
NAME Transferred to EC 1.7.99.5
CLASS Oxidoreductases
Acting on the CH-OH group of donors
With NAD+ or NADP+ as acceptor
COMMENT Transferred entry. Now EC 1.7.99.5 -
5,10-Methylenetetrahydrofolate reductase (FADH2).
DBLINKS IUBMB Enzyme Nomenclature: 1.1.1.68
ExPASy - ENZYME nomenclature database: 1.1.1.68
WIT (What Is There) Metabolic Reconstruction: 1.1.1.68
///
ENTRY EC 1.6.5.3
NAME NADH dehydrogenase (ubiquinone)
Ubiquinone reductase
Type I dehydrogenase
Complex I dehydrogenase
CLASS Oxidoreductases
Acting on NADH or NADPH
With quinone or related compound as acceptor
SYSNAME NADH:ubiquinone oxidoreductase
REACTION NADH + Ubiquinone = NAD+ + Ubiquinol
SUBSTRATE NADH
Ubiquinone
PRODUCT NAD+
Ubiquinol
COFACTOR FAD
Iron
Sulfur
COMMENT A flavoprotein (FAD) containing iron-sulfur contres. The complex,
present in mitochondria, can be degraded to form EC 1.6.99.3.
PATHWAY PATH: MAP00130 Ubiquinone biosynthesis
PATH: MAP00190 Oxidative phosphorylation
GENES ECO: b2276 b2277 b2278 b2279 b2280 b2281 b2282 b2283 b2284 b2285
b2286 b2287 b2288
ECE: Z3534 Z3536 Z3537 Z3538 Z3539 Z3540 Z3541 Z3542 Z3543 Z3544
Z3545 Z3546 Z3547
ECS: ECs3160 ECs3161 ECs3162 ECs3163 ECs3164 ECs3165 ECs3166
ECs3167 ECs3168 ECs3169 ECs3170 ECs3171 ECs3172
XFA: XF0305 XF0306 XF0307 XF0308 XF0309 XF0310 XF0311 XF0312 XF0313
XF0314 XF0315 XF0316 XF0317 XF0318
VCH: VC1581 VCA0155 VCA0157
PAE: PA1054 PA1056 PA1883 PA2637 PA2638 PA2639 PA2640 PA2641 PA2642
PA2643 PA2644 PA2645 PA2646 PA2647 PA2648 PA2649
BUC: BU154 BU155 BU156 BU157 BU158 BU159 BU160 BU161 BU162 BU163
BU164 BU165 BU166
NME: NMB0241 NMB0242 NMB0243 NMB0244 NMB0245 NMB0246 NMB0249
NMB0250 NMB0251 NMB0253 NMB0254 NMB0257 NMB0258 NMB0259
NMA: NMA0002 NMA0005 NMA0006 NMA0008 NMA0009 NMA0010 NMA0014
NMA0015 NMA0016 NMA0017 NMA0018 NMA0019 NMA0747 NMA2228 NMA2229
HPY: HP1260 HP1261 HP1262 HP1263 HP1264 HP1265 HP1266 HP1267 HP1268
HP1269 HP1270 HP1271 HP1272 HP1273
HPJ: jhp1181 jhp1182 jhp1183 jhp1184 jhp1185 jhp1186 jhp1187
jhp1188 jhp1189 jhp1190 jhp1191 jhp1192 jhp1193 jhp1194
CJE: Cj1566c Cj1567c Cj1568c Cj1569c Cj1570c Cj1571c Cj1572c
Cj1573c Cj1574c Cj1575c Cj1576c Cj1577c Cj1578c Cj1579c
RPR: RP115 RP282 RP283 RP284 RP353 RP354 RP355 RP356 RP357 RP537
RP790 RP791 RP792 RP793 RP795 RP796 RP797
MLO: mll1352 mll1354 mll1355 mll1357 mll1358 mll1359 mll1361
mll1362 mll1364 mll1365 mll1366 mll1367 mll1369 mll1371
mll1372 mll5193 mll5397 mll5398
CCR: CC1937 CC1938 CC1939 CC1940 CC1941 CC1942 CC1945 CC1946 CC1947
CC1950 CC1952 CC1954 CC1955 CC1956
BSU: BS0231
MTU: Rv3145 Rv3146 Rv3147 Rv3148 Rv3149 Rv3150 Rv3151 Rv3152 Rv3153
Rv3154 Rv3155 Rv3156 Rv3157 Rv3158
SYN: sll0026 sll0027 sll0223 sll0519 sll0520 sll0521 sll0522
sll1220 sll1221 sll1223 sll1732 sll1733 slr0261 slr0331
slr0844 slr1279 slr1280 slr1281 slr1291 slr2007 slr2009
DRA: DR0880 DR1492 DR1493 DR1494 DR1495 DR1496 DR1497 DR1498 DR1499
DR1500 DR1501 DR1503 DR1504 DR1505 DR1506
