1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
|
Query sp|Q9BSU1|CP070_HUMAN UPF0183 protein C16orf70 OS=Homo sapiens OX=9606 GN=C16orf70 PE=1 SV=1
Match_columns 422
No_of_seqs 157 out of 584
Neff 6.82639
Searched_HMMs 64707
Date Fri Feb 1 15:48:30 2019
Command hhsearch -cpu 8 -i ../results/full.a3m -d /cluster/toolkit/production/databases/hh-suite/mmcif70/pdb70 -d /cluster/toolkit/production/databases/hh-suite/pfama/pfama -o ../results/9590198.hhr -oa3m ../results/9590198.a3m -p 20 -Z 250 -loc -z 1 -b 1 -B 250 -ssm 2 -sc 1 -seq 1 -dbstrlen 10000 -norealign -maxres 32000 -contxt /cluster/toolkit/production/bioprogs/tools/hh-suite-build/data/context_data.crf
No Hit Prob E-value P-value Score SS Cols Query HMM Template HMM
1 PF03676.14 ; UPF0183 ; Unchara 100.0 1E-101 2E-106 792.8 45.5 376 22-407 1-394 (394)
2 PF12978.7 ; DUF3862 ; Domain o 71.8 67 0.001 28.6 9.5 127 239-409 12-159 (159)
3 PF04355.13 ; SmpA_OmlA ; SmpA 70.2 4.9 7.6E-05 30.4 1.6 20 239-258 12-31 (73)
4 5EKQ_E Outer membrane protein 68.1 5.9 9.1E-05 32.0 1.7 20 239-258 27-46 (94)
5 PF11399.8 ; DUF3192 ; Protein 58.7 13 0.0002 30.7 1.9 20 239-258 34-53 (104)
6 5WAM_B Outer membrane protein 58.5 11 0.00017 31.4 1.6 20 239-258 30-49 (108)
7 3GMX_B BLP; 2-layer alpha/beta 57.7 1.6E+02 0.0025 26.1 9.0 109 19-139 12-141 (154)
8 PF14504.6 ; CAP_assoc_N ; CAP- 57.1 24 0.00037 30.6 3.4 70 239-312 62-131 (140)
9 2YH9_C SMALL PROTEIN A; LIPOPR 56.4 14 0.00021 30.0 1.6 20 239-258 13-32 (88)
10 PF14504.6 ; CAP_assoc_N ; CAP- 56.2 30 0.00046 30.0 3.9 54 241-312 1-55 (140)
11 4DM5_A Osmotically inducible l 56.2 14 0.00021 31.5 1.7 20 239-258 24-43 (103)
12 PF14504.6 ; CAP_assoc_N ; CAP- 56.1 77 0.0012 27.4 6.5 65 13-83 61-130 (140)
13 PF14172.6 ; DUF4309 ; Domain o 53.8 2.4E+02 0.0037 24.8 11.3 119 9-174 11-135 (135)
14 PF07467.11 ; BLIP ; Beta-lacta 52.9 16 0.00025 31.4 1.6 20 239-258 8-27 (121)
15 PF11006.8 ; DUF2845 ; Protein 50.9 27 0.00041 28.6 2.5 27 239-265 11-37 (94)
16 PF12978.7 ; DUF3862 ; Domain o 49.4 1.1E+02 0.0017 27.3 6.5 114 5-138 11-146 (159)
17 PF09870.9 ; DUF2097 ; Uncharac 48.7 1.6E+02 0.0025 25.2 6.6 60 23-82 5-69 (92)
18 2PXG_A Outer membrane protein; 43.7 24 0.00037 30.5 1.2 20 239-258 26-45 (118)
19 3GMX_B BLP; 2-layer alpha/beta 43.0 29 0.00045 30.9 1.6 20 239-258 12-31 (154)
20 5D0O_E Outer membrane protein 41.4 33 0.00051 29.0 1.6 20 239-258 46-65 (123)
21 3D4E_A putative beta-lactamase 39.1 83 0.0013 29.2 4.0 58 239-310 31-97 (179)
22 3D4E_A putative beta-lactamase 36.9 3E+02 0.0046 25.5 7.4 105 19-139 31-166 (179)
23 PF14454.6 ; Prok_Ub ; Prokaryo 36.6 88 0.0014 24.4 3.1 30 88-117 5-34 (62)
24 3N4I_B Crystal structure of th 36.4 43 0.00067 30.7 1.7 20 239-258 12-31 (165)
25 3GMX_B BLP; 2-layer alpha/beta 34.7 44 0.00068 29.8 1.4 20 239-258 85-104 (154)
26 PF14172.6 ; DUF4309 ; Domain o 34.6 71 0.0011 28.2 2.7 51 239-307 18-69 (135)
27 PF12978.7 ; DUF3862 ; Domain o 34.2 54 0.00083 29.3 1.9 20 239-258 95-114 (159)
28 4H0A_A Uncharacterized protein 30.9 61 0.00094 33.0 1.8 21 239-259 43-63 (323)
29 PF06185.12 ; YecM ; YecM prote 30.1 3.4E+02 0.0053 25.8 6.5 60 13-73 102-167 (175)
30 4IL7_A Putative uncharacterize 29.8 6.8E+02 0.011 22.7 8.4 133 7-175 9-157 (166)
31 3D4E_A putative beta-lactamase 26.3 89 0.0014 29.0 1.9 20 239-258 114-133 (179)
32 3N4I_B Crystal structure of th 24.4 1.1E+02 0.0016 28.1 2.0 20 239-258 91-110 (165)
33 PF07467.11 ; BLIP ; Beta-lacta 23.8 89 0.0014 26.8 1.3 21 239-259 81-101 (121)
34 PF07467.11 ; BLIP ; Beta-lacta 21.6 3.9E+02 0.006 22.8 4.9 88 19-114 8-96 (121)
No 1
>PF03676.14 ; UPF0183 ; Uncharacterised protein family (UPF0183)
Probab=100.00 E-value=9.9e-102 Score=792.76 Aligned_cols=376 Identities=53% Similarity=0.957 Sum_probs=0.0 Template_Neff=7.100
Q ss_pred CCcHHHHHHHHHHccCCcCcEEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEecCCCCEEEECCEEecCCCC
Q sp|Q9BSU1|CP07 22 GMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKVKLKYCGVHFNSQAI 101 (422)
Q Consensus 22 G~sL~~vi~~Lr~~~~~~~~vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~d~~~~~L~Y~~~~~~~~~~ 101 (422)
|||||+||++||++.+.+++|+|+|++++|++.||+|.|+++||||+||+.+|||++|||+|+++++|+|+++.|++++.
