File: text_2011L_phiblast_002.txt

package info (click to toggle)
python-biopython 1.78%2Bdfsg-4
  • links: PTS, VCS
  • area: main
  • in suites: bullseye
  • size: 65,756 kB
  • sloc: python: 221,141; xml: 178,777; ansic: 13,369; sql: 1,208; makefile: 131; sh: 70
file content (1414 lines) | stat: -rw-r--r-- 61,738 bytes parent folder | download | duplicates (11)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
1001
1002
1003
1004
1005
1006
1007
1008
1009
1010
1011
1012
1013
1014
1015
1016
1017
1018
1019
1020
1021
1022
1023
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
1034
1035
1036
1037
1038
1039
1040
1041
1042
1043
1044
1045
1046
1047
1048
1049
1050
1051
1052
1053
1054
1055
1056
1057
1058
1059
1060
1061
1062
1063
1064
1065
1066
1067
1068
1069
1070
1071
1072
1073
1074
1075
1076
1077
1078
1079
1080
1081
1082
1083
1084
1085
1086
1087
1088
1089
1090
1091
1092
1093
1094
1095
1096
1097
1098
1099
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112
1113
1114
1115
1116
1117
1118
1119
1120
1121
1122
1123
1124
1125
1126
1127
1128
1129
1130
1131
1132
1133
1134
1135
1136
1137
1138
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
1149
1150
1151
1152
1153
1154
1155
1156
1157
1158
1159
1160
1161
1162
1163
1164
1165
1166
1167
1168
1169
1170
1171
1172
1173
1174
1175
1176
1177
1178
1179
1180
1181
1182
1183
1184
1185
1186
1187
1188
1189
1190
1191
1192
1193
1194
1195
1196
1197
1198
1199
1200
1201
1202
1203
1204
1205
1206
1207
1208
1209
1210
1211
1212
1213
1214
1215
1216
1217
1218
1219
1220
1221
1222
1223
1224
1225
1226
1227
1228
1229
1230
1231
1232
1233
1234
1235
1236
1237
1238
1239
1240
1241
1242
1243
1244
1245
1246
1247
1248
1249
1250
1251
1252
1253
1254
1255
1256
1257
1258
1259
1260
1261
1262
1263
1264
1265
1266
1267
1268
1269
1270
1271
1272
1273
1274
1275
1276
1277
1278
1279
1280
1281
1282
1283
1284
1285
1286
1287
1288
1289
1290
1291
1292
1293
1294
1295
1296
1297
1298
1299
1300
1301
1302
1303
1304
1305
1306
1307
1308
1309
1310
1311
1312
1313
1314
1315
1316
1317
1318
1319
1320
1321
1322
1323
1324
1325
1326
1327
1328
1329
1330
1331
1332
1333
1334
1335
1336
1337
1338
1339
1340
1341
1342
1343
1344
1345
1346
1347
1348
1349
1350
1351
1352
1353
1354
1355
1356
1357
1358
1359
1360
1361
1362
1363
1364
1365
1366
1367
1368
1369
1370
1371
1372
1373
1374
1375
1376
1377
1378
1379
1380
1381
1382
1383
1384
1385
1386
1387
1388
1389
1390
1391
1392
1393
1394
1395
1396
1397
1398
1399
1400
1401
1402
1403
1404
1405
1406
1407
1408
1409
1410
1411
1412
1413
1414
BLASTP 2.0.11 [Jan-20-2000]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|399896|sp|Q02134|HIS7_LACLA IMIDAZOLEGLYCEROL-PHOSPHATE
DEHYDRATASE (IGPD)
         (200 letters)

Database: data/swissprot
           82,258 sequences; 29,652,561 total letters

Searching..................................................done


Results from round 1


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

gi|399896|sp|Q02134|HIS7_LACLA IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   409  e-114
gi|462273|sp|P34047|HIS7_ARATH IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   198  6e-51
gi|2495230|sp|Q43072|HIS7_PEA IMIDAZOLEGLYCEROL-PHOSPHATE DEHYD...   196  4e-50
gi|123157|sp|P18787|HIS7_AZOBR IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   185  5e-47
gi|462275|sp|P34048|HIS7_WHEAT IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   181  8e-46
gi|123161|sp|P16247|HIS7_STRCO IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   178  7e-45
gi|462272|sp|Q05068|HIS7_ANASP IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   178  7e-45
gi|123158|sp|P06987|HIS7_ECOLI HISTIDINE BIOSYNTHESIS BIFUNCTIO...   175  8e-44
gi|1346293|sp|P48054|HIS7_SYNY3 IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   174  1e-43
gi|1170286|sp|P44327|HIS7_HAEIN HISTIDINE BIOSYNTHESIS BIFUNCTI...   168  8e-42
gi|2495224|sp|O06590|HIS7_MYCTU IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   167  2e-41
gi|123160|sp|P10368|HIS7_SALTY HISTIDINE BIOSYNTHESIS BIFUNCTIO...   166  2e-41
gi|2495226|sp|Q50504|HIS7_METTH PROBABLE IMIDAZOLEGLYCEROL-PHOS...   153  3e-37
gi|729718|sp|P40919|HIS7_CRYNE IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   152  7e-37
gi|3334215|sp|O33773|HIS7_SULSO PROBABLE IMIDAZOLEGLYCEROL-PHOS...   151  9e-37
gi|123159|sp|P28624|HIS7_PHYPR IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   149  3e-36
gi|729719|sp|P40374|HIS7_SCHPO IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   136  3e-32
gi|2495227|sp|P56090|HIS7_CANAL IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   128  9e-30
gi|2495225|sp|Q58109|HIS7_METJA PROBABLE IMIDAZOLEGLYCEROL-PHOS...   126  4e-29
gi|2495229|sp|Q92447|HIS7_PICPA IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   125  6e-29
gi|399897|sp|Q02986|HIS7_SACKL IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   125  6e-29
gi|2495228|sp|Q12578|HIS7_CANGA IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   123  2e-28
gi|2506514|sp|P06633|HIS7_YEAST IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   122  4e-28
gi|462274|sp|P34041|HIS7_TRIHA IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   106  3e-23
gi|1345641|sp|P49264|C7B1_THLAR CYTOCHROME P450 71B1 (CYPLXXIB1)      35  0.13
gi|1731346|sp|Q10698|YY29_MYCTU PROBABLE DIPEPTIDASE CY49.29C         32  1.1
gi|3287839|sp|Q01812|GLK4_RAT GLUTAMATE RECEPTOR, IONOTROPIC KA...    30  3.3
gi|3123025|sp|Q94637|VIT6_OSCBR VITELLOGENIN 6 PRECURSOR              29  5.6
gi|1174406|sp|P36126|SP14_YEAST PHOSPHOLIPASE D1 (PLD 1) (CHOLI...    29  9.7
gi|3287848|sp|Q16099|GLK4_HUMAN GLUTAMATE RECEPTOR, IONOTROPIC ...    29  9.7

>gi|399896|sp|Q02134|HIS7_LACLA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 200
           
 Score =  409 bits (1040), Expect = e-114
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60
           MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH
Sbjct: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60

Query: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120
           ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV
Sbjct: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120

Query: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180
           FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK
Sbjct: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180

Query: 181 QAVSIDESKVGEIPSSKGVL 200
           QAVSIDESKVGEIPSSKGVL
Sbjct: 181 QAVSIDESKVGEIPSSKGVL 200


>gi|462273|sp|P34047|HIS7_ARATH IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 270
           
 Score =  198 bits (499), Expect = 6e-51
 Identities = 99/198 (50%), Positives = 135/198 (68%), Gaps = 4/198 (2%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           RI  + R TKET + + INLDGTG AD S+GI FLDHML  L  H  FD+ +   GD   
Sbjct: 74  RIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFDVHVRATGD--- 130

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           V +D HH  ED+A+A+G  + + LG + GI R+G FT P+DEAL+   LD+SGRPYL ++
Sbjct: 131 VHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYN 190

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
            ++   Q++G YDT++ E FF++L   +G+TLH+ +  G+N+HHIIE  FK+ ARAL+QA
Sbjct: 191 LEIP-TQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGENSHHIIEATFKAFARALRQA 249

Query: 183 VSIDESKVGEIPSSKGVL 200
              D  + G IPSSKGVL
Sbjct: 250 TETDPRRGGTIPSSKGVL 267


>gi|2495230|sp|Q43072|HIS7_PEA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 281
           
 Score =  196 bits (492), Expect = 4e-50
 Identities = 96/199 (48%), Positives = 136/199 (68%), Gaps = 4/199 (2%)

Query: 2   TRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHE 61
           TR+  + R TKET + + INLDG+G AD STGI FLDHML  L  H  FD+ +   GD  
Sbjct: 84  TRVGEVKRVTKETNVSVKINLDGSGVADSSTGIPFLDHMLDQLASHGLFDVHVKATGD-- 141

Query: 62  TVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVF 121
            V +D HH  EDVA+A+G  + + LG++ GI R+G F+ P+DEAL+   LD+SGRP+L +
Sbjct: 142 -VHIDDHHTNEDVALAIGTALLQALGDRKGINRFGDFSAPLDEALIHVSLDLSGRPHLSY 200

Query: 122 HADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQ 181
           + D+   Q++G YDT++ E F +++   +G+TLH+ +  G+N+HHIIE  FK+ ARAL+Q
Sbjct: 201 NLDIP-TQRVGTYDTQVVEHFLQSIVNTSGMTLHIRQLAGRNSHHIIEATFKAFARALRQ 259

Query: 182 AVSIDESKVGEIPSSKGVL 200
           A   D  + G +PSSKGVL
Sbjct: 260 ATEYDPRRRGSVPSSKGVL 278


>gi|123157|sp|P18787|HIS7_AZOBR IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 207
           
 Score =  185 bits (465), Expect = 5e-47
 Identities = 91/194 (46%), Positives = 126/194 (64%), Gaps = 4/194 (2%)