AAE: aq_1310 aq_1312 aq_1314 aq_1315 aq_1317 aq_1318 aq_1319
aq_1320 aq_1321 aq_1322 aq_135 aq_1373 aq_1374 aq_1375 aq_1377
aq_1378 aq_1379 aq_1382 aq_1383 aq_1385 aq_437 aq_551 aq_573
aq_574 aq_866
TMA: TM0010 TM0011 TM0012 TM0201 TM0228 TM1105 TM1211 TM1212 TM1213
TM1214 TM1215 TM1216 TM1424 TM1425 TM1426
MJA: MJ0520 MJ1309 MJ1362
MTH: MTH1237 MTH1246 MTH1548 MTH1549 MTH393
AFU: AF1823 AF1824 AF1825 AF1826 AF1827 AF1828 AF1829 AF1830 AF1831
HAL: VNG0635G VNG0636G VNG0637G VNG0639G VNG0640G VNG0641C VNG0643G
VNG0646G VNG0647G VNG0648G
TAC: Ta0959 Ta0960 Ta0961 Ta0962 Ta0964 Ta0965 Ta0966 Ta0967 Ta0968
Ta0969 Ta0970
TVO: TVG1157047 TVG1158465 TVG1160017 TVG1161017 TVG1162018
TVG1162541 TVG1162786 TVG1163214 TVG1164251 TVG1165354
TVG1165809 TVG1166270
PHO: PH0941 PH0942 PH1431 PH1446 PH1447 PH1448 PH1449 PH1450 PH1451
PH1452 PH1453
PAB: PAB0488 PAB0490 PAB0492 PAB0493 PAB0494 PAB0495 PAB0496
PAB0805 PAB0806 PAB1888 PAB2416
APE: APE1410 APE1411 APE1415 APE1417 APE1418 APE1419 APE1421
APE1422 APE1426 APE1428 APE1430
SSO: SSO0322 SSO0323 SSO0324 SSO0325 SSO0326 SSO0327 SSO0328
SSO0329 SSO0665
SCE: YKL192C
SPO: SPAC11E3.12 SPAC4H3.09 SPBC18E5.10
ATH: AT4g02580 AT5g08530 AT5g11770 AT5g37510 At1g16700 At1g65290
At1g79010 At1g79200 At2g02050 At2g20360 At2g44620
CEL: C09H10.3 C16A3.4 C18E9.4 C25A1.13 C33A12.1 D2030.4 F16B4.6
F22D6.4 F37C12.3 F44G4.2 F53F4.10 F59C6.5 K04G7.4 K09A9.5
T10E9.7 T20H4.5 T26A5.3 W10D5.2 Y51H1A.3a Y51H1A.3b Y57G11C.12
Y63D3A.7
DME: CG10320 CG11423 CG11913 CG12079 CG15328 CG15434 CG1970 CG2014
CG2286 CG3192 CG3621 CG3683 CG3944 CG5548 CG5703 CG6020 CG6343
CG6463 CG6485 CG6914 CG7712 CG8102 CG8844 CG9140 CG9160
CG9160_1 CG9172 CG9306 CG9762
HSA: 4535 4536 4537 4538 4539 4540 4541 4694 4695 4696 4697 4698
4700 4701 4702 4704 4705 4706 4707 4708 4709 4710 4711 4712
4713 4714 4715 4716 4717 4718 4719 4720 4722 4723 4724 4725
4726 4727 4728 4729 4731
DISEASE MIM: 300078 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1,
7.5kD
MIM: 601677 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
(13kD, B13)
DBLINKS IUBMB Enzyme Nomenclature: 1.6.5.3
ExPASy - ENZYME nomenclature database: 1.6.5.3
WIT (What Is There) Metabolic Reconstruction: 1.6.5.3
BRENDA, the Enzyme Database: 1.6.5.3
///
ENTRY EC 1.14.13.28
NAME 3,9-Dihydroxypterocarpan 6a-monooxygenase
3,9-Dihydroxypterocarpan 6a-hydroxylase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen
SYSNAME (6aR,11aR)-3,9-Dihydroxypterocarpan,NADPH:oxygen oxidoreductase
$ (6a-hydroxylating)
REACTION (6aR,11aR)-3,9-Dihydroxypterocarpan + NADPH + O2 =
(6aS,11aS)-3,6a,9-Trihydroxypterocarpan + NADP+ + H2O
SUBSTRATE (6aR,11aR)-3,9-Dihydroxypterocarpan
NADPH
O2
PRODUCT (6aS,11aS)-3,6a,9-Trihydroxypterocarpan
NADP+
H2O
COFACTOR Heme
COMMENT Possibly a heme-thiolate protein (P-450). The product of the
reaction is the biosynthetic precursor of the phytoalexin
glyceollin in soybean.