T Consensus 1 G~~L~~vi~~L~~~~~~~~~Vel~Ys~~~p~~~~Ivl~L~~~glrL~Fd~~~QrL~lIEv~d~~~~~L~Y~~~~~~~~~~ 80 (394)
T H9J4A9_BOMMO/5 1 GMHFSQSVAIIQSQVGTIRGVQVLYSDQNPLSVDLVINMPQDGMRLIFDPVAQRLKIIEIYNMKLVKLRYSGMCFNSPEI 80 (394)
T ss_pred CCcHHHHHHHHHhcCCccceEEEEECCCCCCCCcEEEEcCCCceEEEEcCccCeEEEEEEEcCCCcEEEEcCeeecCCCC
Q ss_pred CCcHHHHHHhhcCCCCCCccCcccEEEEEeCcEEEEeeCcccCCCCccCCCcccccccCCCCCCC--eEEEEEEEeCCCh
Q sp|Q9BSU1|CP07 102 APTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGA--TVKRMYIYSGNSL 179 (422)
Q Consensus 102 ~ptf~~I~~~FGPTyPG~yd~~~~~Y~LsYpGisF~Fpi~~~~~~~~~~~~~~~~l~~l~~~~~~--~~s~i~If~G~s~ 179 (422)
.|||++||++|||||||+|+++++.|+||||||+|.||+++ ++.+.+..++.+++++++. .|++|+||+|++|
T Consensus 81 ~~t~~~Iy~~FGPTyPG~~d~~~~~y~LsYpGisF~F~~~~-----~~~~~~~~~~~~l~~~~~~~~~~~~m~If~G~~~ 155 (394)
T H9J4A9_BOMMO/5 81 TPSIEQVEHCFGATHPGLYDSQRHLFALNFRGLSFYFPVDS-----KFEPGYAHGLGSLQFPNGGSPVVSRTTIYYGSQH 155 (394)
T ss_pred CCcHHHHHHHhcCCCCCcccCCCCeEEEEeCcEEEEeeCCc-----ccCCCCccccccccCCCCCCCceEEEEEEeCCcc
Q ss_pred H---------hcCC-CCCCcccccCcceeeEEEEeeCCCCCceEEEEEEecCCCCccccccceeEEEEEEEecCCHHHHH
Q sp|Q9BSU1|CP07 180 Q---------DTKA-PMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVL 249 (422)
Q Consensus 180 ~---------~~~~-~~~p~~~~~~~~~~~~v~v~~~~~~~~gl~~~~~~~~~~~~~~~~~~~~~~~~~I~~G~T~QDVl 249 (422)
. ++.. |.+|.+|+.++.+.++|++.+......|+++.|...+. ....+..+....++|.||+|+|||+
T Consensus 156 ~~~~~~~~~~~~~~~p~~p~~~~~~~~~~~~v~v~~~~~~~~gl~l~f~~~~~--~~~~~~~~~~~~~~I~~G~t~QDVl 233 (394)
T H9J4A9_BOMMO/5 156 QLSSNTSSRVSGVPLPDLPLSCYRQQLHLRRCDVLRNTTSTMGLRLHMFTEGT--SRALEPSQVALVRVVRFGDSCQGVA 233 (394)
T ss_pred ccccccccccCCCCCCCCCchhcCCCCceEEEEEEEcCCCCceEEEEEEcCCC--CCcCCccceeceEEEEecCCHHHHH
Q ss_pred HHhcCCcEEEEeccccccccCCCCCcCCCCcCCccchhhHhhccceeecCCCCEEEEEEecCCCCCCccccccccCcEEe
Q sp|Q9BSU1|CP07 250 SMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKI 329 (422)
Q Consensus 250 ~~LG~P~~~f~K~ddrm~IH~~~~~~~~~~~~~dyF~NYF~lG~DiLfd~~t~~v~KiILHtN~PG~~~F~~Y~RC~w~i 329 (422)
++||+|+++|||+||||+||+...++. .....+||||||+||||||||+.||+|+|||||||+|||++|++|+||+|+|
T Consensus 234 ~~LG~P~~~f~K~ddrm~Ih~~~~~~~-~~~~~~yF~NYF~lG~DiLfd~~th~v~KiILHtN~Pg~~~F~~Y~RC~~~l 312 (394)
T H9J4A9_BOMMO/5 234 RALGAPARLYYKADDKMRIHRPTARRR-PPPASDYLFNYFTLGLDVLFDARTNQVKKFVLHTNYPGHYNFNMYHRCEFEL 312 (394)
T ss_pred HHhCCCceEEEcCcccccccCCCCCCC-CCCcchhchhHHHhCcceeecCCCcEEEEEEeeCCCCCCccccccccCeEEE
Q ss_pred eccccccCCCC------CcceeccCcCHHHHHHHhCCCCCCCeEeeCCCCCCCCCCCCceEEeccCCEEEEEecCCCEEE
Q sp|Q9BSU1|CP07 330 PLAIKKENADG------QTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIAS 403 (422)
Q Consensus 330 ~~~~~~~~~~~------~~~~it~~~~~~~i~~~l~~~~~~pvvlnR~~s~~~~~~fg~T~~yG~~g~IfEVm~ng~Ias 403 (422)
..... +.+.. +...++++++|++|++.| ....+||||||+++++..++||+|+||||+|||||||+||+|||
T Consensus 313 ~~~~~-~~~~~~~~~~~~~~~i~~~~~~~~i~~~l-~~~~~p~vlnR~~~~~~~~~~g~T~lyg~~g~ifEV~~ng~Ias 390 (394)
T H9J4A9_BOMMO/5 313 TVQPD-KSEAHSLVESGGGVAVTAYSKWEVVSRAL-RVCERPVVLNRASSTNTTNPFGSTFCYGYQDIIFEVMSNNYIAS 390 (394)
T ss_pred EeCCC-cchhcceecCCCCceecCcccHHHHHHHh-ccCCCCEEEecCCCCCCCCCCCcEEEEecCCEEEEEecCCcEEE
Q ss_pred EEEe
Q sp|Q9BSU1|CP07 404 VTLY 407 (422)
Q Consensus 404 vTl~ 407 (422)
||||
T Consensus 391 vtlf 394 (394)
T H9J4A9_BOMMO/5 391 ITLY 394 (394)
T ss_pred EEeC
No 2
>PF12978.7 ; DUF3862 ; Domain of Unknown Function with PDB structure (DUF3862)
Probab=71.77 E-value=67 Score=28.65 Aligned_cols=127 Identities=14% Similarity=0.172 Sum_probs=0.0 Template_Neff=9.600
Q ss_pred EEe---------cCCHHHHHHHhcCCcEEEEeccccccccCCCCCcCCCCcCCccchhhHhhccceeecCCCCEEEEEEe
Q sp|Q9BSU1|CP07 239 VYF---------GDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVL 309 (422)
Q Consensus 239 I~~---------G~T~QDVl~~LG~P~~~f~K~ddrm~IH~~~~~~~~~~~~~dyF~NYF~lG~DiLfd~~t~~v~KiIL 309 (422)
|.+ |.|.+||.+.||.|..+---..+ ......|-|+|...++.+.|+ ....+.|-+.
T Consensus 12 i~~~~~~~~~~~G~t~~eV~~~lG~p~~~~~~~~~-------------~~~~~~~~w~~~~~~~~v~~~-~~~~~~~~~~ 77 (159)
T Q8DTX1_STRMU/4 12 IKVTTDQNHFSGGTSIEQLKQWFGDPNKSEQRNAG-------------NITLDSYTWVKDGAVINAQLY-KNSTVARSIS 77 (159)
T ss_pred eeecCCcccCCCCCCHHHHHHHHCCCceEEeeeeC-------------CeEEEEEEEEeCCeEEEEEEE-CCEEEEEEEE
Q ss_pred -----cCCCCCCccccccccCcEEeeccccccCCCCCcceeccCcCHHHHHHHhCCCCCCCeEeeCCCCCCCCCCCCceE
Q sp|Q9BSU1|CP07 310 -----HTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTF 384 (422)
Q Consensus 310 -----HtN~PG~~~F~~Y~RC~w~i~~~~~~~~~~~~~~~it~~~~~~~i~~~l~~~~~~pvvlnR~~s~~~~~~fg~T~ 384 (422)
+++.+-...|. .+...+..++|.+.+ ++|........ ........
