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% Generated by roxygen2: do not edit by hand
% Please edit documentation in R/mut_context.R
\name{mut_context}
\alias{mut_context}
\title{Retrieve context of base substitutions}
\usage{
mut_context(vcf, ref_genome, extension = 1)
}
\arguments{
\item{vcf}{A Granges object}
\item{ref_genome}{Reference genome}
\item{extension}{The number of bases, that's extracted upstream and
downstream of the base substitutions. (Default: 1).}
}
\value{
Character vector with the context of the base substitutions
}
\description{
A function to extract the bases 3' upstream and 5' downstream of the base
substitutions from the reference genome. The user an choose how many bases
are extracted.
}
\examples{
## See the 'read_vcfs_as_granges()' example for how we obtained the
## following data:
vcfs <- readRDS(system.file("states/read_vcfs_as_granges_output.rds",
package = "MutationalPatterns"
))
## Load the corresponding reference genome.
ref_genome <- "BSgenome.Hsapiens.UCSC.hg19"
library(ref_genome, character.only = TRUE)
## Get the standard context
mut_context <- mut_context(vcfs[[1]], ref_genome)
## Get larger context
mut_context_larger <- mut_context(vcfs[[1]], ref_genome, extension = 2)
}
\seealso{
\code{\link{read_vcfs_as_granges}},
}
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