DBLINKS IUBMB Enzyme Nomenclature: 1.14.13.28
ExPASy - ENZYME nomenclature database: 1.14.13.28
WIT (What Is There) Metabolic Reconstruction: 1.14.13.28
BRENDA, the Enzyme Database: 1.14.13.28
///
ENTRY EC 2.4.1.68
NAME Glycoprotein 6-alpha-L-fucosyltransferase
GDPfucose--glycoprotein fucosyltransferase
CLASS Transferases
Glycosyltransferases
Hexosyltransferases
SYSNAME GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked
$ N-acetylglucosamine of N-acetyl-beta-D-glucosaminyl-1,2-alpha-
$D-mannosyl-1,3-(R1-alpha-1,6)-beta-D-mannosyl-1,4-beta-N-acetyl-
$D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl)asparagine 6-alpha-L-
$fucosyltransferase
REACTION GDP-L-fucose + N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-
$mannosyl-1,3-(R1-alpha-1,6)-beta-D-mannosyl-beta-N-acetyl-1,4-
$D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl)asparagine = GDP +
N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-
$(R1-alpha-1,6)-beta-D-mannosyl-1,4-beta-N-acetyl-D-glucosaminyl-
$1,4-(alpha-L-fucosyl-1,6)-N-acetyl-D-glucosaminyl)asparagine
SUBSTRATE GDP-L-fucose
N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-
$(R1-alpha-1,6)-beta-D-mannosyl-beta-N-acetyl-1,4-D-glucosaminyl-
$1,4-N-acetyl-D-glucosaminyl)asparagine
PRODUCT GDP
N4-(N-Acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-
$(R1-alpha-1,6)-beta-D-mannosyl-1,4-beta-N-acetyl-D-glucosaminyl-
$1,4-(alpha-L-fucosyl-1,6)-N-acetyl-D-glucosaminyl)asparagine
PATHWAY PATH: MAP00510 Glycoprotein biosynthesis
DBLINKS IUBMB Enzyme Nomenclature: 2.4.1.68
ExPASy - ENZYME nomenclature database: 2.4.1.68
WIT (What Is There) Metabolic Reconstruction: 2.4.1.68
BRENDA, the Enzyme Database: 2.4.1.68
///
ENTRY EC 3.1.1.6
NAME Acetylesterase
C-esterase (in animal tissues)
CLASS Hydrolases
Acting on ester bonds
Carboxylic ester hydrolases
SYSNAME Acetic-ester acetylhydrolase
REACTION an Acetic ester + H2O = an Alcohol + Acetate
SUBSTRATE Acetic ester
H2O
PRODUCT Alcohol
Acetate
GENES MMU: 95428
STRUCTURES PDB: 1BS9 1G66 2AXE
DBLINKS IUBMB Enzyme Nomenclature: 3.1.1.6
ExPASy - ENZYME nomenclature database: 3.1.1.6
WIT (What Is There) Metabolic Reconstruction: 3.1.1.6
UM-BBD (Biocatalysis/Biodegradation Database): 3.1.1.6
BRENDA, the Enzyme Database: 3.1.1.6
SCOP (Structural Classification of Proteins): 3.1.1.6
///
ENTRY EC 2.7.2.1
NAME Acetate kinase
Acetokinase
CLASS Transferases
Transferring phosphorus-containing groups
Phosphotransferases with a carboxyl group as acceptor
SYSNAME ATP:acetate phosphotransferase
REACTION ATP + Acetate = ADP + Acetyl phosphate
SUBSTRATE ATP
Acetate
Propanoate
PRODUCT ADP
Acetyl phosphate
Propanoyl phosphate
COMMENT Propanoate also acts as acceptor, but more slowly.
PATHWAY PATH: MAP00620 Pyruvate metabolism
PATH: MAP00640 Propanoate metabolism
GENES ECO: ECOLI_2245
HIN: HI1204
BSU: ackA
MGE: MG357
MPN: G12_orf390
SYN: sll1299
DBLINKS University of Geneva ENZYME DATA BANK: 2.7.2.1
WIT (What Is There) Metabolic Reconstruction: 2.7.2.1
PIR: B49338 B49935 E64239 KIECAA
///
Testing Bio.KEGG.Enzyme on enzyme.irregular
ENTRY EC 1.14.18.1
NAME Monophenol monooxygenase
Tyrosinase
Phenolase
Monophenol oxidase
Cresolase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With another compound as one donor, and incorporation of one atom
of oxygen
SYSNAME Monophenol,L-dopa:oxygen oxidoreductase
REACTION L-Tyrosine + L-Dopa + O2 = L-Dopa + Dopaquinone + H2O
SUBSTRATE L-Tyrosine
L-Dopa
Benzenediol
O2
PRODUCT L-Dopa
Dopaquinone
H2O
COFACTOR Copper
COMMENT A group of copper proteins that also catalyse the reaction of
EC 1.10.3.1, if only benzenediols are available as substrate.