T Consensus 78 ~~~~~~~~~~t~~~~~-----------------------~i~~G~t~~eV~~~l----G~p~~~~~~~~---~~~~~~~~ 127 (159)
T Q8DTX1_STRMU/4 78 NFSFSREAKIGKEDYD-----------------------ELKIGESYKKVVEKL----GEPDVLSQSMS---SDKEEMQT 127 (159)
T ss_pred eceecCCCCCCHHHHH-----------------------hcCCCCCHHHHHHHH----CCCCeeEEEee---CCceEEEE
Q ss_pred EeccC------CEEEEEe-cCCCEEEEEEeCC
Q sp|Q9BSU1|CP07 385 CFGLQ------RMIFEVM-QNNHIASVTLYGP 409 (422)
Q Consensus 385 ~yG~~------g~IfEVm-~ng~IasvTl~~~ 409 (422)
.|.+. +..+-+. .||.|.++.-+..
T Consensus 128 ~~~~~~~~~~~~~~~~~~F~~g~l~~~~~~g~ 159 (159)
T Q8DTX1_STRMU/4 128 VWSSGIKTKSSSATIELYFENGLLKNKTQKDL 159 (159)
T ss_pred EEEecccCCCCCcEEEEEEECCeEEEeEecCC
No 3
>PF04355.13 ; SmpA_OmlA ; SmpA / OmlA family
Probab=70.25 E-value=4.9 Score=30.39 Aligned_cols=20 Identities=30% Similarity=0.363 Sum_probs=0.0 Template_Neff=10.200
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||++.||.|..+
T Consensus 12 i~~Gmt~~eV~~~lG~P~~~ 31 (73)
T A6W2D6_MARMS/3 12 LQIGMSESQVTYLLGNPMLR 31 (73)
T ss_pred CCCCCCHHHHHHHHCCCcee
No 4
>5EKQ_E Outer membrane protein assembly factor; membrane protein, insertase, beta-barrel, outer; 3.392A {Escherichia coli (strain K12)}; Related PDB entries: 2KM7_A 2KXX_A 5AYW_E 5LJO_E
Probab=68.06 E-value=5.9 Score=32.02 Aligned_cols=20 Identities=30% Similarity=0.380 Sum_probs=0.0 Template_Neff=9.600
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||++.||+|..+
T Consensus 27 l~~G~t~~eV~~~lG~P~~~ 46 (94)
T 5EKQ_E 27 IRVGMTQQQVAYALGTPLMS 46 (94)
T ss_dssp CCTTCCSTTTTTSSCCCSEE
T ss_pred CCCCCCHHHHHHHhCCCcee
No 5
>PF11399.8 ; DUF3192 ; Protein of unknown function (DUF3192)
Probab=58.72 E-value=13 Score=30.74 Aligned_cols=20 Identities=15% Similarity=0.388 Sum_probs=0.0 Template_Neff=9.500
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|-+||+..||.|..+
T Consensus 34 i~~Gmtk~eV~~~lG~P~~~ 53 (104)
T A3QGB8_SHELP/1 34 LSLGMTRDQVMTLMGTADFN 53 (104)
T ss_pred cCCCCCHHHHHHHhCCCcee
No 6
>5WAM_B Outer membrane protein assembly factor; beta-barrel assembly machinery, BAM complex; 2.45A {Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)}; Related PDB entries: 5WAM_A
Probab=58.46 E-value=11 Score=31.36 Aligned_cols=20 Identities=35% Similarity=0.376 Sum_probs=0.0 Template_Neff=9.400
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||+..||.|+.+
T Consensus 30 l~~G~t~~eV~~~lG~P~~~ 49 (108)
T 5WAM_B 30 LRPGMTKDQVLLLLGSPILR 49 (108)
T ss_dssp CCTTCBHHHHHHHHCCCSCC
T ss_pred CCCCCCHHHHHHHHCCCcee
No 7
>3GMX_B BLP; 2-layer alpha/beta sandwich, PROTEIN BINDING; HET: ACT; 1.05A {Streptomyces clavuligerus} SCOP: d.98.1.0; Related PDB entries: 3GMX_A 3GMY_A 3GMY_B
Probab=57.72 E-value=1.6e+02 Score=26.08 Aligned_cols=109 Identities=11% Similarity=0.028 Sum_probs=0.0 Template_Neff=9.400
Q ss_pred EEcCCcHHHHHHHHHHccCCcCc--EEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEecCC-CCEEEECCEE
Q sp|Q9BSU1|CP07 19 FTLGMPLAQAVAILQKHCRIIKN--VQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLT-KVKLKYCGVH 95 (422)
Q Consensus 19 f~LG~sL~~vi~~Lr~~~~~~~~--vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~d~~-~~~L~Y~~~~ 95 (422)
+++||+..+|.++|-.-...... -...|.........+.|.+..+| +|..+++..+. .-.-......
T Consensus 12 I~~G~s~~eV~~~lG~p~~~~~~~~~~~~W~~~~~~~~~~~v~f~~~~----------kv~~k~~~~~~~~~~~~~t~~~ 81 (154)
T 3GMX_B 12 IQFGMDRTLVWQLAGADQSCSDQVERIICYNNPDHYGPQGHFFFNAAD----------KLIHKRQMELFPAPKPTMRLAT 81 (154)
T ss_dssp CCTTCBHHHHHHHHTHHHHEEECSSCEEEESSSCTTSSEEEEEECTTS----------BEEEEEEESSSCCSSCCCCHHH
T ss_pred CCCCCCHHHHHHHhCCCceecCCceeEEEEcCCCCCcceEEEEEccCC----------EEEEEEecccCCCCCCCCCHHH
Q ss_pred ecCCCCCCcHHHHHHhhcCCCCCCccC----------cccEEEEEeC--------cEEEEee
Q sp|Q9BSU1|CP07 96 FNSQAIAPTIEQIDQSFGATHPGVYNS----------AEQLFHLNFR--------GLSFSFQ 139 (422)
Q Consensus 96 ~~~~~~~ptf~~I~~~FGPTyPG~yd~----------~~~~Y~LsYp--------GisF~Fp 139 (422)
+..=....|..+|.+++|+ |+.... ....|...|. .+.|.|.
T Consensus 82 ~~~i~~Gmt~~~V~~~lG~--p~~~~~~~~~~~~~~~~~~~~~y~~~~~~~~~~~~~~~~F~ 141 (154)
T 3GMX_B 82 YNKTQTGMTEAQFWAAVPS--DTCSALAEQYPNWPATNGNLREYVCPSKAERFAPSAYFTFT 141 (154)
T ss_dssp HTTCCTTCBHHHHHHHSCG--GGCEEEEEECTTTTSCTTCEEEEEEESSSSTTCCEEEEEEE
T ss_pred HhhcCCCCCHHHHHHHcCC--ccceeceeccCCCCCCCCeEEEEEeCCCCCCCCCeEEEEEE
No 8
>PF14504.6 ; CAP_assoc_N ; CAP-associated N-terminal
Probab=57.07 E-value=24 Score=30.56 Aligned_cols=70 Identities=7% Similarity=0.027 Sum_probs=0.0 Template_Neff=10.000
Q ss_pred EEecCCHHHHHHHhcCCcEEEEeccccccccCCCCCcCCCCcCCccchhhHhhccceeecCCCCEEEEEEecCC
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTN 312 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~f~K~ddrm~IH~~~~~~~~~~~~~dyF~NYF~lG~DiLfd~~t~~v~KiILHtN 312 (422)
|.+|+|.++|++.+|.|....++.++....-...... ......+.+-...+-+.||..+++|.-|-+...