Query: 7   ITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHETVGMD 66
           I RNT ET+I +++NLDGTG  D+ TG+GFLDHML  L+ HS  DL +   GD   V +D
Sbjct: 14  IERNTTETRIRVAVNLDGTGVYDVKTGVGFLDHMLEQLSRHSLMDLSVAAEGD---VHID 70

Query: 67  PHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFHADLS 126
            HH  E   IA+G+ +++ +G++ GI+RYG   +PMDE L    LD S RPYL++    S
Sbjct: 71  AHHTTEHSGIAIGQAVAKAVGDRKGIQRYGHAYVPMDETLTRVALDFSNRPYLIWKVSFS 130

Query: 127 GNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQAVSID 186
              K+G  DTE+  E+F+A A  AG+TLH+   YG+N HHI+E  +K+ ARAL+  + ID
Sbjct: 131 -RDKIGDMDTELFREWFQAFAMAAGVTLHVECLYGENNHHIVESCYKALARALRAGIEID 189

Query: 187 ESKVGEIPSSKGVL 200
             K   +PS+KG L
Sbjct: 190 PRKRDAVPSTKGTL 203


>gi|462275|sp|P34048|HIS7_WHEAT IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 195
           
 Score =  181 bits (455), Expect = 8e-46
 Identities = 93/194 (47%), Positives = 128/194 (65%), Gaps = 4/194 (2%)

Query: 7   ITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHETVGMD 66
           + R TKET + + INLDGTG A+ STGI FLDHML  L  H  FD+ +   GD     +D
Sbjct: 3   VKRVTKETNVHVKINLDGTGVANSSTGIPFLDHMLDQLASHGLFDVYVKATGDTH---ID 59

Query: 67  PHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFHADLS 126
            HH  ED+A+A+G  + + LG++ GI R+G FT P+DEA V   LD+SGRP+L     + 
Sbjct: 60  DHHSNEDIALAIGTALLQALGDRKGINRFGHFTAPLDEAAVEVILDLSGRPHLSCGLSIP 119

Query: 127 GNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQAVSID 186
             +++G YDT++ E FF++L   +G+TLH+ +  G N+HHIIE  FK+ ARAL+QA   D
Sbjct: 120 -TERVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGNNSHHIIEATFKAFARALRQATEYD 178

Query: 187 ESKVGEIPSSKGVL 200
             + G +PSSKGVL
Sbjct: 179 LRRQGTMPSSKGVL 192


>gi|123161|sp|P16247|HIS7_STRCO IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 197
           
 Score =  178 bits (447), Expect = 7e-45
 Identities = 89/200 (44%), Positives = 124/200 (61%), Gaps = 3/200 (1%)

Query: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60
           M+R+  + R TKET + + I+LDGTG+ DI+TG+GF DHML  L  H  FDL +   GD 
Sbjct: 1   MSRVGRVERTTKETSVLVEIDLDGTGKTDIATGVGFYDHMLDQLGRHGLFDLTVKTDGD- 59

Query: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120
             + +D HH IED A+ALG    + LG+K+GI R+G+ T+P+DE+L    +D+SGRPYLV
Sbjct: 60  --LHIDSHHTIEDTALALGAAFRQALGDKVGIYRFGNCTVPLDESLAQVTVDLSGRPYLV 117

Query: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180
                +    +G YD  MT     +    A + LH++  YG+N HHI+E  FK+ ARAL+
Sbjct: 118 HTEPENMAPMIGEYDVTMTRHILESFVAQAQVALHVHVPYGRNAHHIVECQFKALARALR 177

Query: 181 QAVSIDESKVGEIPSSKGVL 200
            A   D    G +PS+KG L
Sbjct: 178 YASERDPRAAGILPSTKGAL 197


>gi|462272|sp|Q05068|HIS7_ANASP IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 209
           
 Score =  178 bits (447), Expect = 7e-45
 Identities = 91/198 (45%), Positives = 131/198 (65%), Gaps = 4/198 (2%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           RI+ + R T ET +++++NLDGTG    +TGI FLDHML  ++ H   DL +   GD E 
Sbjct: 16  RIASVHRITGETNVQVTVNLDGTGICKAATGIPFLDHMLHQISSHGLIDLDVQAKGDWE- 74

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH  EDV I LG+ +++ LG++ GI R+G+F  P+DEALV   LD SGRP+L + 
Sbjct: 75  --IDDHHTNEDVGITLGQALAKALGDRKGIVRFGNFLAPLDEALVQVALDFSGRPHLSYG 132

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
             +   +++G YDT++  EFF AL  ++ +TLH+ +  G N+HHIIE  FK+ ARA + A
Sbjct: 133 LQIP-TERVGTYDTQLVREFFVALVNHSQMTLHIRQLDGINSHHIIEATFKAFARAARMA 191

Query: 183 VSIDESKVGEIPSSKGVL 200
           + +D  + G IPSSKGVL
Sbjct: 192 IEVDPRRAGTIPSSKGVL 209


>gi|123158|sp|P06987|HIS7_ECOLI HISTIDINE BIOSYNTHESIS BIFUNCTIONAL
           PROTEIN HISB [INCLUDES: IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD); HISTIDINOL-PHOSPHATASE ]
           Length = 355
           
 Score =  175 bits (438), Expect = 8e-44
 Identities = 91/198 (45%), Positives = 130/198 (64%), Gaps = 9/198 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R +H+ RNTKETQI++ + LD  G + I+TG+GF DHML  +  H  F ++I   GD   
Sbjct: 167 RYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGD--- 223

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           + +D HH +ED  +ALG+ +   LG+K GI R+G F +PMDE L  C LDISGRP+L + 
Sbjct: 224 LYIDDHHTVEDTGLALGEALKIALGDKRGICRFG-FVLPMDECLARCALDISGRPHLEYK 282

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
           A+ +  Q++G   TEM E FFR+L++  G+TLHL    G+N HH +E +FK+  R L+QA
Sbjct: 283 AEFT-YQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTK-GKNDHHRVESLFKAFGRTLRQA 340

Query: 183 VSIDESKVGEIPSSKGVL 200
           + ++      +PSSKGVL
Sbjct: 341 IRVEGD---TLPSSKGVL 355


>gi|1346293|sp|P48054|HIS7_SYNY3 IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 210
           
 Score =  174 bits (437), Expect = 1e-43
 Identities = 88/198 (44%), Positives = 129/198 (64%), Gaps = 4/198 (2%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R + + R TKET + +S+NL G+G   ++TG+ FLDHML  +  H   DL++   GD E 
Sbjct: 17  RAAAVHRVTKETDVRVSLNLMGSGLCHVATGVPFLDHMLHQIASHGLIDLEVNATGDIE- 75

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH  EDV I LG+ ++E LG++ GI R+G F  P+DEALV   LD SGRP+L + 
Sbjct: 76  --IDDHHTNEDVGITLGQALAEALGDRRGINRFGHFIAPLDEALVQVTLDFSGRPHLSYG 133

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
             +   +++G YDT++  EFF A+  ++ +TLH+ +  G N+HHIIE  FK+ ARA++ A
Sbjct: 134 LQIP-TERVGTYDTQLVREFFVAVVNHSQMTLHIRQLDGINSHHIIEATFKAFARAMRMA 192

Query: 183 VSIDESKVGEIPSSKGVL 200
           + +D  +   IPSSKGVL
Sbjct: 193 IEVDPRRADTIPSSKGVL 210


>gi|1170286|sp|P44327|HIS7_HAEIN HISTIDINE BIOSYNTHESIS BIFUNCTIONAL
           PROTEIN HISB [INCLUDES: IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD); HISTIDINOL-PHOSPHATASE ]
           Length = 362
           
 Score =  168 bits (421), Expect = 8e-42
 Identities = 89/198 (44%), Positives = 127/198 (63%), Gaps = 9/198 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R + + R TKET I++ + LD  G  +I TG+GF DHML  +  H  F + +   GD   
Sbjct: 174 RFAEVIRQTKETDIKVQVWLDEAGVNEIKTGVGFFDHMLDQIATHGGFRMNVQCKGD--- 230

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           + +D HH +ED A+ALG+ + + +G+K GI R+G F +PMDE    C LD+SGRP++ F+
Sbjct: 231 LWIDEHHTVEDTALALGQALKQAVGDKRGIARFG-FVLPMDECKAECALDLSGRPWIKFN 289

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
           A      K+G + TE+TE FF++LAF+   TLHLN   G N HH IE +FK+  R L+QA
Sbjct: 290 ACFK-RDKVGDFSTELTEHFFQSLAFSMLATLHLNV-TGNNDHHKIESLFKAFGRTLRQA 347

Query: 183 VSIDESKVGEIPSSKGVL 200
           + I+ +   E+PSSKGVL
Sbjct: 348 IRIEGN---EMPSSKGVL 362


>gi|2495224|sp|O06590|HIS7_MYCTU IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 210
           
 Score =  167 bits (418), Expect = 2e-41
 Identities = 92/207 (44%), Positives = 125/207 (59%), Gaps = 14/207 (6%)

Query: 2   TRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHE 61
           +R + I R T+E+ I + ++LDGTGQ  + TG+ F DHMLT L  H+ FDL +   GD E
Sbjct: 10  SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE 69

Query: 62  TVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVF 121
              ++ HH IED AIALG  + + LG+K GIRR+G   IPMDE L    +D+SGRPY V 
Sbjct: 70  ---IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVH 126

Query: 122 --------HADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFK 173
                   H  ++G+     Y T +    F +LA NA I LH+   YG++ HHI E  +K
Sbjct: 127 TGEPDHLQHTTIAGSSV--PYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYK 184

Query: 174 STARALKQAVSIDESKVGEIPSSKGVL 200
           + ARAL+QAV  D  +V  +PS+KG L
Sbjct: 185 AVARALRQAVEPD-PRVSGVPSTKGAL 210


