1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220
|
// ==========================================================================
// SeqAn - The Library for Sequence Analysis
// ==========================================================================
// Copyright (c) 2006-2026, Knut Reinert, FU Berlin
// All rights reserved.
//
// Redistribution and use in source and binary forms, with or without
// modification, are permitted provided that the following conditions are met:
//
// * Redistributions of source code must retain the above copyright
// notice, this list of conditions and the following disclaimer.
// * Redistributions in binary form must reproduce the above copyright
// notice, this list of conditions and the following disclaimer in the
// documentation and/or other materials provided with the distribution.
// * Neither the name of Knut Reinert or the FU Berlin nor the names of
// its contributors may be used to endorse or promote products derived
// from this software without specific prior written permission.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
// AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
// IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
// ARE DISCLAIMED. IN NO EVENT SHALL KNUT REINERT OR THE FU BERLIN BE LIABLE
// FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
// DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
// SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
// CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
// LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
// OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH
// DAMAGE.
//
// ==========================================================================
// Author: Manuel Holtgrewe <manuel.holtgrewe@fu-berlin.de>
// ==========================================================================
#ifndef SEQAN_INCLUDE_SEQAN_ALIGN_LOCAL_ALIGNMENT_ENUMERATION_H_
#define SEQAN_INCLUDE_SEQAN_ALIGN_LOCAL_ALIGNMENT_ENUMERATION_H_
namespace seqan2 {
// ============================================================================
// Forwards
// ============================================================================
// ============================================================================
// Tags, Classes, Enums
// ============================================================================
// ----------------------------------------------------------------------------
// Class LocalAlignmentEnumerator
// ----------------------------------------------------------------------------
template <typename TScore, typename TSpec>
class LocalAlignmentEnumerator;
/*!
* @class LocalAlignmentEnumerator
* @headerfile <seqan/align.h>
* @brief Enumeration of local alignments.
*
* @signature template <typename TScore, typename TSpec>
* class LocalAlignmentEnumerator;
*
* @tparam TScore The type of the @link Score @endlink to use for the local alignment.
* @tparam TSpec The tag to use for specializing the enumerator.
*
* This is an abstract class that will only be instantiated through its subclasses.
* See the documentation of the specializations for examples.
*
* @section References
*
* <ul>
* <li>Waterman MS, Eggert M: A new algorithm for best subsequence alignments with application to tRNA-rRNA
* comparisons. J Mol Biol 1987, 197(4):723-728.</li>
* </ul>
*/
/*!
* @class UnbandedLocalAlignmentEnumerator
* @extends LocalAlignmentEnumerator
* @headerfile <seqan/align.h>
* @brief Unbanded enumeration of local alignments using the Waterman-Eggert algorithm.
*
* @signature template <typename TScore>
* class LocalAlignmentEnumerator<TScore, Unbanded>;
*
* @tparam TScore The @link Score @endlink type.
*
* @section Examples
*
* Enumerate all alignments into a @link Align @endlink object.
*
* @code{.cpp}
* SimpleScore scoringScheme(2, -1, -1, -2);
* LocalAlignmentEnumerator<SimpleScore, Unbanded> enumerator(scoringScheme, 5);
*
* Dna5String seqH = "CGAGAGAGACCGAGA";
* Dna5String seqV = "TTCTGAGATCCGTTTTT";
*
* Align<Dna5String> align;
* resize(rows(align), 2);@s
* assignSource(row(align), 0, seqH);
* assignSource(row(align), 1, seqV);
*
* int i = 0;
* while (nextLocalAlignment(align, enumerator))
* {
* std::cout << i << "-th alignment:\n";
* std::cout << align << "\n\n";
* std::cout << "score == " << getScore(enumerator) << "\n";
* }
* @endcode
*/
/*!
* @fn UnbandedLocalAlignmentEnumerator::LocalAlignmentEnumerator
* @brief Constructor.