(EC 1.10.3.1 Catechol oxidase)
PATHWAY PATH: MAP00350 Tyrosine metabolism
PATH: MAP00740 Riboflavin metabolism
PATH: MAP00940 Flavonoids, stilbene and lignin biosynthesis
PATH: MAP00950 Alkaloid biosynthesis I
GENES DME: CG5779
MMU: 94856 98880
HSA: 7299
DISEASE MIM: 203100 Tyrosinase
DBLINKS IUBMB Enzyme Nomenclature: 1.14.18.1
ExPASy - ENZYME nomenclature database: 1.14.18.1
WIT (What Is There) Metabolic Reconstruction: 1.14.18.1
BRENDA, the Enzyme Database: 1.14.18.1
///
ENTRY EC 3.4.21.50
NAME Lysyl endopeptidase
Achromobacter proteinase I
Endoproteinase Lys-C
Ps-1
CLASS Hydrolases
Acting on peptide bonds (peptidases)
Serine endopeptidases
REACTION Preferential cleavage: Lys+, including -Lys-|-Pro-
SUBSTRATE Protein
Peptide
H2O
PRODUCT Protein
Peptide
COMMENT A chymotrypsin homologue isolated from Achromobacter lyticus.
Enzymes with similar specificity are produced by Lysobacter
enzymogenes (Endoproteinase Lys-C) and Pseudomonas aeruginosa
(Ps-1).
Also hydrolyses lysine amides and esters.
GENES MJA: MJ1468
MTH: MTH995
STRUCTURES PDB: 1ARC 1ARB
DBLINKS IUBMB Enzyme Nomenclature: 3.4.21.50
ExPASy - ENZYME nomenclature database: 3.4.21.50
WIT (What Is There) Metabolic Reconstruction: 3.4.21.50
BRENDA, the Enzyme Database: 3.4.21.50
SCOP (Structural Classification of Proteins): 3.4.21.50
///
Testing Bio.KEGG.Enzyme on enzyme.new
ENTRY EC 6.2.1.25
NAME benzoate---CoA ligase
benzoate---coenzyme A ligase
benzoyl-coenzyme A synthetase
benzoyl CoA synthetase (AMP forming)
CLASS Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
SYSNAME benzoate:CoA ligase (AMP-forming)
REACTION ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA [RN:R01422]
SUBSTRATE ATP [CPD:C00002]
benzoate [CPD:C00180]
CoA [CPD:C00010]
PRODUCT AMP [CPD:C00020]
diphosphate [CPD:C00013]
benzoyl-CoA [CPD:C00512]
COMMENT Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on
the corresponding chlorobenzoates.
PATHWAY PATH: ec00362 Benzoate degradation
PATH: ec00627 Aminobenzoate degradation
PATH: ec01100 Metabolic pathways
PATH: ec01120 Microbial metabolism in diverse environments
GENES REU: Reut_A1327
REH: H16_A1412 H16_B1918
RME: Rmet_1224
CTI: RALTA_A1325 RALTA_B1617
CNC: CNE_1c14400 CNE_2c18780
BXE: Bxe_A1419 Bxe_C0896
BPH: Bphy_1543
BPY: Bphyt_2700
BGL: bglu_2g11460
BUG: BC1001_2395
BGE: BC1002_1980
BGF: BC1003_1063
BRH: RBRH_00494
BPT: Bpet3574
AXY: AXYL_05035
AKA: TKWG_07570
RFR: Rfer_0216
POL: Bpro_1624 Bpro_2983
PNA: Pnap_2948
VEI: Veis_0730
DAC: Daci_0076
DEL: DelCs14_0077
VAP: Vapar_0089
VPE: Varpa_0102
CTT: CtCNB1_0097
RTA: Rta_22340
LCH: Lcho_3655
EBA: ebA2757 ebA5301
AZO: azo3052
TMZ: Tmz1t_3136
GME: Gmet_2143
GLO: Glov_2397
GEO: Geob_0200
GEM: GM21_2825
DMA: DMR_19390
DAS: Daes_3238
DPR: Despr_3172
DTI: Desti_5323
BJA: blr1077
BRA: BRADO6791
BBT: BBta_0747 BBta_6637
RPA: RPA0661 RPA0669
RPB: RPB_4656
RPC: RPC_1016 RPC_1025
RPD: RPD_1526 RPD_1534