>gi|123160|sp|P10368|HIS7_SALTY HISTIDINE BIOSYNTHESIS BIFUNCTIONAL
           PROTEIN HISB [INCLUDES: IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD); HISTIDINOL-PHOSPHATASE ]
           Length = 354
           
 Score =  166 bits (417), Expect = 2e-41
 Identities = 89/198 (44%), Positives = 129/198 (64%), Gaps = 10/198 (5%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R +H+ RNTKETQI++S+ LD  G + I+TG+GF DHML  +  H  F ++I   GD   
Sbjct: 167 RYAHVVRNTKETQIDVSVWLDREGNSKINTGVGFFDHMLDQIATHGGFRMEITVKGD--- 223

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           + +D HH +ED  +AL + +   L +K GI R+G F +PMDE L  C LDISGRP+L + 
Sbjct: 224 LYIDDHHTVEDTGLALREALKLALRDKRGICRFG-FVLPMDECL-ACALDISGRPHLEYK 281

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
           A+ +  Q++G   TEM E FFR+L++  G+TLHL    G+N HH +E +FK+  R ++QA
Sbjct: 282 AEFT-YQRVGNLSTEMIEHFFRSLSYTMGVTLHLKTK-GKNDHHRVESLFKAFGRTVRQA 339

Query: 183 VSIDESKVGEIPSSKGVL 200
           + ++      +PSSKGVL
Sbjct: 340 IRVEGD---TLPSSKGVL 354


>gi|2495226|sp|Q50504|HIS7_METTH PROBABLE
           IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD)
           Length = 194
           
 Score =  153 bits (382), Expect = 3e-37
 Identities = 81/198 (40%), Positives = 122/198 (60%), Gaps = 8/198 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R S  TR T ET +++ + +DG+G++ ++TG+GFLDHML  +  H   DL++   GD E 
Sbjct: 5   RRSMKTRETLETHVKVDLEIDGSGKSSVNTGLGFLDHMLESVARHGLLDLEVEARGDLE- 63

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH +EDVA+ LG+ + E LG+K GIRR     +PMD+AL T  LD+SGRPY V  
Sbjct: 64  --VDDHHTVEDVALTLGEALREALGDKSGIRRMAHAMVPMDDALATVALDLSGRPYTVLE 121

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
            +   +  +G   ++    F  +LA +A + +H +   G+N HH  E +FK+ A A++ A
Sbjct: 122 LEFD-DAVIGDVKSQNIGHFIESLAVSAAMNIHASVR-GRNDHHKAEALFKALALAIRDA 179

Query: 183 VSIDESKVGEIPSSKGVL 200
           V ++    GEIPS+KG L
Sbjct: 180 VRVEH---GEIPSTKGKL 194


>gi|729718|sp|P40919|HIS7_CRYNE IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 202
           
 Score =  152 bits (379), Expect = 7e-37
 Identities = 83/203 (40%), Positives = 120/203 (58%), Gaps = 11/203 (5%)

Query: 3   RISHITRNTKETQIELSINLDGTG-----QADISTGIGFLDHMLTLLTFHSDFDLKIIGH 57
           RI+ + R T ET I  +I+LD        + ++STGIGFLDHM T L  H    L++   
Sbjct: 4   RIASVERTTSETHISCTIDLDHIPGVTEQKINVSTGIGFLDHMFTALAKHGGMSLQLQCK 63

Query: 58  GDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRP 117
           GD   + +D HH  ED A+ALG+   + LG + GI+RYG    P+DE+L    +DIS RP
Sbjct: 64  GD---LHIDDHHTAEDCALALGEAFKKALGERKGIKRYGYAYAPLDESLSRAVIDISSRP 120

Query: 118 YLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTAR 177
           Y + H   +  +K+G   TEM     ++ AF AG+TLH++   G+N HHI E  FK+ A 
Sbjct: 121 YFMCHLPFT-REKVGDLSTEMVSHLLQSFAFAAGVTLHIDSIRGENNHHIAESAFKALAL 179

Query: 178 ALKQAVSIDESKVGEIPSSKGVL 200
           A++ A+S   +   ++PS+KGVL
Sbjct: 180 AIRMAIS--RTGGDDVPSTKGVL 200


>gi|3334215|sp|O33773|HIS7_SULSO PROBABLE
           IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD)
           Length = 193
           
 Score =  151 bits (378), Expect = 9e-37
 Identities = 88/201 (43%), Positives = 128/201 (62%), Gaps = 9/201 (4%)

Query: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHML-TLLTFHSDFDLKIIGHGD 59
           M+R ++ITR TKET+IE+ +++D  G+  +ST I F +HML TLLT+ +     I+   D
Sbjct: 1   MSRSANITRETKETKIEVLLDIDRKGEVKVSTPIPFFNHMLITLLTYMNS--TAIVSATD 58

Query: 60  HETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYL 119
              +  D HH++EDVAI LG  I   LG+K GI+R+    IPMD+ALV   LDIS R   
Sbjct: 59  K--LPYDDHHIVEDVAITLGLAIKTALGDKRGIKRFSHQIIPMDDALVLVSLDISNRGMA 116

Query: 120 VFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARAL 179
             + +L  ++ +GG  TE    FF++ A+N+GITLH+++  G NTHHIIE  FK+   AL
Sbjct: 117 FVNLNLKRSE-IGGLATENVPHFFQSFAYNSGITLHISQLSGYNTHHIIEASFKALGLAL 175

Query: 180 KQAVSIDESKVGEIPSSKGVL 200
            +A  I ++   EI S+KG++
Sbjct: 176 YEATRIVDN---EIRSTKGII 193


>gi|123159|sp|P28624|HIS7_PHYPR IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 452
           
 Score =  149 bits (373), Expect = 3e-36
 Identities = 86/198 (43%), Positives = 120/198 (60%), Gaps = 6/198 (3%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R ++I+R TKET I + ++LDGTG++ +S+GIGFLDHMLT L  HS FDL++   GD   
Sbjct: 260 REANISRVTKETSISVKLSLDGTGKSKVSSGIGFLDHMLTALAKHSRFDLELDCKGD--- 316

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH  ED A+ LG+     LG++ GI R+GS  +P+DEAL    +DIS R +   +
Sbjct: 317 TWIDDHHTTEDCALTLGEAFDVALGDRAGIARFGSACVPLDEALSRAIVDISSRAHSEIN 376

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
             L     +G   +EM   FF + A  A  TLH++   G+N HH  E  FK+ A AL+ A
Sbjct: 377 LQLV-RPSVGELSSEMITHFFESFASAALXTLHVDVLRGRNDHHRAEASFKALAVALRTA 435

Query: 183 VSIDESKVGEIPSSKGVL 200
           V  D +    +PS+KGVL
Sbjct: 436 VKHDAT--AGVPSTKGVL 451


>gi|729719|sp|P40374|HIS7_SCHPO IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 216
           
 Score =  136 bits (339), Expect = 3e-32
 Identities = 84/221 (38%), Positives = 114/221 (51%), Gaps = 29/221 (13%)

Query: 3   RISHITRNTKETQIELSINLD-----------------------GTGQADISTGIGFLDH 39
           R + + RNT ET+I ++I LD                       G     + TGIGFLDH
Sbjct: 2   RRAFVERNTNETKISVAIALDKAPLPEESNFIDELITSKHANQKGEQVIQVDTGIGFLDH 61

Query: 40  MLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFT 99
           M   L  H+ + L++   GD   + +D HH  ED AIALG    + +GN  G++R+G   
Sbjct: 62  MYHALAKHAGWSLRLYSRGD---LIIDDHHTAEDTAIALGIAFKQAMGNFAGVKRFGHAY 118

Query: 100 IPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEH 159
            P+DEAL    +D+SGRPY V    L   +K+G    EM      + +  AGITLH+   
Sbjct: 119 CPLDEALSRSVVDLSGRPYAVIDLGLK-REKVGELSCEMIPHLLYSFSVAAGITLHVTCL 177

Query: 160 YGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           YG N HH  E  FKS A A++ A S+  S   E+PS+KGVL
Sbjct: 178 YGSNDHHRAESAFKSLAVAMRAATSLTGS--SEVPSTKGVL 216


>gi|2495227|sp|P56090|HIS7_CANAL IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 223
           
 Score =  128 bits (318), Expect = 9e-30
 Identities = 81/227 (35%), Positives = 119/227 (51%), Gaps = 33/227 (14%)

Query: 1   MTRISHITRNTKETQIELSINLDG---------------------------TGQADISTG 33
           M+R + I R T ET+I++++NLDG                           +   ++ TG
Sbjct: 1   MSREALINRITNETKIQIALNLDGGKLELKESIFPNQSIIIDEHHAKQVSGSQYINVQTG 60

Query: 34  IGFLDHMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIR 93
           IGFLDHM+  L  HS + L +   GD   + +D HH  EDV I+LG    + LG   G++
Sbjct: 61  IGFLDHMIHALAKHSGWSLIVECIGD---LHIDDHHTAEDVGISLGMAFKQALGQIKGVK 117

Query: 94  RYGSFTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGIT 153
           R+G    P+DEAL    +D+S RP+ V    L   +K+G   TEM      + A   GIT
Sbjct: 118 RFGHGFAPLDEALSRAVVDLSNRPFAVIELGLK-REKIGDLSTEMIPHVLESFAGAVGIT 176

Query: 154 LHLNEHYGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           +H++   G N HH  E  FK+ A A+K+A+S  ++   +IPS+KGVL
Sbjct: 177 IHVDCLRGFNDHHRAESAFKALAIAIKEAIS--KTGKNDIPSTKGVL 221


>gi|2495225|sp|Q58109|HIS7_METJA PROBABLE
           IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD)
           Length = 197
           
 Score =  126 bits (313), Expect = 4e-29
 Identities = 80/196 (40%), Positives = 107/196 (53%), Gaps = 9/196 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           RI  + R TKET I L IN+DGTG+  I TGI F DH+L     H  FDL +   GD E 
Sbjct: 7   RIFEVMRETKETNIYLKINIDGTGKYKIDTGIPFFDHLLASFAKHGCFDLIVKARGDLE- 65