T Consensus 62 i~vG~t~~~v~~~~G~p~~~~~~~~~~~~~~~~~~~~----~~~~~~~~~~~~~~~~~fd~~~~~v~~I~~~~~ 131 (140)
T U5LAW6_9BACI/1 62 FHIGQPVSEIYSSVFIDTNINFQYKGSSYRFELSEDD----LNTRPLIKAGNIYAQLYIDRFTGELSSIRYMDA 131 (140)
T ss_pred ccCCCcHHHHHHhhcCCceEEEEEcCcEEEEEeCcch----hccceeEEECCEEEEEEEECCCCEEEEEEEecH
No 9
>2YH9_C SMALL PROTEIN A; LIPOPROTEIN, 3D DOMAIN SWAP, MEMBRANE; HET: MSE; 1.8A {ESCHERICHIA COLI}; Related PDB entries: 2YH9_B 2YH9_A
Probab=56.37 E-value=14 Score=29.98 Aligned_cols=20 Identities=30% Similarity=0.380 Sum_probs=0.0 Template_Neff=8.700
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||++.||+|..+
T Consensus 13 l~~Gmtk~eV~~lLG~P~~~ 32 (88)
T 2YH9_C 13 IRVGMTQQQVAYALGTPLMS 32 (88)
T ss_dssp CCTTCBHHHHHHHHCSCSEE
T ss_pred CCCCCCHHHHHHHhCCCcee
No 10
>PF14504.6 ; CAP_assoc_N ; CAP-associated N-terminal
Probab=56.24 E-value=30 Score=29.96 Aligned_cols=54 Identities=11% Similarity=0.142 Sum_probs=0.0 Template_Neff=10.000
Q ss_pred ecCCHHHHHHHhcCCcEEEEeccccccccCCCCCcCCCCcCCccchhhHh-hccceeecCCCCEEEEEEecCC
Q sp|Q9BSU1|CP07 241 FGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFT-LGVDILFDANTHKVKKFVLHTN 312 (422)
Q Consensus 241 ~G~T~QDVl~~LG~P~~~f~K~ddrm~IH~~~~~~~~~~~~~dyF~NYF~-lG~DiLfd~~t~~v~KiILHtN 312 (422)
+|+|.++|.+.||.|++...-.++ ...|.|-. .|--+.+....++|..|.+-++
T Consensus 1 lG~~~~~v~~~lG~P~~~~~~~~g------------------~~~~~Y~~~~~~~~~v~~~~~~v~~i~~~~~ 55 (140)
T U5LAW6_9BACI/1 1 IGKNASDLQVLLGDPERKDPSEYG------------------YEWWIYKKGTSQYVQAGVLDGRIVTLFATGP 55 (140)
T ss_pred CCCCHHHHHHHHCCCcEEeccccC------------------CeEEEEecCCCcEEEEEEECCEEEEEEEcCC
No 11
>4DM5_A Osmotically inducible lipoprotein OsmE; lipoprotein, UNKNOWN FUNCTION; HET: MSE; 1.5A {Pseudomonas aeruginosa PAO1}; Related PDB entries: 4DM5_C 4DM5_D 4DM5_B
Probab=56.21 E-value=14 Score=31.47 Aligned_cols=20 Identities=40% Similarity=0.433 Sum_probs=0.0 Template_Neff=7.400
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||+..||+|..+
T Consensus 24 I~~GmTk~qV~~~lG~P~~~ 43 (103)
T 4DM5_A 24 VEKGMSQQEVLRIGGTPSGT 43 (103)
T ss_dssp CCTTCBHHHHHHHHCSCSEE
T ss_pred CCCCCCHHHHHHHhCCCCee
No 12
>PF14504.6 ; CAP_assoc_N ; CAP-associated N-terminal
Probab=56.09 E-value=77 Score=27.35 Aligned_cols=65 Identities=22% Similarity=0.238 Sum_probs=0.0 Template_Neff=10.000
Q ss_pred CCCCccEEcCCcHHHHHHHHHHccCC-----cCcEEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEec
Q sp|Q9BSU1|CP07 13 GNEQWEFTLGMPLAQAVAILQKHCRI-----IKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCD 83 (422)
Q Consensus 13 G~~~~~f~LG~sL~~vi~~Lr~~~~~-----~~~vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~d 83 (422)
| +++||+..++++.+-.-... -....+.+.....-..++.-. .+..+.+.||+..-+++.|.+.+
T Consensus 61 g-----i~vG~t~~~v~~~~G~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~fd~~~~~v~~I~~~~ 130 (140)
T U5LAW6_9BACI/1 61 P-----FHIGQPVSEIYSSVFIDTNINFQYKGSSYRFELSEDDLNTRPLIKA-GNIYAQLYIDRFTGELSSIRYMD 130 (140)
T ss_pred C-----ccCCCcHHHHHHhhcCCceEEEEEcCcEEEEEeCcchhccceeEEE-CCEEEEEEEECCCCEEEEEEEec
No 13
>PF14172.6 ; DUF4309 ; Domain of unknown function (DUF4309)
Probab=53.82 E-value=2.4e+02 Score=24.83 Aligned_cols=119 Identities=8% Similarity=0.090 Sum_probs=0.0 Template_Neff=8.400
Q ss_pred ccccCCCCccEEcCCc-HHHHHHHHHHccCCcCcEEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEecCCCC
Q sp|Q9BSU1|CP07 9 ERSLGNEQWEFTLGMP-LAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKV 87 (422)
Q Consensus 9 g~~LG~~~~~f~LG~s-L~~vi~~Lr~~~~~~~~vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~d~~~~ 87 (422)
|+-.|. +|.||++ +.+|.+.+-+ .-+..|.+.. ..........++.+-|+... ++..|+..+..--
T Consensus 11 Gk~~g~---~~~lG~s~~~~V~~~~G~------P~~~~~~~~~---~g~~~~Y~~~~~~f~~~~~~-~v~~i~~~~~~~~ 77 (135)
T R4K5N0_CLOPA/8 11 GKVFNS---DFPAKDTNIDSVESKWGK------ADNSEWVASA---KGLYSTYSKHNIVFGSNKGG-QIFEVRSLDKQLG 77 (135)
T ss_pred CCCCCC---CCCCCCCcHHHHHHHhCC------CCceehhhhc---CceeEEecCceEEEEECCCC-eEEEEEEechhhc
Q ss_pred EEEECCEEecCCCCCCcHHHHHHhhcCCCCCCccCcccEEEEEe-Cc----EEEEeeCcccCCCCccCCCcccccccCCC
Q sp|Q9BSU1|CP07 88 KLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNF-RG----LSFSFQLDSWTEAPKYEPNFAHGLASLQI 162 (422)
Q Consensus 88 ~L~Y~~~~~~~~~~~ptf~~I~~~FGPTyPG~yd~~~~~Y~LsY-pG----isF~Fpi~~~~~~~~~~~~~~~~l~~l~~ 162 (422)
. .|+.+|.+.+| -|..-....+.|.+.| .| +.|.|+.+...