RPE: RPE_0592 RPE_0604
RPT: Rpal_0728 Rpal_0736
RPX: Rpdx1_4117 Rpdx1_4125
RVA: Rvan_0044
SIL: SPO3697
JAN: Jann_0669
SWI: Swit_0829
RPM: RSPPHO_01133
MAG: amb2869
GYC: GYMC61_2828
GYA: GYMC52_1957
GCT: GC56T3_1519
SCB: SCAB_8391
SCT: SCAT_5491
SCY: SCATT_54890
BSD: BLASA_2555
AMD: AMED_8609
AMN: RAM_35745 RAM_44185
AMM: AMES_6861 AMES_8478
PDX: Psed_1491
DBLINKS ExplorEnz - The Enzyme Database: 6.2.1.25
IUBMB Enzyme Nomenclature: 6.2.1.25
ExPASy - ENZYME nomenclature database: 6.2.1.25
UM-BBD (Biocatalysis/Biodegradation Database): 6.2.1.25
BRENDA, the Enzyme Database: 6.2.1.25
CAS: 95329-17-2
///
Testing Bio.KEGG.Compound on compound.sample
ENTRY C00023
NAME Iron
Fe2+
Fe(II)
Fe3+
Fe(III)
FORMULA Fe
PATHWAY PATH: MAP00860 Porphyrin and chlorophyll metabolism
ENZYME 1.1.3.22 (C) 1.1.3.26 (C) 1.2.1.43 (C) 1.2.3.10 (C)
1.2.99.2 (C) 1.3.1.31 (C) 1.3.1.53 (C) 1.3.5.1 (C)
1.3.99.1 (C) 1.3.99.11 (C) 1.4.1.13 (C) 1.4.7.1 (C)
1.5.1.13 (C) 1.5.3.11 (C) 1.5.5.1 (C) 1.6.5.3 (C)
1.6.6.4 (C) 1.6.99.3 (C) 1.6.99.13 (R) 1.6.99.13 (R)
1.7.7.1 (C) 1.7.7.2 (C) 1.7.99.4 (C) 1.8.1.2 (C)
1.8.7.1 (C) 1.8.99.1 (C) 1.8.99.2 (C) 1.8.99.3 (C)
1.9.99.1 (R) 1.9.99.1 (R) 1.9.99.1 (C) 1.12.1.2 (C)
1.12.2.1 (C) 1.12.99.1 (C) 1.13.11.1 (C) 1.13.11.2 (C)
1.13.11.3 (C) 1.13.11.4 (C) 1.13.11.5 (C) 1.13.11.6 (C)
1.13.11.8 (C) 1.13.11.9 (C) 1.13.11.10 (C) 1.13.11.12 (C)
1.13.11.13 (C) 1.13.11.15 (C) 1.13.11.16 (C) 1.13.11.18 (C)
1.13.11.19 (C) 1.13.11.20 (C) 1.13.11.21 (C) 1.13.11.25 (C)
1.13.11.32 (C) 1.13.11.36 (C) 1.13.11.37 (C) 1.13.11.38 (C)
1.13.11.43 (C) 1.13.99.1 (C) 1.14.11.1 (C) 1.14.11.2 (C)
1.14.11.3 (C) 1.14.11.4 (C) 1.14.11.6 (C) 1.14.11.7 (C)
1.14.11.8 (C) 1.14.11.9 (C) 1.14.11.10 (C) 1.14.11.11 (C)
1.14.11.12 (C) 1.14.11.14 (C) 1.14.11.15 (C) 1.14.11.16 (C)
1.14.11.17 (C) 1.14.12.1 (C) 1.14.12.3 (C) 1.14.12.7 (C)
1.14.12.8 (C) 1.14.12.9 (C) 1.14.12.10 (C) 1.14.12.12 (C)
1.14.12.13 (C) 1.14.13.12 (C) 1.14.13.25 (C) 1.14.13.61 (C)
1.14.15.2 (C) 1.14.16.1 (C) 1.14.16.2 (C) 1.14.16.3 (C)
1.14.16.4 (C) 1.14.16.6 (C) 1.14.99.3 (R) 1.14.99.5 (C)
1.14.99.18 (C) 1.14.99.25 (C) 1.15.1.1 (C) 1.16.3.1 (R)
1.16.3.1 (R) 1.17.4.1 (C) 1.17.4.2 (C) 1.18.1.1 (C)
1.18.99.1 (C) 3.5.1.56 (C) 3.5.4.8 (C) 3.6.3.30 (R)
4.2.1.3 (C) 4.2.1.32 (C) 4.2.1.35 (C) 4.2.1.81 (C)
4.2.1.84 (C) 4.2.1.85 (C) 4.99.1.1 (R)
DBLINKS CAS: 7439-89-6
PROMISE: FEFEMAIN RNRR2 FERROXIDASE FERRITIN RUBRERYTHRIN
HAEMERYTHRIN PAP HAEMMAIN CATALASE CYTOCHROMES COX CYTB
BACFERRITIN CYTBHBL CYTB5 SULFOXIDASE CYTB562 CYTC CYTCI
CYTCII CYTCIII CYTCIV CYTC1 CYTC554 CYTCD1 CYTF HAO CYTBC1
GLOBINS PEROXIDASES ANPEROXIDASE FPBPEROXIDASE
HAEM_THIOLATE HAEMCPO NOS P450 NITROPHORIN SIROHAEM
FESMAIN FECYS4 DESULFOREDOXIN DFX RUBREDOXIN 2FE2S
ADRENODOXIN PLANTFRDX FEHASE XANTOXIDASE RIESKE ARHD 4FE4S
ACONITASE AOR BACFRDX DMSOR ENDONUCLEASE3 GPATASE HIPIP
NITROGENASE1 NITROGENASE2 NIFE PRISMANE TMADH FEMAIN AAAOH