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH +EDV I LG  +++    K  I R+G   IPMD+A  T  +D+SGR Y V +
Sbjct: 66  --IDDHHTVEDVGICLGLALNQI--EKRNIFRFGWAIIPMDDARATVAIDLSGRSYCVGN 121

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
            +    + +G   TE    FF ++A    + +H  E  G+N HH  E +FK+   AL  A
Sbjct: 122 YE-PKREFVGDLATENINHFFESVASYGMLNIHY-EVIGKNEHHKAEALFKAFGVALDLA 179

Query: 183 VSIDESKVGEIPSSKG 198
             IDE K   + S+KG
Sbjct: 180 TKIDERK--GVISTKG 193


>gi|2495229|sp|Q92447|HIS7_PICPA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 224
           
 Score =  125 bits (311), Expect = 6e-29
 Identities = 84/223 (37%), Positives = 116/223 (51%), Gaps = 31/223 (13%)

Query: 3   RISHITRNTKETQIELSINLDG-------------------TGQA------DISTGIGFL 37
           R S I R T ET+I+++++LDG                     QA       ++TGIGFL
Sbjct: 7   RSSLIKRITNETKIQIALSLDGGPVSLAQSLFKDKDYSAEHAAQATSSQFISVNTGIGFL 66

Query: 38  DHMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGS 97
           DHML  L  H  + + I   GD   + +D HH  ED  IALG    E LG+  GI+R+GS
Sbjct: 67  DHMLHALAKHGGWSVIIECVGD---LHIDDHHSAEDTGIALGMAFKEALGHVRGIKRFGS 123

Query: 98  FTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLN 157
              P+DEAL    +D+S RPY V    L   +K+G    EM      + A  A +T+H++
Sbjct: 124 GFAPLDEALSRAVIDMSNRPYAVVDLGLK-REKIGDLSCEMIPHVLESFAQGAHVTMHVD 182

Query: 158 EHYGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
              G N HH  E  FK+ A A+K+A+S   +   +IPS+KGVL
Sbjct: 183 CLRGFNDHHRAESAFKALAIAIKEAIS--SNGTDDIPSTKGVL 223


>gi|399897|sp|Q02986|HIS7_SACKL IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 232
           
 Score =  125 bits (311), Expect = 6e-29
 Identities = 81/222 (36%), Positives = 119/222 (53%), Gaps = 30/222 (13%)

Query: 3   RISHITRNTKETQIELSINLDG------------------TGQA------DISTGIGFLD 38
           R + I+R T ET+I+++I+L+G                    QA      DI TG+GFLD
Sbjct: 16  RKAFISRITNETKIQIAISLNGGYIQIKDSILPAKKDDDVASQATQSQVIDIHTGVGFLD 75

Query: 39  HMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSF 98
           HM+  L  HS + L +   GD   + +D HH  ED  IALG+   E +G   G++R+G+ 
Sbjct: 76  HMIHALAKHSGWSLIVECIGD---LHIDDHHTTEDCGIALGQAFKEAMGAVRGVKRFGTG 132

Query: 99  TIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNE 158
             P+DEAL    +D+S RP+ V    L   + +G   TEM   F  + A  A ITLH++ 
Sbjct: 133 FAPLDEALSRAVVDLSNRPFAVIDLGLK-REMIGDLSTEMIPHFLESFAEAARITLHVDC 191

Query: 159 HYGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
             G N HH  E  FK+ A A+++A+S   +   ++PS+KGVL
Sbjct: 192 LRGFNDHHRSESAFKALAVAIREAIS--SNGTNDVPSTKGVL 231


>gi|2495228|sp|Q12578|HIS7_CANGA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 210
           
 Score =  123 bits (306), Expect = 2e-28
 Identities = 78/215 (36%), Positives = 116/215 (53%), Gaps = 24/215 (11%)

Query: 4   ISHITRNTKETQIELSINLDG-----------------TGQA-DISTGIGFLDHMLTLLT 45
           ++ + R T+ET I+L+++LDG                  GQ   + TG+GFLDHMLT L 
Sbjct: 1   MAFVKRVTQETNIQLALDLDGGSVSVRESILGKEYASGDGQTIHVHTGVGFLDHMLTALA 60

Query: 46  FHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEA 105
            H  + L +   GD   + +D HH +ED  IALG+   E LG+  GI+R+G    P+DEA
Sbjct: 61  KHGGWSLILECIGD---LHIDDHHTVEDCGIALGQAFKEALGSVRGIKRFGHGFAPLDEA 117

Query: 106 LVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTH 165
           L    +D S RP+ V    L   +++G   TEM   F  + A    IT+H++   G N H
Sbjct: 118 LSRAVVDFSNRPFAVVELGLK-RERIGQLSTEMIPHFLESFATEGRITMHVDCLRGTNDH 176

Query: 166 HIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           H  E  FK+ A A+++A +   +   ++PS+KGVL
Sbjct: 177 HRSESGFKALAIAIREART--PTGRDDVPSTKGVL 209


>gi|2506514|sp|P06633|HIS7_YEAST IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 220
           
 Score =  122 bits (304), Expect = 4e-28
 Identities = 79/218 (36%), Positives = 114/218 (52%), Gaps = 30/218 (13%)

Query: 7   ITRNTKETQIELSINLDGTGQA------------------------DISTGIGFLDHMLT 42
           + R T ET+I+++I+L G   A                        ++ TGIGFLDHM+ 
Sbjct: 8   VKRITNETKIQIAISLKGGPLAIEHSIFPEKEAEAVAEQATQSQVINVHTGIGFLDHMIH 67

Query: 43  LLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPM 102
            L  HS + L +   GD   + +D HH  ED  IALG+   E LG   G++R+GS   P+
Sbjct: 68  ALAKHSGWSLIVECIGD---LHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFAPL 124

Query: 103 DEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQ 162
           DEAL    +D+S RPY V    L   +K+G    EM   F  + A  + ITLH++   G+
Sbjct: 125 DEALSRAVVDLSNRPYAVVELGLQ-REKVGDLSCEMIPHFLESFAEASRITLHVDCLRGK 183

Query: 163 NTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           N HH  E  FK+ A A+++A S   +   ++PS+KGVL
Sbjct: 184 NDHHRSESAFKALAVAIREATS--PNGTNDVPSTKGVL 219


>gi|462274|sp|P34041|HIS7_TRIHA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 208
           
 Score =  106 bits (263), Expect = 3e-23
 Identities = 68/202 (33%), Positives = 102/202 (49%), Gaps = 28/202 (13%)

Query: 3   RISHITRNTKETQIELSINLDG------------------------TGQADISTGIGFLD 38
           R + ++R+T ET I++++++DG                        +    I+TGIGFLD
Sbjct: 8   RAAALSRDTNETSIQIALSIDGGELPQDADPRLLEASSAHASQTSKSQVISINTGIGFLD 67

Query: 39  HMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSF 98
           HML  L  H+ + + +   GD   + +D HH  ED  IA+G   ++ LG   G+ R+G  
Sbjct: 68  HMLHALAKHAGWSMALNCKGD---LHIDDHHTAEDCCIAVGTTFAKALGALTGVARFGYA 124

Query: 99  TIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNE 158
             P+DEAL    +D+S RPY V    L   +KLG    EM     ++ A  A ITLH++ 
Sbjct: 125 YAPLDEALSRAVVDLSNRPYTVVDLGLK-REKLGELSCEMIPHCLQSFAQAARITLHVDC 183

Query: 159 HYGQNTHHIIEGMFKSTARALK 180
             G N HH  E  FK+ A A++
Sbjct: 184 LRGDNDHHRAESAFKALAVAVR 205


>gi|1345641|sp|P49264|C7B1_THLAR CYTOCHROME P450 71B1 (CYPLXXIB1)
           Length = 496
           
 Score = 34.8 bits (78), Expect = 0.13
 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 11/134 (8%)

Query: 58  GDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRP 117
           G+   +G  PH  + +++   G  +S  LG+   +      T+   + L T DL+   RP
Sbjct: 40  GNLHQLGEKPHRAMVELSKTYGPLMSLKLGSVTTVVATSVETVR--DVLKTYDLECCSRP 97

Query: 118 YLVFHADLSGNQK---LGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKS 174
           Y+ + A ++ N K      YD     +++R +     + L+  +   Q+  HI E    S
Sbjct: 98  YMTYPARITYNLKDLVFSPYD-----KYWRQVRKLTVVELYTAKRV-QSFRHIREEEVAS 151

Query: 175 TARALKQAVSIDES 188
             R  KQA S +E+
Sbjct: 152 FVRFNKQAASSEET 165


>gi|1731346|sp|Q10698|YY29_MYCTU PROBABLE DIPEPTIDASE CY49.29C
           Length = 375
           
 Score = 31.7 bits (70), Expect = 1.1
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 3/45 (6%)

Query: 47  HSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLG 91
           HS+    I+G G H   G DPHH   D  +  G  +  D+G   G
Sbjct: 195 HSEVAFVIVGSGPH---GADPHHGYSDRELREGDIVVVDIGGTYG 236


>gi|3287839|sp|Q01812|GLK4_RAT GLUTAMATE RECEPTOR, IONOTROPIC
           KAINATE 4 PRECURSOR (GLUTAMATE RECEPTOR KA-1) (KA1)
           Length = 956
           
 Score = 30.1 bits (66), Expect = 3.3
 Identities = 17/48 (35%), Positives = 24/48 (49%), Gaps = 3/48 (6%)

Query: 117 PYLVF---HADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYG 161
           PYL+    H D+ GN +  G+  +M +E    L FN  I L  +  YG
Sbjct: 427 PYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 474


>gi|3123025|sp|Q94637|VIT6_OSCBR VITELLOGENIN 6 PRECURSOR
            Length = 1660
            