T Consensus 78 ~--------------lt~~~v~~~LG--~P~~~~~~~~~~~~~Y~~g~~y~L~f~~~~~~~~------------------ 123 (135)
T R4K5N0_CLOPA/8 78 N--------------IYLSMVKDKLG--TPQHDVKVNGEEIIGYKMGNDFKILFVFPEPTNQ------------------ 123 (135)
T ss_pred C--------------CCHHHHHHHhC--CCcEEEEECCEEEEEEEeCCCEEEEEEeCCCCCC------------------
Q ss_pred CCCCeEEEEEEE
Q sp|Q9BSU1|CP07 163 PHGATVKRMYIY 174 (422)
Q Consensus 163 ~~~~~~s~i~If 174 (422)
..++.+.+|.||
T Consensus 124 ~~~~~v~~i~v~ 135 (135)
T R4K5N0_CLOPA/8 124 HANPIMSHYSVL 135 (135)
T ss_pred CCCCeeeEEEeC
No 14
>PF07467.11 ; BLIP ; Beta-lactamase inhibitor (BLIP)
Probab=52.88 E-value=16 Score=31.41 Aligned_cols=20 Identities=20% Similarity=0.320 Sum_probs=0.0 Template_Neff=8.800
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|.+|+|.+||++.||.|.++
T Consensus 8 I~~G~t~~~V~~~lG~P~~~ 27 (121)
T B5GLC0_STRC2/3 8 IQFGMDRTLVWQLAGADQSC 27 (121)
T ss_pred CCCCCCHHHHHHHHCCCcee
No 15
>PF11006.8 ; DUF2845 ; Protein of unknown function (DUF2845)
Probab=50.88 E-value=27 Score=28.63 Aligned_cols=27 Identities=19% Similarity=0.145 Sum_probs=0.0 Template_Neff=8.700
Q ss_pred EEecCCHHHHHHHhcCCcEEEEecccc
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKVFYKSEDK 265 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~f~K~ddr 265 (422)
|..|+|..+|+..+|.|.......+..
T Consensus 11 V~~Gds~~~Vl~~cG~P~~~~~~~~~~ 37 (94)
T B3PEX3_CELJU/2 11 TQTGDTKAEVIAKCGDPVFTDHYCAPM 37 (94)
T ss_pred cCCCCCHHHHHHHhCCCcEEEeEeeec
No 16
>PF12978.7 ; DUF3862 ; Domain of Unknown Function with PDB structure (DUF3862)
Probab=49.44 E-value=1.1e+02 Score=27.28 Aligned_cols=114 Identities=9% Similarity=0.155 Sum_probs=0.0 Template_Neff=9.600
Q ss_pred EeccccccCCCCccEEcCCcHHHHHHHHHHccCCcCcE-------EEEECCCCCcCCCEEEEeCCCCeEEEecCccceee
Q sp|Q9BSU1|CP07 5 EVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNV-------QVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLK 77 (422)
Q Consensus 5 ~i~Pg~~LG~~~~~f~LG~sL~~vi~~Lr~~~~~~~~v-------el~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~ 77 (422)
+|.++.+++. ++-||+..+|++.|-+-......- ...|.. +..++.+.|+ ..++.
T Consensus 11 ~i~~~~~~~~----~~~G~t~~eV~~~lG~p~~~~~~~~~~~~~~~~~w~~------------~~~~~~v~~~--~~~~~ 72 (159)
T Q8DTX1_STRMU/4 11 KIKVTTDQNH----FSGGTSIEQLKQWFGDPNKSEQRNAGNITLDSYTWVK------------DGAVINAQLY--KNSTV 72 (159)
T ss_pred ceeecCCccc----CCCCCCHHHHHHHHCCCceEEeeeeCCeEEEEEEEEe------------CCeEEEEEEE--CCEEE
Q ss_pred EEEEecCCCC-EEEECCEEecCCCCCCcHHHHHHhhcCCCCCCccCcc----cEEEEEeC----------cEEEEe
Q sp|Q9BSU1|CP07 78 VIEVCDLTKV-KLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAE----QLFHLNFR----------GLSFSF 138 (422)
Q Consensus 78 lIEv~d~~~~-~L~Y~~~~~~~~~~~ptf~~I~~~FGPTyPG~yd~~~----~~Y~LsYp----------GisF~F 138 (422)
-+.+..+.-. .=......+..-...-|..+|.+.+| .|+...... ....+.|. .+.|.|
T Consensus 73 ~~~~~~~~~~~~~~~t~~~~~~i~~G~t~~eV~~~lG--~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~F 146 (159)
T Q8DTX1_STRMU/4 73 ARSISNFSFSREAKIGKEDYDELKIGESYKKVVEKLG--EPDVLSQSMSSDKEEMQTVWSSGIKTKSSSATIELYF 146 (159)
T ss_pred EEEEEeceecCCCCCCHHHHHhcCCCCCHHHHHHHHC--CCCeeEEEeeCCceEEEEEEEecccCCCCCcEEEEEE
No 17
>PF09870.9 ; DUF2097 ; Uncharacterized protein conserved in archaea (DUF2097)
Probab=48.69 E-value=1.6e+02 Score=25.16 Aligned_cols=60 Identities=18% Similarity=0.331 Sum_probs=0.0 Template_Neff=4.200
Q ss_pred CcHHHHHHHHHHccCCcCcEEEEECCCCCcCCCEEEEe----CCCCeEEEecCccceee-EEEEe
Q sp|Q9BSU1|CP07 23 MPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNL----TQDGIKLMFDAFNQRLK-VIEVC 82 (422)
Q Consensus 23 ~sL~~vi~~Lr~~~~~~~~vel~Ys~~~pl~~~Ivi~L----~~~GirL~Fd~~~QrL~-lIEv~ 82 (422)
|+--+++++++.+-.....++|.|+.--.-..=+.+.- ...|++++-+-..+.|. +|||.
T Consensus 5 m~~dE~ieYik~nVk~~D~lEisynRvf~pGeVl~i~~~~~~~~~~~~v~l~l~ge~~~~~veiD 69 (92)
T A5UN43_METS3/2 5 LTPDKAVEYLKDNVKIHDNLEISYNRIFGSGEVLNMDFSEYFGKPGFKMLLSLDGDSINPTIEID 69 (92)
T ss_pred cCHHHHHHHHHHhCCccCeEEEEeceeecceeEEEEeeceecCCCeEEEEEEeCCCeecceEEEe
No 18
>2PXG_A Outer membrane protein; two layer alpha/beta plait, two; NMR {Xanthomonas axonopodis pv. citri}
Probab=43.68 E-value=24 Score=30.46 Aligned_cols=20 Identities=35% Similarity=0.526 Sum_probs=0.0 Template_Neff=8.300
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||+..||+|..+
T Consensus 26 I~~G~Tk~eV~~~LG~P~~~ 45 (118)
T 2PXG_A 26 LQVGQSKQQVSALLGTPSIP 45 (118)
T ss_dssp TCCCSCHHHHHHHHTSCCCC
T ss_pred CCCCCCHHHHHHHhCCCccC
No 19
>3GMX_B BLP; 2-layer alpha/beta sandwich, PROTEIN BINDING; HET: ACT; 1.05A {Streptomyces clavuligerus} SCOP: d.98.1.0; Related PDB entries: 3GMX_A 3GMY_A 3GMY_B
Probab=42.97 E-value=29 Score=30.94 Aligned_cols=20 Identities=20% Similarity=0.320 Sum_probs=0.0 Template_Neff=9.400
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|.+|.|.+||.+.||.|..+
T Consensus 12 I~~G~s~~eV~~~lG~p~~~ 31 (154)
T 3GMX_B 12 IQFGMDRTLVWQLAGADQSC 31 (154)
T ss_dssp CCTTCBHHHHHHHHTHHHHE
T ss_pred CCCCCCHHHHHHHhCCCcee
No 20
>5D0O_E Outer membrane protein assembly factor; E.coli, Bacterial outer membrane beta; 2.9A {Escherichia coli}; Related PDB entries: 5D0Q_E 5D0Q_I
Probab=41.38 E-value=33 Score=29.00 Aligned_cols=20 Identities=30% Similarity=0.380 Sum_probs=0.0 Template_Neff=9.900
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||+..||.|+..