EARCD FESOD IARCD IPNS LIPOXYGENASE NHASE PRCPB
///
ENTRY C00017
NAME Protein
PATHWAY PATH: MAP00251 Glutamate metabolism
PATH: MAP00252 Alanine and aspartate metabolism
PATH: MAP00290 Valine, leucine and isoleucine biosynthesis
PATH: MAP00330 Arginine and proline metabolism
PATH: MAP00450 Selenoamino acid metabolism
ENZYME 2.3.2.6 (R) 2.3.2.8 (R) 2.4.1.94 (R) 2.4.1.109 (R)
2.4.1.112 (R) 2.4.1.113 (R) 2.4.2.33 (R) 2.7.1.37 (R)
2.7.1.123 (R) 3.1.2.22 (R) 3.1.3.16 (R) 3.4.11.10 (R)
3.4.11.10 (R) 3.4.19.3 (R) 3.4.19.3 (R) 3.4.21.10 (R)
3.4.21.10 (R) 3.4.21.20 (R) 3.4.21.32 (R) 3.4.21.32 (R)
3.4.21.36 (R) 3.4.21.36 (R) 3.4.21.37 (R) 3.4.21.37 (R)
3.4.21.50 (R) 3.4.21.50 (R) 3.4.21.53 (R) 3.4.21.53 (R)
3.4.21.59 (R) 3.4.21.59 (R) 3.4.21.61 (R) 3.4.21.62 (R)
3.4.21.62 (R) 3.4.21.64 (R) 3.4.21.64 (R) 3.4.21.66 (R)
3.4.21.66 (R) 3.4.22.1 (R) 3.4.22.1 (R) 3.4.22.2 (R)
3.4.22.2 (R) 3.4.22.3 (R) 3.4.22.3 (R) 3.4.22.6 (R)
3.4.22.6 (R) 3.4.22.7 (R) 3.4.22.7 (R) 3.4.22.8 (R)
3.4.22.8 (R) 3.4.22.10 (R) 3.4.22.10 (R) 3.4.22.14 (R)
3.4.22.14 (R) 3.4.22.15 (R) 3.4.22.15 (R) 3.4.22.16 (R)
3.4.22.16 (R) 3.4.22.17 (R) 3.4.22.17 (R) 3.4.22.25 (R)
3.4.22.25 (R) 3.4.22.27 (R) 3.4.22.27 (R) 3.4.22.28 (R)
3.4.22.29 (R) 3.4.22.30 (R) 3.4.22.30 (R) 3.4.22.31 (R)
3.4.22.31 (R) 3.4.22.32 (R) 3.4.22.32 (R) 3.4.22.33 (R)
3.4.22.33 (R) 3.4.22.34 (R) 3.4.22.34 (R) 3.4.22.35 (R)
3.4.22.35 (R) 3.4.23.1 (R) 3.4.23.1 (R) 3.4.23.3 (R)
3.4.23.3 (R) 3.4.23.4 (R) 3.4.23.4 (R) 3.4.23.5 (R)
3.4.23.5 (R) 3.4.23.12 (R) 3.4.23.12 (R) 3.4.23.16 (R)
3.4.23.16 (R) 3.4.23.17 (R) 3.4.23.17 (R) 3.4.23.18 (R)
3.4.23.18 (R) 3.4.23.19 (R) 3.4.23.19 (R) 3.4.23.20 (R)
3.4.23.20 (R) 3.4.23.21 (R) 3.4.23.21 (R) 3.4.23.22 (R)
3.4.23.22 (R) 3.4.23.23 (R) 3.4.23.23 (R) 3.4.23.24 (R)
3.4.23.24 (R) 3.4.23.25 (R) 3.4.23.25 (R) 3.4.23.26 (R)
3.4.23.26 (R) 3.4.23.27 (R) 3.4.23.27 (R) 3.4.23.28 (R)
3.4.23.28 (R) 3.4.23.29 (R) 3.4.23.29 (R) 3.4.23.30 (R)
3.4.23.30 (R) 3.4.23.31 (R) 3.4.23.31 (R) 3.4.23.32 (R)
3.4.23.32 (R) 3.4.23.33 (R) 3.4.23.33 (R) 3.4.23.34 (R)
3.4.23.34 (R) 3.4.24.1 (R) 3.4.24.1 (R) 3.4.24.3 (R)
3.4.24.6 (R) 3.4.24.6 (R) 3.4.24.7 (R) 3.4.24.11 (R)
3.4.24.11 (R) 3.4.24.12 (R) 3.4.24.12 (R) 3.4.24.15 (R)
3.4.24.15 (R) 3.4.24.17 (R) 3.4.24.17 (R) 3.4.24.18 (R)
3.4.24.18 (R) 3.4.24.20 (R) 3.4.24.20 (R) 3.4.24.21 (R)
3.4.24.21 (R) 3.4.24.22 (R) 3.4.24.22 (R) 3.4.24.23 (R)
3.4.24.24 (R) 3.4.24.25 (R) 3.4.24.25 (R) 3.4.24.26 (R)
3.4.24.27 (R) 3.4.24.27 (R) 3.4.24.28 (R) 3.4.24.28 (R)
3.4.24.29 (R) 3.4.24.29 (R) 3.4.24.30 (R) 3.4.24.30 (R)
3.4.24.31 (R) 3.4.24.31 (R) 3.4.24.32 (R) 3.4.24.32 (R)
3.4.24.33 (R) 3.4.24.33 (R) 3.4.24.34 (R) 3.4.24.36 (R)
3.4.24.36 (R) 3.4.24.37 (R) 3.4.24.37 (R) 3.4.24.38 (R)
3.4.24.38 (R) 3.4.24.39 (R) 3.4.24.39 (R) 3.4.24.40 (R)
3.4.24.40 (R) 3.4.24.41 (R) 3.4.24.41 (R) 3.4.24.42 (R)
3.4.24.42 (R) 3.4.24.43 (R) 3.4.24.43 (R) 3.4.24.44 (R)