 Score = 29.3 bits (64), Expect = 5.6
 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 79   GKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLG---GYD 135
            GK ISED     GI + G     +D   VT + D  G    +  + L  N++ G    YD
Sbjct: 1436 GKEISEDKWEDFGISQRGEEKFFIDAEKVTVEFD--GFQAKIQMSSLYKNKQCGLCGHYD 1493

Query: 136  TEMTEEFFRA 145
             E T EF RA
Sbjct: 1494 GEKTNEFRRA 1503


>gi|1174406|sp|P36126|SP14_YEAST PHOSPHOLIPASE D1 (PLD 1) (CHOLINE
            PHOSPHATASE 1) (PHOSPHATIDYLCHOLINE-HYDROLYZING
            PHOSPHOLIPASE D1) (MEIOSIS-SPECIFIC SPORULATION PROTEIN
            SPO14)
            Length = 1380
            
 Score = 28.6 bits (62), Expect = 9.7
 Identities = 20/65 (30%), Positives = 31/65 (46%), Gaps = 7/65 (10%)

Query: 94   RYGSFTIPMDEAL-----VTCDLDISGRPYLVFHADLSGNQKL--GGYDTEMTEEFFRAL 146
            R GS ++P++E          D DI G  Y   H D+  NQ+L  G  D  +++   +  
Sbjct: 1141 RNGSNSLPLNEKSNEGESTNVDQDIEGDEYHRLHEDILKNQELDDGSLDDLLSQIIPKIT 1200

Query: 147  AFNAG 151
             FN+G
Sbjct: 1201 NFNSG 1205


>gi|3287848|sp|Q16099|GLK4_HUMAN GLUTAMATE RECEPTOR, IONOTROPIC
           KAINATE 4 PRECURSOR (GLUTAMATE RECEPTOR KA-1) (KA1)
           (EXCITATORY AMINO ACID RECEPTOR 1) (EAA1)
           Length = 956
           
 Score = 28.6 bits (62), Expect = 9.7
 Identities = 16/48 (33%), Positives = 24/48 (49%), Gaps = 3/48 (6%)

Query: 117 PYLVF---HADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYG 161
           PYL+    H ++ GN +  G+  +M +E    L FN  I L  +  YG
Sbjct: 427 PYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 474


Searching..................................................done


Results from round 2


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value
Sequences used in model and found again:

gi|2495230|sp|Q43072|HIS7_PEA IMIDAZOLEGLYCEROL-PHOSPHATE DEHYD...   323  1e-88
gi|462273|sp|P34047|HIS7_ARATH IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   322  3e-88
gi|399896|sp|Q02134|HIS7_LACLA IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   318  4e-87
gi|1346293|sp|P48054|HIS7_SYNY3 IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   315  5e-86
gi|462272|sp|Q05068|HIS7_ANASP IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   313  1e-85
gi|462275|sp|P34048|HIS7_WHEAT IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   313  2e-85
gi|123161|sp|P16247|HIS7_STRCO IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   306  2e-83
gi|2506514|sp|P06633|HIS7_YEAST IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   304  6e-83
gi|2495227|sp|P56090|HIS7_CANAL IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   304  8e-83
gi|399897|sp|Q02986|HIS7_SACKL IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   304  1e-82
gi|2495228|sp|Q12578|HIS7_CANGA IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   303  2e-82
gi|123158|sp|P06987|HIS7_ECOLI HISTIDINE BIOSYNTHESIS BIFUNCTIO...   302  4e-82
gi|123157|sp|P18787|HIS7_AZOBR IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   301  9e-82
gi|729718|sp|P40919|HIS7_CRYNE IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   299  2e-81
gi|2495229|sp|Q92447|HIS7_PICPA IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   298  5e-81
gi|1170286|sp|P44327|HIS7_HAEIN HISTIDINE BIOSYNTHESIS BIFUNCTI...   292  3e-79
gi|123159|sp|P28624|HIS7_PHYPR IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   290  2e-78
gi|729719|sp|P40374|HIS7_SCHPO IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   290  2e-78
gi|123160|sp|P10368|HIS7_SALTY HISTIDINE BIOSYNTHESIS BIFUNCTIO...   287  1e-77
gi|2495224|sp|O06590|HIS7_MYCTU IMIDAZOLEGLYCEROL-PHOSPHATE DEH...   283  2e-76
gi|2495226|sp|Q50504|HIS7_METTH PROBABLE IMIDAZOLEGLYCEROL-PHOS...   274  6e-74
gi|2495225|sp|Q58109|HIS7_METJA PROBABLE IMIDAZOLEGLYCEROL-PHOS...   271  1e-72
gi|462274|sp|P34041|HIS7_TRIHA IMIDAZOLEGLYCEROL-PHOSPHATE DEHY...   269  4e-72
gi|3334215|sp|O33773|HIS7_SULSO PROBABLE IMIDAZOLEGLYCEROL-PHOS...   262  5e-70

Sequences not found previously or not previously below threshold:

gi|2833252|sp|Q14571|IP3S_HUMAN INOSITOL 1,4,5-TRISPHOSPHATE-BI...    30  3.7
gi|266389|sp|P29995|IP3S_RAT INOSITOL 1,4,5-TRISPHOSPHATE-BINDI...    29  8.2


CONVERGED!
>gi|2495230|sp|Q43072|HIS7_PEA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 281
           
 Score =  323 bits (820), Expect = 1e-88
 Identities = 96/199 (48%), Positives = 136/199 (68%), Gaps = 4/199 (2%)

Query: 2   TRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHE 61
           TR+  + R TKET + + INLDG+G AD STGI FLDHML  L  H  FD+ +   GD  
Sbjct: 84  TRVGEVKRVTKETNVSVKINLDGSGVADSSTGIPFLDHMLDQLASHGLFDVHVKATGD-- 141

Query: 62  TVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVF 121
            V +D HH  EDVA+A+G  + + LG++ GI R+G F+ P+DEAL+   LD+SGRP+L +
Sbjct: 142 -VHIDDHHTNEDVALAIGTALLQALGDRKGINRFGDFSAPLDEALIHVSLDLSGRPHLSY 200

Query: 122 HADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQ 181
           + D+   Q++G YDT++ E F +++   +G+TLH+ +  G+N+HHIIE  FK+ ARAL+Q
Sbjct: 201 NLDIP-TQRVGTYDTQVVEHFLQSIVNTSGMTLHIRQLAGRNSHHIIEATFKAFARALRQ 259

Query: 182 AVSIDESKVGEIPSSKGVL 200
           A   D  + G +PSSKGVL
Sbjct: 260 ATEYDPRRRGSVPSSKGVL 278


>gi|462273|sp|P34047|HIS7_ARATH IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 270
           
 Score =  322 bits (817), Expect = 3e-88
 Identities = 99/198 (50%), Positives = 135/198 (68%), Gaps = 4/198 (2%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           RI  + R TKET + + INLDGTG AD S+GI FLDHML  L  H  FD+ +   GD   
Sbjct: 74  RIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFDVHVRATGD--- 130

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           V +D HH  ED+A+A+G  + + LG + GI R+G FT P+DEAL+   LD+SGRPYL ++
Sbjct: 131 VHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYN 190

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
            ++   Q++G YDT++ E FF++L   +G+TLH+ +  G+N+HHIIE  FK+ ARAL+QA
Sbjct: 191 LEIP-TQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGENSHHIIEATFKAFARALRQA 249

Query: 183 VSIDESKVGEIPSSKGVL 200
              D  + G IPSSKGVL
Sbjct: 250 TETDPRRGGTIPSSKGVL 267


>gi|399896|sp|Q02134|HIS7_LACLA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 200
           
 Score =  318 bits (808), Expect = 4e-87
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60
           MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH
Sbjct: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60

Query: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120
           ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV
Sbjct: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120

Query: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180
           FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK
Sbjct: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180

Query: 181 QAVSIDESKVGEIPSSKGVL 200
           QAVSIDESKVGEIPSSKGVL
Sbjct: 181 QAVSIDESKVGEIPSSKGVL 200


>gi|1346293|sp|P48054|HIS7_SYNY3 IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 210
           
 Score =  315 bits (798), Expect = 5e-86
 Identities = 88/198 (44%), Positives = 129/198 (64%), Gaps = 4/198 (2%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R + + R TKET + +S+NL G+G   ++TG+ FLDHML  +  H   DL++   GD E 
Sbjct: 17  RAAAVHRVTKETDVRVSLNLMGSGLCHVATGVPFLDHMLHQIASHGLIDLEVNATGDIE- 75

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH  EDV I LG+ ++E LG++ GI R+G F  P+DEALV   LD SGRP+L + 
Sbjct: 76  --IDDHHTNEDVGITLGQALAEALGDRRGINRFGHFIAPLDEALVQVTLDFSGRPHLSYG 133

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
             +   +++G YDT++  EFF A+  ++ +TLH+ +  G N+HHIIE  FK+ ARA++ A
Sbjct: 134 LQIP-TERVGTYDTQLVREFFVAVVNHSQMTLHIRQLDGINSHHIIEATFKAFARAMRMA 192

Query: 183 VSIDESKVGEIPSSKGVL 200
           + +D  +   IPSSKGVL
Sbjct: 193 IEVDPRRADTIPSSKGVL 210


>gi|462272|sp|Q05068|HIS7_ANASP IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 209
           
 Score =  313 bits (795), Expect = 1e-85
 Identities = 91/198 (45%), Positives = 131/198 (65%), Gaps = 4/198 (2%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           RI+ + R T ET +++++NLDGTG    +TGI FLDHML  ++ H   DL +   GD E 
Sbjct: 16  RIASVHRITGETNVQVTVNLDGTGICKAATGIPFLDHMLHQISSHGLIDLDVQAKGDWE- 74