T Consensus 46 l~~G~t~~eV~~~lG~P~~~ 65 (123)
T 5D0O_E 46 IRVGMTQQQVAYALGTPLMS 65 (123)
T ss_dssp CCSSCBHHHHHHHHCCCSBC
T ss_pred CCCCCCHHHHHHHhCCCcee
No 21
>3D4E_A putative beta-lactamase inhibitor protein; NP_721579.1, putative beta-lactamase inhibitor protein; HET: EDO, MSE; 1.4A {Streptococcus mutans}
Probab=39.07 E-value=83 Score=29.23 Aligned_cols=58 Identities=12% Similarity=0.176 Sum_probs=0.0 Template_Neff=8.500
Q ss_pred EEe---------cCCHHHHHHHhcCCcEEEEeccccccccCCCCCcCCCCcCCccchhhHhhccceeecCCCCEEEEEEe
Q sp|Q9BSU1|CP07 239 VYF---------GDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVL 309 (422)
Q Consensus 239 I~~---------G~T~QDVl~~LG~P~~~f~K~ddrm~IH~~~~~~~~~~~~~dyF~NYF~lG~DiLfd~~t~~v~KiIL 309 (422)
|.+ |.|.+||...||.|..+-....+ ......|-|+|-..++.|.|+ ...++.|-+.
T Consensus 31 I~~g~~~~~~~~Gmt~~eV~~ilG~P~~~~~~~~~-------------~~~~~~~~W~~~~~~i~v~F~-~~kv~~k~~~ 96 (179)
T 3D4E_A 31 IKVTTDQNHFSGGTSIEQLKQWFGDPNKSEQRNAG-------------NITLDSYTWVKDGAVINAQLY-KNSTVARSIS 96 (179)
T ss_dssp CCCCCCTTTCCSSCCHHHHHHHHCSCSEEEEEEET-------------TEEEEEEEEEETTEEEEEEEE-TTEEEEEEEE
T ss_pred eeecCCccCCCCCCCHHHHHHHHCCCceeEEEeeC-------------CEEEEEEEEEeCCeEEEEEEE-CCeEEEeeee
Q ss_pred c
Q sp|Q9BSU1|CP07 310 H 310 (422)
Q Consensus 310 H 310 (422)
+
T Consensus 97 ~ 97 (179)
T 3D4E_A 97 N 97 (179)
T ss_dssp S
T ss_pred c
No 22
>3D4E_A putative beta-lactamase inhibitor protein; NP_721579.1, putative beta-lactamase inhibitor protein; HET: EDO, MSE; 1.4A {Streptococcus mutans}
Probab=36.91 E-value=3e+02 Score=25.55 Aligned_cols=105 Identities=10% Similarity=0.142 Sum_probs=0.0 Template_Neff=8.500
Q ss_pred EEc---------CCcHHHHHHHHHHccCCc-------CcEEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEe
Q sp|Q9BSU1|CP07 19 FTL---------GMPLAQAVAILQKHCRII-------KNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVC 82 (422)
Q Consensus 19 f~L---------G~sL~~vi~~Lr~~~~~~-------~~vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~ 82 (422)
+++ ||+..+|.++|=.-.... ......|.. ....|.+.|+ ..+|..+.+.
T Consensus 31 I~~g~~~~~~~~Gmt~~eV~~ilG~P~~~~~~~~~~~~~~~~~W~~------------~~~~i~v~F~--~~kv~~k~~~ 96 (179)
T 3D4E_A 31 IKVTTDQNHFSGGTSIEQLKQWFGDPNKSEQRNAGNITLDSYTWVK------------DGAVINAQLY--KNSTVARSIS 96 (179)
T ss_dssp CCCCCCTTTCCSSCCHHHHHHHHCSCSEEEEEEETTEEEEEEEEEE------------TTEEEEEEEE--TTEEEEEEEE
T ss_pred eeecCCccCCCCCCCHHHHHHHHCCCceeEEEeeCCEEEEEEEEEe------------CCeEEEEEEE--CCeEEEeeee
Q ss_pred cCCC-CEEEECCEEecCCCCCCcHHHHHHhhcCCCCCCccCccc----EEEEEe----------CcEEEEee
Q sp|Q9BSU1|CP07 83 DLTK-VKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQ----LFHLNF----------RGLSFSFQ 139 (422)
Q Consensus 83 d~~~-~~L~Y~~~~~~~~~~~ptf~~I~~~FGPTyPG~yd~~~~----~Y~LsY----------pGisF~Fp 139 (422)
.+.. -.-...-..+..-....|..+|.+++|. |........ ...+.| ..+.|.|.
T Consensus 97 ~~~~~~~~~it~~~~~~I~~Gmt~~eV~~~lG~--p~~~~~~~~~~~~~~~~~w~~~~~~~~~~~~i~~~F~ 166 (179)
T 3D4E_A 97 NFSFSREAKIGKEDYDELKIGESYKKIVEKLGE--PDVLSQSMSSDKEEMQTVWSSGIKTKSSSATIELYFE 166 (179)
T ss_dssp SCCCCCCCCBCHHHHHHCCTTCBHHHHHHHHCC--CSEEEEEECSSCEEEEEEECSSBCSSCTTCEEEEEEE
T ss_pred cCccccCCCCCHHHHHHCCCCCCHHHHHHHHCC--CceeeeecCCCceEEEEEEEcCCcCCCCccEEEEEEE
No 23
>PF14454.6 ; Prok_Ub ; Prokaryotic Ubiquitin
Probab=36.62 E-value=88 Score=24.38 Aligned_cols=30 Identities=23% Similarity=0.342 Sum_probs=0.0 Template_Neff=5.900
Q ss_pred EEEECCEEecCCCCCCcHHHHHHhhcCCCC
Q sp|Q9BSU1|CP07 88 KLKYCGVHFNSQAIAPTIEQIDQSFGATHP 117 (422)
Q Consensus 88 ~L~Y~~~~~~~~~~~ptf~~I~~~FGPTyP 117 (422)
+++|.+..+..|+...+.+++.+++..+||
T Consensus 5 ~F~~~~~~l~DP~P~~s~e~v~~~~a~~yP 34 (62)
T H8H183_DEIGI/2 5 VFKFDGKVLDDPNPKSTPEQVKTFYAPTYP 34 (62)
T ss_pred EEEECCEEecCCCCCCCHHHHHHHHHHhCH
No 24
>3N4I_B Crystal structure of the SHV-1; beta-lactamase, protein-protein complex, BLIP, SHV-1; 1.56A {Klebsiella pneumoniae} SCOP: d.98.1.1; Related PDB entries: 3E2K_D 1XXM_C 2G2W_B 3E2L_C 3GMU_B 1XXM_D 3C4P_B 1S0W_C 3C7U_D 3C4O_B 1JTG_B 3C7V_B 3C7V_D 3E2L_D 3E2K_C 2G2U_B 3C7U_B 2B5R_C 1JTG_D 2B5R_D 1S0W_D
Probab=36.36 E-value=43 Score=30.67 Aligned_cols=20 Identities=30% Similarity=0.464 Sum_probs=0.0 Template_Neff=8.500
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|.+|.|.+||.+.||.|...