3.4.24.44 (R) 3.4.24.45 (R) 3.4.24.45 (R) 3.4.24.46 (R)
3.4.24.46 (R) 3.4.24.47 (R) 3.4.24.47 (R) 3.4.24.48 (R)
3.4.24.48 (R) 3.4.24.49 (R) 3.4.24.49 (R) 3.4.24.50 (R)
3.4.24.50 (R) 3.4.24.51 (R) 3.4.24.51 (R) 3.4.24.52 (R)
3.4.24.52 (R) 3.4.24.53 (R) 3.4.24.53 (R) 3.4.24.54 (R)
3.4.24.54 (R) 3.4.99.43 (R) 3.4.99.43 (R) 3.4.99.46 (R)
3.4.99.46 (R) 6.2.1.19 (R)
///
ENTRY C00099
NAME beta-Alanine
3-aminopropionic acid
3-Aminopropanoate
FORMULA C3H7NO2
PATHWAY PATH: MAP00240 Pyrimidine metabolism
PATH: MAP00252 Alanine and aspartate metabolism
PATH: MAP00410 beta-Alanine metabolism
PATH: MAP00640 Propanoate metabolism
PATH: MAP00770 Pantothenate and CoA biosynthesis
ENZYME 1.5.1.26 (R) 2.6.1.18 (R) 2.6.1.19 (R) 2.6.1.55 (R)
3.4.13.3 (R) 3.4.13.5 (R) 3.4.13.20 (R) 3.5.1.6 (R)
3.5.1.21 (R) 3.5.1.22 (R) 3.5.3.17 (R) 4.1.1.11 (R)
4.1.1.15 (R) 6.3.2.1 (R) 6.3.2.11 (R) 6.3.2.23 (R)
DBLINKS CAS: 107-95-9
///
ENTRY C00294
NAME Inosine
FORMULA C10H12N4O5
PATHWAY PATH: MAP00230 Purine metabolism
ENZYME 1.1.3.28 (R) 2.7.1.73 (R) 3.2.2.2 (R) 3.5.4.4 (R)
3.5.4.17 (R)
DBLINKS CAS: 58-63-9
///
ENTRY C00298
NAME Trypsin
ENZYME 3.4.21.9 (R) 3.4.23.18 (R) 3.4.23.20 (R) 3.4.23.24 (R)
3.4.23.26 (R)
///
ENTRY C00348
NAME Undecaprenyl phosphate
PATHWAY PATH: MAP00550 Peptideglycan biosynthesis
ENZYME 2.4.1.54 (R) 2.7.1.66 (R) 2.7.8.6 (R) 2.7.8.13 (R)
3.6.1.27 (R)
///
ENTRY C00349
NAME 2-Methyl-3-oxopropanoate
3-Oxo-2-methylpropanoate
Methylmalonate semialdehyde
FORMULA C4H6O3
ENZYME 1.1.1.31 (R) 1.2.1.27 (R) 2.6.1.22 (R) 2.6.1.40 (R)
2.6.1.61 (R)
///
ENTRY C01386
NAME NH2Mec
ENZYME 3.4.22.32 (R)
///
Testing Bio.KEGG.Compound on compound.irregular
ENTRY C01454
NAME Toluate
p-Toluate
p-Toluic acid
4-Methylbenzoic acid
Toluenecarboxylic acid
Crithminic acid
FORMULA C8H8O2
MASS 136.0524
PATHWAY PATH: map00622 Toluene and xylene degradation
ENZYME 1.2.1.7 1.14.12.-
DBLINKS CAS: 99-94-5
PubChem: 4631
ChEBI: 36635
3DMET: B00292
///
ENTRY C06876
NAME Nitrosobenzene
FORMULA C6H5NO
MASS 107.0371
PATHWAY PATH: map00626 Naphthalene and anthracene degradation
ENZYME 1.6.6.-
DBLINKS CAS: 586-96-9
PubChem: 9093
3DMET: B01057
///
Testing Bio.KEGG.Map on map00950.rea
(R)-N-Methylcoclaurine + (S)-Coclaurine + NADPH + O2 <=> 2'-Norberbamunine + 2 H2O + NADP
(R)-N-Methylcoclaurine + (S)-N-Methylcoclaurine + NADPH + O2 <=> Berbamunine + 2 H2O + NADP
(R)-Norreticuline + S-Adenosyl-L-methionine <=> (R)-Reticuline + S-Adenosyl-L-homocysteine
(R)-Reticuline + NADPH + O2 <=> 2 H2O + NADP+ + Salutaridine
(S)-3'-Hydroxycoclaurine + S-Adenosyl-L-methionine <=> (S)-Norreticuline + S-Adenosyl-L-homocysteine
(S)-6-O-Methylnorlaudanosoline + S-Adenosyl-L-methionine <=> (S)-Nororientaline + S-Adenosyl-L-homocysteine
(S)-Canadine + 2 O2 <=> Berberine + 2 H2O2
(S)-Cheilanthifoline + NADPH + O2 <=> (S)-Stylopine + 2 H2O + NADP+