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH  EDV I LG+ +++ LG++ GI R+G+F  P+DEALV   LD SGRP+L + 
Sbjct: 75  --IDDHHTNEDVGITLGQALAKALGDRKGIVRFGNFLAPLDEALVQVALDFSGRPHLSYG 132

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
             +   +++G YDT++  EFF AL  ++ +TLH+ +  G N+HHIIE  FK+ ARA + A
Sbjct: 133 LQIP-TERVGTYDTQLVREFFVALVNHSQMTLHIRQLDGINSHHIIEATFKAFARAARMA 191

Query: 183 VSIDESKVGEIPSSKGVL 200
           + +D  + G IPSSKGVL
Sbjct: 192 IEVDPRRAGTIPSSKGVL 209


>gi|462275|sp|P34048|HIS7_WHEAT IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 195
           
 Score =  313 bits (793), Expect = 2e-85
 Identities = 93/196 (47%), Positives = 128/196 (64%), Gaps = 4/196 (2%)

Query: 5   SHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHETVG 64
             + R TKET + + INLDGTG A+ STGI FLDHML  L  H  FD+ +   GD     
Sbjct: 1   GEVKRVTKETNVHVKINLDGTGVANSSTGIPFLDHMLDQLASHGLFDVYVKATGDT---H 57

Query: 65  MDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFHAD 124
           +D HH  ED+A+A+G  + + LG++ GI R+G FT P+DEA V   LD+SGRP+L     
Sbjct: 58  IDDHHSNEDIALAIGTALLQALGDRKGINRFGHFTAPLDEAAVEVILDLSGRPHLSCGLS 117

Query: 125 LSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQAVS 184
           +   +++G YDT++ E FF++L   +G+TLH+ +  G N+HHIIE  FK+ ARAL+QA  
Sbjct: 118 IP-TERVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGNNSHHIIEATFKAFARALRQATE 176

Query: 185 IDESKVGEIPSSKGVL 200
            D  + G +PSSKGVL
Sbjct: 177 YDLRRQGTMPSSKGVL 192


>gi|123161|sp|P16247|HIS7_STRCO IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 197
           
 Score =  306 bits (776), Expect = 2e-83
 Identities = 89/200 (44%), Positives = 124/200 (61%), Gaps = 3/200 (1%)

Query: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60
           M+R+  + R TKET + + I+LDGTG+ DI+TG+GF DHML  L  H  FDL +   GD 
Sbjct: 1   MSRVGRVERTTKETSVLVEIDLDGTGKTDIATGVGFYDHMLDQLGRHGLFDLTVKTDGD- 59

Query: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120
             + +D HH IED A+ALG    + LG+K+GI R+G+ T+P+DE+L    +D+SGRPYLV
Sbjct: 60  --LHIDSHHTIEDTALALGAAFRQALGDKVGIYRFGNCTVPLDESLAQVTVDLSGRPYLV 117

Query: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180
                +    +G YD  MT     +    A + LH++  YG+N HHI+E  FK+ ARAL+
Sbjct: 118 HTEPENMAPMIGEYDVTMTRHILESFVAQAQVALHVHVPYGRNAHHIVECQFKALARALR 177

Query: 181 QAVSIDESKVGEIPSSKGVL 200
            A   D    G +PS+KG L
Sbjct: 178 YASERDPRAAGILPSTKGAL 197


>gi|2506514|sp|P06633|HIS7_YEAST IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 220
           
 Score =  304 bits (772), Expect = 6e-83
 Identities = 78/220 (35%), Positives = 115/220 (51%), Gaps = 30/220 (13%)

Query: 5   SHITRNTKETQIELSINLDG------------------------TGQADISTGIGFLDHM 40
           + + R T ET+I+++I+L G                        +   ++ TGIGFLDHM
Sbjct: 6   ALVKRITNETKIQIAISLKGGPLAIEHSIFPEKEAEAVAEQATQSQVINVHTGIGFLDHM 65

Query: 41  LTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTI 100
           +  L  HS + L +   GD   + +D HH  ED  IALG+   E LG   G++R+GS   
Sbjct: 66  IHALAKHSGWSLIVECIGD---LHIDDHHTTEDCGIALGQAFKEALGAVRGVKRFGSGFA 122

Query: 101 PMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHY 160
           P+DEAL    +D+S RPY V    L   +K+G    EM   F  + A  + ITLH++   
Sbjct: 123 PLDEALSRAVVDLSNRPYAVVELGL-QREKVGDLSCEMIPHFLESFAEASRITLHVDCLR 181

Query: 161 GQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           G+N HH  E  FK+ A A+++A S   +   ++PS+KGVL
Sbjct: 182 GKNDHHRSESAFKALAVAIREATS--PNGTNDVPSTKGVL 219


>gi|2495227|sp|P56090|HIS7_CANAL IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 223
           
 Score =  304 bits (771), Expect = 8e-83
 Identities = 81/227 (35%), Positives = 119/227 (51%), Gaps = 33/227 (14%)

Query: 1   MTRISHITRNTKETQIELSINLDG---------------------------TGQADISTG 33
           M+R + I R T ET+I++++NLDG                           +   ++ TG
Sbjct: 1   MSREALINRITNETKIQIALNLDGGKLELKESIFPNQSIIIDEHHAKQVSGSQYINVQTG 60

Query: 34  IGFLDHMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIR 93
           IGFLDHM+  L  HS + L +   GD   + +D HH  EDV I+LG    + LG   G++
Sbjct: 61  IGFLDHMIHALAKHSGWSLIVECIGD---LHIDDHHTAEDVGISLGMAFKQALGQIKGVK 117

Query: 94  RYGSFTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGIT 153
           R+G    P+DEAL    +D+S RP+ V    L   +K+G   TEM      + A   GIT
Sbjct: 118 RFGHGFAPLDEALSRAVVDLSNRPFAVIELGLK-REKIGDLSTEMIPHVLESFAGAVGIT 176

Query: 154 LHLNEHYGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           +H++   G N HH  E  FK+ A A+K+A+S  ++   +IPS+KGVL
Sbjct: 177 IHVDCLRGFNDHHRAESAFKALAIAIKEAIS--KTGKNDIPSTKGVL 221


>gi|399897|sp|Q02986|HIS7_SACKL IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 232
           
 Score =  304 bits (770), Expect = 1e-82
 Identities = 79/222 (35%), Positives = 118/222 (52%), Gaps = 30/222 (13%)

Query: 3   RISHITRNTKETQIELSINLDG------------------------TGQADISTGIGFLD 38
           R + I+R T ET+I+++I+L+G                        +   DI TG+GFLD
Sbjct: 16  RKAFISRITNETKIQIAISLNGGYIQIKDSILPAKKDDDVASQATQSQVIDIHTGVGFLD 75

Query: 39  HMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSF 98
           HM+  L  HS + L +   GD   + +D HH  ED  IALG+   E +G   G++R+G+ 
Sbjct: 76  HMIHALAKHSGWSLIVECIGD---LHIDDHHTTEDCGIALGQAFKEAMGAVRGVKRFGTG 132

Query: 99  TIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNE 158
             P+DEAL    +D+S RP+ V    L   + +G   TEM   F  + A  A ITLH++ 
Sbjct: 133 FAPLDEALSRAVVDLSNRPFAVIDLGLK-REMIGDLSTEMIPHFLESFAEAARITLHVDC 191

Query: 159 HYGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
             G N HH  E  FK+ A A+++A+S   +   ++PS+KGVL
Sbjct: 192 LRGFNDHHRSESAFKALAVAIREAIS--SNGTNDVPSTKGVL 231


>gi|2495228|sp|Q12578|HIS7_CANGA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 210
           
 Score =  303 bits (767), Expect = 2e-82
 Identities = 76/214 (35%), Positives = 113/214 (52%), Gaps = 24/214 (11%)

Query: 5   SHITRNTKETQIELSINLDGTGQA------------------DISTGIGFLDHMLTLLTF 46
           + + R T+ET I+L+++LDG   +                   + TG+GFLDHMLT L  
Sbjct: 2   AFVKRVTQETNIQLALDLDGGSVSVRESILGKEYASGDGQTIHVHTGVGFLDHMLTALAK 61

Query: 47  HSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEAL 106
           H  + L +   GD   + +D HH +ED  IALG+   E LG+  GI+R+G    P+DEAL
Sbjct: 62  HGGWSLILECIGD---LHIDDHHTVEDCGIALGQAFKEALGSVRGIKRFGHGFAPLDEAL 118

Query: 107 VTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHH 166
               +D S RP+ V    L   +++G   TEM   F  + A    IT+H++   G N HH
Sbjct: 119 SRAVVDFSNRPFAVVELGLK-RERIGQLSTEMIPHFLESFATEGRITMHVDCLRGTNDHH 177

Query: 167 IIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
             E  FK+ A A+++A     +   ++PS+KGVL
Sbjct: 178 RSESGFKALAIAIREA--RTPTGRDDVPSTKGVL 209


>gi|123158|sp|P06987|HIS7_ECOLI HISTIDINE BIOSYNTHESIS BIFUNCTIONAL
           PROTEIN HISB [INCLUDES: IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD); HISTIDINOL-PHOSPHATASE ]
           Length = 355
           
 Score =  302 bits (765), Expect = 4e-82
 Identities = 91/198 (45%), Positives = 130/198 (64%), Gaps = 9/198 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R +H+ RNTKETQI++ + LD  G + I+TG+GF DHML  +  H  F ++I   GD   
Sbjct: 167 RYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGD--- 223

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           + +D HH +ED  +ALG+ +   LG+K GI R+G F +PMDE L  C LDISGRP+L + 
Sbjct: 224 LYIDDHHTVEDTGLALGEALKIALGDKRGICRFG-FVLPMDECLARCALDISGRPHLEYK 282

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
           A+ +  Q++G   TEM E FFR+L++  G+TLHL    G+N HH +E +FK+  R L+QA
Sbjct: 283 AEFT-YQRVGDLSTEMIEHFFRSLSYTMGVTLHLKT-KGKNDHHRVESLFKAFGRTLRQA 340