*
* @signature LocalAlignmentEnumerator::LocalAlignmentEnumerator(scheme[, cutoff]);
*
* @param[in] scheme The @link Score @endlink object to use for the alignment score.
* @param[in] cutoff Alignments with scores <tt>< cutoff</tt> will be discarded (<tt>int</tt>, default 0).
*/
/*!
* @class BandedLocalAlignmentEnumerator
* @extends LocalAlignmentEnumerator
* @headerfile <seqan/align.h>
* @brief Banded enumeration of local alignments using the Waterman-Eggert algorithm.
*
* @signature template <typename TScore>
* class LocalAlignmentEnumerator<TScore, Banded>;
*
* @tparam TScore The @link Score @endlink type.
*
* @section Examples
*
* Enumerate all alignments in the band between -3 and 0 into an @link Align @endlink object.
*
* @code{.cpp}
* SimpleScore scoringScheme(2, -1, -1, -2);
* LocalAlignmentEnumerator<SimpleScore, Banded> enumerator(scoringScheme, -3, 0, 5);
*
* Dna5String seqH = "CGAGAGAGACCGAGA";
* Dna5String seqV = "TTCTGAGATCCGTTTTT";
*
* Align<Dna5String> align;
* resize(rows(align), 2);
* assignSource(row(align), 0, seqH);
* assignSource(row(align), 1, seqV);
*
* int i = 0;
* while (nextLocalAlignment(align, enumerator))
* {
* std::cout << i << "-th alignment:\n";
* std::cout << align << "\n\n";
* std::cout << "score == " << getScore(enumerator) << "\n";
* }
* @endcode
*/
/*!
* @fn BandedLocalAlignmentEnumerator::LocalAlignmentEnumerator
* @brief Constructor.
*
* @signature LocalAlignmentEnumerator::LocalAlignmentEnumerator(scheme, upperDiag, lowerDiag[, cutoff]);
*
* @param[in] scheme The @link Score @endlink object to use for the alignment score.
* @param[in] upperDiag An <tt>int</tt> with the upper diagonal.
* @param[in] lowerDiag An <tt>int</tt> with the lower diagonal.
* @param[in] cutoff Alignments with scores <tt>< cutoff</tt> will be discarded (<tt>int</tt>, default 0).
*/
// ============================================================================
// Metafunctions
// ============================================================================
// ============================================================================
// Functions
// ============================================================================
// ----------------------------------------------------------------------------
// Function getScore()
// ----------------------------------------------------------------------------
/*!
* @fn LocalAlignmentEnumerator#getScore
* @headerfile <seqan/align.h>
* @brief Get current alignment score.
*
* @signature TScoreVal getScore(enumerator);
*
* @param[in] enumerator The LocalAlignmentEnumerator to query.
*
* @return TScoreVal The current alignment score (@link Score#Value @endlink of <tt>TScore</tt>).
*/
// ----------------------------------------------------------------------------
// Function nextLocalAlignment()
// ----------------------------------------------------------------------------
/*!
* @fn LocalAlignmentEnumerator#nextLocalAlignment
* @headerfile <seqan/align.h>
* @brief Compute next suboptimal local alignment.
*
* @signature bool nextLocalAlignment(align, enumerator);
* @signature bool nextLocalAlignment(gapsH, gapsV, enumerator);
*
* @param[in] align @link Align @endlink object to use for the alignment representation.
* @param[in] gapsH @link Gaps @endlink object to use for the first/horizontal sequence in the alignment matrix.
* @param[in] gapsV @link Gaps @endlink object to use for the second/vertical sequence in the alignment matrix.
* @param[in] enumerator The LocalAlignmentEnumerator to advance.
*
* @return bool <tt>true</tt> if another suboptimal alignment above the given threshold was found and <tt> false
* otherwise.
*/
} // namespace seqan2
#endif // #ifndef SEQAN_INCLUDE_SEQAN_ALIGN_LOCAL_ALIGNMENT_ENUMERATION_H_
|