(S)-Coclaurine + S-Adenosyl-L-methionine <=> (S)-N-Methylcoclaurine + S-Adenosyl-L-homocysteine
(S)-N-Methylcoclaurine <=> (S)-3'-Hydroxy-N-methylcoclaurine
(S)-Norcoclaurine + S-Adenosyl-L-methionine <=> (S)-Coclaurine + S-Adenosyl-L-homocysteine
(S)-Norlaudanosoline + S-Adenosyl-L-methionine <=> (S)-6-O-Methylnorlaudanosoline + S-Adenosyl-L-homocysteine
(S)-Norreticuline + S-Adenosyl-L-methionine <=> (S)-Reticuline + S-Adenosyl-L-homocysteine
(S)-Reticuline + O2 <=> (S)-Scoulerine + H2O2
(S)-Scoulerine + NADPH + O2 <=> (S)-Cheilanthifoline + 2 H2O + NADP+
(S)-Scoulerine + S-Adenosyl-L-methionine <=> (S)-Tetrahydrocolumbamine + S-Adenosyl-L-homocysteine
(S)-Stylopine + S-Adenosyl-L-methionine <=> (S)-cis-N-methylstylopine
(S)-Tetrahydrocolumbamine + 2 O2 <=> Columbamine + 2 H2O2
(S)-Tetrahydrocolumbamine + NADPH + O2 <=> (S)-Canadine + 2 H2O + NADP+
(S)-Tetrahydrocolumbamine + S-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteine + Tetrahydropalmatine
(S)-cis-N-methylstylopine <=> Protopine
1,2-Dehydroreticuline + NADPH <=> (R)-Reticuline + NADP+
10-Hydroxydihydrosanguinarine + S-Adenosyl-L-methionine <=> Dihydrochelirubine + S-Adenosyl-L-homocysteine
12-Hydroxydihydrochelirubine + S-Adenosyl-L-methionine <=> Dihydromacarpine + S-Adenosyl-L-homocysteine
2 (R)-N-Methylcoclaurine + NADPH + O2 <=> Guattegaumerine + 2 H2O + NADP
2 Columbamine + O2 <=> 2 Berberine + 2 H2O
2-Oxoglutarate + L-Tyrosine <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate
2-Oxoglutarate + L-Tyrosine <=> 4-Hydroxyphenylpyruvate + L-Glutamate
2-Oxoglutarate + L-Tyrosine <=> 4-Hydroxyphenylpyruvate + L-Glutamate
3'-Hydroxy-N-methyl-(S)-coclaurine + S-Adenosyl-L-methionine <=> (S)-Reticuline + S-Adenosyl-L-homocysteine
3,4-Dihydroxyphenylacetaldehyde + Dopamine <=> (S)-Norlaudanosoline + H2O
4-Hydroxyphenylacetaldehyde + Dopamine <=> (S)-Norcoclaurine + H2O
4-Hydroxyphenylpyruvate <=> 4-Hydroxyphenylacetaldehyde + CO2
6-Hydroxyprotopine <=> Dihydrosanguinarine
7-O-Acetylsalutaridinol <=> Thebaine
Acetyl-CoA + Salutaridinol <=> 7-O-Acetylsalutaridinol + CoA
Codeinone + NADPH <=> Codeine + NADP+
Columbamine + S-Adenosyl-L-methionine <=> Palmatine + S-Adenosyl-L-homocysteine
Dihydrochelirubine + O2 <=> Chelirubine + H2O2
Dihydrochelirubine <=> 12-Hydroxychelirubine
Dihydromacarpine + O2 <=> H2O2 + Macarpine
Dihydrosanguinarine + NADPH + O2 <=> 10-Hydroxydihydrosanguinarine + H2O + NADP+
Dihydrosanguinarine + O2 <=> H2O2 + Sanguinarine
H2O + L-Tyrosine + O2 <=> 4-Hydroxyphenylpyruvate + H2O2 + NH3
L-Tyrosine <=> CO2 + Tyramine
L-Tyrosine <=> CO2 + Tyramine
Morphine + NAD+ <=> Morphinone + NADH
Morphine + NADP+ <=> Morphinone + NADPH
Morphinone <=> Codeine
NADPH + O2 + Protopine <=> 6-Hydroxyprotopine + H2O + NADP+
NADPH + Salutaridine <=> NADP+ + Salutaridinol
Neopinone <=> Codeinone
Oripavine <=> Morphinone
Thebaine <=> Neopinone
Thebaine <=> Oripavine
Tyramine <=> Dopamine
|