Query: 183 VSIDESKVGEIPSSKGVL 200
           + ++      +PSSKGVL
Sbjct: 341 IRVEG---DTLPSSKGVL 355


>gi|123157|sp|P18787|HIS7_AZOBR IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 207
           
 Score =  301 bits (762), Expect = 9e-82
 Identities = 91/196 (46%), Positives = 127/196 (64%), Gaps = 4/196 (2%)

Query: 5   SHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHETVG 64
           + I RNT ET+I +++NLDGTG  D+ TG+GFLDHML  L+ HS  DL +   GD   V 
Sbjct: 12  ASIERNTTETRIRVAVNLDGTGVYDVKTGVGFLDHMLEQLSRHSLMDLSVAAEGD---VH 68

Query: 65  MDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFHAD 124
           +D HH  E   IA+G+ +++ +G++ GI+RYG   +PMDE L    LD S RPYL++   
Sbjct: 69  IDAHHTTEHSGIAIGQAVAKAVGDRKGIQRYGHAYVPMDETLTRVALDFSNRPYLIWKVS 128

Query: 125 LSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQAVS 184
            S   K+G  DTE+  E+F+A A  AG+TLH+   YG+N HHI+E  +K+ ARAL+  + 
Sbjct: 129 FS-RDKIGDMDTELFREWFQAFAMAAGVTLHVECLYGENNHHIVESCYKALARALRAGIE 187

Query: 185 IDESKVGEIPSSKGVL 200
           ID  K   +PS+KG L
Sbjct: 188 IDPRKRDAVPSTKGTL 203


>gi|729718|sp|P40919|HIS7_CRYNE IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 202
           
 Score =  299 bits (759), Expect = 2e-81
 Identities = 83/203 (40%), Positives = 120/203 (58%), Gaps = 11/203 (5%)

Query: 3   RISHITRNTKETQIELSINLDG-----TGQADISTGIGFLDHMLTLLTFHSDFDLKIIGH 57
           RI+ + R T ET I  +I+LD        + ++STGIGFLDHM T L  H    L++   
Sbjct: 4   RIASVERTTSETHISCTIDLDHIPGVTEQKINVSTGIGFLDHMFTALAKHGGMSLQLQCK 63

Query: 58  GDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRP 117
           GD   + +D HH  ED A+ALG+   + LG + GI+RYG    P+DE+L    +DIS RP
Sbjct: 64  GD---LHIDDHHTAEDCALALGEAFKKALGERKGIKRYGYAYAPLDESLSRAVIDISSRP 120

Query: 118 YLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTAR 177
           Y + H   +  +K+G   TEM     ++ AF AG+TLH++   G+N HHI E  FK+ A 
Sbjct: 121 YFMCHLPFT-REKVGDLSTEMVSHLLQSFAFAAGVTLHIDSIRGENNHHIAESAFKALAL 179

Query: 178 ALKQAVSIDESKVGEIPSSKGVL 200
           A++ A+S   +   ++PS+KGVL
Sbjct: 180 AIRMAIS--RTGGDDVPSTKGVL 200


>gi|2495229|sp|Q92447|HIS7_PICPA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 224
           
 Score =  298 bits (756), Expect = 5e-81
 Identities = 82/223 (36%), Positives = 115/223 (50%), Gaps = 31/223 (13%)

Query: 3   RISHITRNTKETQIELSINLDGTGQA-------------------------DISTGIGFL 37
           R S I R T ET+I+++++LDG   +                          ++TGIGFL
Sbjct: 7   RSSLIKRITNETKIQIALSLDGGPVSLAQSLFKDKDYSAEHAAQATSSQFISVNTGIGFL 66

Query: 38  DHMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGS 97
           DHML  L  H  + + I   GD   + +D HH  ED  IALG    E LG+  GI+R+GS
Sbjct: 67  DHMLHALAKHGGWSVIIECVGD---LHIDDHHSAEDTGIALGMAFKEALGHVRGIKRFGS 123

Query: 98  FTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLN 157
              P+DEAL    +D+S RPY V    L   +K+G    EM      + A  A +T+H++
Sbjct: 124 GFAPLDEALSRAVIDMSNRPYAVVDLGLK-REKIGDLSCEMIPHVLESFAQGAHVTMHVD 182

Query: 158 EHYGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
              G N HH  E  FK+ A A+K+A+S   +   +IPS+KGVL
Sbjct: 183 CLRGFNDHHRAESAFKALAIAIKEAIS--SNGTDDIPSTKGVL 223


>gi|1170286|sp|P44327|HIS7_HAEIN HISTIDINE BIOSYNTHESIS BIFUNCTIONAL
           PROTEIN HISB [INCLUDES: IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD); HISTIDINOL-PHOSPHATASE ]
           Length = 362
           
 Score =  292 bits (741), Expect = 3e-79
 Identities = 89/198 (44%), Positives = 127/198 (63%), Gaps = 9/198 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R + + R TKET I++ + LD  G  +I TG+GF DHML  +  H  F + +   GD   
Sbjct: 174 RFAEVIRQTKETDIKVQVWLDEAGVNEIKTGVGFFDHMLDQIATHGGFRMNVQCKGD--- 230

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           + +D HH +ED A+ALG+ + + +G+K GI R+G F +PMDE    C LD+SGRP++ F+
Sbjct: 231 LWIDEHHTVEDTALALGQALKQAVGDKRGIARFG-FVLPMDECKAECALDLSGRPWIKFN 289

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
           A      K+G + TE+TE FF++LAF+   TLHLN   G N HH IE +FK+  R L+QA
Sbjct: 290 ACFK-RDKVGDFSTELTEHFFQSLAFSMLATLHLNV-TGNNDHHKIESLFKAFGRTLRQA 347

Query: 183 VSIDESKVGEIPSSKGVL 200
           + I+ +   E+PSSKGVL
Sbjct: 348 IRIEGN---EMPSSKGVL 362


>gi|123159|sp|P28624|HIS7_PHYPR IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 452
           
 Score =  290 bits (734), Expect = 2e-78
 Identities = 86/199 (43%), Positives = 121/199 (60%), Gaps = 8/199 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R ++I+R TKET I + ++LDGTG++ +S+GIGFLDHMLT L  HS FDL++   GD   
Sbjct: 260 REANISRVTKETSISVKLSLDGTGKSKVSSGIGFLDHMLTALAKHSRFDLELDCKGDT-- 317

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH  ED A+ LG+     LG++ GI R+GS  +P+DEAL    +DIS R +   +
Sbjct: 318 -WIDDHHTTEDCALTLGEAFDVALGDRAGIARFGSACVPLDEALSRAIVDISSRAHSEIN 376

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGI-TLHLNEHYGQNTHHIIEGMFKSTARALKQ 181
             L     +G   +EM   FF + A  A + TLH++   G+N HH  E  FK+ A AL+ 
Sbjct: 377 LQLV-RPSVGELSSEMITHFFESFASAA-LXTLHVDVLRGRNDHHRAEASFKALAVALRT 434

Query: 182 AVSIDESKVGEIPSSKGVL 200
           AV  D +    +PS+KGVL
Sbjct: 435 AVKHDAT--AGVPSTKGVL 451


>gi|729719|sp|P40374|HIS7_SCHPO IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 216
           
 Score =  290 bits (734), Expect = 2e-78
 Identities = 83/221 (37%), Positives = 114/221 (51%), Gaps = 29/221 (13%)

Query: 3   RISHITRNTKETQIELSINLD-----------------------GTGQADISTGIGFLDH 39
           R + + RNT ET+I ++I LD                       G     + TGIGFLDH
Sbjct: 2   RRAFVERNTNETKISVAIALDKAPLPEESNFIDELITSKHANQKGEQVIQVDTGIGFLDH 61

Query: 40  MLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFT 99
           M   L  H+ + L++   GD   + +D HH  ED AIALG    + +GN  G++R+G   
Sbjct: 62  MYHALAKHAGWSLRLYSRGD---LIIDDHHTAEDTAIALGIAFKQAMGNFAGVKRFGHAY 118

Query: 100 IPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEH 159
            P+DEAL    +D+SGRPY V    L   +K+G    EM      + +  AGITLH+   
Sbjct: 119 CPLDEALSRSVVDLSGRPYAVIDLGLK-REKVGELSCEMIPHLLYSFSVAAGITLHVTCL 177

Query: 160 YGQNTHHIIEGMFKSTARALKQAVSIDESKVGEIPSSKGVL 200
           YG N HH  E  FKS A A++ A S+  +   E+PS+KGVL
Sbjct: 178 YGSNDHHRAESAFKSLAVAMRAATSL--TGSSEVPSTKGVL 216


>gi|123160|sp|P10368|HIS7_SALTY HISTIDINE BIOSYNTHESIS BIFUNCTIONAL
           PROTEIN HISB [INCLUDES: IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD); HISTIDINOL-PHOSPHATASE ]
           Length = 354
           
 Score =  287 bits (726), Expect = 1e-77
 Identities = 89/198 (44%), Positives = 129/198 (64%), Gaps = 10/198 (5%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R +H+ RNTKETQI++S+ LD  G + I+TG+GF DHML  +  H  F ++I   GD   
Sbjct: 167 RYAHVVRNTKETQIDVSVWLDREGNSKINTGVGFFDHMLDQIATHGGFRMEITVKGD--- 223

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
           + +D HH +ED  +AL + +   L +K GI R+G F +PMDE L  C LDISGRP+L + 
Sbjct: 224 LYIDDHHTVEDTGLALREALKLALRDKRGICRFG-FVLPMDECLA-CALDISGRPHLEYK 281

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
           A+ +  Q++G   TEM E FFR+L++  G+TLHL    G+N HH +E +FK+  R ++QA
Sbjct: 282 AEFT-YQRVGNLSTEMIEHFFRSLSYTMGVTLHLKT-KGKNDHHRVESLFKAFGRTVRQA 339