T Consensus 12 I~~Gmt~~eV~~~lG~p~~~ 31 (165)
T 3N4I_B 12 IQFGMTRQQVLDIAGAENCE 31 (165)
T ss_dssp SCTTCCHHHHHHHHCGGGEE
T ss_pred CCCCCCHHHHHHHHCCCCee
No 25
>3GMX_B BLP; 2-layer alpha/beta sandwich, PROTEIN BINDING; HET: ACT; 1.05A {Streptomyces clavuligerus} SCOP: d.98.1.0; Related PDB entries: 3GMX_A 3GMY_A 3GMY_B
Probab=34.69 E-value=44 Score=29.77 Aligned_cols=20 Identities=10% Similarity=-0.059 Sum_probs=0.0 Template_Neff=9.400
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.+||+..||.|..+
T Consensus 85 i~~Gmt~~~V~~~lG~p~~~ 104 (154)
T 3GMX_B 85 TQTGMTEAQFWAAVPSDTCS 104 (154)
T ss_dssp CCTTCBHHHHHHHSCGGGCE
T ss_pred cCCCCCHHHHHHHcCCccce
No 26
>PF14172.6 ; DUF4309 ; Domain of unknown function (DUF4309)
Probab=34.59 E-value=71 Score=28.22 Aligned_cols=51 Identities=12% Similarity=0.088 Sum_probs=0.0 Template_Neff=8.400
Q ss_pred EEecCC-HHHHHHHhcCCcEEEEeccccccccCCCCCcCCCCcCCccchhhHhhccceeecCCCCEEEEE
Q sp|Q9BSU1|CP07 239 VYFGDS-CQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKF 307 (422)
Q Consensus 239 I~~G~T-~QDVl~~LG~P~~~f~K~ddrm~IH~~~~~~~~~~~~~dyF~NYF~lG~DiLfd~~t~~v~Ki 307 (422)
+.+|+| .+||...+|.|++..+-.++. ..++.|-..++-+-+|. ..+|.-|
T Consensus 18 ~~lG~s~~~~V~~~~G~P~~~~~~~~~~-----------------g~~~~Y~~~~~~f~~~~-~~~v~~i 69 (135)
T R4K5N0_CLOPA/8 18 FPAKDTNIDSVESKWGKADNSEWVASAK-----------------GLYSTYSKHNIVFGSNK-GGQIFEV 69 (135)
T ss_pred CCCCCCcHHHHHHHhCCCCceehhhhcC-----------------ceeEEecCceEEEEECC-CCeEEEE
No 27
>PF12978.7 ; DUF3862 ; Domain of Unknown Function with PDB structure (DUF3862)
Probab=34.21 E-value=54 Score=29.27 Aligned_cols=20 Identities=30% Similarity=0.610 Sum_probs=0.0 Template_Neff=9.600
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|.+|+|.++|++.||.|...
T Consensus 95 i~~G~t~~eV~~~lG~p~~~ 114 (159)
T Q8DTX1_STRMU/4 95 LKIGESYKKVVEKLGEPDVL 114 (159)
T ss_pred cCCCCCHHHHHHHHCCCCee
No 28
>4H0A_A Uncharacterized protein; CAP protein family, cysteine-rich secretory; HET: EDO, MSE; 1.9A {Staphylococcus aureus subsp. aureus}; Related PDB entries: 4H0A_B
Probab=30.93 E-value=61 Score=33.05 Aligned_cols=21 Identities=19% Similarity=0.498 Sum_probs=0.0 Template_Neff=9.000
Q ss_pred EEecCCHHHHHHHhcCCcEEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKVF 259 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~f 259 (422)
|.+|+|.+||.+.||.|.++.
T Consensus 43 i~iG~s~~~v~~~~G~P~r~~ 63 (323)
T 4H0A_A 43 TWVGKDIKVLTSKFGQADRVY 63 (323)
T ss_dssp GGTTSBTHHHHHHHCSCSEEE
T ss_pred HhcCCcHHHHHHHhCCCcEEE
No 29
>PF06185.12 ; YecM ; YecM protein
Probab=30.07 E-value=3.4e+02 Score=25.76 Aligned_cols=60 Identities=20% Similarity=0.191 Sum_probs=0.0 Template_Neff=6.200
Q ss_pred CCCCccEEcCCcHHHHHHHHHHccCCc--CcEEEEECCC----CCcCCCEEEEeCCCCeEEEecCcc
Q sp|Q9BSU1|CP07 13 GNEQWEFTLGMPLAQAVAILQKHCRII--KNVQVLYSEQ----SPLSHDLILNLTQDGIKLMFDAFN 73 (422)
Q Consensus 13 G~~~~~f~LG~sL~~vi~~Lr~~~~~~--~~vel~Ys~~----~pl~~~Ivi~L~~~GirL~Fd~~~ 73 (422)
|.+++||+++.++.+..+..++.-..+ +.++++.+.. +-+.+|- +.+..+|+...|.+.+
T Consensus 102 G~EHiEfVi~~~~~~~~~~~~~~~~~~~~~~i~~k~s~~~~~~~r~~NP~-~~~~~~~~~VKfH~~s 167 (175)
T Q7N560_PHOLL/9 102 GWEHVELVLPVAPEILSTAAKALLPQPLPAGFSVKESQPKGEQERLPNPT-LAITDGEITVKFHPFT 167 (175)
T ss_pred ceeEEEEEcCCCHHHHHHHHHHhCcCcCCCCCeeEecCCCCccccCCCce-EEeecCCEEEEEccCC
No 30
>4IL7_A Putative uncharacterized protein; partial jelly roll fold, hypothetical; 1.4A {Sulfolobus turreted icosahedral virus}
Probab=29.78 E-value=6.8e+02 Score=22.72 Aligned_cols=133 Identities=21% Similarity=0.270 Sum_probs=0.0 Template_Neff=1.300
Q ss_pred ccccccCCCCccEEcCCcHHHHHHHHHHccCCcCcEEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEecCCC
Q sp|Q9BSU1|CP07 7 VPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTK 86 (422)
Q Consensus 7 ~Pg~~LG~~~~~f~LG~sL~~vi~~Lr~~~~~~~~vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~d~~~ 86 (422)
+||++-| ++|... .+||-..-....+...|+..+|....-+|.|+ .-|+=.|+-..| ..||=...+.