Query: 183 VSIDESKVGEIPSSKGVL 200
           + ++      +PSSKGVL
Sbjct: 340 IRVEG---DTLPSSKGVL 354


>gi|2495224|sp|O06590|HIS7_MYCTU IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 210
           
 Score =  283 bits (716), Expect = 2e-76
 Identities = 92/207 (44%), Positives = 124/207 (59%), Gaps = 14/207 (6%)

Query: 2   TRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHE 61
           +R + I R T+E+ I + ++LDGTGQ  + TG+ F DHMLT L  H+ FDL +   GD E
Sbjct: 10  SRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVE 69

Query: 62  TVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVF 121
              ++ HH IED AIALG  + + LG+K GIRR+G   IPMDE L    +D+SGRPY V 
Sbjct: 70  ---IEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVH 126

Query: 122 --------HADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFK 173
                   H  ++G+     Y T +    F +LA NA I LH+   YG++ HHI E  +K
Sbjct: 127 TGEPDHLQHTTIAGSSV--PYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYK 184

Query: 174 STARALKQAVSIDESKVGEIPSSKGVL 200
           + ARAL+QAV  D   V  +PS+KG L
Sbjct: 185 AVARALRQAVEPDPR-VSGVPSTKGAL 210


>gi|2495226|sp|Q50504|HIS7_METTH PROBABLE
           IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD)
           Length = 194
           
 Score =  274 bits (695), Expect = 6e-74
 Identities = 81/198 (40%), Positives = 122/198 (60%), Gaps = 8/198 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           R S  TR T ET +++ + +DG+G++ ++TG+GFLDHML  +  H   DL++   GD E 
Sbjct: 5   RRSMKTRETLETHVKVDLEIDGSGKSSVNTGLGFLDHMLESVARHGLLDLEVEARGDLE- 63

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH +EDVA+ LG+ + E LG+K GIRR     +PMD+AL T  LD+SGRPY V  
Sbjct: 64  --VDDHHTVEDVALTLGEALREALGDKSGIRRMAHAMVPMDDALATVALDLSGRPYTVLE 121

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
            +   +  +G   ++    F  +LA +A + +H +   G+N HH  E +FK+ A A++ A
Sbjct: 122 LEFD-DAVIGDVKSQNIGHFIESLAVSAAMNIHASV-RGRNDHHKAEALFKALALAIRDA 179

Query: 183 VSIDESKVGEIPSSKGVL 200
           V ++    GEIPS+KG L
Sbjct: 180 VRVEH---GEIPSTKGKL 194


>gi|2495225|sp|Q58109|HIS7_METJA PROBABLE
           IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD)
           Length = 197
           
 Score =  271 bits (685), Expect = 1e-72
 Identities = 79/196 (40%), Positives = 106/196 (53%), Gaps = 9/196 (4%)

Query: 3   RISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDHET 62
           RI  + R TKET I L IN+DGTG+  I TGI F DH+L     H  FDL +   GD E 
Sbjct: 7   RIFEVMRETKETNIYLKINIDGTGKYKIDTGIPFFDHLLASFAKHGCFDLIVKARGDLE- 65

Query: 63  VGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLVFH 122
             +D HH +EDV I LG  +++    K  I R+G   IPMD+A  T  +D+SGR Y V +
Sbjct: 66  --IDDHHTVEDVGICLGLALNQI--EKRNIFRFGWAIIPMDDARATVAIDLSGRSYCVGN 121

Query: 123 ADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALKQA 182
            +    + +G   TE    FF ++A    + +H     G+N HH  E +FK+   AL  A
Sbjct: 122 YE-PKREFVGDLATENINHFFESVASYGMLNIHYEVI-GKNEHHKAEALFKAFGVALDLA 179

Query: 183 VSIDESKVGEIPSSKG 198
             IDE K   + S+KG
Sbjct: 180 TKIDERK--GVISTKG 193


>gi|462274|sp|P34041|HIS7_TRIHA IMIDAZOLEGLYCEROL-PHOSPHATE
           DEHYDRATASE (IGPD)
           Length = 208
           
 Score =  269 bits (680), Expect = 4e-72
 Identities = 68/202 (33%), Positives = 102/202 (49%), Gaps = 28/202 (13%)

Query: 3   RISHITRNTKETQIELSINLDG------------------------TGQADISTGIGFLD 38
           R + ++R+T ET I++++++DG                        +    I+TGIGFLD
Sbjct: 8   RAAALSRDTNETSIQIALSIDGGELPQDADPRLLEASSAHASQTSKSQVISINTGIGFLD 67

Query: 39  HMLTLLTFHSDFDLKIIGHGDHETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSF 98
           HML  L  H+ + + +   GD   + +D HH  ED  IA+G   ++ LG   G+ R+G  
Sbjct: 68  HMLHALAKHAGWSMALNCKGD---LHIDDHHTAEDCCIAVGTTFAKALGALTGVARFGYA 124

Query: 99  TIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNE 158
             P+DEAL    +D+S RPY V    L   +KLG    EM     ++ A  A ITLH++ 
Sbjct: 125 YAPLDEALSRAVVDLSNRPYTVVDLGLK-REKLGELSCEMIPHCLQSFAQAARITLHVDC 183

Query: 159 HYGQNTHHIIEGMFKSTARALK 180
             G N HH  E  FK+ A A++
Sbjct: 184 LRGDNDHHRAESAFKALAVAVR 205


>gi|3334215|sp|O33773|HIS7_SULSO PROBABLE
           IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (IGPD)
           Length = 193
           
 Score =  262 bits (662), Expect = 5e-70
 Identities = 83/200 (41%), Positives = 124/200 (61%), Gaps = 7/200 (3%)

Query: 1   MTRISHITRNTKETQIELSINLDGTGQADISTGIGFLDHMLTLLTFHSDFDLKIIGHGDH 60
           M+R ++ITR TKET+IE+ +++D  G+  +ST I F +HML  L  + +    +      
Sbjct: 1   MSRSANITRETKETKIEVLLDIDRKGEVKVSTPIPFFNHMLITLLTYMNSTAIVSAT--- 57

Query: 61  ETVGMDPHHLIEDVAIALGKCISEDLGNKLGIRRYGSFTIPMDEALVTCDLDISGRPYLV 120
           + +  D HH++EDVAI LG  I   LG+K GI+R+    IPMD+ALV   LDIS R    
Sbjct: 58  DKLPYDDHHIVEDVAITLGLAIKTALGDKRGIKRFSHQIIPMDDALVLVSLDISNRGMAF 117

Query: 121 FHADLSGNQKLGGYDTEMTEEFFRALAFNAGITLHLNEHYGQNTHHIIEGMFKSTARALK 180
            + +L  ++ +GG  TE    FF++ A+N+GITLH+++  G NTHHIIE  FK+   AL 
Sbjct: 118 VNLNLKRSE-IGGLATENVPHFFQSFAYNSGITLHISQLSGYNTHHIIEASFKALGLALY 176

Query: 181 QAVSIDESKVGEIPSSKGVL 200
           +A  I ++   EI S+KG++
Sbjct: 177 EATRIVDN---EIRSTKGII 193


>gi|2833252|sp|Q14571|IP3S_HUMAN INOSITOL 1,4,5-TRISPHOSPHATE-BINDING
            PROTEIN TYPE 2 RECEPTOR (TYPE 2 INSP3 RECEPTOR) (TYPE 2
            INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR)
            Length = 2701
            
 Score = 30.0 bits (66), Expect = 3.7
 Identities = 18/120 (15%), Positives = 39/120 (32%), Gaps = 19/120 (15%)

Query: 41   LTLLTFHSDFDLKIIGHGDHETVGMDPH-HLIEDVAIAL------GKCISEDLG----NK 89
            L  +  +    + +       T+ M  H ++++  A+        G    E LG    + 
Sbjct: 1540 LAEVAKNRGIAIPVDLDSQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKEALGGPAWDY 1599

Query: 90   LGI--------RRYGSFTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEE 141
              I                PM +A  +  +D+   P L+F        + G + +++   
Sbjct: 1600 RNIIEKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINH 1659


>gi|266389|sp|P29995|IP3S_RAT INOSITOL 1,4,5-TRISPHOSPHATE-BINDING
            PROTEIN TYPE 2 RECEPTOR (TYPE 2 INSP3 RECEPTOR) (TYPE 2
            INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR)
            Length = 2701
            
 Score = 28.8 bits (63), Expect = 8.2
 Identities = 18/120 (15%), Positives = 37/120 (30%), Gaps = 19/120 (15%)

Query: 41   LTLLTFHSDFDLKIIGHGDHETVGMDPHH-LIEDVAIAL------GKCISEDLG----NK 89
            L  +  +    + +       T+ M  H   ++  A+        G    E LG    + 
Sbjct: 1540 LAEVAKNRGIAIPVDLDSQVNTLFMKNHSSTVQRAAMGWRLSARSGPRFKEALGGPAWDY 1599

Query: 90   LGI--------RRYGSFTIPMDEALVTCDLDISGRPYLVFHADLSGNQKLGGYDTEMTEE 141
              I                PM +A  +  +D+   P L+F        + G + +++   
Sbjct: 1600 RNIIEKLQDVVASLEQQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINH 1659


  Database: data/swissprot
    Posted date:  Feb 2, 2000  9:39 AM
  Number of letters in database: 29,652,561
  Number of sequences in database:  82,258
  
Lambda     K      H
   0.317    0.149    0.479 

Lambda     K      H
   0.270   0.0524    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26734132
Number of Sequences: 82258
Number of extensions: 1229035
Number of successful extensions: 2616
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2403
Number of HSP's gapped (non-prelim): 58
length of query: 200
length of database: 29,652,561
effective HSP length: 50
effective length of query: 150
effective length of database: 25,539,661
effective search space: 3830949150
effective search space used: 3830949150
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.5 bits)
S2: 63 (28.8 bits)