T Consensus 9 ipgegtg-----I~Ls~G-----QiLkf~N~PlaEI~~~Ydpsn~S~vSS~VklK-GtIHPLFEvPsq--isien~Q~nE 75 (166)
T 4IL7_A 9 IPGEGTG-----IQLSAG-----QILKFYNVPIAEIIVEYDPSNVSGVSSNVKLK-GTIHPLFEVPSQ--ISIENFQPTE 75 (166)
T ss_dssp -------------------------------------------------------------------------------C
T ss_pred CCCCCcc-----eEeccc-----cEEEEecccHheEEEEeCCCCcCCccceeEee-eeeeeceeccee--eeeeccCCCC
Q ss_pred CEEEECCEEecCCCCCCcHHHHHHhhcCCCCCCccCcc----------------cEEEEEeCcEEEEeeCcccCCCCccC
Q sp|Q9BSU1|CP07 87 VKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAE----------------QLFHLNFRGLSFSFQLDSWTEAPKYE 150 (422)
Q Consensus 87 ~~L~Y~~~~~~~~~~~ptf~~I~~~FGPTyPG~yd~~~----------------~~Y~LsYpGisF~Fpi~~~~~~~~~~ 150 (422)
--|.|.+ ||...|-.|.-.. +...|++--+...|.....+.+-...
T Consensus 76 N~LI~sg------------------fgtslpq~y~~pangyl~~~itnt~tgnigqitl~~g~~tmtfnlqtgenkipvi 137 (166)
T 4IL7_A 76 NYLIYSG------------------FGTSLPQTYTIPANGYLIISITNTSTGNIGQITLTIGSTTMTFNLQTGENKIPVI 137 (166)
T ss_dssp EEEEEEE------------------EEEECSSCEECCSSEEEEEEEECSSCSEEEEEEEEETTEEEEEEEESEEEEEEEC
T ss_pred cEEEEec------------------CCCCCCceEEEcCCcEEEEEEEeCCCCceeEEEEEEeeEEEEEEeccCCccccEE
Q ss_pred CCcccccccCCCCCCCeEEEEEEEe
Q sp|Q9BSU1|CP07 151 PNFAHGLASLQIPHGATVKRMYIYS 175 (422)
Q Consensus 151 ~~~~~~l~~l~~~~~~~~s~i~If~ 175 (422)
......-.++ +..+.|-||.
T Consensus 138 agtqit~~~l-----ts~sailiye 157 (166)
T 4IL7_A 138 AGTQITNMTL-----TSSSAILIYE 157 (166)
T ss_dssp TTCEEEEEEE-----EEEEEEEEEE
T ss_pred eeceeEeeee-----cCcceEeeee
No 31
>3D4E_A putative beta-lactamase inhibitor protein; NP_721579.1, putative beta-lactamase inhibitor protein; HET: EDO, MSE; 1.4A {Streptococcus mutans}
Probab=26.30 E-value=89 Score=29.01 Aligned_cols=20 Identities=25% Similarity=0.605 Sum_probs=0.0 Template_Neff=8.500
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.++|+..||.|...
T Consensus 114 I~~Gmt~~eV~~~lG~p~~~ 133 (179)
T 3D4E_A 114 LKIGESYKKIVEKLGEPDVL 133 (179)
T ss_dssp CCTTCBHHHHHHHHCCCSEE
T ss_pred CCCCCCHHHHHHHHCCCcee
No 32
>3N4I_B Crystal structure of the SHV-1; beta-lactamase, protein-protein complex, BLIP, SHV-1; 1.56A {Klebsiella pneumoniae} SCOP: d.98.1.1; Related PDB entries: 3E2K_D 1XXM_C 2G2W_B 3E2L_C 3GMU_B 1XXM_D 3C4P_B 1S0W_C 3C7U_D 3C4O_B 1JTG_B 3C7V_B 3C7V_D 3E2L_D 3E2K_C 2G2U_B 3C7U_B 2B5R_C 1JTG_D 2B5R_D 1S0W_D
Probab=24.37 E-value=1.1e+02 Score=28.12 Aligned_cols=20 Identities=25% Similarity=0.287 Sum_probs=0.0 Template_Neff=8.500
Q ss_pred EEecCCHHHHHHHhcCCcEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKV 258 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~ 258 (422)
|..|.|.++|+..||.|..+
T Consensus 91 i~~Gmt~~eV~~~lG~p~~~ 110 (165)
T 3N4I_B 91 VTVGMTRAQVLATVGQGSCT 110 (165)
T ss_dssp CCTTCBHHHHHHHHCTBSEE
T ss_pred ccCCCCHHHHHHHHCCCcee
No 33
>PF07467.11 ; BLIP ; Beta-lactamase inhibitor (BLIP)
Probab=23.84 E-value=89 Score=26.82 Aligned_cols=21 Identities=10% Similarity=-0.092 Sum_probs=0.0 Template_Neff=8.800
Q ss_pred EEecCCHHHHHHHhcCCcEEE
Q sp|Q9BSU1|CP07 239 VYFGDSCQDVLSMLGSPHKVF 259 (422)
Q Consensus 239 I~~G~T~QDVl~~LG~P~~~f 259 (422)
|..|.|.++|...||.|..+.
T Consensus 81 i~~G~t~~~V~~~lG~p~~~~ 101 (121)
T B5GLC0_STRC2/3 81 TQTGMTEAQFWAAVPSDTCSA 101 (121)
T ss_pred cCCCCCHHHHHHhcCCccccc
No 34
>PF07467.11 ; BLIP ; Beta-lactamase inhibitor (BLIP)
Probab=21.56 E-value=3.9e+02 Score=22.84 Aligned_cols=88 Identities=13% Similarity=0.078 Sum_probs=0.0 Template_Neff=8.800
Q ss_pred EEcCCcHHHHHHHHHHccCCcCcEEEEECCCCCcCCCEEEEeCCCCeEEEecCccceeeEEEEecCCCCEEEECCEE-ec
Q sp|Q9BSU1|CP07 19 FTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKVKLKYCGVH-FN 97 (422)
Q Consensus 19 f~LG~sL~~vi~~Lr~~~~~~~~vel~Ys~~~pl~~~Ivi~L~~~GirL~Fd~~~QrL~lIEv~d~~~~~L~Y~~~~-~~ 97 (422)
+++||+..+|+++|-.-....+...-.|.-..+-. ....+.+.|++ ..+|..+++.++....=...... ++
T Consensus 8 I~~G~t~~~V~~~lG~P~~~~~~~~~~~~y~~~~~-------~~~~~~v~F~~-~gkv~~k~~~~~~~~~~~~~t~~~~~ 79 (121)
T B5GLC0_STRC2/3 8 IQFGMDRTLVWQLAGADQSCSDQVERIICYNNPDH-------YGPQGHFFFNA-ADKLIHKRQMELFPAPKPTMRLATYN 79 (121)
T ss_pred CCCCCCHHHHHHHHCCCceecCCcceEEEEeCCCC-------CCCEEEEEEcC-CCEEEEEEECCCCCCCCCCCCHHHHH
Q ss_pred CCCCCCcHHHHHHhhcC
Q sp|Q9BSU1|CP07 98 SQAIAPTIEQIDQSFGA 114 (422)
Q Consensus 98 ~~~~~ptf~~I~~~FGP 114 (422)
.-...-|..+|.+.||.
T Consensus 80 ~i~~G~t~~~V~~~lG~ 96 (121)
T B5GLC0_STRC2/3 80 KTQTGMTEAQFWAAVPS 96 (121)
T ss_pred hcCCCCCHHHHHHhcCC
|
